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The map label for this gene is murA

Identifier: 110833421

GI number: 110833421

Start: 617117

End: 618379

Strand: Direct

Name: murA

Synonym: ABO_0560

Alternate gene names: 110833421

Gene position: 617117-618379 (Clockwise)

Preceding gene: 110833420

Following gene: 110833422

Centisome position: 19.78

GC content: 56.53

Gene sequence:

>1263_bases
ATGGATAAATTGATCATCACCGGTGGCCAGCGGTTGGACGGCGACATTCGCATTTCTGGGGCCAAGAATGCGGCGCTGCC
GATTCTGGCAGCCACTTTGTTGGCTGACGAGCCGGTAACGGTGGGCAACCTGCCGCATTTGCAGGACGTGACCACCCTGA
TCGAATTGTTGGGCCGGATGGGTGTCCATGTGGTGATCGATGACCGCATGAACGTGGAAGTGAACGCCACCACCATCAAG
GAATTGACGGCCCCCTATGAGCTGGTGAAAACCATGCGTGCCTCGATTCTGGTGCTGGGTCCCATGGTTGCGCATTTTGG
TAAAGCATCGGTATCGCTGCCCGGCGGTTGTGCTATTGGCTCGCGGCCGGTGGATATTCACCTGCGTGGCTTGGAGGCCA
TGGGCGCGGATATCGAGGTGACTAACGGTTATGTGAATGCTTCTGTGGATGGCCGGCTCAAAGGAGCACGCATCGTCATG
GATGTGGTCACCGTAACTGGTACCGAAAACTTGATGATGGCCGCGGCGCTGGCCGAAGGGACTACCTATCTTGAAAACGC
AGCCCGTGAGCCTGAAGTGGTGGATCTGGCCGATTTCATCAATGCCATGGGCGGCAAGATCAGCGGTGCCGGCACCGATA
CCATTACCATCGAAGGGGTGGAACGCCTGACCGGATGTCATCATCAGGTGATTGCCGATCGCATCGAAACCGGTACCTAC
CTGATTGCCGCGGCCATTACTGGTGGGCGCATTAAGACTAAAGACACGGTGCCGGGTACCCTTGATGCCGTACTGCAGAA
ACTGGAAGAAGCTGGTGCGAAGATTACTACCGGTGACGATTGGATTGAGCTGGATATGCAAGGCCGTCGCCCGAAGGCGG
TGTCGTTGCGCACAGCCCCATACCCGGCCATGCCCACTGACATGCAGGCCCAGTTCATGGCCCTGAATCTAGTGGCCGAA
GGCACCGGTACTATTGTTGAAACCATTTTTGAAAATCGTTTTATGCACGTGCAGGAAATGAACCGCATGGGCGCGGATAT
CGAGGTGCAAGGCAATACGGCTATTTGCCGTGGCGTGGAGCAACTCACTGGAGCACCGGTGATGGCCACGGATTTGCGCG
CCTCTGCTTCACTGGTTATTGCGGCATTGGCCGCGTCCGGTGAAACCACCGTGGACCGTATTTACCATATTGATCGCGGT
TATGAGTGTATCGAAGAGAAACTGCAATCGCTGGGCGCGATCATCCGTCGCGTACCACGCTGA

Upstream 100 bases:

>100_bases
TTTACTCCGGCGGAGTGGGAAAAAGCCCAGAATCAGGGCCTGTCCTGACCCCGGCCTTTGGCTGAACGGGTTGGAAGAAA
GAAACCATTAGAGACAGTTC

Downstream 100 bases:

>100_bases
CCGGATCGGGACCTGTGATGAGTAAGCCATTGACCATCGCCCTTTCTAAAGGGCGCATTCTCAAGGAAACCCTGCCGCTG
CTGAAAGCCGCAGGCATTGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKLIITGGQRLDGDIRISGAKNAALPILAATLLADEPVTVGNLPHLQDVTTLIELLGRMGVHVVIDDRMNVEVNATTIK
ELTAPYELVKTMRASILVLGPMVAHFGKASVSLPGGCAIGSRPVDIHLRGLEAMGADIEVTNGYVNASVDGRLKGARIVM
DVVTVTGTENLMMAAALAEGTTYLENAAREPEVVDLADFINAMGGKISGAGTDTITIEGVERLTGCHHQVIADRIETGTY
LIAAAITGGRIKTKDTVPGTLDAVLQKLEEAGAKITTGDDWIELDMQGRRPKAVSLRTAPYPAMPTDMQAQFMALNLVAE
GTGTIVETIFENRFMHVQEMNRMGADIEVQGNTAICRGVEQLTGAPVMATDLRASASLVIAALAASGETTVDRIYHIDRG
YECIEEKLQSLGAIIRRVPR

Sequences:

>Translated_420_residues
MDKLIITGGQRLDGDIRISGAKNAALPILAATLLADEPVTVGNLPHLQDVTTLIELLGRMGVHVVIDDRMNVEVNATTIK
ELTAPYELVKTMRASILVLGPMVAHFGKASVSLPGGCAIGSRPVDIHLRGLEAMGADIEVTNGYVNASVDGRLKGARIVM
DVVTVTGTENLMMAAALAEGTTYLENAAREPEVVDLADFINAMGGKISGAGTDTITIEGVERLTGCHHQVIADRIETGTY
LIAAAITGGRIKTKDTVPGTLDAVLQKLEEAGAKITTGDDWIELDMQGRRPKAVSLRTAPYPAMPTDMQAQFMALNLVAE
GTGTIVETIFENRFMHVQEMNRMGADIEVQGNTAICRGVEQLTGAPVMATDLRASASLVIAALAASGETTVDRIYHIDRG
YECIEEKLQSLGAIIRRVPR
>Mature_420_residues
MDKLIITGGQRLDGDIRISGAKNAALPILAATLLADEPVTVGNLPHLQDVTTLIELLGRMGVHVVIDDRMNVEVNATTIK
ELTAPYELVKTMRASILVLGPMVAHFGKASVSLPGGCAIGSRPVDIHLRGLEAMGADIEVTNGYVNASVDGRLKGARIVM
DVVTVTGTENLMMAAALAEGTTYLENAAREPEVVDLADFINAMGGKISGAGTDTITIEGVERLTGCHHQVIADRIETGTY
LIAAAITGGRIKTKDTVPGTLDAVLQKLEEAGAKITTGDDWIELDMQGRRPKAVSLRTAPYPAMPTDMQAQFMALNLVAE
GTGTIVETIFENRFMHVQEMNRMGADIEVQGNTAICRGVEQLTGAPVMATDLRASASLVIAALAASGETTVDRIYHIDRG
YECIEEKLQSLGAIIRRVPR

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=63.1578947368421, Blast_Score=528, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_ALCBS (Q0VS40)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692280.1
- ProteinModelPortal:   Q0VS40
- SMR:   Q0VS40
- STRING:   Q0VS40
- GeneID:   4211239
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0560
- NMPDR:   fig|393595.12.peg.558
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q0VS40
- BioCyc:   ABOR393595:ABO_0560-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44691; Mature: 44691

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLIITGGQRLDGDIRISGAKNAALPILAATLLADEPVTVGNLPHLQDVTTLIELLGRM
CCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHC
GVHVVIDDRMNVEVNATTIKELTAPYELVKTMRASILVLGPMVAHFGKASVSLPGGCAIG
CEEEEEECCCEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SRPVDIHLRGLEAMGADIEVTNGYVNASVDGRLKGARIVMDVVTVTGTENLMMAAALAEG
CCCEEEEEECHHHCCCCEEEECCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHCC
TTYLENAAREPEVVDLADFINAMGGKISGAGTDTITIEGVERLTGCHHQVIADRIETGTY
HHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEECCHHHHHCHHHHHHHHHHCCCCE
LIAAAITGGRIKTKDTVPGTLDAVLQKLEEAGAKITTGDDWIELDMQGRRPKAVSLRTAP
EEEEEEECCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPAMPTDMQAQFMALNLVAEGTGTIVETIFENRFMHVQEMNRMGADIEVQGNTAICRGVE
CCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCEEECCCHHHHHHHH
QLTGAPVMATDLRASASLVIAALAASGETTVDRIYHIDRGYECIEEKLQSLGAIIRRVPR
HHCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKLIITGGQRLDGDIRISGAKNAALPILAATLLADEPVTVGNLPHLQDVTTLIELLGRM
CCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHC
GVHVVIDDRMNVEVNATTIKELTAPYELVKTMRASILVLGPMVAHFGKASVSLPGGCAIG
CEEEEEECCCEEEEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SRPVDIHLRGLEAMGADIEVTNGYVNASVDGRLKGARIVMDVVTVTGTENLMMAAALAEG
CCCEEEEEECHHHCCCCEEEECCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHCC
TTYLENAAREPEVVDLADFINAMGGKISGAGTDTITIEGVERLTGCHHQVIADRIETGTY
HHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCEEEECCHHHHHCHHHHHHHHHHCCCCE
LIAAAITGGRIKTKDTVPGTLDAVLQKLEEAGAKITTGDDWIELDMQGRRPKAVSLRTAP
EEEEEEECCEEEECCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEECCC
YPAMPTDMQAQFMALNLVAEGTGTIVETIFENRFMHVQEMNRMGADIEVQGNTAICRGVE
CCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHCCCCEEECCCHHHHHHHH
QLTGAPVMATDLRASASLVIAALAASGETTVDRIYHIDRGYECIEEKLQSLGAIIRRVPR
HHCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA