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The map label for this gene is pepN [H]

Identifier: 110833859

GI number: 110833859

Start: 1131045

End: 1133681

Strand: Direct

Name: pepN [H]

Synonym: ABO_0998

Alternate gene names: 110833859

Gene position: 1131045-1133681 (Clockwise)

Preceding gene: 110833858

Following gene: 110833860

Centisome position: 36.25

GC content: 55.25

Gene sequence:

>2637_bases
ATGGAAAGTGCAGAAATGGTGAAATTCACCCATTTGGCGGACTATCAGCCCCCAGCCTATCTAGTCGATAGAGTGGCTCT
GGATGTGGATATTCGGGATGGGGTGACCACTGTGACCAGCAGTCTATCGCTGCGCCGTAATCCGGCTGCTGCTGATTCCA
CGACAATGACCTTCAATGGCGAAGGGCTCACCTTACGCACTTTGGCGCTGGATGATGTGGTGCTCAATAGTGCTCGCTAT
CAGTATGAAGATAACCTGCTGACCGTGCGGGGCTTGCCAGATACCTGCACGTTAACGTCCGTGGTGGATATTGATCCAGA
AAACAATACCGCCCTGGAAGGGTTATACCAGTCCAATGGCATGGTCTGCACCCAGTGTGAGGCGGAAGGCTTTCGGCGTA
TTACCTTTTTCCCGGACCGCCCTGACGTATTGGCCCGCTTTACGACCACGGTACGTGCTGACAAGGCCCGCTATCCGCTG
TTGCTGTCTAACGGTAATCCGGTGGCTTCGGGCGATGAAAAGAGTCATGGAGAAGAGGGCGCTCGTCACTGGGTGACTTG
GGAAGACCCTTTTCCGAAACCATGCTATCTGTTCGCTTTGGTGGCGGGAGATCTAGCCTGCCTGGAGGATACGTTTGTCA
CTGTATCGGGCCGTAAGGTGGCGTTACGCCTCTATGCTGAGCATCGTGATCTGGACAAGCTGGACCATGCCATGGCGTCG
TTGAAAAATGCCATGCGCTGGGACGAACAAACCTACGGTCGCGAATACGATCTGGATATCTACATGATTGTGGCGGTAAG
CCACTTCAATATGGGGGCCATGGAAAATAAGGGCCTTAATATCTTTAACACCTCCTGTGTGCTGGCGCATCCCGCTACGA
CCACCGACGCCGGGTTCCAACGGGTGGAATCTGTAGTGGCCCATGAGTACTTTCATAACTGGTCTGGAAACCGGGTGACC
TGCCGTGACTGGTTTCAATTGAGTCTTAAGGAAGGTTTCACGGTATTTCGTGACCAGGAATTCTCGGCGGACATGCATTC
CGCCGCAGTGAAACGCGTTGAAGATGTGGATTTCCTGGTCAACCATCAATTCCCGGAAGACCAAGGCCCCATGGCCCATG
CTGTTCGCCCTGAGAAATACCAGAAAATTGACAATTTCTACACCCTAACCATTTATGAAAAAGGCGCAGAAATTGTTCGT
ATGCAGTATCACCTGCTGGGGGCAGAGAATTTCCGCAAGGCCACGGATCATTATTTCGAGACCAATGATGGCAAGGCGGT
AACTTGCGATGATTTCGTGGCCAGCATGGAAACCGTTTCCGGCTACGATTTGAGCCAGTTTAAATGTTGGTACAGCCAGG
CCGGCACGCCGATACTGACGGTTACCGATGAATACCGGGACGGGCAGTATCACCTTAGGTTCCGTCAGCATACGCCCGCC
ACTCCCGGACAGGAGCAGAAACAGCCCTTGGTTATCCCTATTCGTCTGGCGTTGCTTGATGAGCAGGGCGCTCCCTGTGC
GTTGGATGCTGGAGGCAACGGTGCGGCTGAGGGGGAGCAGGTGGTTATCATGGACCAGGCTGAGCAAACCGTGTCGTTTA
ATGTGCCTGCTGGGGTGACACCTTCTCTGCTGCGTGGGTTCTCAGCGCCAGTGGTGCTCGATTATGACTACTCCGTTGAT
CAATTGGCGCGACTGTTGGCCTACGACAGTGACGGCTATTGCCGTTGGAATGCCGCCCAGCGCCTGTACTTTGCGGCACT
GGATCGGTTAGTGACCGAAACCGATGAGGCGGATGCAGAAGCCGCAGCGCTGGTGCCGGTGCTGGAGCAAGTGATTGCCC
GTAGTGATGAAGATCCGGCCCAAGCGGCATTGCTGCTTTCATTACCTGGCGAGGTAGCGTTGGGAGACCGGCATAAGCCG
CTGAACCCGGCCTCCATTCATCGCGCGCACAGTGCCATGAAGAAAGCGTTAGGAAAGGCGTTGCAGTCGCACTGGTTGTC
TCTGTCCGAGAACCTGCTGGCTACGGAACTGAGTATGGATGGGCGGGCGATGGGGCGGCGGCAGTTACGTAATCTGGCGT
TGGATTTTTTAGCAGCAGGAGAGCACCCGGAAGCAGGTCGGATAGCCGTGGAGTTATTTGAGCTGCCACTGTGTATGAGT
GAAGAGCTTGGCGCATTGCGAGCGCTGGTACACCATGGTTTGCCCGGTGCCGATCAGGCACTGATGCAATTTGCGGATCG
CTGGCAGGATGAGGCGTTGGTTATGGATCAGTGGTTTGCTGTCCAGGCATCCGTGCCGGGGGCTCACACCGTCGATCAGG
TAAACCGCCTGCTTGAACACCCTGCTTTTGACTGGAAGACACCGAATCGAGTGCGAGCGCTAGTGGGCACGTTCACGAAC
GCAAATCCGTCGGCATTTCATGCGGAAAATGGGCAAGGGTATCAACTATTTTCGGCTGCCTTGTCTCGCTTGGACGCCAT
CAACCCGCAGGTTGCGGCCCGTTTGGCCAATGGGGCTTCTCGTTTGCCTGTATTGGAACCGGGCCGGAAGGCTTTATTGG
CGGAGCACCTTGCGGGTGTGCAAAAGACAGCGTCCGATAACGTGGCGGAGGTGCTTGGGCGGATCCTGTCATCCTGA

Upstream 100 bases:

>100_bases
CCGCAAGCCGGGGTGTTGTTGTTTTCGTGGATATGATGTTTGAGCGGTGCTAGGCCGGATTGGCATGGCCGCCAGACTAA
CCTTTTTGAGGAGTAGGGTT

Downstream 100 bases:

>100_bases
TCTTCTATGGGGGTATAGAAAGAAAAAGGACGATGACTGGTTAGTCGTCAATAATAGAGCACACAGGGGATTTATTTTTT
TTTCTGGTGTGTAAGAATTA

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 878; Mature: 878

Protein sequence:

>878_residues
MESAEMVKFTHLADYQPPAYLVDRVALDVDIRDGVTTVTSSLSLRRNPAAADSTTMTFNGEGLTLRTLALDDVVLNSARY
QYEDNLLTVRGLPDTCTLTSVVDIDPENNTALEGLYQSNGMVCTQCEAEGFRRITFFPDRPDVLARFTTTVRADKARYPL
LLSNGNPVASGDEKSHGEEGARHWVTWEDPFPKPCYLFALVAGDLACLEDTFVTVSGRKVALRLYAEHRDLDKLDHAMAS
LKNAMRWDEQTYGREYDLDIYMIVAVSHFNMGAMENKGLNIFNTSCVLAHPATTTDAGFQRVESVVAHEYFHNWSGNRVT
CRDWFQLSLKEGFTVFRDQEFSADMHSAAVKRVEDVDFLVNHQFPEDQGPMAHAVRPEKYQKIDNFYTLTIYEKGAEIVR
MQYHLLGAENFRKATDHYFETNDGKAVTCDDFVASMETVSGYDLSQFKCWYSQAGTPILTVTDEYRDGQYHLRFRQHTPA
TPGQEQKQPLVIPIRLALLDEQGAPCALDAGGNGAAEGEQVVIMDQAEQTVSFNVPAGVTPSLLRGFSAPVVLDYDYSVD
QLARLLAYDSDGYCRWNAAQRLYFAALDRLVTETDEADAEAAALVPVLEQVIARSDEDPAQAALLLSLPGEVALGDRHKP
LNPASIHRAHSAMKKALGKALQSHWLSLSENLLATELSMDGRAMGRRQLRNLALDFLAAGEHPEAGRIAVELFELPLCMS
EELGALRALVHHGLPGADQALMQFADRWQDEALVMDQWFAVQASVPGAHTVDQVNRLLEHPAFDWKTPNRVRALVGTFTN
ANPSAFHAENGQGYQLFSAALSRLDAINPQVAARLANGASRLPVLEPGRKALLAEHLAGVQKTASDNVAEVLGRILSS

Sequences:

>Translated_878_residues
MESAEMVKFTHLADYQPPAYLVDRVALDVDIRDGVTTVTSSLSLRRNPAAADSTTMTFNGEGLTLRTLALDDVVLNSARY
QYEDNLLTVRGLPDTCTLTSVVDIDPENNTALEGLYQSNGMVCTQCEAEGFRRITFFPDRPDVLARFTTTVRADKARYPL
LLSNGNPVASGDEKSHGEEGARHWVTWEDPFPKPCYLFALVAGDLACLEDTFVTVSGRKVALRLYAEHRDLDKLDHAMAS
LKNAMRWDEQTYGREYDLDIYMIVAVSHFNMGAMENKGLNIFNTSCVLAHPATTTDAGFQRVESVVAHEYFHNWSGNRVT
CRDWFQLSLKEGFTVFRDQEFSADMHSAAVKRVEDVDFLVNHQFPEDQGPMAHAVRPEKYQKIDNFYTLTIYEKGAEIVR
MQYHLLGAENFRKATDHYFETNDGKAVTCDDFVASMETVSGYDLSQFKCWYSQAGTPILTVTDEYRDGQYHLRFRQHTPA
TPGQEQKQPLVIPIRLALLDEQGAPCALDAGGNGAAEGEQVVIMDQAEQTVSFNVPAGVTPSLLRGFSAPVVLDYDYSVD
QLARLLAYDSDGYCRWNAAQRLYFAALDRLVTETDEADAEAAALVPVLEQVIARSDEDPAQAALLLSLPGEVALGDRHKP
LNPASIHRAHSAMKKALGKALQSHWLSLSENLLATELSMDGRAMGRRQLRNLALDFLAAGEHPEAGRIAVELFELPLCMS
EELGALRALVHHGLPGADQALMQFADRWQDEALVMDQWFAVQASVPGAHTVDQVNRLLEHPAFDWKTPNRVRALVGTFTN
ANPSAFHAENGQGYQLFSAALSRLDAINPQVAARLANGASRLPVLEPGRKALLAEHLAGVQKTASDNVAEVLGRILSS
>Mature_878_residues
MESAEMVKFTHLADYQPPAYLVDRVALDVDIRDGVTTVTSSLSLRRNPAAADSTTMTFNGEGLTLRTLALDDVVLNSARY
QYEDNLLTVRGLPDTCTLTSVVDIDPENNTALEGLYQSNGMVCTQCEAEGFRRITFFPDRPDVLARFTTTVRADKARYPL
LLSNGNPVASGDEKSHGEEGARHWVTWEDPFPKPCYLFALVAGDLACLEDTFVTVSGRKVALRLYAEHRDLDKLDHAMAS
LKNAMRWDEQTYGREYDLDIYMIVAVSHFNMGAMENKGLNIFNTSCVLAHPATTTDAGFQRVESVVAHEYFHNWSGNRVT
CRDWFQLSLKEGFTVFRDQEFSADMHSAAVKRVEDVDFLVNHQFPEDQGPMAHAVRPEKYQKIDNFYTLTIYEKGAEIVR
MQYHLLGAENFRKATDHYFETNDGKAVTCDDFVASMETVSGYDLSQFKCWYSQAGTPILTVTDEYRDGQYHLRFRQHTPA
TPGQEQKQPLVIPIRLALLDEQGAPCALDAGGNGAAEGEQVVIMDQAEQTVSFNVPAGVTPSLLRGFSAPVVLDYDYSVD
QLARLLAYDSDGYCRWNAAQRLYFAALDRLVTETDEADAEAAALVPVLEQVIARSDEDPAQAALLLSLPGEVALGDRHKP
LNPASIHRAHSAMKKALGKALQSHWLSLSENLLATELSMDGRAMGRRQLRNLALDFLAAGEHPEAGRIAVELFELPLCMS
EELGALRALVHHGLPGADQALMQFADRWQDEALVMDQWFAVQASVPGAHTVDQVNRLLEHPAFDWKTPNRVRALVGTFTN
ANPSAFHAENGQGYQLFSAALSRLDAINPQVAARLANGASRLPVLEPGRKALLAEHLAGVQKTASDNVAEVLGRILSS

