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The map label for this gene is hutI

Identifier: 110680829

GI number: 110680829

Start: 3543499

End: 3544692

Strand: Direct

Name: hutI

Synonym: RD1_3677

Alternate gene names: 110680829

Gene position: 3543499-3544692 (Clockwise)

Preceding gene: 110680826

Following gene: 110680830

Centisome position: 85.73

GC content: 62.9

Gene sequence:

>1194_bases
ATGCTTTTCACCAACGCCAGAATTGTGACCCTGCGGGACGATCAGGACTACGGTCTGATCGAGGAAGGTGCCATCGCCAC
TGATGGTGACCAGATCGCCTGGGTGGGGCCAAGTGCCGATGTGCCTGATGCTTATCGCAGCGAAACAACGCATGATCTGG
GCGGGCGGCTGGTCACACCGGCGCTGATCGACTGTCACACGCATGTGGTTTTCGGCGGCAATCGCGCGACCGAATTCGAG
CTGCGCCTGAACGGTGCGAGCTACGAAGAAGTGGCGCGCGCAGGCGGGGGAATCGTATCGACCGTGACGGCCACGCGCGG
CGCATCCGAGGCGGCGCTGCTGGCCGATGCGCTGACCCGAGTAGATGCACTGATCGCGGAAGGTGTCACGCTGATCGAGG
TGAAATCCGGCTACGGGCTGGACCGCGACACGGAACTCAAGATGCTGCGCGTCGCCCGCCAGATCGCAAGCGCCCGCCCG
GTAGATGTGCGCACCAGCTTTCTCGGTGCGCATGCTGTCCCGCCGGAATTCAAGGGCAACCCGGACGCCTATATCGACGA
CATCTGTATTCCGACCCTGCATGCCGCACATGCCGAGGGGCTGGTCGACGCGGTTGACGGTTTCTGCGAGGGCATCGCCT
TTGACACGGCGCAAATCTCGCGCGTTTTTGACGTGGCGGGGGAGCTTGGCCTGCCGATCAAACTCCATGCTGAGCAATTG
TCAAACATCGGCGGCACGCAACTGGCGGCGCGCTATGGCGCGCTGAGCGCGGATCACGTGGAATATGCCACGGATGCCGA
CGCGCAGGCGCTCGCGAAATCCGGCACGGTTGCGGTCGTGCTGCCCGGCGCATTCTATACGCTGCGCGAAACGCAGGTCC
CGCCGATCGCGTCTTTCCGCAAGCACGCTGTACGCATGGCGCTTGCCACGGATTGCAACCCCGGATCATCGCCACTGACA
TCGCCACTTCTGGCGATGAACATGGCCTGCACCCTGTTTCGCATGACCCCGCTGGAAGCCTTGCTGGGAATGACGGCCCA
TGCTGCCGCTGCTTTGGGTGAACAAGATCGCGGCCGGATCATGGCAGGTGCGCGCGCCGATCTGTGCGTCTGGAACGCGC
AGCATCCAAGCGAATTGGCTTATCGCATCGGGTTCAACCCGCTGCATCAGCGCATCTTCAAGGGGGCGATATGA

Upstream 100 bases:

>100_bases
CCTTTTCAGCCCAAATCCTTTGCATGGTTCACTCCGCTTGACATAATATTATGTATGCACATAAAACACCAAGAACGCCA
ACTTGCAAGTGAGTCGACGG

Downstream 100 bases:

>100_bases
CACTCACGCTGACACCGGGTGCGGCAACGCTCGCGCAATTGCAGGATATCTGGGCGAACAATCGCGCTGTCACACTGTGC
CCCTCGGCCCATGCCGGGAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTPALIDCHTHVVFGGNRATEFE
LRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTRVDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARP
VDVRTSFLGAHAVPPEFKGNPDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQL
SNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFRKHAVRMALATDCNPGSSPLT
SPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRIMAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI

Sequences:

>Translated_397_residues
MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTPALIDCHTHVVFGGNRATEFE
LRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTRVDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARP
VDVRTSFLGAHAVPPEFKGNPDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQL
SNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFRKHAVRMALATDCNPGSSPLT
SPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRIMAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI
>Mature_397_residues
MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTPALIDCHTHVVFGGNRATEFE
LRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTRVDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARP
VDVRTSFLGAHAVPPEFKGNPDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQL
SNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFRKHAVRMALATDCNPGSSPLT
SPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRIMAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=362, Percent_Identity=35.0828729281768, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17555004, Length=353, Percent_Identity=34.5609065155807, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_ROSDO (Q162E3)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683836.1
- ProteinModelPortal:   Q162E3
- SMR:   Q162E3
- STRING:   Q162E3
- GeneID:   4194956
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3677
- NMPDR:   fig|375451.6.peg.3420
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   RDEN375451:RD1_3677-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF07969 Amidohydro_3; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 42085; Mature: 42085

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: BINDING 75-75 BINDING 88-88 BINDING 138-138 BINDING 171-171 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTP
CEEECEEEEEEECCCCCCCEECCCEECCCCEEEEECCCCCCCHHHHCCCCHHCCCEECCC
ALIDCHTHVVFGGNRATEFELRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTR
HHEECEEEEEECCCCCEEEEEEECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
VDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARPVDVRTSFLGAHAVPPEFKGN
HHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCC
PDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQL
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
SNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFR
CCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHH
KHAVRMALATDCNPGSSPLTSPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRI
HHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
MAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI
EECCCCCEEEECCCCHHHHHEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MLFTNARIVTLRDDQDYGLIEEGAIATDGDQIAWVGPSADVPDAYRSETTHDLGGRLVTP
CEEECEEEEEEECCCCCCCEECCCEECCCCEEEEECCCCCCCHHHHCCCCHHCCCEECCC
ALIDCHTHVVFGGNRATEFELRLNGASYEEVARAGGGIVSTVTATRGASEAALLADALTR
HHEECEEEEEECCCCCEEEEEEECCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
VDALIAEGVTLIEVKSGYGLDRDTELKMLRVARQIASARPVDVRTSFLGAHAVPPEFKGN
HHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCC
PDAYIDDICIPTLHAAHAEGLVDAVDGFCEGIAFDTAQISRVFDVAGELGLPIKLHAEQL
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHH
SNIGGTQLAARYGALSADHVEYATDADAQALAKSGTVAVVLPGAFYTLRETQVPPIASFR
CCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHH
KHAVRMALATDCNPGSSPLTSPLLAMNMACTLFRMTPLEALLGMTAHAAAALGEQDRGRI
HHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCE
MAGARADLCVWNAQHPSELAYRIGFNPLHQRIFKGAI
EECCCCCEEEECCCCHHHHHEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA