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The map label for this gene is moaE [H]

Identifier: 110834140

GI number: 110834140

Start: 1452743

End: 1453177

Strand: Direct

Name: moaE [H]

Synonym: ABO_1279

Alternate gene names: 110834140

Gene position: 1452743-1453177 (Clockwise)

Preceding gene: 110834139

Following gene: 110834142

Centisome position: 46.56

GC content: 58.85

Gene sequence:

>435_bases
GTGGCAGTAACCGGCGCGGCACTTGAGCCGGCGGCACCGACAGACTGGTTGCGCGATCAAGGCCTTAGCGGCGCCGTGGT
GCAATTCAACGGACAGGTGCGCGATGAGCAGGGCAGAGTGGAAGCGCTTCACTTAGAGCATTATCCAGGCATGACAGAAA
CGGTGTTGCGCACCATTGTTGAGCGTGCGGCAGACAAATGGCAACTCAATGGTGTTTGGGTGGTGCACAGAATTGGCACC
ATGGCGGTGGCTGAAGACATTGTGCAGGTAGCGGTCAGCGCCTCCCATCGCCAGGATGCGTTTGCAGCCTGCGCCTTTAT
CATGGACCTGCTAAAAACCCGGGCGCCATTCTGGAAGAAAGAACTTATTAACGGCCATTGGGTTTGGGTCCAGGCCCGCC
AGAGCGATGCCGAGGCCGCCGATGCTTGGCTGTAG

Upstream 100 bases:

>100_bases
TGGTGGCGGTGAATGAGGTGCTGAGCCAAGAACAGACAGCCATCCGTGATGGCGATGTAGTGGCCCTGTTTCCTCCGGTG
ACCGGAGGGTGAAGGTTTGG

Downstream 100 bases:

>100_bases
CGGGCTTTGGGGCGTGAACCATCATAGAACGGGACTCCCCTGGCGCCAAATCGGCAAGAGACCAATCACCGATTTGCCAG
CGAATCAAGCGAAGGGTGGG

Product: molybdenum cofactor biosynthesis protein E

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MAVTGAALEPAAPTDWLRDQGLSGAVVQFNGQVRDEQGRVEALHLEHYPGMTETVLRTIVERAADKWQLNGVWVVHRIGT
MAVAEDIVQVAVSASHRQDAFAACAFIMDLLKTRAPFWKKELINGHWVWVQARQSDAEAADAWL

Sequences:

>Translated_144_residues
MAVTGAALEPAAPTDWLRDQGLSGAVVQFNGQVRDEQGRVEALHLEHYPGMTETVLRTIVERAADKWQLNGVWVVHRIGT
MAVAEDIVQVAVSASHRQDAFAACAFIMDLLKTRAPFWKKELINGHWVWVQARQSDAEAADAWL
>Mature_143_residues
AVTGAALEPAAPTDWLRDQGLSGAVVQFNGQVRDEQGRVEALHLEHYPGMTETVLRTIVERAADKWQLNGVWVVHRIGTM
AVAEDIVQVAVSASHRQDAFAACAFIMDLLKTRAPFWKKELINGHWVWVQARQSDAEAADAWL

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=110, Percent_Identity=34.5454545454545, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1787003, Length=130, Percent_Identity=50.7692307692308, Blast_Score=125, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356259, Length=112, Percent_Identity=39.2857142857143, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 15988; Mature: 15857

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTGAALEPAAPTDWLRDQGLSGAVVQFNGQVRDEQGRVEALHLEHYPGMTETVLRTIV
CCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCEECCCCCEEEEEECCCCCHHHHHHHHHH
ERAADKWQLNGVWVVHRIGTMAVAEDIVQVAVSASHRQDAFAACAFIMDLLKTRAPFWKK
HHHHCCEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
ELINGHWVWVQARQSDAEAADAWL
HHCCCEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
AVTGAALEPAAPTDWLRDQGLSGAVVQFNGQVRDEQGRVEALHLEHYPGMTETVLRTIV
CCCCCCCCCCCCHHHHHHCCCCCEEEEECCCEECCCCCEEEEEECCCCCHHHHHHHHHH
ERAADKWQLNGVWVVHRIGTMAVAEDIVQVAVSASHRQDAFAACAFIMDLLKTRAPFWKK
HHHHCCEECCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHH
ELINGHWVWVQARQSDAEAADAWL
HHCCCEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]