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The map label for this gene is ppsA [C]

Identifier: 110834183

GI number: 110834183

Start: 1498283

End: 1500316

Strand: Direct

Name: ppsA [C]

Synonym: ABO_1322

Alternate gene names: 110834183

Gene position: 1498283-1500316 (Clockwise)

Preceding gene: 110834182

Following gene: 110834184

Centisome position: 48.02

GC content: 53.64

Gene sequence:

>2034_bases
ATGAGCATTGAAGTACTGACTGCGGATATTGAGGGCGGCGAAAACTTGCAGCGTTGGGCTGCCATGGGCTTACCTATTCC
GCCAAGTTGGCGCATTAGTCGTCAAGTTATAACAGGCAATTCTGTTCAGTGGTTGACGCAACAGCTTGCTACCTTGGCAC
ACATGTTTTCAGGCGACCGTTACTGGGTGTTGCAACAAGGGCCAATGAATCCGGAGTCACGTCGAGAAAGCCTGTTAAAT
CTGGATTCAGATGAAGCGCTCGCTGCGGCACTTCAACGCATTTTCCAGCGTGCTCCAGGGCCAGATCATGTGGTGATTCA
AGCGTTACCAAAACAACACGCTGCCGGCGTGCTATTTACCCGACACCCTTTGCGCCAAGATCTACCGCATATGGTGGTTG
AAGGAGTCGTAGGTGGTAACAGTGAACGTCAGCGGCTTATTTTCGATGAAAATGACCGGTTGGTGTATGCCCCTGAGGCT
CAATTGCCTTTAAACCAACAGGTCGGTGAAGCCCTTTTTTGTCGGCTTCACCGTCAGCTTAAAGATAATTTTAAACATCC
ACAGGCTGGAGAGTGGGTTTTTGATGGTGAGCAACTATGGCTGTTGCAAACCCTTCCTGTAGGTTCGCTCTCTGTACCCA
AAGAAGCCTGGGCCCGCCGGGCTGGGGTAGGGCTTTTCAATCAGGTGGAAACTCCTCTGTGGTATACCCTGGCCGGGCGA
TGGTTAAAAGCCGGCTTCTGGGAACCGCTAGTAGAAAGTGCCGGGTGGAAAGGGCTCGCCAAGGTTGAACCTTACCGGCG
TCAACATAGCCATATTTACACCAATTGTGCGTTCTTTCGTGAGCTTCAGCGCGAACACCCAGGGGCCGCACGATTTGTGC
CACCAGCATGGCAATCTCTGGAATGTGACCCTGCATCTGCTCCACAAACGGTAGGCTCCTCATTTTCTAAGAGCATTAAC
CAATGGCGGCAGAGCTGGATCTTGTTGGAGCTGTCACTGAATGTGCAGAAGTGGAAGCAACCAGAGGTAACCCGTGAGGG
CCTATGGCGCGCTTTTATGCGCCTTGATGCCATGGGAGAGTCCCTTAGCCGCGTAGAAGGTGAGCTTGCCTACCTAAGGC
TGGCAGATGCATTGGTCGATTATCGTGCGCCTCTGCCTTTGACGTTGCTGGTTACGCCTACTGAACTTCGGGCCCTGCAA
TCCCTGGTGGCTGGCGAGGTGGATTCGGTACGTGATACAGCATTACGACCGGGTGTTGATCCTGTCCATGCCCCCTTGAA
TGAGGGGCCGGCTCAAGCGTCTACACTTAATAGATTGCAACAACCGGGAATCGTTAGCGACGCCCCGTTGGCGCAACTCT
CAGATGCGGACGAGCAGGCATTTAAAATGGCACGAACCGCTCGCGGGCTGCGTTTTGCTATTGGTAATCGTCTACGGCAA
CTACTTCGTTCCATGGCGGCTATTGCGGTTGAGCAAGGGACGCTACAACACCTTGATGATATTCATTTTCTGTACTTTGA
TGAGCTTTGGCAGCTGTGGATGGGATCAGCATTGCCTGCCAGCGCCAATAAAGCTGTGATCGGTGATCGTAAACTGCGTT
ACCTTGATGATGGCCTACAGGGAGCGCCGGACTGGAAGATGGACCAAGTAGGGTACGGTTTTGGCGGCGGACAGCGTCTT
AGCCCTCTATTACGTGGGCTGACGCTGGTGCCTGGTTCTGCTGAAGGTGCCATTCGCCGTGTATGCAGTGCCTGGTGCCT
TAACAAGGTACAGCCTGGCGACATTGTTGTGGTAGATGAGGTCGATCCCGCTTGGTTGCCCTGGCTGGTACAAGCAGCAG
GGCTGGTGATTGCCCAACAGGACCCTGCTAACGGCGCGGCTAGCTTAGCTGTGACATATGGGATTCCCGCTATTTGGGGC
GCCAGCGACGTGATGCATAGTGTTCAGGATGCGCTGCAGGGCACTCTAGACGCGACCCATGGCAAGCTTGCCATGGCGTC
GGATATGAATAACGATGACGTTACTGTGCAGTAA

Upstream 100 bases:

>100_bases
GCCAGTTCTTTACTGGTTCGGTTTGTGGGGAGCGCGCATAGTGCTTCAGCACCCAGCAGATAACTGACAAACGATCGGCA
AAACAAATAAGAAACGGCTA

Downstream 100 bases:

>100_bases
CCTGGGTAGGCCGAGAAGCTCGCCTAGGTAAGTGGTTGTTTTCCTTTTAAAGGTGAGAGGTGAGAGCCGTGCCCCAACCC
CCGACCCAAGAAGAAGATAC

Product: hypothetical protein

Products: AMP; H+; Phosphoenolpyruvate; Phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MSIEVLTADIEGGENLQRWAAMGLPIPPSWRISRQVITGNSVQWLTQQLATLAHMFSGDRYWVLQQGPMNPESRRESLLN
LDSDEALAAALQRIFQRAPGPDHVVIQALPKQHAAGVLFTRHPLRQDLPHMVVEGVVGGNSERQRLIFDENDRLVYAPEA
QLPLNQQVGEALFCRLHRQLKDNFKHPQAGEWVFDGEQLWLLQTLPVGSLSVPKEAWARRAGVGLFNQVETPLWYTLAGR
WLKAGFWEPLVESAGWKGLAKVEPYRRQHSHIYTNCAFFRELQREHPGAARFVPPAWQSLECDPASAPQTVGSSFSKSIN
QWRQSWILLELSLNVQKWKQPEVTREGLWRAFMRLDAMGESLSRVEGELAYLRLADALVDYRAPLPLTLLVTPTELRALQ
SLVAGEVDSVRDTALRPGVDPVHAPLNEGPAQASTLNRLQQPGIVSDAPLAQLSDADEQAFKMARTARGLRFAIGNRLRQ
LLRSMAAIAVEQGTLQHLDDIHFLYFDELWQLWMGSALPASANKAVIGDRKLRYLDDGLQGAPDWKMDQVGYGFGGGQRL
SPLLRGLTLVPGSAEGAIRRVCSAWCLNKVQPGDIVVVDEVDPAWLPWLVQAAGLVIAQQDPANGAASLAVTYGIPAIWG
ASDVMHSVQDALQGTLDATHGKLAMASDMNNDDVTVQ

Sequences:

>Translated_677_residues
MSIEVLTADIEGGENLQRWAAMGLPIPPSWRISRQVITGNSVQWLTQQLATLAHMFSGDRYWVLQQGPMNPESRRESLLN
LDSDEALAAALQRIFQRAPGPDHVVIQALPKQHAAGVLFTRHPLRQDLPHMVVEGVVGGNSERQRLIFDENDRLVYAPEA
QLPLNQQVGEALFCRLHRQLKDNFKHPQAGEWVFDGEQLWLLQTLPVGSLSVPKEAWARRAGVGLFNQVETPLWYTLAGR
WLKAGFWEPLVESAGWKGLAKVEPYRRQHSHIYTNCAFFRELQREHPGAARFVPPAWQSLECDPASAPQTVGSSFSKSIN
QWRQSWILLELSLNVQKWKQPEVTREGLWRAFMRLDAMGESLSRVEGELAYLRLADALVDYRAPLPLTLLVTPTELRALQ
SLVAGEVDSVRDTALRPGVDPVHAPLNEGPAQASTLNRLQQPGIVSDAPLAQLSDADEQAFKMARTARGLRFAIGNRLRQ
LLRSMAAIAVEQGTLQHLDDIHFLYFDELWQLWMGSALPASANKAVIGDRKLRYLDDGLQGAPDWKMDQVGYGFGGGQRL
SPLLRGLTLVPGSAEGAIRRVCSAWCLNKVQPGDIVVVDEVDPAWLPWLVQAAGLVIAQQDPANGAASLAVTYGIPAIWG
ASDVMHSVQDALQGTLDATHGKLAMASDMNNDDVTVQ
>Mature_676_residues
SIEVLTADIEGGENLQRWAAMGLPIPPSWRISRQVITGNSVQWLTQQLATLAHMFSGDRYWVLQQGPMNPESRRESLLNL
DSDEALAAALQRIFQRAPGPDHVVIQALPKQHAAGVLFTRHPLRQDLPHMVVEGVVGGNSERQRLIFDENDRLVYAPEAQ
LPLNQQVGEALFCRLHRQLKDNFKHPQAGEWVFDGEQLWLLQTLPVGSLSVPKEAWARRAGVGLFNQVETPLWYTLAGRW
LKAGFWEPLVESAGWKGLAKVEPYRRQHSHIYTNCAFFRELQREHPGAARFVPPAWQSLECDPASAPQTVGSSFSKSINQ
WRQSWILLELSLNVQKWKQPEVTREGLWRAFMRLDAMGESLSRVEGELAYLRLADALVDYRAPLPLTLLVTPTELRALQS
LVAGEVDSVRDTALRPGVDPVHAPLNEGPAQASTLNRLQQPGIVSDAPLAQLSDADEQAFKMARTARGLRFAIGNRLRQL
LRSMAAIAVEQGTLQHLDDIHFLYFDELWQLWMGSALPASANKAVIGDRKLRYLDDGLQGAPDWKMDQVGYGFGGGQRLS
PLLRGLTLVPGSAEGAIRRVCSAWCLNKVQPGDIVVVDEVDPAWLPWLVQAAGLVIAQQDPANGAASLAVTYGIPAIWGA
SDVMHSVQDALQGTLDATHGKLAMASDMNNDDVTVQ

