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The map label for this gene is pilE [H]

Identifier: 110833476

GI number: 110833476

Start: 676258

End: 676704

Strand: Direct

Name: pilE [H]

Synonym: ABO_0615

Alternate gene names: 110833476

Gene position: 676258-676704 (Clockwise)

Preceding gene: 110833470

Following gene: 110833477

Centisome position: 21.67

GC content: 46.53

Gene sequence:

>447_bases
ATGAAGAAGCAAATGCAACAGGGTTTCACCCTTATTGAGCTGATGATTGTAGTTGCTATCATCGGTATCTTGGCTGCCGT
GGCTTTGCCTGCTTACCAGGATTATACAACTCGTGCAAAAATGTCAGAAGTTATTGGTTTTGCTGCATCCGCTAAAACTG
CGGTGACTGAATGTATCCAGAATGATAATGCGACGGCAGGTTGCAACTCTAATAGCGCAGTTGGAATGGATGAGGCCGAA
AACATTACCAGTACGTATGTAGAGTCTGTCACTGTTGGTGCTGATGGACAGGTGGTGGTTGCAATCCAAGGAACCAATGA
TGACACTCTTGATGCGGCATCTATTAGCTTGACTCCAAGCCTGAGTTCTGGTGGTGGTGTTAGCTGGAGCTGCGCACCTT
CTGCTACAAGTATTAACAAGTTCTTGCCAGCTAGCTGCCGCTCTTAA

Upstream 100 bases:

>100_bases
CGAGAATAAGTTTAAGTTGGCACGCTCCATGCTTTGACTTCATGTAGATGCTCGCCAAGGGGGAGCTCGAAAAAATTTGC
CAATGATTGGAGAAAACAAA

Downstream 100 bases:

>100_bases
TTTCGGATGGCTCGTTTGAATAAAGAGGGGGCGTTAGCCTCCTCTTTTTTATTTATCAGGTTTGAATGGCTTGTCCTGTT
AGGTTTGTCACTTTCCTTCT

Product: pilin family protein

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKKQMQQGFTLIELMIVVAIIGILAAVALPAYQDYTTRAKMSEVIGFAASAKTAVTECIQNDNATAGCNSNSAVGMDEAE
NITSTYVESVTVGADGQVVVAIQGTNDDTLDAASISLTPSLSSGGGVSWSCAPSATSINKFLPASCRS

Sequences:

>Translated_148_residues
MKKQMQQGFTLIELMIVVAIIGILAAVALPAYQDYTTRAKMSEVIGFAASAKTAVTECIQNDNATAGCNSNSAVGMDEAE
NITSTYVESVTVGADGQVVVAIQGTNDDTLDAASISLTPSLSSGGGVSWSCAPSATSINKFLPASCRS
>Mature_148_residues
MKKQMQQGFTLIELMIVVAIIGILAAVALPAYQDYTTRAKMSEVIGFAASAKTAVTECIQNDNATAGCNSNSAVGMDEAE
NITSTYVESVTVGADGQVVVAIQGTNDDTLDAASISLTPSLSSGGGVSWSCAPSATSINKFLPASCRS

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=126, Percent_Identity=34.9206349206349, Blast_Score=67, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15175; Mature: 15175

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQMQQGFTLIELMIVVAIIGILAAVALPAYQDYTTRAKMSEVIGFAASAKTAVTECIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NDNATAGCNSNSAVGMDEAENITSTYVESVTVGADGQVVVAIQGTNDDTLDAASISLTPS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCCEEEEECCC
LSSGGGVSWSCAPSATSINKFLPASCRS
CCCCCCCEEECCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKKQMQQGFTLIELMIVVAIIGILAAVALPAYQDYTTRAKMSEVIGFAASAKTAVTECIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NDNATAGCNSNSAVGMDEAENITSTYVESVTVGADGQVVVAIQGTNDDTLDAASISLTPS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCCEEEEECCC
LSSGGGVSWSCAPSATSINKFLPASCRS
CCCCCCCEEECCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3141743; 10710307; 8645220; 8993351; 9515697 [H]