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The map label for this gene is coxC [H]

Identifier: 110834758

GI number: 110834758

Start: 2174518

End: 2175399

Strand: Reverse

Name: coxC [H]

Synonym: ABO_1897

Alternate gene names: 110834758

Gene position: 2175399-2174518 (Counterclockwise)

Preceding gene: 110834759

Following gene: 110834754

Centisome position: 69.72

GC content: 52.95

Gene sequence:

>882_bases
ATGGCTACTGAAAAATACTACGTTCCAGAGAGCAGCCCTTGGCCGTTGACGGCTTCCATAGGTTTGTTCATGACCGCTAT
CGGCGGTGCGCATTTTATTCAGCAGAGCACCATGGCGGATATGGAGCCTAGCTTCATTGGTAAACCGCTATTCTTCCTAG
GCCTGACCTGGTTGCTGGTAGTGATCGCCCTGTGGTGGCGTGACACTATTAAGGAGTCCGTCGGTGGCCTGCACAGCAAT
CAGTTGGGCGGTTCCTACCGTCAGGGCATGCTGTGGTTTATCTTTTCTGAGGTAATGTTCTTTGCGGCCTTCTTTGGCGC
TATGTTCTACACCCGTTGGCTGATCCTGCCTTGGTTGTCTGGGGAAGGCAGCAACGCCATGACCCACGAACTGCTATGGC
CGAACTTTCAAGCCATGTGGCCGCTGACTGTGACCCCTGCGGGTGATACCACACAAGCCATGGGCGCATGGGGCTTGCCA
GCGATCAACACGGCTATCCTGTTGGTGTCCTCTGTAACCCTGACAATCGCTCACCACGCCTTGTTAGAAGGCAAGCGTGG
CACTGTGATTGCCTTCCAGGCGGCTACAGTGATCCTCGGTGTGATCTTCCTGTTCTTGCAGGTGGAAGAATATATTCATG
CTTATACCGAGCTCGGATTGACGTTGGATGCGGGTATCTACGGCAGCCTGTTCTTCCTGCTCACTGGGTTCCATGGTGCG
CACGTAACCATCGGTACCATCTTCTTATTCGTGACCTTGCTGCGTGTGATCAAGGGCCACTTTGATGAAGAGAATAACTT
TGCCTGGGAAGCCGGTGCCTGGTATTGGCACTTTGTGGACGTGGTGTGGTTGTTCTTGTTTATTACGGTGTATTGGTTGT
AA

Upstream 100 bases:

>100_bases
ACTCTGTCATACACGATCTTCGATGTGACAGAGCGGGTCGCCGGTAAAAACAACAGCGTGGCTGTGAACTAGAACAGCCG
GTTGTAGAGGAGATTTTTTA

Downstream 100 bases:

>100_bases
TCGGCGGCGCTGCACGCGCCACGCGATAAGTAACACGTAAAAAGCCGCGCTTCGAAAGAAGCGCGGCTTTTTTGTTTGAA
AGTTTAATGCTGTATTCAGG

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MATEKYYVPESSPWPLTASIGLFMTAIGGAHFIQQSTMADMEPSFIGKPLFFLGLTWLLVVIALWWRDTIKESVGGLHSN
QLGGSYRQGMLWFIFSEVMFFAAFFGAMFYTRWLILPWLSGEGSNAMTHELLWPNFQAMWPLTVTPAGDTTQAMGAWGLP
AINTAILLVSSVTLTIAHHALLEGKRGTVIAFQAATVILGVIFLFLQVEEYIHAYTELGLTLDAGIYGSLFFLLTGFHGA
HVTIGTIFLFVTLLRVIKGHFDEENNFAWEAGAWYWHFVDVVWLFLFITVYWL

Sequences:

>Translated_293_residues
MATEKYYVPESSPWPLTASIGLFMTAIGGAHFIQQSTMADMEPSFIGKPLFFLGLTWLLVVIALWWRDTIKESVGGLHSN
QLGGSYRQGMLWFIFSEVMFFAAFFGAMFYTRWLILPWLSGEGSNAMTHELLWPNFQAMWPLTVTPAGDTTQAMGAWGLP
AINTAILLVSSVTLTIAHHALLEGKRGTVIAFQAATVILGVIFLFLQVEEYIHAYTELGLTLDAGIYGSLFFLLTGFHGA
HVTIGTIFLFVTLLRVIKGHFDEENNFAWEAGAWYWHFVDVVWLFLFITVYWL
>Mature_292_residues
ATEKYYVPESSPWPLTASIGLFMTAIGGAHFIQQSTMADMEPSFIGKPLFFLGLTWLLVVIALWWRDTIKESVGGLHSNQ
LGGSYRQGMLWFIFSEVMFFAAFFGAMFYTRWLILPWLSGEGSNAMTHELLWPNFQAMWPLTVTPAGDTTQAMGAWGLPA
INTAILLVSSVTLTIAHHALLEGKRGTVIAFQAATVILGVIFLFLQVEEYIHAYTELGLTLDAGIYGSLFFLLTGFHGAH
VTIGTIFLFVTLLRVIKGHFDEENNFAWEAGAWYWHFVDVVWLFLFITVYWL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=291, Percent_Identity=37.4570446735395, Blast_Score=157, Evalue=8e-39,
Organism=Escherichia coli, GI1786633, Length=147, Percent_Identity=30.6122448979592, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6226542, Length=291, Percent_Identity=30.9278350515464, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32943; Mature: 32812

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEKYYVPESSPWPLTASIGLFMTAIGGAHFIQQSTMADMEPSFIGKPLFFLGLTWLLV
CCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
VIALWWRDTIKESVGGLHSNQLGGSYRQGMLWFIFSEVMFFAAFFGAMFYTRWLILPWLS
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GEGSNAMTHELLWPNFQAMWPLTVTPAGDTTQAMGAWGLPAINTAILLVSSVTLTIAHHA
CCCCCCCCHHHCCCCCCEECCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLEGKRGTVIAFQAATVILGVIFLFLQVEEYIHAYTELGLTLDAGIYGSLFFLLTGFHGA
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCC
HVTIGTIFLFVTLLRVIKGHFDEENNFAWEAGAWYWHFVDVVWLFLFITVYWL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATEKYYVPESSPWPLTASIGLFMTAIGGAHFIQQSTMADMEPSFIGKPLFFLGLTWLLV
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
VIALWWRDTIKESVGGLHSNQLGGSYRQGMLWFIFSEVMFFAAFFGAMFYTRWLILPWLS
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GEGSNAMTHELLWPNFQAMWPLTVTPAGDTTQAMGAWGLPAINTAILLVSSVTLTIAHHA
CCCCCCCCHHHCCCCCCEECCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLEGKRGTVIAFQAATVILGVIFLFLQVEEYIHAYTELGLTLDAGIYGSLFFLLTGFHGA
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCC
HVTIGTIFLFVTLLRVIKGHFDEENNFAWEAGAWYWHFVDVVWLFLFITVYWL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]