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The map label for this gene is zur [H]

Identifier: 110681132

GI number: 110681132

Start: 3861289

End: 3861804

Strand: Direct

Name: zur [H]

Synonym: RD1_4005

Alternate gene names: 110681132

Gene position: 3861289-3861804 (Clockwise)

Preceding gene: 110681130

Following gene: 110681133

Centisome position: 93.42

GC content: 63.76

Gene sequence:

>516_bases
ATGACAAGTGATTCGACGGAGAACGGCACGAACAGCGGCCCGCTCGGCTTTGCGCTGCATGATCATGACGCATGCGTCAG
TGACACGCTGGCCGCCGCCGAGGCACGCTGCGCGGCGGATGGTCTGCGTTTCACGCCTGTGCGCCGCAAGGTGCTTGAGA
TCCTGCTGCAGGAGCATCGCGCGCTCGGTGCCTATGCGATCCTTGACCGACTGCGCGAAGACGGGTTCGGATCACAGCCG
CCTGTCGCCTACCGCGCCCTGGATTTTCTGGTGATGAACGGTCTGGCGCATAAGATCGAGCAACTGAATGCCTTCATCGC
ATGCGTCCACCCCAGCGAAGCGCATACCCCTGCCTTCATGATCTGCCGTCTGTGTGACGCTGTGGCCGAAACGCAGTCCT
CGCCTGCGAAAGGGGCATTGGGGGACGCCGCGCGCGCCACCGGCTTTCGGATCGAACGCACCGTCGTCGAAGCGGAGGGC
ATCTGCCCGGCCTGCGCGGAAAAGGAAGACGCATGA

Upstream 100 bases:

>100_bases
GTCAGCGCGACTGTCAGGGAAAGGGCGAGACGCATTCTGGACATTCGAAATACCATGTGATTATATAACATTACGGCCGA
GATAAGCGAAATGTAATAAC

Downstream 100 bases:

>100_bases
GCCTTGTTGACGTTGACGGGCTCAGCCTCCGCTATGGGGCCAGAACAGTCCTGTCGCGCGTTTCCCTGAGCATCGCACCG
GGTGAAATCGTCACGATCGT

Product: zinc uptake regulation protein

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MTSDSTENGTNSGPLGFALHDHDACVSDTLAAAEARCAADGLRFTPVRRKVLEILLQEHRALGAYAILDRLREDGFGSQP
PVAYRALDFLVMNGLAHKIEQLNAFIACVHPSEAHTPAFMICRLCDAVAETQSSPAKGALGDAARATGFRIERTVVEAEG
ICPACAEKEDA

Sequences:

>Translated_171_residues
MTSDSTENGTNSGPLGFALHDHDACVSDTLAAAEARCAADGLRFTPVRRKVLEILLQEHRALGAYAILDRLREDGFGSQP
PVAYRALDFLVMNGLAHKIEQLNAFIACVHPSEAHTPAFMICRLCDAVAETQSSPAKGALGDAARATGFRIERTVVEAEG
ICPACAEKEDA
>Mature_170_residues
TSDSTENGTNSGPLGFALHDHDACVSDTLAAAEARCAADGLRFTPVRRKVLEILLQEHRALGAYAILDRLREDGFGSQPP
VAYRALDFLVMNGLAHKIEQLNAFIACVHPSEAHTPAFMICRLCDAVAETQSSPAKGALGDAARATGFRIERTVVEAEGI
CPACAEKEDA

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=144, Percent_Identity=38.8888888888889, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18238; Mature: 18107

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDSTENGTNSGPLGFALHDHDACVSDTLAAAEARCAADGLRFTPVRRKVLEILLQEHR
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ALGAYAILDRLREDGFGSQPPVAYRALDFLVMNGLAHKIEQLNAFIACVHPSEAHTPAFM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHH
ICRLCDAVAETQSSPAKGALGDAARATGFRIERTVVEAEGICPACAEKEDA
HHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TSDSTENGTNSGPLGFALHDHDACVSDTLAAAEARCAADGLRFTPVRRKVLEILLQEHR
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ALGAYAILDRLREDGFGSQPPVAYRALDFLVMNGLAHKIEQLNAFIACVHPSEAHTPAFM
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHH
ICRLCDAVAETQSSPAKGALGDAARATGFRIERTVVEAEGICPACAEKEDA
HHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]