Specific function: ESSENTIAL STEP IN GLUCONEOGENESIS WHEN PYRUVATE AND LACTATE ARE USED AS A CARBON SOURCE. [C]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.9.2 [C]

Molecular weight: Translated: 74995; Mature: 74864

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00422 GRANINS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEVLTADIEGGENLQRWAAMGLPIPPSWRISRQVITGNSVQWLTQQLATLAHMFSGDR
CCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCE
YWVLQQGPMNPESRRESLLNLDSDEALAAALQRIFQRAPGPDHVVIQALPKQHAAGVLFT
EEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCEEEE
RHPLRQDLPHMVVEGVVGGNSERQRLIFDENDRLVYAPEAQLPLNQQVGEALFCRLHRQL
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
KDNFKHPQAGEWVFDGEQLWLLQTLPVGSLSVPKEAWARRAGVGLFNQVETPLWYTLAGR
HHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHHH
WLKAGFWEPLVESAGWKGLAKVEPYRRQHSHIYTNCAFFRELQREHPGAARFVPPAWQSL
HHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ECDPASAPQTVGSSFSKSINQWRQSWILLELSLNVQKWKQPEVTREGLWRAFMRLDAMGE
CCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
SLSRVEGELAYLRLADALVDYRAPLPLTLLVTPTELRALQSLVAGEVDSVRDTALRPGVD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCCC
PVHAPLNEGPAQASTLNRLQQPGIVSDAPLAQLSDADEQAFKMARTARGLRFAIGNRLRQ
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
LLRSMAAIAVEQGTLQHLDDIHFLYFDELWQLWMGSALPASANKAVIGDRKLRYLDDGLQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHCCCC
GAPDWKMDQVGYGFGGGQRLSPLLRGLTLVPGSAEGAIRRVCSAWCLNKVQPGDIVVVDE
CCCCCCHHHCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
VDPAWLPWLVQAAGLVIAQQDPANGAASLAVTYGIPAIWGASDVMHSVQDALQGTLDATH
CCCHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
GKLAMASDMNNDDVTVQ
CCEEEECCCCCCCCEEC
>Mature Secondary Structure 
SIEVLTADIEGGENLQRWAAMGLPIPPSWRISRQVITGNSVQWLTQQLATLAHMFSGDR
CEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCE
YWVLQQGPMNPESRRESLLNLDSDEALAAALQRIFQRAPGPDHVVIQALPKQHAAGVLFT
EEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCEEEE
RHPLRQDLPHMVVEGVVGGNSERQRLIFDENDRLVYAPEAQLPLNQQVGEALFCRLHRQL
CCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
KDNFKHPQAGEWVFDGEQLWLLQTLPVGSLSVPKEAWARRAGVGLFNQVETPLWYTLAGR
HHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHHH
WLKAGFWEPLVESAGWKGLAKVEPYRRQHSHIYTNCAFFRELQREHPGAARFVPPAWQSL
HHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ECDPASAPQTVGSSFSKSINQWRQSWILLELSLNVQKWKQPEVTREGLWRAFMRLDAMGE
CCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
SLSRVEGELAYLRLADALVDYRAPLPLTLLVTPTELRALQSLVAGEVDSVRDTALRPGVD
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCCC
PVHAPLNEGPAQASTLNRLQQPGIVSDAPLAQLSDADEQAFKMARTARGLRFAIGNRLRQ
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHH
LLRSMAAIAVEQGTLQHLDDIHFLYFDELWQLWMGSALPASANKAVIGDRKLRYLDDGLQ
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHCCCC
GAPDWKMDQVGYGFGGGQRLSPLLRGLTLVPGSAEGAIRRVCSAWCLNKVQPGDIVVVDE
CCCCCCHHHCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
VDPAWLPWLVQAAGLVIAQQDPANGAASLAVTYGIPAIWGASDVMHSVQDALQGTLDATH
CCCHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
GKLAMASDMNNDDVTVQ
CCEEEECCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg2+; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 10.5 {phosphate}} 0.028 {ATP}} 0.083 {pyruvate}} [C]

Substrates: ATP; H2O; Pyruvate [C]

Specific reaction: ATP + H2O + Pyruvate --> AMP + (2) H+ + Phosphoenolpyruvate + Phosphate [C]

General reaction: Phospho group transfer [C]

Inhibitor: 2-Oxoglutarate; 3-Phosphoglyceraldehyde; 5'-Adenylyl methylen ediphosphonate; ADP; ADP glucose; AMP; ATP; Ca2+; F-; Iodoacetate; Malate; Mg2+; Mn2+; Oxalacetate; PCMB; Phosphoenolpyruvate; Sulfhydryl reagents [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA