Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 110833818

GI number: 110833818

Start: 1077270

End: 1078478

Strand: Direct

Name: yngJ [H]

Synonym: ABO_0957

Alternate gene names: 110833818

Gene position: 1077270-1078478 (Clockwise)

Preceding gene: 110833817

Following gene: 110833819

Centisome position: 34.53

GC content: 53.6

Gene sequence:

>1209_bases
ATGGATTTTCAGTACACAGAAAAAATGCAGACATTGATCACTCAGGTGCGTGATTTTATTAACAACGAAATCCGCCCGGC
GGAAAACGTGTATTACGAGCAGCTGGCAAAGAGCCCGTGGGAAACGCCGCCGATCATGGATGAACTGAAAGAAAAGGCCC
GAGCTAAAGGGTTATGGAACCTGTTTTTGCCTACAGAGTACGCAGAGTACAGCGCAGGCTTAAGTAACCTGGAGTATGCG
CCGCTGGCAGAAGAAATGGGGCGCTGTCGTATTGCATCCGAAGCGTTTAACTGTGCTGCTCCGGATACTGGCAATATGGA
GGTGCTGGCAAAATACGGCAACGATGCTCAGAAAGAACAGTGGTTGTTGCCGTTGTTGGAAGGCCGTATTCGTAGTGCCT
TCGCCATGACCGAGCCGCAAGTGGCGTCCTCTGACGCGACTAATATCGAAACGCGTATAACGGAAGATGGCGACGATTAC
ATCATCAACGGCCGTAAGTTTTATATCAGCGGCGCCATGCGAAAAACCTGCGAAATTATGATTGTCATGGGCAAGAGCAG
CCCGGATAACCCCAACCGCCACCAGCAGCAATCCCAGATTTTGGTGCCTACCAATACCCCCGGGGTCAACATTGTTCGCC
CGATGCAGGTATTTGGTTACAACGATGCACCCGAAGGCCATGCCGACGTTATTTTCGACAATGTGCGTGTGCCCAAGGCC
AATATAATTCTCGGTGAAGGGCGGGGTTTCGAAATCGCTCAGGGGCGCCTGGGTCCGGGCCGGATTCACCACTGCATGCG
TATGATCGGCGCGGCTCAGGAGGCGTTTGAGATGATGTGCAAGCGGGTAAACCAGCGTGAAGTGTTCGGTGCGCCCATGA
GCAAGCAGGGCTCGGTGCGCGAAGATATCGCCAAATCTTACTGCGAGATTGAGCAGGCACGGTTGCTGACGCTGAAAGCC
GCAGACGCCATGGATCGCTCAGGTAACAAAGACGCGAAGGATTTGATCGCTATGATCAAGGTGGTTGCGCCTAATATGGC
GTTAAATGTTATCGACCGGGCGATTCAGATCCACGGTGCCGTGGGCTTGAGCCAGGATACGCCGTTGGTTCACTTCTTTA
GCTACGCGCGCACGCTGCGTCTGGCCGATGGCCCGGATCAGGTGCACATGATGCAGTTGGGCCGGAACATGGCTAAACAA
TTCGCCTGA

Upstream 100 bases:

>100_bases
CTACTAATTTTCGTGCTTTGTGCTCCAACCTTGTACGCGCTGCATCGCATTTAACGCAGCCACGAGACTGCAGGAGCAAA
CGGGTAATAGGGAGAGCGTC

Downstream 100 bases:

>100_bases
TTTCAGGTGTGGCCCGCAGCGTCAATCGCGTTCTGGGTGTTGCTTTTTGCGCAGCAGAAAAAAGAAGAACAGTAGGAGGG
CTCCATGTCCCAGATAGATA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDFQYTEKMQTLITQVRDFINNEIRPAENVYYEQLAKSPWETPPIMDELKEKARAKGLWNLFLPTEYAEYSAGLSNLEYA
PLAEEMGRCRIASEAFNCAAPDTGNMEVLAKYGNDAQKEQWLLPLLEGRIRSAFAMTEPQVASSDATNIETRITEDGDDY
IINGRKFYISGAMRKTCEIMIVMGKSSPDNPNRHQQQSQILVPTNTPGVNIVRPMQVFGYNDAPEGHADVIFDNVRVPKA
NIILGEGRGFEIAQGRLGPGRIHHCMRMIGAAQEAFEMMCKRVNQREVFGAPMSKQGSVREDIAKSYCEIEQARLLTLKA
ADAMDRSGNKDAKDLIAMIKVVAPNMALNVIDRAIQIHGAVGLSQDTPLVHFFSYARTLRLADGPDQVHMMQLGRNMAKQ
FA

Sequences:

>Translated_402_residues
MDFQYTEKMQTLITQVRDFINNEIRPAENVYYEQLAKSPWETPPIMDELKEKARAKGLWNLFLPTEYAEYSAGLSNLEYA
PLAEEMGRCRIASEAFNCAAPDTGNMEVLAKYGNDAQKEQWLLPLLEGRIRSAFAMTEPQVASSDATNIETRITEDGDDY
IINGRKFYISGAMRKTCEIMIVMGKSSPDNPNRHQQQSQILVPTNTPGVNIVRPMQVFGYNDAPEGHADVIFDNVRVPKA
NIILGEGRGFEIAQGRLGPGRIHHCMRMIGAAQEAFEMMCKRVNQREVFGAPMSKQGSVREDIAKSYCEIEQARLLTLKA
ADAMDRSGNKDAKDLIAMIKVVAPNMALNVIDRAIQIHGAVGLSQDTPLVHFFSYARTLRLADGPDQVHMMQLGRNMAKQ
FA
>Mature_402_residues
MDFQYTEKMQTLITQVRDFINNEIRPAENVYYEQLAKSPWETPPIMDELKEKARAKGLWNLFLPTEYAEYSAGLSNLEYA
PLAEEMGRCRIASEAFNCAAPDTGNMEVLAKYGNDAQKEQWLLPLLEGRIRSAFAMTEPQVASSDATNIETRITEDGDDY
IINGRKFYISGAMRKTCEIMIVMGKSSPDNPNRHQQQSQILVPTNTPGVNIVRPMQVFGYNDAPEGHADVIFDNVRVPKA
NIILGEGRGFEIAQGRLGPGRIHHCMRMIGAAQEAFEMMCKRVNQREVFGAPMSKQGSVREDIAKSYCEIEQARLLTLKA
ADAMDRSGNKDAKDLIAMIKVVAPNMALNVIDRAIQIHGAVGLSQDTPLVHFFSYARTLRLADGPDQVHMMQLGRNMAKQ
FA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI48976061, Length=385, Percent_Identity=56.6233766233766, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI211971008, Length=385, Percent_Identity=56.6233766233766, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI38505218, Length=410, Percent_Identity=51.219512195122, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI4557233, Length=396, Percent_Identity=28.5353535353535, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI7656849, Length=390, Percent_Identity=26.4102564102564, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4557231, Length=408, Percent_Identity=25.2450980392157, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI187960098, Length=408, Percent_Identity=25.2450980392157, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI4501859, Length=397, Percent_Identity=25.9445843828715, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI21361497, Length=379, Percent_Identity=26.3852242744063, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226958414, Length=388, Percent_Identity=25, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226958412, Length=347, Percent_Identity=25.6484149855908, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI76496475, Length=390, Percent_Identity=25.3846153846154, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4557235, Length=390, Percent_Identity=25.3846153846154, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=24.6719160104987, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=408, Percent_Identity=25.7352941176471, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786223, Length=408, Percent_Identity=23.5294117647059, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=394, Percent_Identity=52.5380710659898, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17534899, Length=407, Percent_Identity=26.044226044226, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17570075, Length=411, Percent_Identity=25.0608272506083, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17538396, Length=403, Percent_Identity=24.8138957816377, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=392, Percent_Identity=25.765306122449, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=26.9340974212034, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=24.802110817942, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=25, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=309, Percent_Identity=26.537216828479, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=319, Percent_Identity=26.0188087774295, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=386, Percent_Identity=24.8704663212435, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=29.2857142857143, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=25.4355400696864, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71982178, Length=292, Percent_Identity=26.3698630136986, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=396, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356377, Length=399, Percent_Identity=28.0701754385965, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24666513, Length=346, Percent_Identity=28.6127167630058, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24660351, Length=404, Percent_Identity=27.4752475247525, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=26.6839378238342, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=26.1096605744125, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21355753, Length=330, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920834, Length=334, Percent_Identity=26.0479041916168, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45000; Mature: 45000

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQYTEKMQTLITQVRDFINNEIRPAENVYYEQLAKSPWETPPIMDELKEKARAKGLWN
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEE
LFLPTEYAEYSAGLSNLEYAPLAEEMGRCRIASEAFNCAAPDTGNMEVLAKYGNDAQKEQ
ECCCCHHHHHHCCCCCCCCCCHHHHHCCEEEHHHHCCCCCCCCCCEEEEEECCCCHHHHH
WLLPLLEGRIRSAFAMTEPQVASSDATNIETRITEDGDDYIINGRKFYISGAMRKTCEIM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEECCEEEEEECHHHCCEEEE
IVMGKSSPDNPNRHQQQSQILVPTNTPGVNIVRPMQVFGYNDAPEGHADVIFDNVRVPKA
EEECCCCCCCCCCHHHHCEEEEECCCCCCCEECCHHHCCCCCCCCCCCCEEEECCCCCCC
NIILGEGRGFEIAQGRLGPGRIHHCMRMIGAAQEAFEMMCKRVNQREVFGAPMSKQGSVR
EEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHH
EDIAKSYCEIEQARLLTLKAADAMDRSGNKDAKDLIAMIKVVAPNMALNVIDRAIQIHGA
HHHHHHHHHHHHHHEEEEEHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
VGLSQDTPLVHFFSYARTLRLADGPDQVHMMQLGRNMAKQFA
CCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFQYTEKMQTLITQVRDFINNEIRPAENVYYEQLAKSPWETPPIMDELKEKARAKGLWN
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEE
LFLPTEYAEYSAGLSNLEYAPLAEEMGRCRIASEAFNCAAPDTGNMEVLAKYGNDAQKEQ
ECCCCHHHHHHCCCCCCCCCCHHHHHCCEEEHHHHCCCCCCCCCCEEEEEECCCCHHHHH
WLLPLLEGRIRSAFAMTEPQVASSDATNIETRITEDGDDYIINGRKFYISGAMRKTCEIM
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEECCEEEEEECHHHCCEEEE
IVMGKSSPDNPNRHQQQSQILVPTNTPGVNIVRPMQVFGYNDAPEGHADVIFDNVRVPKA
EEECCCCCCCCCCHHHHCEEEEECCCCCCCEECCHHHCCCCCCCCCCCCEEEECCCCCCC
NIILGEGRGFEIAQGRLGPGRIHHCMRMIGAAQEAFEMMCKRVNQREVFGAPMSKQGSVR
EEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHH
EDIAKSYCEIEQARLLTLKAADAMDRSGNKDAKDLIAMIKVVAPNMALNVIDRAIQIHGA
HHHHHHHHHHHHHHEEEEEHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
VGLSQDTPLVHFFSYARTLRLADGPDQVHMMQLGRNMAKQFA
CCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]