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The map label for this gene is cfa [H]

Identifier: 110833630

GI number: 110833630

Start: 863007

End: 864275

Strand: Direct

Name: cfa [H]

Synonym: ABO_0769

Alternate gene names: 110833630

Gene position: 863007-864275 (Clockwise)

Preceding gene: 110833629

Following gene: 110833631

Centisome position: 27.66

GC content: 55.71

Gene sequence:

>1269_bases
ATGCTGTCTGGCGATAGAGCCTCTAACAATAAAAGTATCCAGGCCGGCACATTGAGTTGGTCGCAATCAGTGGCTCGTAC
TCTGGTGTTGAATAAGCTGGCGAAAGTGCCACACGGCGGCCTGCGTATTGATGAGCCGGATGGAAACACCGTGTTACTCG
GCGATTCACACAATAGCCAGGCAATCGGCCATATCGTACTCACCGATTGGTGCACCTACAGCATGATGATGAGCGGTGGG
GCGATGGGGGCGGCAGAGGCGTTTATGGAACAAAGCTGGTCGAGCCCGGACCTGGTTAAGGTAATACGGTATTTCGCCGC
AAATGTGGACGCCATGCAAGCGCTGGAAGGCGGCTTTGCCGCGCTGTCCAAACCCGCGTTGAGAATGCTGCACCGCTATA
ATCGCAATTCGCTGCAAGGATCGCGCAGAAATATTTCCGCGCATTACGATCTGGGCAATGATTTTTTCAGCCTGTTTCTT
GATCGCACCATGATGTATTCCAGTGCGGTTTTTTCGCGCCCGGAGGCGTCCCTGGAGGAGGCCTCGGTGCACAAGCTGGA
TTTGATTTGCCAACGGCTGCAATTACAGCCCGGCATGACGGTGCTTGAAATTGGCACGGGCTGGGGCGGTTTAGCGCTGC
ATGCAGCGCAGCATTACGGGGTCACCGTTACCACCACAACGATATCCCGCGAGCAGGCCCGTTATGCCCGTGATCTGGTT
GCCGATGCCGGGCTAAGTGATCGCATCACCATTCTGGAAAAGGATTATCGCGAACTCACCGGACAGTATGACAGGGTGGT
GTCCGTGGAAATGATCGAAGCGGTGGGGGCGGAATTTTTGCCTGGCTATTTTGATGTGTTGGGCAAGCGTTTGAAGCCGG
AAGGGTTGCTGCTGATTCAGGCAATCACGGTGCCGGACCAGCGTTACCACTATGCATTGAAGCAGGTGGACTTCATTAAG
CGTTATATCTTTCCCGGCGGTTTCCTGCCCAGTGTGTCGGTGATGTGCGACAACCTCACGCGCCATACCCGCTTGGTGAC
CACGGAACTGCACGACATCGGTCATGATTACGCGCTGACCTTAAATCACTGGCGCCAGCGTTTTCATGATGCGCTGCCCC
GCATTCGCGAGCTGGGTTTTGATGAGCGGTTCGTGCGTATGTGGGAATATTACCTGTGCTATTGCGAGGGCGCGTTCCTG
GAGCGGGCCATCAGCACGGTGCATCTGGTTGCCGCCGGACCCGCTTACCGGCCTTCCTTCCAAGCTTGA

Upstream 100 bases:

>100_bases
CTGTGGCGTAAAGGCGCGGTCTTTCACGGTCACCCCGCTGGCGAGAACGCTCAACGTGATGATGGTGATTCAGGCGATGA
TGGAAACAGGGAGTAAGGTA

Downstream 100 bases:

>100_bases
AGGGAAGCTTGAAAACCGCCCTCGTCGGACGCATTTAATCCTTTGCAGGGCTAACAACAGGCCGCTATTCAGCGGTTTTT
GGCTGTTGTGGTATTATGCC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MLSGDRASNNKSIQAGTLSWSQSVARTLVLNKLAKVPHGGLRIDEPDGNTVLLGDSHNSQAIGHIVLTDWCTYSMMMSGG
AMGAAEAFMEQSWSSPDLVKVIRYFAANVDAMQALEGGFAALSKPALRMLHRYNRNSLQGSRRNISAHYDLGNDFFSLFL
DRTMMYSSAVFSRPEASLEEASVHKLDLICQRLQLQPGMTVLEIGTGWGGLALHAAQHYGVTVTTTTISREQARYARDLV
ADAGLSDRITILEKDYRELTGQYDRVVSVEMIEAVGAEFLPGYFDVLGKRLKPEGLLLIQAITVPDQRYHYALKQVDFIK
RYIFPGGFLPSVSVMCDNLTRHTRLVTTELHDIGHDYALTLNHWRQRFHDALPRIRELGFDERFVRMWEYYLCYCEGAFL
ERAISTVHLVAAGPAYRPSFQA

Sequences:

>Translated_422_residues
MLSGDRASNNKSIQAGTLSWSQSVARTLVLNKLAKVPHGGLRIDEPDGNTVLLGDSHNSQAIGHIVLTDWCTYSMMMSGG
AMGAAEAFMEQSWSSPDLVKVIRYFAANVDAMQALEGGFAALSKPALRMLHRYNRNSLQGSRRNISAHYDLGNDFFSLFL
DRTMMYSSAVFSRPEASLEEASVHKLDLICQRLQLQPGMTVLEIGTGWGGLALHAAQHYGVTVTTTTISREQARYARDLV
ADAGLSDRITILEKDYRELTGQYDRVVSVEMIEAVGAEFLPGYFDVLGKRLKPEGLLLIQAITVPDQRYHYALKQVDFIK
RYIFPGGFLPSVSVMCDNLTRHTRLVTTELHDIGHDYALTLNHWRQRFHDALPRIRELGFDERFVRMWEYYLCYCEGAFL
ERAISTVHLVAAGPAYRPSFQA
>Mature_422_residues
MLSGDRASNNKSIQAGTLSWSQSVARTLVLNKLAKVPHGGLRIDEPDGNTVLLGDSHNSQAIGHIVLTDWCTYSMMMSGG
AMGAAEAFMEQSWSSPDLVKVIRYFAANVDAMQALEGGFAALSKPALRMLHRYNRNSLQGSRRNISAHYDLGNDFFSLFL
DRTMMYSSAVFSRPEASLEEASVHKLDLICQRLQLQPGMTVLEIGTGWGGLALHAAQHYGVTVTTTTISREQARYARDLV
ADAGLSDRITILEKDYRELTGQYDRVVSVEMIEAVGAEFLPGYFDVLGKRLKPEGLLLIQAITVPDQRYHYALKQVDFIK
RYIFPGGFLPSVSVMCDNLTRHTRLVTTELHDIGHDYALTLNHWRQRFHDALPRIRELGFDERFVRMWEYYLCYCEGAFL
ERAISTVHLVAAGPAYRPSFQA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=360, Percent_Identity=38.0555555555556, Blast_Score=204, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI133904226, Length=366, Percent_Identity=36.6120218579235, Blast_Score=231, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47310; Mature: 47310

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGDRASNNKSIQAGTLSWSQSVARTLVLNKLAKVPHGGLRIDEPDGNTVLLGDSHNSQ
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCC
AIGHIVLTDWCTYSMMMSGGAMGAAEAFMEQSWSSPDLVKVIRYFAANVDAMQALEGGFA
CEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCHH
ALSKPALRMLHRYNRNSLQGSRRNISAHYDLGNDFFSLFLDRTMMYSSAVFSRPEASLEE
HHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ASVHKLDLICQRLQLQPGMTVLEIGTGWGGLALHAAQHYGVTVTTTTISREQARYARDLV
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHH
ADAGLSDRITILEKDYRELTGQYDRVVSVEMIEAVGAEFLPGYFDVLGKRLKPEGLLLIQ
HCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCHHHHHCCCCCCCCEEEEE
AITVPDQRYHYALKQVDFIKRYIFPGGFLPSVSVMCDNLTRHTRLVTTELHDIGHDYALT
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNHWRQRFHDALPRIRELGFDERFVRMWEYYLCYCEGAFLERAISTVHLVAAGPAYRPSF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCCCCC
QA
CC
>Mature Secondary Structure
MLSGDRASNNKSIQAGTLSWSQSVARTLVLNKLAKVPHGGLRIDEPDGNTVLLGDSHNSQ
CCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCCCCC
AIGHIVLTDWCTYSMMMSGGAMGAAEAFMEQSWSSPDLVKVIRYFAANVDAMQALEGGFA
CEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCHH
ALSKPALRMLHRYNRNSLQGSRRNISAHYDLGNDFFSLFLDRTMMYSSAVFSRPEASLEE
HHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ASVHKLDLICQRLQLQPGMTVLEIGTGWGGLALHAAQHYGVTVTTTTISREQARYARDLV
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHH
ADAGLSDRITILEKDYRELTGQYDRVVSVEMIEAVGAEFLPGYFDVLGKRLKPEGLLLIQ
HCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCHHHHHCCCCCCCCEEEEE
AITVPDQRYHYALKQVDFIKRYIFPGGFLPSVSVMCDNLTRHTRLVTTELHDIGHDYALT
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LNHWRQRFHDALPRIRELGFDERFVRMWEYYLCYCEGAFLERAISTVHLVAAGPAYRPSF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCCCCC
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]