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The map label for this gene is plsC1 [H]

Identifier: 110834778

GI number: 110834778

Start: 2194397

End: 2195146

Strand: Direct

Name: plsC1 [H]

Synonym: ABO_1917

Alternate gene names: 110834778

Gene position: 2194397-2195146 (Clockwise)

Preceding gene: 110834777

Following gene: 110834779

Centisome position: 70.33

GC content: 52.93

Gene sequence:

>750_bases
ATGGTAATGCGATTGTTTTTCTTTCTGTATAGTTGGCTGATCTTTGTGCCGCTCATGCTGGCGACCACGCTGGTGGCAGG
CTTGGTCTGTTTACTACTTATTCCTTTTCTACCCACTGACAAAGTCGCAAAACTCACCGCCGTACCTTGGGCCAGGCTCT
GCCTTCTTTATAGTGGTGTGCGAGTAGAGGTTGATGGCCGCCATCACCTCCAGCCCGGCCAAAGTTACGTCATCGTCGCC
AACCACCTCAGTCAATTCGATATTTTTGTATTGTACGGTTATCTAGGCATAGATTTTCGTTGGGTAATGAAACACGAACT
ACGCAAGGTTCCGATTATCGGTATCTGCAGCGAAAAACTGGGCCATATTTTTATTAATCGGTCCGACACTGAAGCAGCCG
TTGCCTCCTTGAATAACGCCCGCGCACGCTTGGCCAATGGGGCCAGCGTGTTATTCTTTCCTGAAGGCACCCGCAGCCGC
GATGGACAATTGAAACCCTTCAAAAAAGGCGCCTTCAAGATGGCTCAGGCGCTGCAGCTACCCGTGCTGCCTATCACCCT
GTCGGGAACATTCGACATTTTGCCCGCCGGAACCTTAAGACTGCATCCCGGCGCCACCGCTCGCCTGGTTATGCACCCCG
CACTCACAGTAACCGGCAACACTGAGGCCGAACTGCAAGCTCTCGTCCAGCAAAGCCGCAGCGCCATTGCCGCCCCGTTA
AGGGACAGCTCATCACAACTACCGTTCTAA

Upstream 100 bases:

>100_bases
GCATCATCCAAAGGTAACCAACGTAAATGCTGGCCTGTCATTTTCGGCCAGACCTCCGCTACCATAGCACTCAGTTTCTG
TACGAATCGGAGAGCATCAG

Downstream 100 bases:

>100_bases
CCACAGCGACAGCCCATTGTGTCGCCAACGTCACAAGGCCAGCTCCTTGTCTGACAAGATTGGCCCATTCTGCAGTGGCA
AAGTGTCTACACTCGGTCGC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVMRLFFFLYSWLIFVPLMLATTLVAGLVCLLLIPFLPTDKVAKLTAVPWARLCLLYSGVRVEVDGRHHLQPGQSYVIVA
NHLSQFDIFVLYGYLGIDFRWVMKHELRKVPIIGICSEKLGHIFINRSDTEAAVASLNNARARLANGASVLFFPEGTRSR
DGQLKPFKKGAFKMAQALQLPVLPITLSGTFDILPAGTLRLHPGATARLVMHPALTVTGNTEAELQALVQQSRSAIAAPL
RDSSSQLPF

Sequences:

>Translated_249_residues
MVMRLFFFLYSWLIFVPLMLATTLVAGLVCLLLIPFLPTDKVAKLTAVPWARLCLLYSGVRVEVDGRHHLQPGQSYVIVA
NHLSQFDIFVLYGYLGIDFRWVMKHELRKVPIIGICSEKLGHIFINRSDTEAAVASLNNARARLANGASVLFFPEGTRSR
DGQLKPFKKGAFKMAQALQLPVLPITLSGTFDILPAGTLRLHPGATARLVMHPALTVTGNTEAELQALVQQSRSAIAAPL
RDSSSQLPF
>Mature_249_residues
MVMRLFFFLYSWLIFVPLMLATTLVAGLVCLLLIPFLPTDKVAKLTAVPWARLCLLYSGVRVEVDGRHHLQPGQSYVIVA
NHLSQFDIFVLYGYLGIDFRWVMKHELRKVPIIGICSEKLGHIFINRSDTEAAVASLNNARARLANGASVLFFPEGTRSR
DGQLKPFKKGAFKMAQALQLPVLPITLSGTFDILPAGTLRLHPGATARLVMHPALTVTGNTEAELQALVQQSRSAIAAPL
RDSSSQLPF

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=200, Percent_Identity=34, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI15100175, Length=200, Percent_Identity=34, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI6041665, Length=225, Percent_Identity=29.7777777777778, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1789395, Length=202, Percent_Identity=26.2376237623762, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=223, Percent_Identity=28.2511210762332, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568319, Length=138, Percent_Identity=31.1594202898551, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=246, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641614, Length=224, Percent_Identity=33.0357142857143, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24641612, Length=224, Percent_Identity=33.0357142857143, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI281364648, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24582856, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24582854, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27465; Mature: 27465

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMRLFFFLYSWLIFVPLMLATTLVAGLVCLLLIPFLPTDKVAKLTAVPWARLCLLYSGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHCCC
RVEVDGRHHLQPGQSYVIVANHLSQFDIFVLYGYLGIDFRWVMKHELRKVPIIGICSEKL
EEEECCCCCCCCCCEEEEEECCCCHHHHHEEEHHHCCCHHEEEHHHHHCCCEEEECCCCC
GHIFINRSDTEAAVASLNNARARLANGASVLFFPEGTRSRDGQLKPFKKGAFKMAQALQL
CEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
PVLPITLSGTFDILPAGTLRLHPGATARLVMHPALTVTGNTEAELQALVQQSRSAIAAPL
CEEEEEECCCEEECCCCEEEECCCCCEEEEEECEEEEECCCHHHHHHHHHHHHHHHCCCC
RDSSSQLPF
CCCCCCCCC
>Mature Secondary Structure
MVMRLFFFLYSWLIFVPLMLATTLVAGLVCLLLIPFLPTDKVAKLTAVPWARLCLLYSGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHCCC
RVEVDGRHHLQPGQSYVIVANHLSQFDIFVLYGYLGIDFRWVMKHELRKVPIIGICSEKL
EEEECCCCCCCCCCEEEEEECCCCHHHHHEEEHHHCCCHHEEEHHHHHCCCEEEECCCCC
GHIFINRSDTEAAVASLNNARARLANGASVLFFPEGTRSRDGQLKPFKKGAFKMAQALQL
CEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCC
PVLPITLSGTFDILPAGTLRLHPGATARLVMHPALTVTGNTEAELQALVQQSRSAIAAPL
CEEEEEECCCEEECCCCEEEECCCCCEEEEEECEEEEECCCHHHHHHHHHHHHHHHCCCC
RDSSSQLPF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]