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The map label for this gene is pyc [H]

Identifier: 110680549

GI number: 110680549

Start: 3241747

End: 3245187

Strand: Direct

Name: pyc [H]

Synonym: RD1_3376

Alternate gene names: 110680549

Gene position: 3241747-3245187 (Clockwise)

Preceding gene: 110680548

Following gene: 110680550

Centisome position: 78.43

GC content: 60.07

Gene sequence:

>3441_bases
ATGCCAGAATTCAAAAAAATCCTCATTGCCAACCGGGGCGAAATCGCGATCCGCATCATGCGCGCAGCAAACGAGATGGG
CAAGAAAACCGTCGCCGTGTTTGCCGAAGAGGATAAACTGGGCCTGCATCGTTTCAAAGCGGATGAGGCCTATCGGATTG
GCGAAGGTTTGGGGCCGGTTGCTGCCTACCTCAGCATTGACGAGATCATCCGTGTGGCAAAGGAATCGGGCGCCGATGCC
ATTCACCCGGGCTATGGGCTGCTCTCCGAGAACCCGGATTTTGTGGACGCCTGCGATCAGAATGGCATCGTCTTCATCGG
CCCGCGTGCCGAAACAATGCGCGCGCTGGGGGACAAGGCCTCCGCCCGCCGGGTGGCCATTGAAGCAGGTGTGCCGGTGA
TCCCGGCCACCGAAGTGCTGGGCGATGACATGAAGGCGATCAAGGCCGAGGCCAAGGAAATCGGCTATCCGCTGATGCTC
AAGGCATCATGGGGCGGCGGGGGGCGCGGCATGCGCCCGATCCAGCAAGAGGACGAGTTGGAAGAAAAGGTCCTTGAGGG
GCGGCGCGAGGCCGAAGCTGCCTTTGGCAATGGCGAGGGCTATCTGGAAAAGATGATCCTCAAGGCGCGCCATGTGGAGG
TTCAGATTCTGGGCGACAAGCATGGGGACATGTATCACCTGTTTGAACGCGACTGTTCGGTCCAGCGGCGCAACCAAAAG
GTCGTCGAGCGCGCGCCCGCCCCCTATCTGACGGAGGCGCAGCGTGCTGAAGTCTGCAAACTGGGCTATGATATTTGCAA
ACATGTGAATTACGAGTGCGCGGGCACGGTCGAATTCCTGATGGATATGGACGATGGCAAGTTCTACTTCATCGAAGTGA
ACCCGCGCGTACAGGTTGAACATACCGTCACCGAAGAGGTGACCGGCATCGACATCGTGCAGGCGCAGATCCTGATCGCA
GAGGGTAAAACCATCGCCGAGGCCACGGGCAAGCCGACGCAGGCGGATGTGCAACTGAACGGCCATGCGCTGCAGACCCG
GATCACCACCGAGGACCCGCAGAATAACTTCATCCCCGACTATGGCCGCATTACTGCCTTTCGCGAGGCGACGGGCATGG
GCATCCGGCTTGATGGCGGCACTGCCTATTCCGGCGGTGTGATCACGCGCTATTACGACAGCCTGCTGGTCAAGGTCACC
GCCAAAGCGCAAACACCGGACGCGGCCATCGCCCGGATGGACCGTGCCCTGCGCGAATTCCGCATCCGGAGCGTGTCCAC
CAACATCGCCTTTGTCGAGAACCTGCTCAAACACCCGACGTTTCTGAACAATGAATATCACACCAAATTCATTGACGAGA
CGCCCGACCTGTTCCAATTCTCCAAGCGGCGCGATCGTGGCACCAAAGTGCTGACCTATATCGCCGATATCACCGTGAAC
GGCCATCCCGAAACCAAGGCCCATCCGCGCCCGCCGGCCCATGTCAAAGACCCCCGCCCCCCCAAGGAACGCGCGGAACC
CATGATGGGCACGCGCAACCTGCTGGAACAGAAGGGCCCGCAGGCGGTTGCCGACTGGATGAAGCAACAGCGTCAGCTCT
TGATCACCGACACCACCATGCGCGACGGGCACCAGTCGCTGCTGGCCACGCGGATGCGGTCCATTGATATGATCAAGGTG
GCGCCGAGCTATTCGGCCAACCTGCCGCAACTCTTTTCCGTTGAATGTTGGGGGGGCGCGACCTTCGATGTGGCCTATCG
CTTCCTGCAGGAATGCCCCTGGCAGCGCCTGCGCGATTTGCGTTCCGCCATGCCGAACCTGATGACGCAGATGCTACTGC
GCGCCTCAAACGGGGTGGGATATACCAATTACCCGGATAATGTGGTGCAGGAATTCGTGCGCGTCGCCGCCAAGACCGGG
GTGGATGTGTTCCGCGTCTTTGACAGCCTCAACTGGGTTGAGAACATGCGCGTTGCGATGGATGCCGTGATCGAGAACGG
CAAGGTCTGCGAAGGGTCCATCTGCTACACTGGCGACATCAATGACCCGGATCGGGCAAAGTATAACCTGAAATATTATG
TCGACATGGGCAAGGAACTGCGCGACGCGGGGGCCCATGTGCTTGGCCTCAAGGATATGGCGGGCCTGCTCAAACCCGCC
GCCGCGCGCCAGTTGGTCCGCACCCTGAAATCCGAAGTCGGCCTGCCGATCCATTTTCACACCCATGATACCGCCGGCGT
GGCCTGTGCCACAATCCTTGCTGCCTCCGAGGCGGGTGTGGATGCGGTGGACTGCGCGATGGATGCGCTGTCGGGCAACA
CCTCGCAGGCGACGCTGGGCTCTGTTGTTTCGGCACTGAAACACACCGACCGCGACACCGGGCTGGATATGTCCGCGATT
CGCGAAATTTCCGATTATTGGGAAGAGGTGCGCAATCACTACGCCGCCTTTGAAACCGGCATGCAGGCGCCCTCCTCCGA
GGTTTATCTGCATGAAATGCCCGGCGGCCAGTTCACCAACCTCAAGGCGCAGGCGGCGAGCCTTGGGCTTGCGGATCGCT
GGCACGAGGTCGCACAAACCTATGCCGAGGTGAACCAGATGTTTGGCGATATCGTCAAGGTGACGCCATCCTCCAAGGTG
GTGGGCGATATGGCCCTGATGATGGTATCGCAAGGGCTGAGCCGGGCCGACGTGGAAAACCCGGACACAGATGTCTCCTT
CCCGGACAGTGTCGTGGATATGATGCGCGGCAACCTCGGCCAACCGCCCGGCGGTTTTCCCGAGGCCATTGTGAAAAAGG
TGCTCAAGGATGAACAACCGATCCTTGACCGCCCCGGCAAACACCTGCCCCCCGCCGATCTCGAAGCCCTGCGCGCAGAA
GCCTCCAATCTGATGGAAGGCAAGCTCGTTGATGATGAGGACTTGTCGGGATATCTGATGTATCCCAAGGTGTTCCTAGA
TTATATGGGCCGCCATCGCACCTATGGGCCGGTCCGGGCGCTGCCCACCAAGACGTTCTTTTACGGCATGGAACCGGGCG
AAGAAATCAGCGCGGAAATCGACCCCGGTAAGACGCTCGAAATTCGTCTGCAGACGGTCGGCGACACGGGTGAAGACGGT
GAGGTCCGGGTGTTCTTTGAGCTTAACGGCCAGCCCCGCGTGATCCGCGTGCCCAACCGCCTCGTAACGGCAAGCACGCA
AAAACGCCCCAAAGCCGAGACCGGCAACGCCAAACATATCGGCGCGCCCATGCCGGGTGTTGTTGCCTCCGTTGCGGCCA
AGGAGGGCGGCAAGGTCAAGGCGGGTGATCTGTTGCTCACCATTGAAGCGATGAAAATGGAGACCGGTATCCACGCCGAA
AAGGCCGCCACTGTCAAAGCCGTACACGTCAGCCCCGGCGGCCAGATTGATGCCAAGGACCTGCTGATCGAGTTTGAATA
A

Upstream 100 bases:

>100_bases
CTGCACTGCGGCAGTTCGCGGGCCATCCGTTCGTACGCGTTTACGCCACGTGTAAATCCGCCTAGACAGTTGACGAGACC
GCCAAACCCAAGAGAGTCAC

Downstream 100 bases:

>100_bases
CATCTGGAAAGGGTCGGCCTGAACGCCGGCACTATTCCCTTATTACGCGAAAAGCCGCCTCGGAATTGTCAACTTTTGTT
GACACAGATCAAGGATCATC

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1146; Mature: 1145

Protein sequence:

>1146_residues
MPEFKKILIANRGEIAIRIMRAANEMGKKTVAVFAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKESGADA
IHPGYGLLSENPDFVDACDQNGIVFIGPRAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMKAIKAEAKEIGYPLML
KASWGGGGRGMRPIQQEDELEEKVLEGRREAEAAFGNGEGYLEKMILKARHVEVQILGDKHGDMYHLFERDCSVQRRNQK
VVERAPAPYLTEAQRAEVCKLGYDICKHVNYECAGTVEFLMDMDDGKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIA
EGKTIAEATGKPTQADVQLNGHALQTRITTEDPQNNFIPDYGRITAFREATGMGIRLDGGTAYSGGVITRYYDSLLVKVT
AKAQTPDAAIARMDRALREFRIRSVSTNIAFVENLLKHPTFLNNEYHTKFIDETPDLFQFSKRRDRGTKVLTYIADITVN
GHPETKAHPRPPAHVKDPRPPKERAEPMMGTRNLLEQKGPQAVADWMKQQRQLLITDTTMRDGHQSLLATRMRSIDMIKV
APSYSANLPQLFSVECWGGATFDVAYRFLQECPWQRLRDLRSAMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRVAAKTG
VDVFRVFDSLNWVENMRVAMDAVIENGKVCEGSICYTGDINDPDRAKYNLKYYVDMGKELRDAGAHVLGLKDMAGLLKPA
AARQLVRTLKSEVGLPIHFHTHDTAGVACATILAASEAGVDAVDCAMDALSGNTSQATLGSVVSALKHTDRDTGLDMSAI
REISDYWEEVRNHYAAFETGMQAPSSEVYLHEMPGGQFTNLKAQAASLGLADRWHEVAQTYAEVNQMFGDIVKVTPSSKV
VGDMALMMVSQGLSRADVENPDTDVSFPDSVVDMMRGNLGQPPGGFPEAIVKKVLKDEQPILDRPGKHLPPADLEALRAE
ASNLMEGKLVDDEDLSGYLMYPKVFLDYMGRHRTYGPVRALPTKTFFYGMEPGEEISAEIDPGKTLEIRLQTVGDTGEDG
EVRVFFELNGQPRVIRVPNRLVTASTQKRPKAETGNAKHIGAPMPGVVASVAAKEGGKVKAGDLLLTIEAMKMETGIHAE
KAATVKAVHVSPGGQIDAKDLLIEFE

Sequences:

>Translated_1146_residues
MPEFKKILIANRGEIAIRIMRAANEMGKKTVAVFAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKESGADA
IHPGYGLLSENPDFVDACDQNGIVFIGPRAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMKAIKAEAKEIGYPLML
KASWGGGGRGMRPIQQEDELEEKVLEGRREAEAAFGNGEGYLEKMILKARHVEVQILGDKHGDMYHLFERDCSVQRRNQK
VVERAPAPYLTEAQRAEVCKLGYDICKHVNYECAGTVEFLMDMDDGKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIA
EGKTIAEATGKPTQADVQLNGHALQTRITTEDPQNNFIPDYGRITAFREATGMGIRLDGGTAYSGGVITRYYDSLLVKVT
AKAQTPDAAIARMDRALREFRIRSVSTNIAFVENLLKHPTFLNNEYHTKFIDETPDLFQFSKRRDRGTKVLTYIADITVN
GHPETKAHPRPPAHVKDPRPPKERAEPMMGTRNLLEQKGPQAVADWMKQQRQLLITDTTMRDGHQSLLATRMRSIDMIKV
APSYSANLPQLFSVECWGGATFDVAYRFLQECPWQRLRDLRSAMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRVAAKTG
VDVFRVFDSLNWVENMRVAMDAVIENGKVCEGSICYTGDINDPDRAKYNLKYYVDMGKELRDAGAHVLGLKDMAGLLKPA
AARQLVRTLKSEVGLPIHFHTHDTAGVACATILAASEAGVDAVDCAMDALSGNTSQATLGSVVSALKHTDRDTGLDMSAI
REISDYWEEVRNHYAAFETGMQAPSSEVYLHEMPGGQFTNLKAQAASLGLADRWHEVAQTYAEVNQMFGDIVKVTPSSKV
VGDMALMMVSQGLSRADVENPDTDVSFPDSVVDMMRGNLGQPPGGFPEAIVKKVLKDEQPILDRPGKHLPPADLEALRAE
ASNLMEGKLVDDEDLSGYLMYPKVFLDYMGRHRTYGPVRALPTKTFFYGMEPGEEISAEIDPGKTLEIRLQTVGDTGEDG
EVRVFFELNGQPRVIRVPNRLVTASTQKRPKAETGNAKHIGAPMPGVVASVAAKEGGKVKAGDLLLTIEAMKMETGIHAE
KAATVKAVHVSPGGQIDAKDLLIEFE
>Mature_1145_residues
PEFKKILIANRGEIAIRIMRAANEMGKKTVAVFAEEDKLGLHRFKADEAYRIGEGLGPVAAYLSIDEIIRVAKESGADAI
HPGYGLLSENPDFVDACDQNGIVFIGPRAETMRALGDKASARRVAIEAGVPVIPATEVLGDDMKAIKAEAKEIGYPLMLK
ASWGGGGRGMRPIQQEDELEEKVLEGRREAEAAFGNGEGYLEKMILKARHVEVQILGDKHGDMYHLFERDCSVQRRNQKV
VERAPAPYLTEAQRAEVCKLGYDICKHVNYECAGTVEFLMDMDDGKFYFIEVNPRVQVEHTVTEEVTGIDIVQAQILIAE
GKTIAEATGKPTQADVQLNGHALQTRITTEDPQNNFIPDYGRITAFREATGMGIRLDGGTAYSGGVITRYYDSLLVKVTA
KAQTPDAAIARMDRALREFRIRSVSTNIAFVENLLKHPTFLNNEYHTKFIDETPDLFQFSKRRDRGTKVLTYIADITVNG
HPETKAHPRPPAHVKDPRPPKERAEPMMGTRNLLEQKGPQAVADWMKQQRQLLITDTTMRDGHQSLLATRMRSIDMIKVA
PSYSANLPQLFSVECWGGATFDVAYRFLQECPWQRLRDLRSAMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRVAAKTGV
DVFRVFDSLNWVENMRVAMDAVIENGKVCEGSICYTGDINDPDRAKYNLKYYVDMGKELRDAGAHVLGLKDMAGLLKPAA
ARQLVRTLKSEVGLPIHFHTHDTAGVACATILAASEAGVDAVDCAMDALSGNTSQATLGSVVSALKHTDRDTGLDMSAIR
EISDYWEEVRNHYAAFETGMQAPSSEVYLHEMPGGQFTNLKAQAASLGLADRWHEVAQTYAEVNQMFGDIVKVTPSSKVV
GDMALMMVSQGLSRADVENPDTDVSFPDSVVDMMRGNLGQPPGGFPEAIVKKVLKDEQPILDRPGKHLPPADLEALRAEA
SNLMEGKLVDDEDLSGYLMYPKVFLDYMGRHRTYGPVRALPTKTFFYGMEPGEEISAEIDPGKTLEIRLQTVGDTGEDGE
VRVFFELNGQPRVIRVPNRLVTASTQKRPKAETGNAKHIGAPMPGVVASVAAKEGGKVKAGDLLLTIEAMKMETGIHAEK
AATVKAVHVSPGGQIDAKDLLIEFE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1150, Percent_Identity=49.2173913043478, Blast_Score=1078, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1150, Percent_Identity=49.2173913043478, Blast_Score=1078, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1150, Percent_Identity=49.2173913043478, Blast_Score=1078, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=463, Percent_Identity=42.548596112311, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI65506442, Length=461, Percent_Identity=40.997830802603, Blast_Score=325, Evalue=2e-88,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=40.7327586206897, Blast_Score=325, Evalue=2e-88,
Organism=Homo sapiens, GI295821183, Length=461, Percent_Identity=40.997830802603, Blast_Score=324, Evalue=3e-88,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=31.2992125984252, Blast_Score=224, Evalue=5e-58,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=31.2992125984252, Blast_Score=224, Evalue=5e-58,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=31.2992125984252, Blast_Score=224, Evalue=5e-58,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=31.2992125984252, Blast_Score=223, Evalue=6e-58,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=31.2992125984252, Blast_Score=223, Evalue=7e-58,
Organism=Homo sapiens, GI134142062, Length=509, Percent_Identity=31.8271119842829, Blast_Score=219, Evalue=9e-57,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=44.7661469933185, Blast_Score=347, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17562816, Length=1150, Percent_Identity=50.0869565217391, Blast_Score=1118, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=458, Percent_Identity=44.1048034934498, Blast_Score=359, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17567343, Length=464, Percent_Identity=40.948275862069, Blast_Score=322, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI133931226, Length=497, Percent_Identity=30.9859154929577, Blast_Score=217, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=31.1363636363636, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71997168, Length=513, Percent_Identity=29.4346978557505, Blast_Score=204, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1160, Percent_Identity=46.3793103448276, Blast_Score=1026, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1160, Percent_Identity=46.8103448275862, Blast_Score=1011, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=451, Percent_Identity=38.8026607538803, Blast_Score=320, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=31.4453125, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323863, Length=439, Percent_Identity=33.2574031890661, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24652212, Length=1153, Percent_Identity=48.2220294882914, Blast_Score=1068, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1153, Percent_Identity=48.2220294882914, Blast_Score=1068, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1153, Percent_Identity=48.2220294882914, Blast_Score=1068, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1153, Percent_Identity=48.2220294882914, Blast_Score=1068, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1153, Percent_Identity=48.2220294882914, Blast_Score=1068, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1168, Percent_Identity=47.5171232876712, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1168, Percent_Identity=47.5171232876712, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1168, Percent_Identity=47.5171232876712, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1168, Percent_Identity=47.5171232876712, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1168, Percent_Identity=47.5171232876712, Blast_Score=1065, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=456, Percent_Identity=40.7894736842105, Blast_Score=352, Evalue=9e-97,
Organism=Drosophila melanogaster, GI24651759, Length=418, Percent_Identity=39.7129186602871, Blast_Score=311, Evalue=2e-84,
Organism=Drosophila melanogaster, GI161076409, Length=516, Percent_Identity=31.0077519379845, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161076407, Length=516, Percent_Identity=31.0077519379845, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586460, Length=516, Percent_Identity=31.0077519379845, Blast_Score=208, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24586458, Length=516, Percent_Identity=31.0077519379845, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126214; Mature: 126082

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEFKKILIANRGEIAIRIMRAANEMGKKTVAVFAEEDKLGLHRFKADEAYRIGEGLGPV
CCCHHEEEEECCCCEEEHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCHHHHCCCCCHH
AAYLSIDEIIRVAKESGADAIHPGYGLLSENPDFVDACDQNGIVFIGPRAETMRALGDKA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHCCCC
SARRVAIEAGVPVIPATEVLGDDMKAIKAEAKEIGYPLMLKASWGGGGRGMRPIQQEDEL
CCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHH
EEKVLEGRREAEAAFGNGEGYLEKMILKARHVEVQILGDKHGDMYHLFERDCSVQRRNQK
HHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHCCHHHHHHHH
VVERAPAPYLTEAQRAEVCKLGYDICKHVNYECAGTVEFLMDMDDGKFYFIEVNPRVQVE
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCEEEEE
HTVTEEVTGIDIVQAQILIAEGKTIAEATGKPTQADVQLNGHALQTRITTEDPQNNFIPD
EEHHHHHCCCEEEEEEEEEECCCEEECCCCCCCEEEEEECCEEEEEEEECCCCCCCCCCC
YGRITAFREATGMGIRLDGGTAYSGGVITRYYDSLLVKVTAKAQTPDAAIARMDRALREF
CHHEEEEHHHCCCEEEECCCCEECCCHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHH
RIRSVSTNIAFVENLLKHPTFLNNEYHTKFIDETPDLFQFSKRRDRGTKVLTYIADITVN
HHHHHCCHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEEEEEEEEC
GHPETKAHPRPPAHVKDPRPPKERAEPMMGTRNLLEQKGPQAVADWMKQQRQLLITDTTM
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCC
RDGHQSLLATRMRSIDMIKVAPSYSANLPQLFSVECWGGATFDVAYRFLQECPWQRLRDL
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHH
RSAMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRVAAKTGVDVFRVFDSLNWVENMRVAM
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAVIENGKVCEGSICYTGDINDPDRAKYNLKYYVDMGKELRDAGAHVLGLKDMAGLLKPA
HHHHCCCCEECCCEEEECCCCCCCCCEEEEEEEEECCHHHHHCCCEEEEHHHHHHHHCHH
AARQLVRTLKSEVGLPIHFHTHDTAGVACATILAASEAGVDAVDCAMDALSGNTSQATLG
HHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
SVVSALKHTDRDTGLDMSAIREISDYWEEVRNHYAAFETGMQAPSSEVYLHEMPGGQFTN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
LKAQAASLGLADRWHEVAQTYAEVNQMFGDIVKVTPSSKVVGDMALMMVSQGLSRADVEN
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCCC
PDTDVSFPDSVVDMMRGNLGQPPGGFPEAIVKKVLKDEQPILDRPGKHLPPADLEALRAE
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
ASNLMEGKLVDDEDLSGYLMYPKVFLDYMGRHRTYGPVRALPTKTFFYGMEPGEEISAEI
HHHHCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DPGKTLEIRLQTVGDTGEDGEVRVFFELNGQPRVIRVPNRLVTASTQKRPKAETGNAKHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCEEEECCCCCCCCCCCCCCCCC
GAPMPGVVASVAAKEGGKVKAGDLLLTIEAMKMETGIHAEKAATVKAVHVSPGGQIDAKD
CCCCCHHHHHHHHCCCCCEEECCEEEEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCHHH
LLIEFE
EEEEEC
>Mature Secondary Structure 
PEFKKILIANRGEIAIRIMRAANEMGKKTVAVFAEEDKLGLHRFKADEAYRIGEGLGPV
CCHHEEEEECCCCEEEHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCHHHHCCCCCHH
AAYLSIDEIIRVAKESGADAIHPGYGLLSENPDFVDACDQNGIVFIGPRAETMRALGDKA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEECCCHHHHHHHCCCC
SARRVAIEAGVPVIPATEVLGDDMKAIKAEAKEIGYPLMLKASWGGGGRGMRPIQQEDEL
CCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHH
EEKVLEGRREAEAAFGNGEGYLEKMILKARHVEVQILGDKHGDMYHLFERDCSVQRRNQK
HHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHCCHHHHHHHH
VVERAPAPYLTEAQRAEVCKLGYDICKHVNYECAGTVEFLMDMDDGKFYFIEVNPRVQVE
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCEEEEE
HTVTEEVTGIDIVQAQILIAEGKTIAEATGKPTQADVQLNGHALQTRITTEDPQNNFIPD
EEHHHHHCCCEEEEEEEEEECCCEEECCCCCCCEEEEEECCEEEEEEEECCCCCCCCCCC
YGRITAFREATGMGIRLDGGTAYSGGVITRYYDSLLVKVTAKAQTPDAAIARMDRALREF
CHHEEEEHHHCCCEEEECCCCEECCCHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHH
RIRSVSTNIAFVENLLKHPTFLNNEYHTKFIDETPDLFQFSKRRDRGTKVLTYIADITVN
HHHHHCCHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEEEEEEEEC
GHPETKAHPRPPAHVKDPRPPKERAEPMMGTRNLLEQKGPQAVADWMKQQRQLLITDTTM
CCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCC
RDGHQSLLATRMRSIDMIKVAPSYSANLPQLFSVECWGGATFDVAYRFLQECPWQRLRDL
CCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHH
RSAMPNLMTQMLLRASNGVGYTNYPDNVVQEFVRVAAKTGVDVFRVFDSLNWVENMRVAM
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAVIENGKVCEGSICYTGDINDPDRAKYNLKYYVDMGKELRDAGAHVLGLKDMAGLLKPA
HHHHCCCCEECCCEEEECCCCCCCCCEEEEEEEEECCHHHHHCCCEEEEHHHHHHHHCHH
AARQLVRTLKSEVGLPIHFHTHDTAGVACATILAASEAGVDAVDCAMDALSGNTSQATLG
HHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
SVVSALKHTDRDTGLDMSAIREISDYWEEVRNHYAAFETGMQAPSSEVYLHEMPGGQFTN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
LKAQAASLGLADRWHEVAQTYAEVNQMFGDIVKVTPSSKVVGDMALMMVSQGLSRADVEN
CHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCCC
PDTDVSFPDSVVDMMRGNLGQPPGGFPEAIVKKVLKDEQPILDRPGKHLPPADLEALRAE
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
ASNLMEGKLVDDEDLSGYLMYPKVFLDYMGRHRTYGPVRALPTKTFFYGMEPGEEISAEI
HHHHCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCC
DPGKTLEIRLQTVGDTGEDGEVRVFFELNGQPRVIRVPNRLVTASTQKRPKAETGNAKHI
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCCEEEECCCCCCCCCCCCCCCCC
GAPMPGVVASVAAKEGGKVKAGDLLLTIEAMKMETGIHAEKAATVKAVHVSPGGQIDAKD
CCCCCHHHHHHHHCCCCCEEECCEEEEEEEHHHHCCCCCCCCCEEEEEEECCCCCCCHHH
LLIEFE
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]