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The map label for this gene is lldD [H]

Identifier: 110681035

GI number: 110681035

Start: 3764341

End: 3765510

Strand: Direct

Name: lldD [H]

Synonym: RD1_3896

Alternate gene names: 110681035

Gene position: 3764341-3765510 (Clockwise)

Preceding gene: 110681034

Following gene: 110681037

Centisome position: 91.08

GC content: 59.06

Gene sequence:

>1170_bases
ATGGCGGCTATTACCACAATCCAGGATCTGAAAGACCTGCACGAACGCCGTGTGCCCCGGATGTTTTACGACTACGCCGA
AAGCGGCAGCTGGACGGAACAGACGTTCCACGAAAACACCACCGATTTTGCGAAAATCCGCCTCAGGCAGCGGGTTGCCG
TGGATATGACCGGGCGCAGCACCGCGGGCCGGATGATTGGCGAGGATGTCGCCATGCCGGTGGCTCTGGCACCCGTCGGC
TCAACCGGCATGCAGCATGCGGATGGTGAAATCCTCGCAGCACAGGCCGCTGAGGCCTTTGGCGTGCCTTTTACGCTGTC
AACGATGTCGATCTGTTCCATTGAGGATGTCGCCGCCAATACCAGCAAGCCGTTCTGGTTCCAGCTTTATGCAATGAAGG
ACAAACGCTTTGTGGAGCGGGTCATCCAGCGCGCCAAGGACGCGAAATGCTCGGCGCTCGTGCTGACGCTTGATTTGCAA
ATACTCGGGCAACGTCACAAGGACATCAAGAACGGGCTGAGCATTCCGATCAAGCCGACGGTGCCCAACCTCATCGACCT
TGCCACCAAATGGCGCTGGATTGCAGCCATGGCGAAAACCAAACGCCGCCAGTTCGGCAATATCGTAGGCCATATTGAGG
GCATCAGTGACATGACATCCCTGTCGATCTGGGCTGCCGAAAGCTTTGATCCCAAACTGAACTGGGACGAGGTCAAGGAA
ATCAAGAAGATGTGGGGCGGACCACTCATCCTCAAGGGTATTCTGGATGCTGAGGATGCCAGGATGGCGCTGAATGTCGG
CGCGGATGCAATTGTCGTATCAAACCACGGCGGGCGGCAACTGGATGGGGCGCTGTCGTCGATCCGGGCGCTTCCGGCGA
TTCTGGACGCGGTTGGCGACAAGGTCGAGGTGCATATGGATGGCGGCATCCGCTCTGGTCAGGACGTGTTGAAAGCCTTG
GCGCTGGGGGCAAAGGGCACCTACATCGGCCGCGCCTTTGTGCACGGGCTGGGGGCGATGGGTGGTCCCGGCGTGACCAA
GGCGCTGGAGATCATCCACAAGGAACTGGACACCACCATGGCGCTCTGTGGGGAGACCGATGTCGCTGACCTTGGGCGGC
ATAACCTTTTGGTGCCAAAGGATTTCGAGGGGCAGTGGCAGTCGCCTTGA

Upstream 100 bases:

>100_bases
GCGCCGGTTCGCGGCAGAACCGGCAAAAACCCAAAGCGTTAAGCGATTGATCTTTGCGGGTCCGATTGGTAACGAAAAAT
GACCAATACGAGGGGACATC

Downstream 100 bases:

>100_bases
TGCGTCAATGACCTGCGGGGGTGTTCAGGCATCCCTGACCGGATGTGCGGCGGCGCTGCGCCCCAGGGCGGGCAAGAGAA
CGAGGGCCGTGACCACCATG

Product: putative L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAAITTIQDLKDLHERRVPRMFYDYAESGSWTEQTFHENTTDFAKIRLRQRVAVDMTGRSTAGRMIGEDVAMPVALAPVG
STGMQHADGEILAAQAAEAFGVPFTLSTMSICSIEDVAANTSKPFWFQLYAMKDKRFVERVIQRAKDAKCSALVLTLDLQ
ILGQRHKDIKNGLSIPIKPTVPNLIDLATKWRWIAAMAKTKRRQFGNIVGHIEGISDMTSLSIWAAESFDPKLNWDEVKE
IKKMWGGPLILKGILDAEDARMALNVGADAIVVSNHGGRQLDGALSSIRALPAILDAVGDKVEVHMDGGIRSGQDVLKAL
ALGAKGTYIGRAFVHGLGAMGGPGVTKALEIIHKELDTTMALCGETDVADLGRHNLLVPKDFEGQWQSP

Sequences:

>Translated_389_residues
MAAITTIQDLKDLHERRVPRMFYDYAESGSWTEQTFHENTTDFAKIRLRQRVAVDMTGRSTAGRMIGEDVAMPVALAPVG
STGMQHADGEILAAQAAEAFGVPFTLSTMSICSIEDVAANTSKPFWFQLYAMKDKRFVERVIQRAKDAKCSALVLTLDLQ
ILGQRHKDIKNGLSIPIKPTVPNLIDLATKWRWIAAMAKTKRRQFGNIVGHIEGISDMTSLSIWAAESFDPKLNWDEVKE
IKKMWGGPLILKGILDAEDARMALNVGADAIVVSNHGGRQLDGALSSIRALPAILDAVGDKVEVHMDGGIRSGQDVLKAL
ALGAKGTYIGRAFVHGLGAMGGPGVTKALEIIHKELDTTMALCGETDVADLGRHNLLVPKDFEGQWQSP
>Mature_388_residues
AAITTIQDLKDLHERRVPRMFYDYAESGSWTEQTFHENTTDFAKIRLRQRVAVDMTGRSTAGRMIGEDVAMPVALAPVGS
TGMQHADGEILAAQAAEAFGVPFTLSTMSICSIEDVAANTSKPFWFQLYAMKDKRFVERVIQRAKDAKCSALVLTLDLQI
LGQRHKDIKNGLSIPIKPTVPNLIDLATKWRWIAAMAKTKRRQFGNIVGHIEGISDMTSLSIWAAESFDPKLNWDEVKEI
KKMWGGPLILKGILDAEDARMALNVGADAIVVSNHGGRQLDGALSSIRALPAILDAVGDKVEVHMDGGIRSGQDVLKALA
LGAKGTYIGRAFVHGLGAMGGPGVTKALEIIHKELDTTMALCGETDVADLGRHNLLVPKDFEGQWQSP

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=369, Percent_Identity=34.4173441734417, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI54234014, Length=373, Percent_Identity=35.1206434316354, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI7705393, Length=373, Percent_Identity=35.1206434316354, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1790033, Length=376, Percent_Identity=40.4255319148936, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI193208036, Length=373, Percent_Identity=33.7801608579088, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI32566217, Length=290, Percent_Identity=31.7241379310345, Blast_Score=144, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6323587, Length=379, Percent_Identity=31.6622691292876, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI78707188, Length=370, Percent_Identity=35.9459459459459, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281363140, Length=370, Percent_Identity=35.9459459459459, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI78707190, Length=370, Percent_Identity=35.9459459459459, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42398; Mature: 42267

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITTIQDLKDLHERRVPRMFYDYAESGSWTEQTFHENTTDFAKIRLRQRVAVDMTGRS
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEEEECCCC
TAGRMIGEDVAMPVALAPVGSTGMQHADGEILAAQAAEAFGVPFTLSTMSICSIEDVAAN
HHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEHHHHHHHCCCEEECHHHHHCHHHHHCC
TSKPFWFQLYAMKDKRFVERVIQRAKDAKCSALVLTLDLQILGQRHKDIKNGLSIPIKPT
CCCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCC
VPNLIDLATKWRWIAAMAKTKRRQFGNIVGHIEGISDMTSLSIWAAESFDPKLNWDEVKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCCHHHHHH
IKKMWGGPLILKGILDAEDARMALNVGADAIVVSNHGGRQLDGALSSIRALPAILDAVGD
HHHHCCCCEEEHHHCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
KVEVHMDGGIRSGQDVLKALALGAKGTYIGRAFVHGLGAMGGPGVTKALEIIHKELDTTM
EEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALCGETDVADLGRHNLLVPKDFEGQWQSP
HHCCCCCHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAITTIQDLKDLHERRVPRMFYDYAESGSWTEQTFHENTTDFAKIRLRQRVAVDMTGRS
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHEEEECCCC
TAGRMIGEDVAMPVALAPVGSTGMQHADGEILAAQAAEAFGVPFTLSTMSICSIEDVAAN
HHHHHHHHHHCCCEEEECCCCCCCCCCCCCEEEHHHHHHHCCCEEECHHHHHCHHHHHCC
TSKPFWFQLYAMKDKRFVERVIQRAKDAKCSALVLTLDLQILGQRHKDIKNGLSIPIKPT
CCCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCC
VPNLIDLATKWRWIAAMAKTKRRQFGNIVGHIEGISDMTSLSIWAAESFDPKLNWDEVKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEECCCCCCCCHHHHHH
IKKMWGGPLILKGILDAEDARMALNVGADAIVVSNHGGRQLDGALSSIRALPAILDAVGD
HHHHCCCCEEEHHHCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
KVEVHMDGGIRSGQDVLKALALGAKGTYIGRAFVHGLGAMGGPGVTKALEIIHKELDTTM
EEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALCGETDVADLGRHNLLVPKDFEGQWQSP
HHCCCCCHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA