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The map label for this gene is czcC3 [H]

Identifier: 110834242

GI number: 110834242

Start: 1572287

End: 1573585

Strand: Direct

Name: czcC3 [H]

Synonym: ABO_1381

Alternate gene names: 110834242

Gene position: 1572287-1573585 (Clockwise)

Preceding gene: 110834233

Following gene: 110834243

Centisome position: 50.39

GC content: 58.66

Gene sequence:

>1299_bases
ATGAAATGCCGAACCTCCGGCTGGCGCCTTGTTGCGTCGTCCTTGCTGTGCCTGTTCGCGCCAGGCCATCTCATCGCGGG
TAATACATCGGTGCCAATGGGCACCGAGATTACCCTGCAAGACGTGCTCAGCCGCACCGTAGAGCAGAACCCAGCGCTTG
GCGTTTACCCCTATCGGCTCAGGGCAGCGGATGCGGCGGTGCTCCAGTCCAGCCTTGGGCCGCAGCCAGAACTGTCCGTT
GAGGTGGAAAATATTGCCGGAGACGCACCATTGAATGGCGTTGAAGGTGCACAAATCACTGTTGCCTTGAGCCAGCTGAT
CGAGCTTGGCAACAAGCGAAATTCACGTAATGAGGTGGCGACTCGCGCTCTCAATACGGAACAACAGGGCTACGCTATCG
CACGGCTCGATGTGCTGGGTGAAGCCGTGACTCGTTACATTGCATTGGCGCGTTTTGAAGAAGAATTGGCACTGGCTGAA
CGCACATTGGCTTTAGCGGAAAAAGCAAAACAGGCGGCACGCCGTCGTGTTAATGCCGGTGCGGCCTCGAAGGCGGATTT
AACCCGAATGACCCTCGCCAGCCGGCATGCGGATATTGCCCGCCGGCGCGCTGATATGGAGCGTGGCCGAGCCAGCCAGC
AACTGGCTGCGCTTTGGGGCCAGCAAGGCGCAGATCAACTGCACCCCGCAACCTCGTTGCGGCCGCTTCCCAAGCTTCCA
CCGCGCGAGCAAATTCTGGACCAGCTGGAGCAGGCTCCGCAATTGCTGCAGCTGGCGAGCGAAACGCGCCTGCATGCGGC
CCAGAGCCGCCTGGCCAATGCCCGTGGCAGCCGCGATGTCACCGTCTCTGTTGGCGCGCGCCATGATCGAGTGGACAACA
ACAATACCCTGGTGCTGGGGTTCTCTGTTCCGCTTGGTCTGAAGAATCCTAACCGCGGCAATATAGCCCGAGCCGAATCA
CAACTGGCTGCCAGTGAAGCACAGCTACAGGCCCGCAGGATTGAACTGGTGGCAACGCTGGACACCCTCTATCGCTCACT
GAATCTGTTACGTGAAGAGCTCGCGCTCATTGATGAGAGCGCGTTGCCCTTGGCCAGACAACTGTATGCAGACATCCAAA
AGGGCTATCGCTCCGGTCGCTACAGCCTGCTTGAGCTGATCGATGCCCAGCAAGAGCAACTTAATCTGGAATACCGGGCC
ATTAACCTCGCCGCGCAGTTTCACCTGCAACGAAACGAACTGGAACGCCTCACTGGCTTGCCTTTTTCCCAGGCTGACGA
ACAGGAGATTTCCCAATGA

Upstream 100 bases:

>100_bases
CTCTCTTGTCACGCAGCCTCCTGTGCCACCTCCCAATCGCAACGGATTGATCTGATTTTCGCCGGCGATCTTCGCCGCAA
TCCGTTATCGGGAGATTTTC

Downstream 100 bases:

>100_bases
AAATGCTAGTAACGCTTTCCACGCTTTATCTCCTGACACTTTCCTCTCTGGTAACCGCCAGTGGTGGCCATGGGCACGGT
GAAGACGATCATGACGCACA

Product: cobalt/zinc/cadmium efflux RND transporter outermembrane protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKCRTSGWRLVASSLLCLFAPGHLIAGNTSVPMGTEITLQDVLSRTVEQNPALGVYPYRLRAADAAVLQSSLGPQPELSV
EVENIAGDAPLNGVEGAQITVALSQLIELGNKRNSRNEVATRALNTEQQGYAIARLDVLGEAVTRYIALARFEEELALAE
RTLALAEKAKQAARRRVNAGAASKADLTRMTLASRHADIARRRADMERGRASQQLAALWGQQGADQLHPATSLRPLPKLP
PREQILDQLEQAPQLLQLASETRLHAAQSRLANARGSRDVTVSVGARHDRVDNNNTLVLGFSVPLGLKNPNRGNIARAES
QLAASEAQLQARRIELVATLDTLYRSLNLLREELALIDESALPLARQLYADIQKGYRSGRYSLLELIDAQQEQLNLEYRA
INLAAQFHLQRNELERLTGLPFSQADEQEISQ

Sequences:

>Translated_432_residues
MKCRTSGWRLVASSLLCLFAPGHLIAGNTSVPMGTEITLQDVLSRTVEQNPALGVYPYRLRAADAAVLQSSLGPQPELSV
EVENIAGDAPLNGVEGAQITVALSQLIELGNKRNSRNEVATRALNTEQQGYAIARLDVLGEAVTRYIALARFEEELALAE
RTLALAEKAKQAARRRVNAGAASKADLTRMTLASRHADIARRRADMERGRASQQLAALWGQQGADQLHPATSLRPLPKLP
PREQILDQLEQAPQLLQLASETRLHAAQSRLANARGSRDVTVSVGARHDRVDNNNTLVLGFSVPLGLKNPNRGNIARAES
QLAASEAQLQARRIELVATLDTLYRSLNLLREELALIDESALPLARQLYADIQKGYRSGRYSLLELIDAQQEQLNLEYRA
INLAAQFHLQRNELERLTGLPFSQADEQEISQ
>Mature_432_residues
MKCRTSGWRLVASSLLCLFAPGHLIAGNTSVPMGTEITLQDVLSRTVEQNPALGVYPYRLRAADAAVLQSSLGPQPELSV
EVENIAGDAPLNGVEGAQITVALSQLIELGNKRNSRNEVATRALNTEQQGYAIARLDVLGEAVTRYIALARFEEELALAE
RTLALAEKAKQAARRRVNAGAASKADLTRMTLASRHADIARRRADMERGRASQQLAALWGQQGADQLHPATSLRPLPKLP
PREQILDQLEQAPQLLQLASETRLHAAQSRLANARGSRDVTVSVGARHDRVDNNNTLVLGFSVPLGLKNPNRGNIARAES
QLAASEAQLQARRIELVATLDTLYRSLNLLREELALIDESALPLARQLYADIQKGYRSGRYSLLELIDAQQEQLNLEYRA
INLAAQFHLQRNELERLTGLPFSQADEQEISQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47393; Mature: 47393

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCRTSGWRLVASSLLCLFAPGHLIAGNTSVPMGTEITLQDVLSRTVEQNPALGVYPYRL
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHH
RAADAAVLQSSLGPQPELSVEVENIAGDAPLNGVEGAQITVALSQLIELGNKRNSRNEVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
TRALNTEQQGYAIARLDVLGEAVTRYIALARFEEELALAERTLALAEKAKQAARRRVNAG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AASKADLTRMTLASRHADIARRRADMERGRASQQLAALWGQQGADQLHPATSLRPLPKLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PREQILDQLEQAPQLLQLASETRLHAAQSRLANARGSRDVTVSVGARHDRVDNNNTLVLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEE
FSVPLGLKNPNRGNIARAESQLAASEAQLQARRIELVATLDTLYRSLNLLREELALIDES
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALPLARQLYADIQKGYRSGRYSLLELIDAQQEQLNLEYRAINLAAQFHLQRNELERLTGL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHCC
PFSQADEQEISQ
CCCCCCHHHHCC
>Mature Secondary Structure
MKCRTSGWRLVASSLLCLFAPGHLIAGNTSVPMGTEITLQDVLSRTVEQNPALGVYPYRL
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHH
RAADAAVLQSSLGPQPELSVEVENIAGDAPLNGVEGAQITVALSQLIELGNKRNSRNEVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
TRALNTEQQGYAIARLDVLGEAVTRYIALARFEEELALAERTLALAEKAKQAARRRVNAG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AASKADLTRMTLASRHADIARRRADMERGRASQQLAALWGQQGADQLHPATSLRPLPKLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PREQILDQLEQAPQLLQLASETRLHAAQSRLANARGSRDVTVSVGARHDRVDNNNTLVLG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEE
FSVPLGLKNPNRGNIARAESQLAASEAQLQARRIELVATLDTLYRSLNLLREELALIDES
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ALPLARQLYADIQKGYRSGRYSLLELIDAQQEQLNLEYRAINLAAQFHLQRNELERLTGL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHCC
PFSQADEQEISQ
CCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]