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The map label for this gene is fabR [H]

Identifier: 110834579

GI number: 110834579

Start: 1956338

End: 1956988

Strand: Direct

Name: fabR [H]

Synonym: ABO_1718

Alternate gene names: 110834579

Gene position: 1956338-1956988 (Clockwise)

Preceding gene: 110834575

Following gene: 110834580

Centisome position: 62.7

GC content: 53.61

Gene sequence:

>651_bases
ATGACAAAGGAAAGCACCAGCAGAACTCGCAAGCCTAAACGGGGACAGACCCGGGAAGCACTGATGACGGCTGCGTTGGA
GCTGGTGGTCAAAAAGGCCCCCTTTTCTGCCCTGAGTCTGCGGGAAGTCACCAAAAAAGCCGGGGTAGTACCGACTGCCT
TTTATCGCCATTTCTCGGACATGAGTGCCATGGGCCTCACCTTGCTGGACGAATCCTTCCGTACTCTGCGTCAGATGATG
CGCCAAGTACGCCAGCAGGAATTACCCAACGAGCACATGTTGCGCAGCTCCATGGAAACTTACTTCACCTATGTGCGTAA
CAACCGCGCCCACTTCCTGTTCGTATCCAAGGAACTGGCTAGTGGCACCCCCACCATGCGCAATGCCATTCGCCGCGAAA
TCCGCATGTTCACCAACGAACTGGCGATGGACATGGCACGCTTCCCCTTCCTCGATCACGTTAATGCCGAAGACCTACAA
ATGATGGCAGGCCTGGTTGTTAACAATGTCACCGCATTGACACAGGAAATGTTGGAACTGGAAGAAACGGATGAAACGGG
CCAGCAAGAAGTGCTGATTACCGCAGAGAAGCAACTACGCCTTATTTACTTCGGCGTGGGCATGTGGCGTTCAGACAAAA
ACCGTTCCTGA

Upstream 100 bases:

>100_bases
GTCGTTTTTTTTCATGGTGTTATAACTTGCCATAGGGAATTGGTTGCATCACAAGCCCGCACAGAAGAGAATAAGCAGCT
GATTTTGGAGGCAAAAAACG

Downstream 100 bases:

>100_bases
ACAAGTTTCATCCTTTCTAGCCCTGTGTCGAGCACCCTGTGCTTAACTCACCAGCCACCCTGTCTATACGGCCAATAGCG
ACCCGGCTGCCCTGCTCTAT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTKESTSRTRKPKRGQTREALMTAALELVVKKAPFSALSLREVTKKAGVVPTAFYRHFSDMSAMGLTLLDESFRTLRQMM
RQVRQQELPNEHMLRSSMETYFTYVRNNRAHFLFVSKELASGTPTMRNAIRREIRMFTNELAMDMARFPFLDHVNAEDLQ
MMAGLVVNNVTALTQEMLELEETDETGQQEVLITAEKQLRLIYFGVGMWRSDKNRS

Sequences:

>Translated_216_residues
MTKESTSRTRKPKRGQTREALMTAALELVVKKAPFSALSLREVTKKAGVVPTAFYRHFSDMSAMGLTLLDESFRTLRQMM
RQVRQQELPNEHMLRSSMETYFTYVRNNRAHFLFVSKELASGTPTMRNAIRREIRMFTNELAMDMARFPFLDHVNAEDLQ
MMAGLVVNNVTALTQEMLELEETDETGQQEVLITAEKQLRLIYFGVGMWRSDKNRS
>Mature_215_residues
TKESTSRTRKPKRGQTREALMTAALELVVKKAPFSALSLREVTKKAGVVPTAFYRHFSDMSAMGLTLLDESFRTLRQMMR
QVRQQELPNEHMLRSSMETYFTYVRNNRAHFLFVSKELASGTPTMRNAIRREIRMFTNELAMDMARFPFLDHVNAEDLQM
MAGLVVNNVTALTQEMLELEETDETGQQEVLITAEKQLRLIYFGVGMWRSDKNRS

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=201, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24996; Mature: 24865

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKESTSRTRKPKRGQTREALMTAALELVVKKAPFSALSLREVTKKAGVVPTAFYRHFSD
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MSAMGLTLLDESFRTLRQMMRQVRQQELPNEHMLRSSMETYFTYVRNNRAHFLFVSKELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHH
SGTPTMRNAIRREIRMFTNELAMDMARFPFLDHVNAEDLQMMAGLVVNNVTALTQEMLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EETDETGQQEVLITAEKQLRLIYFGVGMWRSDKNRS
HHCCCCCCCEEEEEHHHHEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TKESTSRTRKPKRGQTREALMTAALELVVKKAPFSALSLREVTKKAGVVPTAFYRHFSD
CCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MSAMGLTLLDESFRTLRQMMRQVRQQELPNEHMLRSSMETYFTYVRNNRAHFLFVSKELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHH
SGTPTMRNAIRREIRMFTNELAMDMARFPFLDHVNAEDLQMMAGLVVNNVTALTQEMLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EETDETGQQEVLITAEKQLRLIYFGVGMWRSDKNRS
HHCCCCCCCEEEEEHHHHEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA