Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 110680657

GI number: 110680657

Start: 3362618

End: 3363241

Strand: Direct

Name: tdk [H]

Synonym: RD1_3494

Alternate gene names: 110680657

Gene position: 3362618-3363241 (Clockwise)

Preceding gene: 110680655

Following gene: 110680663

Centisome position: 81.36

GC content: 58.97

Gene sequence:

>624_bases
TTGCTCTATTGCGGCGCGAACCGGCACGGCCTATCAAACCGCATGGCCAAGCTTTACTTCAACTACTCCACAATGAACGC
CGGAAAGTCGACCGTTCTGTTACAGGCCGCGCACAACTATAAAGAGCGCGGCATGGTGCCGTTCCTGATCACAGCACAGG
TGGATGACCGGGCCGGCGACGGTCGTATTGCATCGCGCATCGGCATCGGTGAGCCGGCGGACACCTTCACGAGCGGAGAA
GACCTTTTTTCCAAGATCGACAATCGGTTGAAGGAAGGCCCGGTCGCATGCGTTTTTGTGGATGAGGCGCAATTTCTCAG
CACGGAACAGGTATGGCAACTGGCGCGCGCGGTGGATGATCTGGGTGTGCCGGTCATGTGCTTTGGGCTGCGGGTGGATT
TTCGCGGAAAACTCTTTCCAGGGTCGGCCACATTGCTGGCGCTGGCCGATGAAATGCGCGAGGTGCGCACCATTTGCCAT
TGCGGCAAGAAAGCCAGCATGGTCATCCGCAAAGACGAAAACGGGACCGTGTTGCGCGATGGCGCGCAAATACAGGTCGG
CGGCAACGAGACTTATGTATCGCTCTGCCGCCGCCATTGGCGCGAAGCCGCCGGCGACCGTTAG

Upstream 100 bases:

>100_bases
CCCAACGCCGGTTTTGGTGAGGCCGAATGTGTGCCAGCGTTTTGGGGAACGGTGGGTCAGCGCCCGCTGACAGCCACACA
TTGGCCTTTTTACCGCTGCT

Downstream 100 bases:

>100_bases
ACCGCGTTGGGCAACGGGGTCCCGGCGAAAAACGCCTTGAGGTTATCCACGCTCATCAGCCCCATGTCCTCGCGCACTTC
AAGCGCCGCCGTGCCGAGAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLYCGANRHGLSNRMAKLYFNYSTMNAGKSTVLLQAAHNYKERGMVPFLITAQVDDRAGDGRIASRIGIGEPADTFTSGE
DLFSKIDNRLKEGPVACVFVDEAQFLSTEQVWQLARAVDDLGVPVMCFGLRVDFRGKLFPGSATLLALADEMREVRTICH
CGKKASMVIRKDENGTVLRDGAQIQVGGNETYVSLCRRHWREAAGDR

Sequences:

>Translated_207_residues
MLYCGANRHGLSNRMAKLYFNYSTMNAGKSTVLLQAAHNYKERGMVPFLITAQVDDRAGDGRIASRIGIGEPADTFTSGE
DLFSKIDNRLKEGPVACVFVDEAQFLSTEQVWQLARAVDDLGVPVMCFGLRVDFRGKLFPGSATLLALADEMREVRTICH
CGKKASMVIRKDENGTVLRDGAQIQVGGNETYVSLCRRHWREAAGDR
>Mature_207_residues
MLYCGANRHGLSNRMAKLYFNYSTMNAGKSTVLLQAAHNYKERGMVPFLITAQVDDRAGDGRIASRIGIGEPADTFTSGE
DLFSKIDNRLKEGPVACVFVDEAQFLSTEQVWQLARAVDDLGVPVMCFGLRVDFRGKLFPGSATLLALADEMREVRTICH
CGKKASMVIRKDENGTVLRDGAQIQVGGNETYVSLCRRHWREAAGDR

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=189, Percent_Identity=52.9100529100529, Blast_Score=226, Evalue=9e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22881; Mature: 22881

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYCGANRHGLSNRMAKLYFNYSTMNAGKSTVLLQAAHNYKERGMVPFLITAQVDDRAGD
CEEECCCCCCHHHHHEEEEEEEEECCCCCCEEEEEEHHCHHHCCCCEEEEEEEECCCCCC
GRIASRIGIGEPADTFTSGEDLFSKIDNRLKEGPVACVFVDEAQFLSTEQVWQLARAVDD
CCEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHCCHHHHHHHHHHHHH
LGVPVMCFGLRVDFRGKLFPGSATLLALADEMREVRTICHCGKKASMVIRKDENGTVLRD
CCCCEEEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEC
GAQIQVGGNETYVSLCRRHWREAAGDR
CCEEEECCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYCGANRHGLSNRMAKLYFNYSTMNAGKSTVLLQAAHNYKERGMVPFLITAQVDDRAGD
CEEECCCCCCHHHHHEEEEEEEEECCCCCCEEEEEEHHCHHHCCCCEEEEEEEECCCCCC
GRIASRIGIGEPADTFTSGEDLFSKIDNRLKEGPVACVFVDEAQFLSTEQVWQLARAVDD
CCEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHCCHHHHHHHHHHHHH
LGVPVMCFGLRVDFRGKLFPGSATLLALADEMREVRTICHCGKKASMVIRKDENGTVLRD
CCCCEEEEEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEC
GAQIQVGGNETYVSLCRRHWREAAGDR
CCEEEECCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA