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The map label for this gene is hisC-1 [H]

Identifier: 110833424

GI number: 110833424

Start: 620582

End: 621709

Strand: Direct

Name: hisC-1 [H]

Synonym: ABO_0563

Alternate gene names: 110833424

Gene position: 620582-621709 (Clockwise)

Preceding gene: 110833423

Following gene: 110833425

Centisome position: 19.89

GC content: 53.81

Gene sequence:

>1128_bases
ATGAGTAAATATTGGAGCGACTTCGTTCACCATTTGGAGCCTTACGTTCCCGGCGAGCAGCCGAAGATGGACAAGTTAGT
GAAGTTAAATACCAACGAGCACCCGCTGGGTCCGTCGCCGAAGGTAATCGAGGCGATTCGGGGCGAAGTGGACGATCGGC
TGCGGCTGTATCCGGACCCGGATAGCAGCCAGCTGAAGCAGGCCATCGCCGACTATTATTCCGGCCTGGGCTATGGGATA
AAGCGTTCTCAGGTGTTCGTTGGCAATGGCTCCGACGAAGTGCTGGCGCATTTGTTCATGGGCTTTTTCAAACAGCATCA
GCCGCTACTTTTCCCAGATATCACCTATAGTTTCTACAAGGTCTATTGCGGCCTGTATCAAATCGACTATCAGCCTGTGC
CGCTCGATGATGCTCTGGGTATTGCGGTGGACGATTATCTAGAAGGCGACAAGCCACGCGCAAATGGTGGCATCATCTTC
CCTAACCCTAATGCGCCCACCGGTAAGCTGTTGCCGCTGAGTGAAATTGAGCGTTTGTTGCAGGCGAATACGCAAACCCT
GGTGGTTATCGATGAGGCCTATATCGACTTTGCCGGCCCCCAAGGGCAGGGCGGCGCTACGGCCATCGCTTTGGTAAACC
GCTACCCGAACCTGTTGGTGACTCAGACTTTGTCAAAATCCCGCTCTCTGGCGGGTTTGCGTATCGGCTTGGCGATTGGT
GATGGCGCGCTGATTGATGGGCTAAATCGGATTAAAGACAGCTTCAATTCCTATCCGTTGGATCGTCTGGCCATTGCCGC
TGGCGTGGCCGCGTTTAAAGATCAGGAGTGGTTCGAAAAAGGCTGTGAGCAAGTAATCATGCAGCGCGAGTGGCTCAACG
AGCAGCTCGGGCAGCGAGGTTTTGAGAGCTTGCCGTCGGCGGCCAACTTTCTTTTCACTCGCCACGAGCAGCATAGTGGG
CTCTCTCTGGCCCAGGGTTTGCGCGAGCAAGGCATTATTGTGCGTCATTTTGGCAAGCCTGAGCGTATCGCTGACTACCT
GAGAATCACTATTGGCACGCCTGAGCAAAATCAGGCGTTGATTGTGGCTTTAGATGGGTTGATTTCAAAGTGGAAAAACG
CCGGGTAA

Upstream 100 bases:

>100_bases
CCCGCAGTGCGGAATATAGAATCAAGAAACGCTAACACGCCTCACGCATCACGTTTCCACGGGTGATGCGTGTTGCCTGA
TGCATGCAGGCGGAATACGT

Downstream 100 bases:

>100_bases
TTTTTTGCTGAAATTACATAAAGAGGCCGTGCCCAAACTTTGGGCGCGGCCTCTTTATGTAAAGGAGTAACATTGCAGCT
TACTCGCTTTTGAGCTTTTA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSKYWSDFVHHLEPYVPGEQPKMDKLVKLNTNEHPLGPSPKVIEAIRGEVDDRLRLYPDPDSSQLKQAIADYYSGLGYGI
KRSQVFVGNGSDEVLAHLFMGFFKQHQPLLFPDITYSFYKVYCGLYQIDYQPVPLDDALGIAVDDYLEGDKPRANGGIIF
PNPNAPTGKLLPLSEIERLLQANTQTLVVIDEAYIDFAGPQGQGGATAIALVNRYPNLLVTQTLSKSRSLAGLRIGLAIG
DGALIDGLNRIKDSFNSYPLDRLAIAAGVAAFKDQEWFEKGCEQVIMQREWLNEQLGQRGFESLPSAANFLFTRHEQHSG
LSLAQGLREQGIIVRHFGKPERIADYLRITIGTPEQNQALIVALDGLISKWKNAG

Sequences:

>Translated_375_residues
MSKYWSDFVHHLEPYVPGEQPKMDKLVKLNTNEHPLGPSPKVIEAIRGEVDDRLRLYPDPDSSQLKQAIADYYSGLGYGI
KRSQVFVGNGSDEVLAHLFMGFFKQHQPLLFPDITYSFYKVYCGLYQIDYQPVPLDDALGIAVDDYLEGDKPRANGGIIF
PNPNAPTGKLLPLSEIERLLQANTQTLVVIDEAYIDFAGPQGQGGATAIALVNRYPNLLVTQTLSKSRSLAGLRIGLAIG
DGALIDGLNRIKDSFNSYPLDRLAIAAGVAAFKDQEWFEKGCEQVIMQREWLNEQLGQRGFESLPSAANFLFTRHEQHSG
LSLAQGLREQGIIVRHFGKPERIADYLRITIGTPEQNQALIVALDGLISKWKNAG
>Mature_374_residues
SKYWSDFVHHLEPYVPGEQPKMDKLVKLNTNEHPLGPSPKVIEAIRGEVDDRLRLYPDPDSSQLKQAIADYYSGLGYGIK
RSQVFVGNGSDEVLAHLFMGFFKQHQPLLFPDITYSFYKVYCGLYQIDYQPVPLDDALGIAVDDYLEGDKPRANGGIIFP
NPNAPTGKLLPLSEIERLLQANTQTLVVIDEAYIDFAGPQGQGGATAIALVNRYPNLLVTQTLSKSRSLAGLRIGLAIGD
GALIDGLNRIKDSFNSYPLDRLAIAAGVAAFKDQEWFEKGCEQVIMQREWLNEQLGQRGFESLPSAANFLFTRHEQHSGL
SLAQGLREQGIIVRHFGKPERIADYLRITIGTPEQNQALIVALDGLISKWKNAG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=368, Percent_Identity=28.5326086956522, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788722, Length=259, Percent_Identity=25.4826254826255, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=390, Percent_Identity=28.974358974359, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 41629; Mature: 41498

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYWSDFVHHLEPYVPGEQPKMDKLVKLNTNEHPLGPSPKVIEAIRGEVDDRLRLYPDP
CCHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEECCCC
DSSQLKQAIADYYSGLGYGIKRSQVFVGNGSDEVLAHLFMGFFKQHQPLLFPDITYSFYK
CHHHHHHHHHHHHHHCCCCCEECEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VYCGLYQIDYQPVPLDDALGIAVDDYLEGDKPRANGGIIFPNPNAPTGKLLPLSEIERLL
HHHHHHEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHH
QANTQTLVVIDEAYIDFAGPQGQGGATAIALVNRYPNLLVTQTLSKSRSLAGLRIGLAIG
HCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEHHHHHHCCCCCEEEEEEEEC
DGALIDGLNRIKDSFNSYPLDRLAIAAGVAAFKDQEWFEKGCEQVIMQREWLNEQLGQRG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FESLPSAANFLFTRHEQHSGLSLAQGLREQGIIVRHFGKPERIADYLRITIGTPEQNQAL
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHEEEEECCCCCCCEE
IVALDGLISKWKNAG
EEEEHHHHHHHCCCC
>Mature Secondary Structure 
SKYWSDFVHHLEPYVPGEQPKMDKLVKLNTNEHPLGPSPKVIEAIRGEVDDRLRLYPDP
CHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEECCCC
DSSQLKQAIADYYSGLGYGIKRSQVFVGNGSDEVLAHLFMGFFKQHQPLLFPDITYSFYK
CHHHHHHHHHHHHHHCCCCCEECEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VYCGLYQIDYQPVPLDDALGIAVDDYLEGDKPRANGGIIFPNPNAPTGKLLPLSEIERLL
HHHHHHEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHH
QANTQTLVVIDEAYIDFAGPQGQGGATAIALVNRYPNLLVTQTLSKSRSLAGLRIGLAIG
HCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCEEHHHHHHCCCCCEEEEEEEEC
DGALIDGLNRIKDSFNSYPLDRLAIAAGVAAFKDQEWFEKGCEQVIMQREWLNEQLGQRG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FESLPSAANFLFTRHEQHSGLSLAQGLREQGIIVRHFGKPERIADYLRITIGTPEQNQAL
HHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHEEEEECCCCCCCEE
IVALDGLISKWKNAG
EEEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA