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The map label for this gene is nadA [H]

Identifier: 110833631

GI number: 110833631

Start: 864441

End: 865490

Strand: Direct

Name: nadA [H]

Synonym: ABO_0770

Alternate gene names: 110833631

Gene position: 864441-865490 (Clockwise)

Preceding gene: 110833630

Following gene: 110833633

Centisome position: 27.71

GC content: 55.81

Gene sequence:

>1050_bases
ATGACGGCAGAGGCACAAGCACGGGTCCAGGCGCATTTAGCTGAGGTGGAGCCCGAGGACACGCTCAGCGAAGAGCAACG
CGCATCCTATCGTGATCGGATCAAGGCGTTGTTGCGTCAACGCGATGCGGTGTTGGTAGCGCATTACTACACAGACCCGG
AAATTCAGTCGTTGGCGGAAGAAACCGGTGGCTGTGTGTCTGATTCTTTGGAAATGGCCCGCTTTGGCAAAGACCATCCT
GCGTCCACGTTGATTGTGGCCGGGGTGAAGTTTATGGGTGAGACCGCCAAAATTCTTAGCCCGGAAAAACGCGTCTTCAT
GCCGACACTCGAAGCGACCTGTTCATTGGATATCGGTTGTCCGGAAGAAGAGTTTTCCGCATTTTGCGACCAGCACCCGG
ACCGCACTGTGGTGGTTTATGCCAATACTTCCGCTGCGGTGAAAGCCCGTGCCGATTGGGTGGTCACCTCGTCCATCGCC
GTGGAGTTGATTGAGCATCTAGATAGCAACGGTGAAAAAATTCTGTGGGCGCCGGACAAGCACCTTGGCGGCTATGTTCG
TGATAAAGCTGGCGCCGATGTATTGTGTTGGGACGGTGCCTGCATTGTTCACGAAGAGTTTAAAGCTAAAGGGTTGCATG
ATTTGCAAGCCGCCTACCCGGATGCCGCTATTCTGGTGCACCCGGAATCCCCGGCCTCGGTGGTGGAAATGGCGGATGTG
GTCGGCTCAACCTCACAGCTGATCAAGGCCGCTTGCGAGATGGACAATGAGGTGTTCATCGTTGCCACCGACAAGGGCAT
TTTCTACAAGATGCAGCAGTTAGCGCCGGGCAAAACCTTCTTGGAAGCGCCGACGGCGGGCTCCGGTGCGACCTGTCGCA
GTTGTGCTCACTGTCCGTGGATGGCAATGAATGGCCTGCAGAACATGCTCGCGGTGCTGGAAGATGCCAACGGCATGGGG
CAGGAAATTTTCGTGGACTCGTCGCTGGCAGAAAAAGCCATGGTGCCGTTGAACCGCATGTTGGATTTCGGCCGCAAGTT
GAAAGCGTGA

Upstream 100 bases:

>100_bases
TATTCAGCGGTTTTTGGCTGTTGTGGTATTATGCCCGCCTTATTCTTTTATCAATTTTCCAAGTTGTTGATTTCAGGGGG
AAACCCCGGGCGGTAAGGCA

Downstream 100 bases:

>100_bases
CCGGCCGCTATTATTTTGTGTGACGCCTGATACAACCTGTGCAAACAACGCAGGTTGTATTCTTGCGATTTAGACAGTAC
CCCGCCACCGCGCTCAGAAC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTAEAQARVQAHLAEVEPEDTLSEEQRASYRDRIKALLRQRDAVLVAHYYTDPEIQSLAEETGGCVSDSLEMARFGKDHP
ASTLIVAGVKFMGETAKILSPEKRVFMPTLEATCSLDIGCPEEEFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSIA
VELIEHLDSNGEKILWAPDKHLGGYVRDKAGADVLCWDGACIVHEEFKAKGLHDLQAAYPDAAILVHPESPASVVEMADV
VGSTSQLIKAACEMDNEVFIVATDKGIFYKMQQLAPGKTFLEAPTAGSGATCRSCAHCPWMAMNGLQNMLAVLEDANGMG
QEIFVDSSLAEKAMVPLNRMLDFGRKLKA

Sequences:

>Translated_349_residues
MTAEAQARVQAHLAEVEPEDTLSEEQRASYRDRIKALLRQRDAVLVAHYYTDPEIQSLAEETGGCVSDSLEMARFGKDHP
ASTLIVAGVKFMGETAKILSPEKRVFMPTLEATCSLDIGCPEEEFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSIA
VELIEHLDSNGEKILWAPDKHLGGYVRDKAGADVLCWDGACIVHEEFKAKGLHDLQAAYPDAAILVHPESPASVVEMADV
VGSTSQLIKAACEMDNEVFIVATDKGIFYKMQQLAPGKTFLEAPTAGSGATCRSCAHCPWMAMNGLQNMLAVLEDANGMG
QEIFVDSSLAEKAMVPLNRMLDFGRKLKA
>Mature_348_residues
TAEAQARVQAHLAEVEPEDTLSEEQRASYRDRIKALLRQRDAVLVAHYYTDPEIQSLAEETGGCVSDSLEMARFGKDHPA
STLIVAGVKFMGETAKILSPEKRVFMPTLEATCSLDIGCPEEEFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIEHLDSNGEKILWAPDKHLGGYVRDKAGADVLCWDGACIVHEEFKAKGLHDLQAAYPDAAILVHPESPASVVEMADVV
GSTSQLIKAACEMDNEVFIVATDKGIFYKMQQLAPGKTFLEAPTAGSGATCRSCAHCPWMAMNGLQNMLAVLEDANGMGQ
EIFVDSSLAEKAMVPLNRMLDFGRKLKA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=327, Percent_Identity=72.782874617737, Blast_Score=505, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37938; Mature: 37806

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEAQARVQAHLAEVEPEDTLSEEQRASYRDRIKALLRQRDAVLVAHYYTDPEIQSLAE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ETGGCVSDSLEMARFGKDHPASTLIVAGVKFMGETAKILSPEKRVFMPTLEATCSLDIGC
HHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHCCHHHHCCCCCCEEEEECCCEEEECCCC
PEEEFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSNGEKILWAPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGGYVRDKAGADVLCWDGACIVHEEFKAKGLHDLQAAYPDAAILVHPESPASVVEMADV
HCCCCHHHCCCCEEEEECCEEEEEHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAACEMDNEVFIVATDKGIFYKMQQLAPGKTFLEAPTAGSGATCRSCAHCPW
HCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCH
MAMNGLQNMLAVLEDANGMGQEIFVDSSLAEKAMVPLNRMLDFGRKLKA
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAEAQARVQAHLAEVEPEDTLSEEQRASYRDRIKALLRQRDAVLVAHYYTDPEIQSLAE
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ETGGCVSDSLEMARFGKDHPASTLIVAGVKFMGETAKILSPEKRVFMPTLEATCSLDIGC
HHCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHCCHHHHCCCCCCEEEEECCCEEEECCCC
PEEEFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSNGEKILWAPDK
CHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHCCCCCEEEECCCH
HLGGYVRDKAGADVLCWDGACIVHEEFKAKGLHDLQAAYPDAAILVHPESPASVVEMADV
HCCCCHHHCCCCEEEEECCEEEEEHHHHHCCCHHHHHCCCCCEEEEECCCCHHHHHHHHH
VGSTSQLIKAACEMDNEVFIVATDKGIFYKMQQLAPGKTFLEAPTAGSGATCRSCAHCPW
HCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCH
MAMNGLQNMLAVLEDANGMGQEIFVDSSLAEKAMVPLNRMLDFGRKLKA
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA