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The map label for this gene is glnS [H]

Identifier: 110834068

GI number: 110834068

Start: 1370536

End: 1372221

Strand: Direct

Name: glnS [H]

Synonym: ABO_1207

Alternate gene names: 110834068

Gene position: 1370536-1372221 (Clockwise)

Preceding gene: 110834064

Following gene: 110834070

Centisome position: 43.93

GC content: 50.95

Gene sequence:

>1686_bases
ATGAGCGAAACGAAAGCGCCAAGCAATTTTATCAGACAGATCATCGACCGTGACCTTGCAGAAGGTAAAAATGACGGCAA
AGTAGTGACCCGTTTTCCACCGGAGCCCAATGGTTATCTGCACATTGGTCATGCTAAATCTATCTGTCTTAACTTTGGTA
TCGCGGAAAGCTATGGCGGCAGCTGTAATTTGCGCTTTGACGATACTAACCCGGAGAAAGAAGAGGACGAGTACATCCAG
TCCATCAAACAGGATGTACAGTGGCTGGGTTATCAGTGGAGCGGACAAGAGCGCTTTGCCAGTAACTACTTTGATCAGCT
TTATGATCTGGCGGTGGGTCTGATCCAAAAAGGGCTAGCGTACGTGGATAGCTTAAGCCCGTCAGAGATTGCTGAATACC
GCGGTAATTTTACCACTCCAGGCAAACCGAGCCCCTATCGTGAGCGTTCGGTGGAGGAGAATTTGACGTTGTTCGAGCAG
ATGCGCAACAACAAACTAGAGGAGGGGGAGGCCGTACTGCGTGCGAAAATTGATATGCAGAGCCCGAATATCAGCCTGCG
TGACCCAATCCTTTACCGTATTCGCAAAAAGACCCACCACCAGACCGGTGATAAGTGGGTGATCTATCCTATGTATGATT
TCACGCATCCGTTGTCTGATGCTATCGAAGGCATTACGCATAGTCTATGCACCCTGGAGTTTGAGGATCACCGCCCCTTT
TATGATTGGGTGGTGGAAAATACGTCAGTGACGACCACTCCGCGTCAGTACGAATTTGCCCGCCTGAATTTGAATTACAC
GCTAACGAGCAAGCGCAAACTCAAGCAATTGGTGGACGAAGGGTATGTAAACGGCTGGAATGACCCGCGCATGCCGACCA
TCTCTGGGCTGCGACGCCGTGGCTATACGCCAAGCTCCATTCGAACTTTCTGTGAATCTGTTGGCGTTAGTCGTGCGGAT
TCTGTGGTTGATATGGCCATGCTTGAAGCGGCGATTCGAGATGACCTTAACCAGCACGCTCCTCGAGCTATGTGTGTGAT
GAACCCGTTGAAACTGGTAATCGAGAATTGGGATGAGGGCAAGGAGGACGTTCTGGTGGCTCCGGTGCACCCTCAGAATG
AGGCCAGAGGTACCCGGCAGGTACCGATGACGCGTGAGTTGTATATTGATCGCGAAGACTTCCGAGAGGAGGCTAATAAG
AAATTCAAACGTTTGGTGTTGGGCGATCGTGTGCGTTTGCGTTACGGCTATGTTGTTCGGGCCACCGATGTTGTGCGTGA
CGATCAAGGTGAAATCGTGGAGGTGCGTTGCACCTATGATCCTGACACCTTAGGCAAAAACCCCGAGAACGCAGAGGGGC
AGGGGAAAATGCGTGGCGTCATTCACTGGGTGAGTGCGGATAAAGCGTTGCCTTGCGAAGTGCGTTTGTACGATCGCCTA
TTCAGTGTCGCCAACCCCAACAAGGAATTAGAAGAAGGGCAGACTTTTCTGTCACACATCAACCCAGACTCTCTGACCGT
TCTGGAGAACTGTTTAGTAGAACCGGGGCTTCGTGGTGCCTTGGCTGAGACTCGTTATCAATTTGAACGGGAGGGGTATT
TTTGTGTGGATCAGGACAGTACCGAGAACCGGTTAGTATTCAATCAGACCGTGGGGTTGCGCGAATCTTGGCCTAAGGAA
GCCTGA

Upstream 100 bases:

>100_bases
AGCCCTGAGTCTTTGACTGTTGGGGGGGCTACAGTACACTAGCGCACCTTCATTTTCACTGTACCCATTTACCGTATCTC
TATCCGGACTGGCCAAGGCA

Downstream 100 bases:

>100_bases
GTTCGGGTGAGGGGCCGCTTTTGAGAAAACCGTACCTAAAAGGGGTGCGGTTTTTTTATGTCCACTCCCCAACGGGATAA
ATTGCGTACAATGAAAGTGT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MSETKAPSNFIRQIIDRDLAEGKNDGKVVTRFPPEPNGYLHIGHAKSICLNFGIAESYGGSCNLRFDDTNPEKEEDEYIQ
SIKQDVQWLGYQWSGQERFASNYFDQLYDLAVGLIQKGLAYVDSLSPSEIAEYRGNFTTPGKPSPYRERSVEENLTLFEQ
MRNNKLEEGEAVLRAKIDMQSPNISLRDPILYRIRKKTHHQTGDKWVIYPMYDFTHPLSDAIEGITHSLCTLEFEDHRPF
YDWVVENTSVTTTPRQYEFARLNLNYTLTSKRKLKQLVDEGYVNGWNDPRMPTISGLRRRGYTPSSIRTFCESVGVSRAD
SVVDMAMLEAAIRDDLNQHAPRAMCVMNPLKLVIENWDEGKEDVLVAPVHPQNEARGTRQVPMTRELYIDREDFREEANK
KFKRLVLGDRVRLRYGYVVRATDVVRDDQGEIVEVRCTYDPDTLGKNPENAEGQGKMRGVIHWVSADKALPCEVRLYDRL
FSVANPNKELEEGQTFLSHINPDSLTVLENCLVEPGLRGALAETRYQFEREGYFCVDQDSTENRLVFNQTVGLRESWPKE
A

Sequences:

>Translated_561_residues
MSETKAPSNFIRQIIDRDLAEGKNDGKVVTRFPPEPNGYLHIGHAKSICLNFGIAESYGGSCNLRFDDTNPEKEEDEYIQ
SIKQDVQWLGYQWSGQERFASNYFDQLYDLAVGLIQKGLAYVDSLSPSEIAEYRGNFTTPGKPSPYRERSVEENLTLFEQ
MRNNKLEEGEAVLRAKIDMQSPNISLRDPILYRIRKKTHHQTGDKWVIYPMYDFTHPLSDAIEGITHSLCTLEFEDHRPF
YDWVVENTSVTTTPRQYEFARLNLNYTLTSKRKLKQLVDEGYVNGWNDPRMPTISGLRRRGYTPSSIRTFCESVGVSRAD
SVVDMAMLEAAIRDDLNQHAPRAMCVMNPLKLVIENWDEGKEDVLVAPVHPQNEARGTRQVPMTRELYIDREDFREEANK
KFKRLVLGDRVRLRYGYVVRATDVVRDDQGEIVEVRCTYDPDTLGKNPENAEGQGKMRGVIHWVSADKALPCEVRLYDRL
FSVANPNKELEEGQTFLSHINPDSLTVLENCLVEPGLRGALAETRYQFEREGYFCVDQDSTENRLVFNQTVGLRESWPKE
A
>Mature_560_residues
SETKAPSNFIRQIIDRDLAEGKNDGKVVTRFPPEPNGYLHIGHAKSICLNFGIAESYGGSCNLRFDDTNPEKEEDEYIQS
IKQDVQWLGYQWSGQERFASNYFDQLYDLAVGLIQKGLAYVDSLSPSEIAEYRGNFTTPGKPSPYRERSVEENLTLFEQM
RNNKLEEGEAVLRAKIDMQSPNISLRDPILYRIRKKTHHQTGDKWVIYPMYDFTHPLSDAIEGITHSLCTLEFEDHRPFY
DWVVENTSVTTTPRQYEFARLNLNYTLTSKRKLKQLVDEGYVNGWNDPRMPTISGLRRRGYTPSSIRTFCESVGVSRADS
VVDMAMLEAAIRDDLNQHAPRAMCVMNPLKLVIENWDEGKEDVLVAPVHPQNEARGTRQVPMTRELYIDREDFREEANKK
FKRLVLGDRVRLRYGYVVRATDVVRDDQGEIVEVRCTYDPDTLGKNPENAEGQGKMRGVIHWVSADKALPCEVRLYDRLF
SVANPNKELEEGQTFLSHINPDSLTVLENCLVEPGLRGALAETRYQFEREGYFCVDQDSTENRLVFNQTVGLRESWPKEA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=533, Percent_Identity=47.2795497185741, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI62241042, Length=523, Percent_Identity=33.2695984703633, Blast_Score=257, Evalue=2e-68,
Organism=Escherichia coli, GI1786895, Length=561, Percent_Identity=62.7450980392157, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=309, Percent_Identity=24.2718446601942, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=536, Percent_Identity=45.8955223880597, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17511007, Length=523, Percent_Identity=32.5047801147228, Blast_Score=247, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6324742, Length=571, Percent_Identity=39.2294220665499, Blast_Score=391, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321192, Length=524, Percent_Identity=35.1145038167939, Blast_Score=300, Evalue=6e-82,
Organism=Drosophila melanogaster, GI17864488, Length=555, Percent_Identity=43.7837837837838, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24649466, Length=523, Percent_Identity=33.8432122370937, Blast_Score=260, Evalue=2e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64497; Mature: 64366

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETKAPSNFIRQIIDRDLAEGKNDGKVVTRFPPEPNGYLHIGHAKSICLNFGIAESYGG
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHEECCCHHCCCC
SCNLRFDDTNPEKEEDEYIQSIKQDVQWLGYQWSGQERFASNYFDQLYDLAVGLIQKGLA
EEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YVDSLSPSEIAEYRGNFTTPGKPSPYRERSVEENLTLFEQMRNNKLEEGEAVLRAKIDMQ
HHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECC
SPNISLRDPILYRIRKKTHHQTGDKWVIYPMYDFTHPLSDAIEGITHSLCTLEFEDHRPF
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHCCCCHHHHHHHHHHHHEEEEECCCCCH
YDWVVENTSVTTTPRQYEFARLNLNYTLTSKRKLKQLVDEGYVNGWNDPRMPTISGLRRR
HHHEEECCEEECCCCCEEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GYTPSSIRTFCESVGVSRADSVVDMAMLEAAIRDDLNQHAPRAMCVMNPLKLVIENWDEG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
KEDVLVAPVHPQNEARGTRQVPMTRELYIDREDFREEANKKFKRLVLGDRVRLRYGYVVR
CCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
ATDVVRDDQGEIVEVRCTYDPDTLGKNPENAEGQGKMRGVIHWVSADKALPCEVRLYDRL
EEHHEECCCCCEEEEEECCCCHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
FSVANPNKELEEGQTFLSHINPDSLTVLENCLVEPGLRGALAETRYQFEREGYFCVDQDS
HHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCC
TENRLVFNQTVGLRESWPKEA
CCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SETKAPSNFIRQIIDRDLAEGKNDGKVVTRFPPEPNGYLHIGHAKSICLNFGIAESYGG
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHEECCCHHCCCC
SCNLRFDDTNPEKEEDEYIQSIKQDVQWLGYQWSGQERFASNYFDQLYDLAVGLIQKGLA
EEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YVDSLSPSEIAEYRGNFTTPGKPSPYRERSVEENLTLFEQMRNNKLEEGEAVLRAKIDMQ
HHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECC
SPNISLRDPILYRIRKKTHHQTGDKWVIYPMYDFTHPLSDAIEGITHSLCTLEFEDHRPF
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHCCCCHHHHHHHHHHHHEEEEECCCCCH
YDWVVENTSVTTTPRQYEFARLNLNYTLTSKRKLKQLVDEGYVNGWNDPRMPTISGLRRR
HHHEEECCEEECCCCCEEEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GYTPSSIRTFCESVGVSRADSVVDMAMLEAAIRDDLNQHAPRAMCVMNPLKLVIENWDEG
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
KEDVLVAPVHPQNEARGTRQVPMTRELYIDREDFREEANKKFKRLVLGDRVRLRYGYVVR
CCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
ATDVVRDDQGEIVEVRCTYDPDTLGKNPENAEGQGKMRGVIHWVSADKALPCEVRLYDRL
EEHHEECCCCCEEEEEECCCCHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
FSVANPNKELEEGQTFLSHINPDSLTVLENCLVEPGLRGALAETRYQFEREGYFCVDQDS
HHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCC
TENRLVFNQTVGLRESWPKEA
CCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA