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The map label for this gene is wbpM [H]

Identifier: 110833789

GI number: 110833789

Start: 1037654

End: 1039543

Strand: Direct

Name: wbpM [H]

Synonym: ABO_0928

Alternate gene names: 110833789

Gene position: 1037654-1039543 (Clockwise)

Preceding gene: 110833788

Following gene: 110833790

Centisome position: 33.26

GC content: 56.88

Gene sequence:

>1890_bases
ATGGTAATGCTGGGTGCTGATGCAGTCGCCGCCCCCCTATTACTCTGGCTTGCCTATGGCTTGCGCCTCAATACCGCCGC
CCCGGAAGTGGCCGACCTATGGTTGCTGATGGCTACGCCGTTGGTGGTGCTGCCGGTGCTATATGCGTTCGGTTTTTACC
GTTCGGTTGTGCGTTACCTAGGGGCTGAAGTGGCGTGGTCTATCCTGTTTGGGGCGACTCTTTCGGTGGTGCTGCTGGCG
GCGACGACTTATATGGTATCGGGCTCTACCCCGCGTTCAGTGTTTATTATTTTCTGGGCGTTGCTAGTGCTATACCTAGG
GGGCAGCCGCTTTATGATGCGCCGTTTCCTTTATAACGTGCTAGGTAAGCATACTTTGCGTGAAGCGGTGGCGGTATTCG
GTGCTGGTGGAGCGGGGGCTCAGCTGGTGTCTGGGTTATTGTCTTCCACCGAGTTGCGCCCGCTGATGATAGTGGACGAT
GCGCCCGGTAAACAGGGGATGTTGCTTTGCGGTGTGCCGGTGGTGGGGCGGCGCGCTTTGGAAAAAGCGGTAGAACGGGG
GGCTATTCGTACGGTGTTACTGGCTCTGCCGTCTGAGAGCCGGGCGACACGGATGGCAGTGGTGCGCTGGCTGGAAACCC
TGAATGTGCATGTGCAGACGGTGCCTTCGTTTGCGGATATTGCTAGCGGCAAGGCGCGGCTTGAAGAAGTCAAAGACGTG
TCTATCGAAGACTTGCTGGGCCGTGACCCGGTGCCCCCCCGCGCGGATTTACTGTCGCGCTGTATTAGTGGTAAGCATGT
TCTGGTGACGGGCGCGGCGGGCTCCATTGGTAGCGAGCTTTGTCGCCAGATTCTTAAGTTGAACCCTTCCCGCTTGGTGT
TGCTCGATCAAAGTGAATTTGGCCTATATGCCATTGAGAAAGAATTGCGAGCAACGGCGGACAGCCTTGGTAAAAGCGTC
GAAATTGAGGCGGTGCTCGGTTCAGTGGTGAACCGGGGCTTGATGGAGCGGCTTTGCAGTGACCAACGGGTGGATACGGT
GTACCACGCCGCAGCGTACAAGCATGTGCCGATTGTGGAGGCTAACCCTACGGCTGGAGTGCGCAATAATATCTTGGGGA
CGCTGGAGGCCGCACTGGGAGCAGAAGCTGCTCATGTGAAGCACTTTATTCTTGTGTCCACGGATAAGGCTGTTCGCCCA
ACTAACGTGATGGGGGCCACTAAGCGTTTTGCAGAACTGGTGCTCCAGGCCATAGCCGCTAGGGGTTCGGACACCGTGTT
CTCGATGGTACGTTTTGGCAACGTGCTTGGCTCGTCTGGTTCGGTGGTGCCCTTGTTCCGTGACCAGATTCGTAAAGGCG
GCCCGGTAACGGTGACCCACCCGGATGTGATTCGCTATTTTATGACCATCCCTGAAGCGTCCCAGTTAGTGATTCAGGCG
GGTGCCATGGCCCAGGGCGGCGAAGTATTCGTGTTGGATATGGGTGAGCCGGTGCGAATTGTTGACTTGGCCCGCACCAT
GGTGCATTTGATGGGGATGACGGTGCGCGATGAGAAAATGCCGGAGGGTGACATTGAGATTGCCTTTTCCGGCCTGCGGC
CCGGTGAGAAGCTCTATGAAGAGTTATTGATTGGTGAGTGCAGCATCCGCACTGAGCATGAAATGATTATGCAGGCCCAT
GAGGAAAAGCTGAGCTGGGACGAGGTGCATTTTGCCCTGGAGGCGTTCCGTAAGGCGTTAAGCCGTGCCGACCAGGATGC
TCTGCGGGCTTTACTGCGTAGTTATGTCAATGGGTATCAGCCAGAGGGGGTGGGTGCTGAGTCACCCGAGAGCCTTGCGG
TACGTGAATTGCCGGCCTTTACCGGTAAAGCCGTTAGCGTTACGGAGTAG

Upstream 100 bases:

>100_bases
TGGCCGGCCCTTTGGTCGCATGGACTGACCTATTATGAAAAACAAGTACTTCTACTCCCCTGTGCACCGGATGGTGTCAC
TGCCTCGTACTGCCAAAAGA

Downstream 100 bases:

>100_bases
TCTTTTTTTGGGGGGGTATGTCGGGCGAATCCGGCTTACCTTGTCTTCCTTGCTTCTATGCGCTTATCGTTTAGGCCTGT
TGTCTAGGCCAGATTAGACG

Product: polysaccharide biosynthesis protein

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MVMLGADAVAAPLLLWLAYGLRLNTAAPEVADLWLLMATPLVVLPVLYAFGFYRSVVRYLGAEVAWSILFGATLSVVLLA
ATTYMVSGSTPRSVFIIFWALLVLYLGGSRFMMRRFLYNVLGKHTLREAVAVFGAGGAGAQLVSGLLSSTELRPLMIVDD
APGKQGMLLCGVPVVGRRALEKAVERGAIRTVLLALPSESRATRMAVVRWLETLNVHVQTVPSFADIASGKARLEEVKDV
SIEDLLGRDPVPPRADLLSRCISGKHVLVTGAAGSIGSELCRQILKLNPSRLVLLDQSEFGLYAIEKELRATADSLGKSV
EIEAVLGSVVNRGLMERLCSDQRVDTVYHAAAYKHVPIVEANPTAGVRNNILGTLEAALGAEAAHVKHFILVSTDKAVRP
TNVMGATKRFAELVLQAIAARGSDTVFSMVRFGNVLGSSGSVVPLFRDQIRKGGPVTVTHPDVIRYFMTIPEASQLVIQA
GAMAQGGEVFVLDMGEPVRIVDLARTMVHLMGMTVRDEKMPEGDIEIAFSGLRPGEKLYEELLIGECSIRTEHEMIMQAH
EEKLSWDEVHFALEAFRKALSRADQDALRALLRSYVNGYQPEGVGAESPESLAVRELPAFTGKAVSVTE

Sequences:

>Translated_629_residues
MVMLGADAVAAPLLLWLAYGLRLNTAAPEVADLWLLMATPLVVLPVLYAFGFYRSVVRYLGAEVAWSILFGATLSVVLLA
ATTYMVSGSTPRSVFIIFWALLVLYLGGSRFMMRRFLYNVLGKHTLREAVAVFGAGGAGAQLVSGLLSSTELRPLMIVDD
APGKQGMLLCGVPVVGRRALEKAVERGAIRTVLLALPSESRATRMAVVRWLETLNVHVQTVPSFADIASGKARLEEVKDV
SIEDLLGRDPVPPRADLLSRCISGKHVLVTGAAGSIGSELCRQILKLNPSRLVLLDQSEFGLYAIEKELRATADSLGKSV
EIEAVLGSVVNRGLMERLCSDQRVDTVYHAAAYKHVPIVEANPTAGVRNNILGTLEAALGAEAAHVKHFILVSTDKAVRP
TNVMGATKRFAELVLQAIAARGSDTVFSMVRFGNVLGSSGSVVPLFRDQIRKGGPVTVTHPDVIRYFMTIPEASQLVIQA
GAMAQGGEVFVLDMGEPVRIVDLARTMVHLMGMTVRDEKMPEGDIEIAFSGLRPGEKLYEELLIGECSIRTEHEMIMQAH
EEKLSWDEVHFALEAFRKALSRADQDALRALLRSYVNGYQPEGVGAESPESLAVRELPAFTGKAVSVTE
>Mature_629_residues
MVMLGADAVAAPLLLWLAYGLRLNTAAPEVADLWLLMATPLVVLPVLYAFGFYRSVVRYLGAEVAWSILFGATLSVVLLA
ATTYMVSGSTPRSVFIIFWALLVLYLGGSRFMMRRFLYNVLGKHTLREAVAVFGAGGAGAQLVSGLLSSTELRPLMIVDD
APGKQGMLLCGVPVVGRRALEKAVERGAIRTVLLALPSESRATRMAVVRWLETLNVHVQTVPSFADIASGKARLEEVKDV
SIEDLLGRDPVPPRADLLSRCISGKHVLVTGAAGSIGSELCRQILKLNPSRLVLLDQSEFGLYAIEKELRATADSLGKSV
EIEAVLGSVVNRGLMERLCSDQRVDTVYHAAAYKHVPIVEANPTAGVRNNILGTLEAALGAEAAHVKHFILVSTDKAVRP
TNVMGATKRFAELVLQAIAARGSDTVFSMVRFGNVLGSSGSVVPLFRDQIRKGGPVTVTHPDVIRYFMTIPEASQLVIQA
GAMAQGGEVFVLDMGEPVRIVDLARTMVHLMGMTVRDEKMPEGDIEIAFSGLRPGEKLYEELLIGECSIRTEHEMIMQAH
EEKLSWDEVHFALEAFRKALSRADQDALRALLRSYVNGYQPEGVGAESPESLAVRELPAFTGKAVSVTE

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 68083; Mature: 68083

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMLGADAVAAPLLLWLAYGLRLNTAAPEVADLWLLMATPLVVLPVLYAFGFYRSVVRYL
CEEECCHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEVAWSILFGATLSVVLLAATTYMVSGSTPRSVFIIFWALLVLYLGGSRFMMRRFLYNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGKHTLREAVAVFGAGGAGAQLVSGLLSSTELRPLMIVDDAPGKQGMLLCGVPVVGRRAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHH
EKAVERGAIRTVLLALPSESRATRMAVVRWLETLNVHVQTVPSFADIASGKARLEEVKDV
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCHHHHHHHHCC
SIEDLLGRDPVPPRADLLSRCISGKHVLVTGAAGSIGSELCRQILKLNPSRLVLLDQSEF
CHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCC
GLYAIEKELRATADSLGKSVEIEAVLGSVVNRGLMERLCSDQRVDTVYHAAAYKHVPIVE
CHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
ANPTAGVRNNILGTLEAALGAEAAHVKHFILVSTDKAVRPTNVMGATKRFAELVLQAIAA
CCCCCCHHHHHHHHHHHHHCCCHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
RGSDTVFSMVRFGNVLGSSGSVVPLFRDQIRKGGPVTVTHPDVIRYFMTIPEASQLVIQA
CCCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
GAMAQGGEVFVLDMGEPVRIVDLARTMVHLMGMTVRDEKMPEGDIEIAFSGLRPGEKLYE
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
ELLIGECSIRTEHEMIMQAHEEKLSWDEVHFALEAFRKALSRADQDALRALLRSYVNGYQ
HHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PEGVGAESPESLAVRELPAFTGKAVSVTE
CCCCCCCCCHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure
MVMLGADAVAAPLLLWLAYGLRLNTAAPEVADLWLLMATPLVVLPVLYAFGFYRSVVRYL
CEEECCHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEVAWSILFGATLSVVLLAATTYMVSGSTPRSVFIIFWALLVLYLGGSRFMMRRFLYNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGKHTLREAVAVFGAGGAGAQLVSGLLSSTELRPLMIVDDAPGKQGMLLCGVPVVGRRAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCHHHHHHH
EKAVERGAIRTVLLALPSESRATRMAVVRWLETLNVHVQTVPSFADIASGKARLEEVKDV
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCHHHHHHHHCC
SIEDLLGRDPVPPRADLLSRCISGKHVLVTGAAGSIGSELCRQILKLNPSRLVLLDQSEF
CHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCC
GLYAIEKELRATADSLGKSVEIEAVLGSVVNRGLMERLCSDQRVDTVYHAAAYKHVPIVE
CHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEE
ANPTAGVRNNILGTLEAALGAEAAHVKHFILVSTDKAVRPTNVMGATKRFAELVLQAIAA
CCCCCCHHHHHHHHHHHHHCCCHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHC
RGSDTVFSMVRFGNVLGSSGSVVPLFRDQIRKGGPVTVTHPDVIRYFMTIPEASQLVIQA
CCCHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHH
GAMAQGGEVFVLDMGEPVRIVDLARTMVHLMGMTVRDEKMPEGDIEIAFSGLRPGEKLYE
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
ELLIGECSIRTEHEMIMQAHEEKLSWDEVHFALEAFRKALSRADQDALRALLRSYVNGYQ
HHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PEGVGAESPESLAVRELPAFTGKAVSVTE
CCCCCCCCCHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]