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The map label for this gene is lldD [H]

Identifier: 110680548

GI number: 110680548

Start: 3240444

End: 3241601

Strand: Direct

Name: lldD [H]

Synonym: RD1_3375

Alternate gene names: 110680548

Gene position: 3240444-3241601 (Clockwise)

Preceding gene: 110680545

Following gene: 110680549

Centisome position: 78.4

GC content: 64.42

Gene sequence:

>1158_bases
ATGAGCCTGCACAACCGCTATCCCGCGATCGCCGATCTGCGGACCCGCGCCCGCGCCCGTATACCGAAATTCGTGTGGGA
GTATCTCGATTCGGCAACCGGCACCGAGGCCACGCAGCGGCGTAACCGTACTGCATTGGACCGTATTGGCCTGCGCCCCT
CGATCCTGCATGGCGAATTCGCCCCTGATCTGAGCACCGCGTTTCTCGACGTGAAACGCCCGCTGCCGTTCGGGGTCGCA
CCTGTGGGCATGTCCGGGCTGATGTGGCCCGATGCCGAAGGGCATCTGGCCCGCGCAGCGGCGCGCGCACAGATCCCCTA
TTCGCTGTCAACTGTTGCCAGCCAATCCCCCGAAGACGTCGCACCGCATCTTGGCCCGGATGCATGGTTTCAGATGTATC
CACCGCGCGATCCGGATATTCGCACCGATATGCTGGCGCGGGCGCGGGCCGCGGGTTTCGCCACCCTGGTGCTGACGGTG
GATGTGCCCGTCGCCTCGCGCCGCGAGCGGCAGACCCGCTCTGGCCTGACCCAGCCGCCGCGCCTGACACCGCGCCTGTT
GGCGCAGGTTGCCACAAGACCGGCGTGGGCATGGGGAATGGCACAGCGCGGCATGCCCCGCATGCGCGGGCTTGAAAAAT
ACACCCCAAAAACCGAAAACGCCCTGTCCTCGACACAACATGCCGGATATCTGCTGCGCACCTCCCCCGACTGGGACTAT
GTCGCATGGCTGCGCGACGCCTGGGATGGCCCTTTCGTGGTCAAGGGCGTGCTGCGGGCCGAGGATGCAGAGCCGCTGAA
AAAACGCGGTGTTGATGCGATCTGGGTCTCAAATCATGCGGGTCGCCAGTTTGATGCGGCCCCGGCCAGCATTGACGCCC
TGCGCGATATCCGGGCCGCGACCGACCTGCCGCTGATCTTTGACAGCGGCATCGAAGGCGGGCTTGATATTCTGCGCGCC
TATGCGTGTGGTGCGGATTTCGTCATGCTGGGCCGGGCGTTTCATTATGCGCTGGCAGCTCTCGGACCTCTTGGCGTGGA
TCATCTGATTGATATTCTGACCAAGGACATCGAAGCGAACATGGGCCAACTTGGCGCGCGGACGCTGCGCGCGGTGCCAG
TGCCCTTTGATCTGGCCACGGACAGGCCTGCTCTGTGA

Upstream 100 bases:

>100_bases
ACCCTAGCGCGCGATCGCACGGAGATAAAGAGAAGTTCACACTCTGTTCTGCAGCTTTTCCGCTCTGGACAATCCGCTGA
TCTGGCAGGCAAATAGGCGC

Downstream 100 bases:

>100_bases
TGGTCGGGCTGTGCGCTTGGTACTTTACTTTAGGTCGGCGAAATGCTGCACTGCGGCAGTTCGCGGGCCATCCGTTCGTA
CGCGTTTACGCCACGTGTAA

Product: L-lactate dehydrogenase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSLHNRYPAIADLRTRARARIPKFVWEYLDSATGTEATQRRNRTALDRIGLRPSILHGEFAPDLSTAFLDVKRPLPFGVA
PVGMSGLMWPDAEGHLARAAARAQIPYSLSTVASQSPEDVAPHLGPDAWFQMYPPRDPDIRTDMLARARAAGFATLVLTV
DVPVASRRERQTRSGLTQPPRLTPRLLAQVATRPAWAWGMAQRGMPRMRGLEKYTPKTENALSSTQHAGYLLRTSPDWDY
VAWLRDAWDGPFVVKGVLRAEDAEPLKKRGVDAIWVSNHAGRQFDAAPASIDALRDIRAATDLPLIFDSGIEGGLDILRA
YACGADFVMLGRAFHYALAALGPLGVDHLIDILTKDIEANMGQLGARTLRAVPVPFDLATDRPAL

Sequences:

>Translated_385_residues
MSLHNRYPAIADLRTRARARIPKFVWEYLDSATGTEATQRRNRTALDRIGLRPSILHGEFAPDLSTAFLDVKRPLPFGVA
PVGMSGLMWPDAEGHLARAAARAQIPYSLSTVASQSPEDVAPHLGPDAWFQMYPPRDPDIRTDMLARARAAGFATLVLTV
DVPVASRRERQTRSGLTQPPRLTPRLLAQVATRPAWAWGMAQRGMPRMRGLEKYTPKTENALSSTQHAGYLLRTSPDWDY
VAWLRDAWDGPFVVKGVLRAEDAEPLKKRGVDAIWVSNHAGRQFDAAPASIDALRDIRAATDLPLIFDSGIEGGLDILRA
YACGADFVMLGRAFHYALAALGPLGVDHLIDILTKDIEANMGQLGARTLRAVPVPFDLATDRPAL
>Mature_384_residues
SLHNRYPAIADLRTRARARIPKFVWEYLDSATGTEATQRRNRTALDRIGLRPSILHGEFAPDLSTAFLDVKRPLPFGVAP
VGMSGLMWPDAEGHLARAAARAQIPYSLSTVASQSPEDVAPHLGPDAWFQMYPPRDPDIRTDMLARARAAGFATLVLTVD
VPVASRRERQTRSGLTQPPRLTPRLLAQVATRPAWAWGMAQRGMPRMRGLEKYTPKTENALSSTQHAGYLLRTSPDWDYV
AWLRDAWDGPFVVKGVLRAEDAEPLKKRGVDAIWVSNHAGRQFDAAPASIDALRDIRAATDLPLIFDSGIEGGLDILRAY
ACGADFVMLGRAFHYALAALGPLGVDHLIDILTKDIEANMGQLGARTLRAVPVPFDLATDRPAL

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=368, Percent_Identity=31.7934782608696, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI7705393, Length=368, Percent_Identity=31.7934782608696, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI11068137, Length=378, Percent_Identity=29.6296296296296, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI1790033, Length=367, Percent_Identity=38.6920980926431, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI193208036, Length=380, Percent_Identity=30.7894736842105, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI32566217, Length=284, Percent_Identity=30.9859154929577, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6323587, Length=385, Percent_Identity=29.6103896103896, Blast_Score=146, Evalue=6e-36,
Organism=Drosophila melanogaster, GI281363140, Length=365, Percent_Identity=34.7945205479452, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI78707190, Length=365, Percent_Identity=34.7945205479452, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI78707188, Length=365, Percent_Identity=34.7945205479452, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 42308; Mature: 42177

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHNRYPAIADLRTRARARIPKFVWEYLDSATGTEATQRRNRTALDRIGLRPSILHGEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
APDLSTAFLDVKRPLPFGVAPVGMSGLMWPDAEGHLARAAARAQIPYSLSTVASQSPEDV
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHC
APHLGPDAWFQMYPPRDPDIRTDMLARARAAGFATLVLTVDVPVASRRERQTRSGLTQPP
CCCCCCCHHEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCCC
RLTPRLLAQVATRPAWAWGMAQRGMPRMRGLEKYTPKTENALSSTQHAGYLLRTSPDWDY
CCCHHHHHHHHHCCHHHHHHHHCCCHHHHCHHHCCCCHHHHHHHHHHCCEEEECCCCCHH
VAWLRDAWDGPFVVKGVLRAEDAEPLKKRGVDAIWVSNHAGRQFDAAPASIDALRDIRAA
HHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
TDLPLIFDSGIEGGLDILRAYACGADFVMLGRAFHYALAALGPLGVDHLIDILTKDIEAN
CCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
MGQLGARTLRAVPVPFDLATDRPAL
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLHNRYPAIADLRTRARARIPKFVWEYLDSATGTEATQRRNRTALDRIGLRPSILHGEF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCC
APDLSTAFLDVKRPLPFGVAPVGMSGLMWPDAEGHLARAAARAQIPYSLSTVASQSPEDV
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHC
APHLGPDAWFQMYPPRDPDIRTDMLARARAAGFATLVLTVDVPVASRRERQTRSGLTQPP
CCCCCCCHHEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCCCC
RLTPRLLAQVATRPAWAWGMAQRGMPRMRGLEKYTPKTENALSSTQHAGYLLRTSPDWDY
CCCHHHHHHHHHCCHHHHHHHHCCCHHHHCHHHCCCCHHHHHHHHHHCCEEEECCCCCHH
VAWLRDAWDGPFVVKGVLRAEDAEPLKKRGVDAIWVSNHAGRQFDAAPASIDALRDIRAA
HHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
TDLPLIFDSGIEGGLDILRAYACGADFVMLGRAFHYALAALGPLGVDHLIDILTKDIEAN
CCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
MGQLGARTLRAVPVPFDLATDRPAL
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA