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The map label for this gene is ppiD [H]

Identifier: 110680386

GI number: 110680386

Start: 3067420

End: 3069258

Strand: Direct

Name: ppiD [H]

Synonym: RD1_3203

Alternate gene names: 110680386

Gene position: 3067420-3069258 (Clockwise)

Preceding gene: 110680385

Following gene: 110680387

Centisome position: 74.22

GC content: 62.43

Gene sequence:

>1839_bases
ATGATCAAAGGTTTCAGCCTCTCCAAGACGGCAATCTGGATTTTGATGGGTCTGTTGATCCTTGGCCTCGCCGGGTTCGG
GGCCACGAATATGTCGGGCAACATCCGCACCATCGGGACTGCCGGGGACAAACCGATCCCGGTCGATGATTATTTCCGCC
AGTTGCAGCAGGAAATCCGCGCGGTGGAACAGCAAACCCGCGAGGTGCTGCCCTTCCAGCAGGCGCAGCAGATGGGTCTG
GACCGCGCCGTGCTGCAGCGGCTTGTCGCGACGCGCTCGCTGGATCACGAAACATCGCAACTGGGCCTGTCCATTGGCGA
TGAGGAATTGCGCAGGCGCATTCTGGACATCAGCGCCTTTCAGGGGATCAACGGCGAATTTGACCGCGAGGGATACCGCT
TTGCGCTGGAGCAGACCGGCCTGAGCGAAGCGGAATTCGAAACGCAACTGCGCGAAGAAGTGGCGCGCACCATCGTTCAG
GGCGCGGTTCTGGGCGGGATCGCGATGCCCGAAACATATGTGGACACCTTGGTGAATTACATCGGCGAGCAGCGCAGTTT
CACGTGGTCGCTGCTGGATGCGAGTGACCTTGCCACGCCTCTGGGCGCGCCGGATGATGCGGTTTTACGTGCGCATTATG
ATGACAACATCGACGTCTTCACGCTGCCCGAAACCAAGCAGATCACCTATGCCTGGCTCACGCCCGATATGCTGCTTGAC
TCGGTGGAGGTCGACGAGGAAGCGCTGCGCGAGGCCTATGCCCAGCAGTCCGCCGAGTTCAACCAGCCCGAACGCCGCCT
TGTCGAGCGCCTCGCGTTTCTGGACAGACAGAGCGCGCAGCAGGCGGCGGATGCGCTGGCGGCGGGCGATTCCTTTGACG
ATCTGGTGCGCGGGCGCGGCCTTGCGCTTGAGGATATTGATCTGGGCGATGTGAGCGAAGCCGAATTGGGCGAGGCCGGC
GCGGGCGTCTTTGCGGCGGATGTGGGCGCGGTTGTCGGCCCCTTTCCGAGCACGCTGGGCCCAGCGCTGTTTCGTGTGAA
CGCCGTCCTTGCCGCCCAGGAAACCCCGTTTGAAGACGCGATCGATCTGCTGCGCCCCCAACTTGCTGCCGATCGCGCCA
GCCGTCTCGTCGCAGCACAGGCAGAGAGTTTTGATGATCTGCTCGCTGCAGGTGCCACCCTCGAAGATCTGGCGTCCGAG
ACGGATATGGTCGTGGCACAGATCGACTGGACCGCACAGAGCACGGAGGAGATCGCCGCCTACCCCACCTTCCGTCAGGC
GGCCGCTGCCGTCGGGCCGCGTGATTTCCCCGAGATCGCGTCACTGGATGATGGCGGGTTGTTCGCGCTGCGCCTCGATA
CGGTTCTGCCGCCCCGCCCCGCCCCCTTTGACGAGATACGCGAAGAGATCATTGCCCATTGGGAAGCCGCCGAGACCGCG
AAACGTCTGGCTGAACAGGTCGCCGCTCAGGTCGGTCTGCTGGAAAACGGCAGCAGCTTTGCCGATCTTGGTCTGGATGC
CATCGTTGAGGAAAACCTGATCCGCTCTGACTTTGTGCCACGCACACCGCCGGGCTTTTTGGAAGACGTGTTCGCCATGG
AAGTGGGCAAGGCGCAGGTCATCGAAAGTGATGCCGCCGTGATCCTTGTGCGGCTCGATGCGGTCGCCCCGCCCGCAGCC
GATGGCGATGCGGCGGCCCTGCGCACGCAGCTTGAGCAACAGGCCAGCCAGCAATTGGCGCGTGACATCTTCGAGGTTTT
CGCAAATGATGTCGTCTTGCGCGCAGACCCGCAGATAAACCAACAGGCGCTGCAAGCGGTGCATGTGAATTTCCCCTGA

Upstream 100 bases:

>100_bases
CGGCGATCTCCGGCTAGGGTGCGCTGGCTCTTGCTCCTGCGCGCGCCACCGCATAGATAGGCGGAAACCGAATTAACAGC
GCGCGATACAAGGGACGATC

Downstream 100 bases:

>100_bases
TCCGCCATGGCACTCACACCTGATTTCGATGCGTTTGAGCAGGCCTACAGCACAGGGCTGAACCAGATCGTATACACCAG
ACTGGCGGCCGACCTCGACA

Product: peptidyl-prolyl cis-trans isomerse D, putative

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MIKGFSLSKTAIWILMGLLILGLAGFGATNMSGNIRTIGTAGDKPIPVDDYFRQLQQEIRAVEQQTREVLPFQQAQQMGL
DRAVLQRLVATRSLDHETSQLGLSIGDEELRRRILDISAFQGINGEFDREGYRFALEQTGLSEAEFETQLREEVARTIVQ
GAVLGGIAMPETYVDTLVNYIGEQRSFTWSLLDASDLATPLGAPDDAVLRAHYDDNIDVFTLPETKQITYAWLTPDMLLD
SVEVDEEALREAYAQQSAEFNQPERRLVERLAFLDRQSAQQAADALAAGDSFDDLVRGRGLALEDIDLGDVSEAELGEAG
AGVFAADVGAVVGPFPSTLGPALFRVNAVLAAQETPFEDAIDLLRPQLAADRASRLVAAQAESFDDLLAAGATLEDLASE
TDMVVAQIDWTAQSTEEIAAYPTFRQAAAAVGPRDFPEIASLDDGGLFALRLDTVLPPRPAPFDEIREEIIAHWEAAETA
KRLAEQVAAQVGLLENGSSFADLGLDAIVEENLIRSDFVPRTPPGFLEDVFAMEVGKAQVIESDAAVILVRLDAVAPPAA
DGDAAALRTQLEQQASQQLARDIFEVFANDVVLRADPQINQQALQAVHVNFP

Sequences:

>Translated_612_residues
MIKGFSLSKTAIWILMGLLILGLAGFGATNMSGNIRTIGTAGDKPIPVDDYFRQLQQEIRAVEQQTREVLPFQQAQQMGL
DRAVLQRLVATRSLDHETSQLGLSIGDEELRRRILDISAFQGINGEFDREGYRFALEQTGLSEAEFETQLREEVARTIVQ
GAVLGGIAMPETYVDTLVNYIGEQRSFTWSLLDASDLATPLGAPDDAVLRAHYDDNIDVFTLPETKQITYAWLTPDMLLD
SVEVDEEALREAYAQQSAEFNQPERRLVERLAFLDRQSAQQAADALAAGDSFDDLVRGRGLALEDIDLGDVSEAELGEAG
AGVFAADVGAVVGPFPSTLGPALFRVNAVLAAQETPFEDAIDLLRPQLAADRASRLVAAQAESFDDLLAAGATLEDLASE
TDMVVAQIDWTAQSTEEIAAYPTFRQAAAAVGPRDFPEIASLDDGGLFALRLDTVLPPRPAPFDEIREEIIAHWEAAETA
KRLAEQVAAQVGLLENGSSFADLGLDAIVEENLIRSDFVPRTPPGFLEDVFAMEVGKAQVIESDAAVILVRLDAVAPPAA
DGDAAALRTQLEQQASQQLARDIFEVFANDVVLRADPQINQQALQAVHVNFP
>Mature_612_residues
MIKGFSLSKTAIWILMGLLILGLAGFGATNMSGNIRTIGTAGDKPIPVDDYFRQLQQEIRAVEQQTREVLPFQQAQQMGL
DRAVLQRLVATRSLDHETSQLGLSIGDEELRRRILDISAFQGINGEFDREGYRFALEQTGLSEAEFETQLREEVARTIVQ
GAVLGGIAMPETYVDTLVNYIGEQRSFTWSLLDASDLATPLGAPDDAVLRAHYDDNIDVFTLPETKQITYAWLTPDMLLD
SVEVDEEALREAYAQQSAEFNQPERRLVERLAFLDRQSAQQAADALAAGDSFDDLVRGRGLALEDIDLGDVSEAELGEAG
AGVFAADVGAVVGPFPSTLGPALFRVNAVLAAQETPFEDAIDLLRPQLAADRASRLVAAQAESFDDLLAAGATLEDLASE
TDMVVAQIDWTAQSTEEIAAYPTFRQAAAAVGPRDFPEIASLDDGGLFALRLDTVLPPRPAPFDEIREEIIAHWEAAETA
KRLAEQVAAQVGLLENGSSFADLGLDAIVEENLIRSDFVPRTPPGFLEDVFAMEVGKAQVIESDAAVILVRLDAVAPPAA
DGDAAALRTQLEQQASQQLARDIFEVFANDVVLRADPQINQQALQAVHVNFP

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=500, Percent_Identity=21.8, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 66418; Mature: 66418

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGFSLSKTAIWILMGLLILGLAGFGATNMSGNIRTIGTAGDKPIPVDDYFRQLQQEIR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AVEQQTREVLPFQQAQQMGLDRAVLQRLVATRSLDHETSQLGLSIGDEELRRRILDISAF
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
QGINGEFDREGYRFALEQTGLSEAEFETQLREEVARTIVQGAVLGGIAMPETYVDTLVNY
CCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IGEQRSFTWSLLDASDLATPLGAPDDAVLRAHYDDNIDVFTLPETKQITYAWLTPDMLLD
HCCCCCCEEEEECHHHHCCCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEECHHHHHH
SVEVDEEALREAYAQQSAEFNQPERRLVERLAFLDRQSAQQAADALAAGDSFDDLVRGRG
HCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
LALEDIDLGDVSEAELGEAGAGVFAADVGAVVGPFPSTLGPALFRVNAVLAAQETPFEDA
CEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHH
IDLLRPQLAADRASRLVAAQAESFDDLLAAGATLEDLASETDMVVAQIDWTAQSTEEIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCCCHHHHHH
YPTFRQAAAAVGPRDFPEIASLDDGGLFALRLDTVLPPRPAPFDEIREEIIAHWEAAETA
CCCHHHHHHHCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRLAEQVAAQVGLLENGSSFADLGLDAIVEENLIRSDFVPRTPPGFLEDVFAMEVGKAQV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHH
IESDAAVILVRLDAVAPPAADGDAAALRTQLEQQASQQLARDIFEVFANDVVLRADPQIN
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
QQALQAVHVNFP
HHHHHHHCCCCC
>Mature Secondary Structure
MIKGFSLSKTAIWILMGLLILGLAGFGATNMSGNIRTIGTAGDKPIPVDDYFRQLQQEIR
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
AVEQQTREVLPFQQAQQMGLDRAVLQRLVATRSLDHETSQLGLSIGDEELRRRILDISAF
HHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHH
QGINGEFDREGYRFALEQTGLSEAEFETQLREEVARTIVQGAVLGGIAMPETYVDTLVNY
CCCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IGEQRSFTWSLLDASDLATPLGAPDDAVLRAHYDDNIDVFTLPETKQITYAWLTPDMLLD
HCCCCCCEEEEECHHHHCCCCCCCCCCEEEEECCCCCEEEECCCCCCEEEEEECHHHHHH
SVEVDEEALREAYAQQSAEFNQPERRLVERLAFLDRQSAQQAADALAAGDSFDDLVRGRG
HCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
LALEDIDLGDVSEAELGEAGAGVFAADVGAVVGPFPSTLGPALFRVNAVLAAQETPFEDA
CEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHH
IDLLRPQLAADRASRLVAAQAESFDDLLAAGATLEDLASETDMVVAQIDWTAQSTEEIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCCCHHHHHH
YPTFRQAAAAVGPRDFPEIASLDDGGLFALRLDTVLPPRPAPFDEIREEIIAHWEAAETA
CCCHHHHHHHCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KRLAEQVAAQVGLLENGSSFADLGLDAIVEENLIRSDFVPRTPPGFLEDVFAMEVGKAQV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHH
IESDAAVILVRLDAVAPPAADGDAAALRTQLEQQASQQLARDIFEVFANDVVLRADPQIN
CCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
QQALQAVHVNFP
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]