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The map label for this gene is mtnB

Identifier: 110834306

GI number: 110834306

Start: 1648294

End: 1648929

Strand: Direct

Name: mtnB

Synonym: ABO_1445

Alternate gene names: 110834306

Gene position: 1648294-1648929 (Clockwise)

Preceding gene: 110834305

Following gene: 110834307

Centisome position: 52.83

GC content: 54.87

Gene sequence:

>636_bases
ATGCCTGAGCGCCCCTACTCTACCACTGTCTTCCGCGACGCTGCCCGAGCATTGGCGGCCACCGGACAACGGATTTACGC
TAATGGCTGGTCGCCTGCCACCAGCAGTAATTACTCTCAGCGGCTCAATACCGACTTTGCCGCCGTTACTCAATCTGGCA
AAGACAAAGGCCTACTGCGAGAAACGGATATCATGGCTGTGAACATGGACGGCCAGCCGGCTTCCAGCGGCAAGCCCTCT
GCAGAAACCTTGCTGCATACCCAACTTTACCGCTTCGATGGCAACATTCAGGCGGTACTTCACACCCATAGCCATGCCTC
CACCGTGCTGACCATGCACTGGCCCGCTAACAGCATTACTTTAGAAGGTTATGAGCTACTCAAAGCCCTGCAAGGGATTA
CCAGCCATAACAGCCGGTTAACTATTCCTGTATTTGAAAATACCCAGGATATCGCTGCCTTGGCAGCCAAAGTCGATCAG
CAAATGCGCTCCGGCCACATCAGCCACGCCTATCTTATTCGCGGCCACGGCTTGTATACCTGGGCTAACGATCTGCCAAC
CTGTTACCGGCAGCTGGAAGCACTGGAAACCCTGCTGGCCATTGAATTGGAATGCCGAAGGCTGCGTGGCAGCTAA

Upstream 100 bases:

>100_bases
GCGCAATTGATCACCGCCATCGTTACCGAACGAGGCGTGGTCCACCGCCCGGATACGGCCAAAATTAACAGCCATCTGGC
TCAGACCAAGGAAAGCTAGC

Downstream 100 bases:

>100_bases
ATCAGCATTGTCTCAATGTGCCAATAAATATTGCAGATATGGAGAACCGGCTATGCATAGCGAACTGAAAGTCTTTTCTG
ATCAGGCCCCCGGGCGAGTG

Product: sugar aldolase

Products: NA

Alternate protein names: MTRu-1-P dehydratase

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MPERPYSTTVFRDAARALAATGQRIYANGWSPATSSNYSQRLNTDFAAVTQSGKDKGLLRETDIMAVNMDGQPASSGKPS
AETLLHTQLYRFDGNIQAVLHTHSHASTVLTMHWPANSITLEGYELLKALQGITSHNSRLTIPVFENTQDIAALAAKVDQ
QMRSGHISHAYLIRGHGLYTWANDLPTCYRQLEALETLLAIELECRRLRGS

Sequences:

>Translated_211_residues
MPERPYSTTVFRDAARALAATGQRIYANGWSPATSSNYSQRLNTDFAAVTQSGKDKGLLRETDIMAVNMDGQPASSGKPS
AETLLHTQLYRFDGNIQAVLHTHSHASTVLTMHWPANSITLEGYELLKALQGITSHNSRLTIPVFENTQDIAALAAKVDQ
QMRSGHISHAYLIRGHGLYTWANDLPTCYRQLEALETLLAIELECRRLRGS
>Mature_210_residues
PERPYSTTVFRDAARALAATGQRIYANGWSPATSSNYSQRLNTDFAAVTQSGKDKGLLRETDIMAVNMDGQPASSGKPSA
ETLLHTQLYRFDGNIQAVLHTHSHASTVLTMHWPANSITLEGYELLKALQGITSHNSRLTIPVFENTQDIAALAAKVDQQ
MRSGHISHAYLIRGHGLYTWANDLPTCYRQLEALETLLAIELECRRLRGS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily

Homologues:

Organism=Homo sapiens, GI166235186, Length=197, Percent_Identity=24.3654822335025, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNB_ALCBS (Q0VPK5)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_693165.1
- ProteinModelPortal:   Q0VPK5
- SMR:   Q0VPK5
- STRING:   Q0VPK5
- GeneID:   4212622
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1445
- NMPDR:   fig|393595.12.peg.1451
- eggNOG:   COG0235
- HOGENOM:   HBG337716
- OMA:   EFLFECE
- BioCyc:   ABOR393595:ABO_1445-MONOMER
- HAMAP:   MF_01677
- InterPro:   IPR001303
- InterPro:   IPR017714
- Gene3D:   G3DSA:3.40.225.10
- TIGRFAMs:   TIGR03328

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.2.1.109

Molecular weight: Translated: 23326; Mature: 23194

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERPYSTTVFRDAARALAATGQRIYANGWSPATSSNYSQRLNTDFAAVTQSGKDKGLLR
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCEE
ETDIMAVNMDGQPASSGKPSAETLLHTQLYRFDGNIQAVLHTHSHASTVLTMHWPANSIT
ECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCEE
LEGYELLKALQGITSHNSRLTIPVFENTQDIAALAAKVDQQMRSGHISHAYLIRGHGLYT
ECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEE
WANDLPTCYRQLEALETLLAIELECRRLRGS
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PERPYSTTVFRDAARALAATGQRIYANGWSPATSSNYSQRLNTDFAAVTQSGKDKGLLR
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCEE
ETDIMAVNMDGQPASSGKPSAETLLHTQLYRFDGNIQAVLHTHSHASTVLTMHWPANSIT
ECCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCEE
LEGYELLKALQGITSHNSRLTIPVFENTQDIAALAAKVDQQMRSGHISHAYLIRGHGLYT
ECHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEE
WANDLPTCYRQLEALETLLAIELECRRLRGS
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA