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The map label for this gene is tatD [C]

Identifier: 110833938

GI number: 110833938

Start: 1218311

End: 1219132

Strand: Direct

Name: tatD [C]

Synonym: ABO_1077

Alternate gene names: 110833938

Gene position: 1218311-1219132 (Clockwise)

Preceding gene: 110833937

Following gene: 110833939

Centisome position: 39.05

GC content: 55.35

Gene sequence:

>822_bases
ATGCCTGCGTTTTTAACGTTGGAGCTTGTTGTGATTGCTACCTCTTTTGTGGATTCCCATTGTCATTTAGATCGTCTGAA
TCTTGACGCCCATGATGGCGACTTCGCGGCGATGATGGCGGCCACCGCGCAGGCTAGGATCAGCCACATGCTGTGCATCG
GTGTGGATCTAGAAACCTTTCCGCAAGTGCAGGCGCTGGCTGAACAATATGACAATGTTTTTGCCAGCGTCGGGGTGCAT
CCACTTTACAAGGAATCCCGTGAGCCCGTTGTAGAGGAGCTGATTGAGCGTGGGGCCCACCCCAAGGTTGTCGCTATTGG
CGAAACCGGGCTGGATTACTTCTATGCAAAGGAAGAGCGAGAGTGGCAGCAGCGCTATTTTATTGCCCATATTCAGGCTG
CTCGTGAAACCGGCCTGCCTTTGGTTGTGCACACGCGCGGCGCCAAGGAGGATACCTTGGCGCTGTTGCGCGAGCACGGT
AGGGGGGAAGTTCGCGGCGTGCTCCACTGCTTCACTGAAGACCTGGACATGGCCCGACAGGCCATAGAGCTGGGTTTCTA
CATTTCCATTTCTGGGATTGTCACGTTTCGCAATGCGCAGGCCCTGCGGGAGACCGTGAGGCAGTTACCTCTGGAGCGTT
TATTGATCGAAACCGATTCCCCCTGGCTCGCTCCAGTTCCTTTTCGTGGCAAGCCCAATGAGCCGCGCTATGTGGTTCAG
GTGGCTGAATGTGTGGCAGCACTGCAGGGGATCAGTGTGGATGCTCTGGCGGCGGCCACCACGAATAACTTCTTTTCTCT
GTTCAACAAGGCACAAGCATGA

Upstream 100 bases:

>100_bases
GCCTCTTTTTTAGGACGCGGCCTTCTGTATTTCAGATGCGATCATTTTAGCCGGTGCTGTGTGTGCCGCGTGGTGTGTGC
TGGGCGCTCCCTACGCTACA

Downstream 100 bases:

>100_bases
ACCTGTATGCAATGCTGGCGCTGGCAGCGCTAGGTGGTGGTGTAGTGGCAGCGTTGCTTGTGGCGTTGCTGGAGCGGCGC
CGAGCGGCTGCGCGTGAAGC

Product: TatD family deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPAFLTLELVVIATSFVDSHCHLDRLNLDAHDGDFAAMMAATAQARISHMLCIGVDLETFPQVQALAEQYDNVFASVGVH
PLYKESREPVVEELIERGAHPKVVAIGETGLDYFYAKEEREWQQRYFIAHIQAARETGLPLVVHTRGAKEDTLALLREHG
RGEVRGVLHCFTEDLDMARQAIELGFYISISGIVTFRNAQALRETVRQLPLERLLIETDSPWLAPVPFRGKPNEPRYVVQ
VAECVAALQGISVDALAAATTNNFFSLFNKAQA

Sequences:

>Translated_273_residues
MPAFLTLELVVIATSFVDSHCHLDRLNLDAHDGDFAAMMAATAQARISHMLCIGVDLETFPQVQALAEQYDNVFASVGVH
PLYKESREPVVEELIERGAHPKVVAIGETGLDYFYAKEEREWQQRYFIAHIQAARETGLPLVVHTRGAKEDTLALLREHG
RGEVRGVLHCFTEDLDMARQAIELGFYISISGIVTFRNAQALRETVRQLPLERLLIETDSPWLAPVPFRGKPNEPRYVVQ
VAECVAALQGISVDALAAATTNNFFSLFNKAQA
>Mature_272_residues
PAFLTLELVVIATSFVDSHCHLDRLNLDAHDGDFAAMMAATAQARISHMLCIGVDLETFPQVQALAEQYDNVFASVGVHP
LYKESREPVVEELIERGAHPKVVAIGETGLDYFYAKEEREWQQRYFIAHIQAARETGLPLVVHTRGAKEDTLALLREHGR
GEVRGVLHCFTEDLDMARQAIELGFYISISGIVTFRNAQALRETVRQLPLERLLIETDSPWLAPVPFRGKPNEPRYVVQV
AECVAALQGISVDALAAATTNNFFSLFNKAQA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=30.8823529411765, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=30.8823529411765, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI226061853, Length=278, Percent_Identity=30.5755395683453, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI226061614, Length=263, Percent_Identity=30.7984790874525, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI225903424, Length=224, Percent_Identity=29.9107142857143, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI14042943, Length=271, Percent_Identity=25.830258302583, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI226061595, Length=238, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=27.4193548387097, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=49.8039215686275, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=32.6848249027237, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI48994985, Length=240, Percent_Identity=35.4166666666667, Blast_Score=131, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=262, Percent_Identity=27.4809160305344, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=26.0377358490566, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=317, Percent_Identity=26.1829652996845, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=292, Percent_Identity=23.972602739726, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221330018, Length=278, Percent_Identity=27.6978417266187, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24586117, Length=278, Percent_Identity=27.6978417266187, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24648690, Length=269, Percent_Identity=26.3940520446097, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30400; Mature: 30269

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFLTLELVVIATSFVDSHCHLDRLNLDAHDGDFAAMMAATAQARISHMLCIGVDLETF
CCCEEHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHH
PQVQALAEQYDNVFASVGVHPLYKESREPVVEELIERGAHPKVVAIGETGLDYFYAKEER
HHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEECHHH
EWQQRYFIAHIQAARETGLPLVVHTRGAKEDTLALLREHGRGEVRGVLHCFTEDLDMARQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIELGFYISISGIVTFRNAQALRETVRQLPLERLLIETDSPWLAPVPFRGKPNEPRYVVQ
HHHHCEEEEEEEEEEECCHHHHHHHHHHCCHHHEEEECCCCCEECCCCCCCCCCCHHHHH
VAECVAALQGISVDALAAATTNNFFSLFNKAQA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAFLTLELVVIATSFVDSHCHLDRLNLDAHDGDFAAMMAATAQARISHMLCIGVDLETF
CCEEHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHH
PQVQALAEQYDNVFASVGVHPLYKESREPVVEELIERGAHPKVVAIGETGLDYFYAKEER
HHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHCCCCCCEEEECCCCCCCEEECHHH
EWQQRYFIAHIQAARETGLPLVVHTRGAKEDTLALLREHGRGEVRGVLHCFTEDLDMARQ
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AIELGFYISISGIVTFRNAQALRETVRQLPLERLLIETDSPWLAPVPFRGKPNEPRYVVQ
HHHHCEEEEEEEEEEECCHHHHHHHHHHCCHHHEEEECCCCCEECCCCCCCCCCCHHHHH
VAECVAALQGISVDALAAATTNNFFSLFNKAQA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]