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The map label for this gene is mutT [H]

Identifier: 110833470

GI number: 110833470

Start: 669953

End: 670891

Strand: Direct

Name: mutT [H]

Synonym: ABO_0609

Alternate gene names: 110833470

Gene position: 669953-670891 (Clockwise)

Preceding gene: 110833469

Following gene: 110833476

Centisome position: 21.47

GC content: 56.34

Gene sequence:

>939_bases
ATGCCAACAAGCCCAACCCCTTCAATCATTGTCGTTGCCGGTATTATTCGTGGTAGTGGCCATATTTGCCTGAGCAAGCG
TGCTGACCACCAGCATCAGGGTGGCTGCTGGGAATTCCCCGGTGGCAAGGTGGAGCCAGGTGAAACGCTGGGCGCAGCCT
TGGCTCGGGAGCTAGAGGAAGAGCTCGGCATGGTGGACGCAATCTCTACCCCCTTTATGACGATTGCCCATCAGTACGAT
GATTTACATGTGACCTTGCACTTTCGCGATGTGCATGCCTGGCAAGGCGAACCTGAAGGGAAGGAAGGGCAATCGGTGCA
GTGGTTTGTTCCGCAGGCATTGGCGGATTTGCGCTTTCCGGCGGCGAATCAACCGGTGGTGAATGCAATACGCTTGCCCG
AACAATTGGTGATTGCTCCGGAGGATATCTCACTTCATGAGTTATTGGCGGGTATTGATCGATTGGATGCAGGGCGACAG
GGGCTTTATCTGCGGCAGTGGAGCGACCATGCTGAAGTGTCGACCATCGTGGGGCTCTGTAATAAAAAAGGCCTAAAGGT
CTGGCTGCGAGCTTCAGGTCCACAGAGCGAGGTGATAGCGAAGGCGCTGGGTGTATTTGCCTTGCATTTTCCAGGGCGAG
TTCTGGCGCAATTGGATGAACGCCCCGCGTTTGATGGGATCACTAGTGCAGCGGTTCATGATCTGGCCTCACGGGACAAG
GCTGTGTCTCTTGGCCTGGATATGGCGCTGGTTTCGCCGGTCTTGCCCACGCCAACACACCCGGGTAAACCTGTATTAGG
CTGGCCGCAGGCTGAGGTGCTAATGAAAGGGACACCGCTTGCTTGTTATGCGTTGGGCGGAGTTATGCCGGGGGACCTGG
TCAGCGCTCGTGACTACGGTGCTGTTGGTGTTGCGGGGATCCGAGCTTTTTGGCGGTGA

Upstream 100 bases:

>100_bases
GTCGAATTAGCCTCAAAGGCGTAATCGCATAATGACAAACCGCTGAGCGCGTAAAGAGCTTGCTTGCACGCAGCTTCTCG
CAGAGATTTGGAAAACCCCC

Downstream 100 bases:

>100_bases
TGGGCTTCCACATACTCTACAGGCCCCCGCCTAGTCGACTGAGCGTGGTAGCGGCGCAACCTAGTATCTTCAATGTCTTA
TGGTAACTCATAGCCTGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPTSPTPSIIVVAGIIRGSGHICLSKRADHQHQGGCWEFPGGKVEPGETLGAALARELEEELGMVDAISTPFMTIAHQYD
DLHVTLHFRDVHAWQGEPEGKEGQSVQWFVPQALADLRFPAANQPVVNAIRLPEQLVIAPEDISLHELLAGIDRLDAGRQ
GLYLRQWSDHAEVSTIVGLCNKKGLKVWLRASGPQSEVIAKALGVFALHFPGRVLAQLDERPAFDGITSAAVHDLASRDK
AVSLGLDMALVSPVLPTPTHPGKPVLGWPQAEVLMKGTPLACYALGGVMPGDLVSARDYGAVGVAGIRAFWR

Sequences:

>Translated_312_residues
MPTSPTPSIIVVAGIIRGSGHICLSKRADHQHQGGCWEFPGGKVEPGETLGAALARELEEELGMVDAISTPFMTIAHQYD
DLHVTLHFRDVHAWQGEPEGKEGQSVQWFVPQALADLRFPAANQPVVNAIRLPEQLVIAPEDISLHELLAGIDRLDAGRQ
GLYLRQWSDHAEVSTIVGLCNKKGLKVWLRASGPQSEVIAKALGVFALHFPGRVLAQLDERPAFDGITSAAVHDLASRDK
AVSLGLDMALVSPVLPTPTHPGKPVLGWPQAEVLMKGTPLACYALGGVMPGDLVSARDYGAVGVAGIRAFWR
>Mature_311_residues
PTSPTPSIIVVAGIIRGSGHICLSKRADHQHQGGCWEFPGGKVEPGETLGAALARELEEELGMVDAISTPFMTIAHQYDD
LHVTLHFRDVHAWQGEPEGKEGQSVQWFVPQALADLRFPAANQPVVNAIRLPEQLVIAPEDISLHELLAGIDRLDAGRQG
LYLRQWSDHAEVSTIVGLCNKKGLKVWLRASGPQSEVIAKALGVFALHFPGRVLAQLDERPAFDGITSAAVHDLASRDKA
VSLGLDMALVSPVLPTPTHPGKPVLGWPQAEVLMKGTPLACYALGGVMPGDLVSARDYGAVGVAGIRAFWR

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus lea

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786288, Length=122, Percent_Identity=40.1639344262295, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788056, Length=122, Percent_Identity=34.4262295081967, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003561
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 33487; Mature: 33356

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSPTPSIIVVAGIIRGSGHICLSKRADHQHQGGCWEFPGGKVEPGETLGAALARELEE
CCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHH
ELGMVDAISTPFMTIAHQYDDLHVTLHFRDVHAWQGEPEGKEGQSVQWFVPQALADLRFP
HCCCHHHHCCCHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHCCCC
AANQPVVNAIRLPEQLVIAPEDISLHELLAGIDRLDAGRQGLYLRQWSDHAEVSTIVGLC
CCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
NKKGLKVWLRASGPQSEVIAKALGVFALHFPGRVLAQLDERPAFDGITSAAVHDLASRDK
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC
AVSLGLDMALVSPVLPTPTHPGKPVLGWPQAEVLMKGTPLACYALGGVMPGDLVSARDYG
EEECCCCHHHHCCCCCCCCCCCCCCCCCCCHHEEECCCCEEEEECCCCCCCCCCCCCCCC
AVGVAGIRAFWR
CHHHHHHHHHCC
>Mature Secondary Structure 
PTSPTPSIIVVAGIIRGSGHICLSKRADHQHQGGCWEFPGGKVEPGETLGAALARELEE
CCCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHH
ELGMVDAISTPFMTIAHQYDDLHVTLHFRDVHAWQGEPEGKEGQSVQWFVPQALADLRFP
HCCCHHHHCCCHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHCCCC
AANQPVVNAIRLPEQLVIAPEDISLHELLAGIDRLDAGRQGLYLRQWSDHAEVSTIVGLC
CCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHH
NKKGLKVWLRASGPQSEVIAKALGVFALHFPGRVLAQLDERPAFDGITSAAVHDLASRDK
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC
AVSLGLDMALVSPVLPTPTHPGKPVLGWPQAEVLMKGTPLACYALGGVMPGDLVSARDYG
EEECCCCHHHHCCCCCCCCCCCCCCCCCCCHHEEECCCCEEEEECCCCCCCCCCCCCCCC
AVGVAGIRAFWR
CHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3033442; 1630901; 9278503; 2841285; 8202364; 3288626; 1851162; 1309939; 7578113; 9063868 [H]