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=421, Percent_Identity=27.3159144893112, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI132814467, Length=369, Percent_Identity=28.4552845528455, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI310123622, Length=363, Percent_Identity=26.9972451790634, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310133497, Length=364, Percent_Identity=26.9230769230769, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI61742777, Length=277, Percent_Identity=25.6317689530686, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI61742775, Length=277, Percent_Identity=25.6317689530686, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI194306629, Length=307, Percent_Identity=27.6872964169381, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI11641261, Length=307, Percent_Identity=27.6872964169381, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI94818901, Length=321, Percent_Identity=23.98753894081, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI94818891, Length=321, Percent_Identity=23.98753894081, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI194239713, Length=360, Percent_Identity=24.7222222222222, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI4505029, Length=345, Percent_Identity=25.5072463768116, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI7019561, Length=412, Percent_Identity=26.6990291262136, Blast_Score=74, Evalue=9e-13,
Organism=Homo sapiens, GI157266300, Length=335, Percent_Identity=26.5671641791045, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787163, Length=874, Percent_Identity=45.6521739130435, Blast_Score=733, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193206928, Length=443, Percent_Identity=26.1851015801354, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193206926, Length=443, Percent_Identity=26.1851015801354, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17569225, Length=288, Percent_Identity=28.8194444444444, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71989076, Length=446, Percent_Identity=26.6816143497758, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71989071, Length=446, Percent_Identity=26.6816143497758, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17569221, Length=298, Percent_Identity=26.510067114094, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17565628, Length=451, Percent_Identity=25.2771618625277, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533276, Length=381, Percent_Identity=25.7217847769029, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533278, Length=381, Percent_Identity=25.7217847769029, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI133903840, Length=458, Percent_Identity=23.7991266375546, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17544504, Length=348, Percent_Identity=23.8505747126437, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984353, Length=494, Percent_Identity=24.6963562753036, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984339, Length=495, Percent_Identity=25.0505050505051, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=401, Percent_Identity=26.9326683291771, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321837, Length=402, Percent_Identity=26.1194029850746, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646514, Length=413, Percent_Identity=30.0242130750605, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646516, Length=370, Percent_Identity=30.8108108108108, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24646518, Length=370, Percent_Identity=30.8108108108108, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI221379089, Length=356, Percent_Identity=27.8089887640449, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24651025, Length=459, Percent_Identity=25.7080610021786, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24651023, Length=459, Percent_Identity=25.7080610021786, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24651021, Length=459, Percent_Identity=25.7080610021786, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24655257, Length=484, Percent_Identity=26.2396694214876, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655274, Length=508, Percent_Identity=25.5905511811024, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655260, Length=508, Percent_Identity=25.5905511811024, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655265, Length=508, Percent_Identity=25.5905511811024, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655268, Length=508, Percent_Identity=25.5905511811024, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655252, Length=484, Percent_Identity=25.8264462809917, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21358341, Length=373, Percent_Identity=25.7372654155496, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646512, Length=370, Percent_Identity=25.6756756756757, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24646510, Length=370, Percent_Identity=25.6756756756757, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24650973, Length=375, Percent_Identity=27.4666666666667, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI45550850, Length=375, Percent_Identity=27.4666666666667, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24651016, Length=281, Percent_Identity=28.4697508896797, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI161078673, Length=455, Percent_Identity=25.2747252747253, Blast_Score=81, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571901, Length=455, Percent_Identity=25.2747252747253, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648786, Length=395, Percent_Identity=24.8101265822785, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648790, Length=218, Percent_Identity=29.8165137614679, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571792, Length=382, Percent_Identity=24.0837696335079, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 97178; Mature: 97178

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAEMVKFTHLADYQPPAYLVDRVALDVDIRDGVTTVTSSLSLRRNPAAADSTTMTFNG
CCCCCEEEEEHHCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECC
EGLTLRTLALDDVVLNSARYQYEDNLLTVRGLPDTCTLTSVVDIDPENNTALEGLYQSNG
CCEEEEEEEHHHHHHHCCCEEECCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCC
MVCTQCEAEGFRRITFFPDRPDVLARFTTTVRADKARYPLLLSNGNPVASGDEKSHGEEG
EEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCC
ARHWVTWEDPFPKPCYLFALVAGDLACLEDTFVTVSGRKVALRLYAEHRDLDKLDHAMAS
CCEEEEECCCCCCHHHHHHHHHCCHHHCCCCEEEECCCEEEEEEEHHHCCHHHHHHHHHH
LKNAMRWDEQTYGREYDLDIYMIVAVSHFNMGAMENKGLNIFNTSCVLAHPATTTDAGFQ
HHHHHHCCHHHCCCEECCCEEEEEEEECCCCCCCCCCCCEEEECCEEEECCCCCCHHHHH
RVESVVAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDQEFSADMHSAAVKRVEDVDFLV
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHEE
NHQFPEDQGPMAHAVRPEKYQKIDNFYTLTIYEKGAEIVRMQYHLLGAENFRKATDHYFE
CCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEECCCCEEEHHHHHHCCHHHHHHHHCCEE
TNDGKAVTCDDFVASMETVSGYDLSQFKCWYSQAGTPILTVTDEYRDGQYHLRFRQHTPA
CCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCC
TPGQEQKQPLVIPIRLALLDEQGAPCALDAGGNGAAEGEQVVIMDQAEQTVSFNVPAGVT
CCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCC
PSLLRGFSAPVVLDYDYSVDQLARLLAYDSDGYCRWNAAQRLYFAALDRLVTETDEADAE
HHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHH
AAALVPVLEQVIARSDEDPAQAALLLSLPGEVALGDRHKPLNPASIHRAHSAMKKALGKA
HHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LQSHWLSLSENLLATELSMDGRAMGRRQLRNLALDFLAAGEHPEAGRIAVELFELPLCMS
HHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHH
EELGALRALVHHGLPGADQALMQFADRWQDEALVMDQWFAVQASVPGAHTVDQVNRLLEH
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHC
PAFDWKTPNRVRALVGTFTNANPSAFHAENGQGYQLFSAALSRLDAINPQVAARLANGAS
CCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCC
RLPVLEPGRKALLAEHLAGVQKTASDNVAEVLGRILSS
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MESAEMVKFTHLADYQPPAYLVDRVALDVDIRDGVTTVTSSLSLRRNPAAADSTTMTFNG
CCCCCEEEEEHHCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEECC
EGLTLRTLALDDVVLNSARYQYEDNLLTVRGLPDTCTLTSVVDIDPENNTALEGLYQSNG
CCEEEEEEEHHHHHHHCCCEEECCCEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHCCC
MVCTQCEAEGFRRITFFPDRPDVLARFTTTVRADKARYPLLLSNGNPVASGDEKSHGEEG
EEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCC
ARHWVTWEDPFPKPCYLFALVAGDLACLEDTFVTVSGRKVALRLYAEHRDLDKLDHAMAS
CCEEEEECCCCCCHHHHHHHHHCCHHHCCCCEEEECCCEEEEEEEHHHCCHHHHHHHHHH
LKNAMRWDEQTYGREYDLDIYMIVAVSHFNMGAMENKGLNIFNTSCVLAHPATTTDAGFQ
HHHHHHCCHHHCCCEECCCEEEEEEEECCCCCCCCCCCCEEEECCEEEECCCCCCHHHHH
RVESVVAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDQEFSADMHSAAVKRVEDVDFLV
HHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHEE
NHQFPEDQGPMAHAVRPEKYQKIDNFYTLTIYEKGAEIVRMQYHLLGAENFRKATDHYFE
CCCCCCCCCCCCCCCCCHHHHHHCCEEEEEEEECCCCEEEHHHHHHCCHHHHHHHHCCEE
TNDGKAVTCDDFVASMETVSGYDLSQFKCWYSQAGTPILTVTDEYRDGQYHLRFRQHTPA
CCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCC
TPGQEQKQPLVIPIRLALLDEQGAPCALDAGGNGAAEGEQVVIMDQAEQTVSFNVPAGVT
CCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCC
PSLLRGFSAPVVLDYDYSVDQLARLLAYDSDGYCRWNAAQRLYFAALDRLVTETDEADAE
HHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHH
AAALVPVLEQVIARSDEDPAQAALLLSLPGEVALGDRHKPLNPASIHRAHSAMKKALGKA
HHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LQSHWLSLSENLLATELSMDGRAMGRRQLRNLALDFLAAGEHPEAGRIAVELFELPLCMS
HHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHH
EELGALRALVHHGLPGADQALMQFADRWQDEALVMDQWFAVQASVPGAHTVDQVNRLLEH
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHC
PAFDWKTPNRVRALVGTFTNANPSAFHAENGQGYQLFSAALSRLDAINPQVAARLANGAS
CCCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCC
RLPVLEPGRKALLAEHLAGVQKTASDNVAEVLGRILSS
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]