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The map label for this gene is lspA [H]

Identifier: 110833321

GI number: 110833321

Start: 501683

End: 502195

Strand: Direct

Name: lspA [H]

Synonym: ABO_0460

Alternate gene names: 110833321

Gene position: 501683-502195 (Clockwise)

Preceding gene: 110833320

Following gene: 110833322

Centisome position: 16.08

GC content: 54.58

Gene sequence:

>513_bases
ATGCCAGGCAGTGCCAAGAAATGGCTACCCGGTCAGCTGTCCTGGTTGTGGCTGACGACGCTGATTATCGTGCTGGATCA
GTGGACCAAGCATGAAGTGGTGGCGGTGTTTACCCTGTATGAGCGGCTGGAAGTGTTTCCGCATTTTAATTTAACCCTGG
CCTATAACAGCGGCGCCGCATTCAGCTTTCTGGCCGATGCAGGCGGCTGGCAGCGCTGGTTCTTTACTGCCATAGCGGTG
GGCGCCTCGGTGATGATTTTGATCTGGCTGGCCCGGCTTACGGCTGCGGAAAAGCTGCAAGGGGTGGCGCTGTCGCTGAT
TCTGGCCGGTGCGTTGGGCAATTTTTACGATCGGTTGGTGTTGGGGCATGTGGTCGACTTTCTAGACTTCTACTGGGGCG
ATTATCATTTTCCCGCTTTCAATATTGCCGACACCGCCATTACCCTTGGGGCCGCATTGATCCTGCTGGAAATGCTGCTG
TCAGCGAAAAGAGAGCGTAAAAATAATGAGTGA

Upstream 100 bases:

>100_bases
GCTGAGCACCCTGAGTTGTGCGGGCGCTGCATTACCAATGTAGAGGGTGACGGCGAGGTTCGACACTATGCCTGATCACA
AGTCGGACGTCGGGCGCCAG

Downstream 100 bases:

>100_bases
GTTGCTTCGCGTAGGCCCGGAAACCCGGATTACGCTGCATTTTGCCGTGCGTCTGATGGATGGCACGGATCTGGATTCTA
CCTTTGATGGCGAGCCTGCT

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MPGSAKKWLPGQLSWLWLTTLIIVLDQWTKHEVVAVFTLYERLEVFPHFNLTLAYNSGAAFSFLADAGGWQRWFFTAIAV
GASVMILIWLARLTAAEKLQGVALSLILAGALGNFYDRLVLGHVVDFLDFYWGDYHFPAFNIADTAITLGAALILLEMLL
SAKRERKNNE

Sequences:

>Translated_170_residues
MPGSAKKWLPGQLSWLWLTTLIIVLDQWTKHEVVAVFTLYERLEVFPHFNLTLAYNSGAAFSFLADAGGWQRWFFTAIAV
GASVMILIWLARLTAAEKLQGVALSLILAGALGNFYDRLVLGHVVDFLDFYWGDYHFPAFNIADTAITLGAALILLEMLL
SAKRERKNNE
>Mature_169_residues
PGSAKKWLPGQLSWLWLTTLIIVLDQWTKHEVVAVFTLYERLEVFPHFNLTLAYNSGAAFSFLADAGGWQRWFFTAIAVG
ASVMILIWLARLTAAEKLQGVALSLILAGALGNFYDRLVLGHVVDFLDFYWGDYHFPAFNIADTAITLGAALILLEMLLS
AKRERKNNE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=155, Percent_Identity=50.3225806451613, Blast_Score=162, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19078; Mature: 18947

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGSAKKWLPGQLSWLWLTTLIIVLDQWTKHEVVAVFTLYERLEVFPHFNLTLAYNSGAA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
FSFLADAGGWQRWFFTAIAVGASVMILIWLARLTAAEKLQGVALSLILAGALGNFYDRLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHVVDFLDFYWGDYHFPAFNIADTAITLGAALILLEMLLSAKRERKNNE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PGSAKKWLPGQLSWLWLTTLIIVLDQWTKHEVVAVFTLYERLEVFPHFNLTLAYNSGAA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCH
FSFLADAGGWQRWFFTAIAVGASVMILIWLARLTAAEKLQGVALSLILAGALGNFYDRLV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGHVVDFLDFYWGDYHFPAFNIADTAITLGAALILLEMLLSAKRERKNNE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA