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The map label for this gene is rutR [H]

Identifier: 110680291

GI number: 110680291

Start: 2979322

End: 2979930

Strand: Direct

Name: rutR [H]

Synonym: RD1_3102

Alternate gene names: 110680291

Gene position: 2979322-2979930 (Clockwise)

Preceding gene: 110680281

Following gene: 110680296

Centisome position: 72.08

GC content: 57.96

Gene sequence:

>609_bases
ATGACAAAGACTGAAACCCGCATACAGAAAAAGAACCAGGCGGCCATTCTCAGCGCCGGGTTGCAGGTCTTTTCGCAATT
TGGATTTCGCGGCTCCACTCTGGATCAGATCGCTGCCGAGGCGGGACTGTCAAAGCCGAACATCCTGTATTACTTCGCCT
CCAAGGATGCGATCTATCGCGCCCTTTTGACCCAGTTGCTGGATGAGTGGCTACAGCCCATCTATGAGATTGATGCCAGT
GGCGACCCGGTCGAAGAGCTGCTTTCCTATGCGCGGCGCAAACTAGAGATGAGCCGGGATTATCCCCGCGAAAGCCGCCT
TTTTGCCAATGAGGTGATACAGGGTGCGCCGCGTATCGGCGACGCCCTCAGCGGTGAGTTGCGCCGGGTCGTGAACAAGA
TCGCCGCGATCATCGACGGCTGGATCCGCGAGGGTCGCATTCAGCCGGTGGACCCGCATCACCTGATCTTTTCCATCTGG
TCCGTGACCCAGCACTACGCAGATTTTGACGTTCAGGTGCGCGCCATCCTGCTGGATCAGGACCCTTTTCCCGGCGCCGA
GCAACACCTCGAAGACATGCTGCGGCGGATGCTGACCCCTCAAACCTAA

Upstream 100 bases:

>100_bases
GAGTCAAGACGTATGCTTGACATATCAAGGGGATCATCGTGCTGTCGCACAACCGGCAGGCACCACAATCAAAGATATTC
CACCAATACGGGCGCGGCAG

Downstream 100 bases:

>100_bases
CTGCCGAAGCACTCAGGATGAGTACTCCGGCAGCCGGGGAGAAACGGTTGTCGTGGATTACTCGGCGGCAACCGCGCCGG
GGTTGTTGGGGTGCGTGGTC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Rut operon repressor [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTKTETRIQKKNQAAILSAGLQVFSQFGFRGSTLDQIAAEAGLSKPNILYYFASKDAIYRALLTQLLDEWLQPIYEIDAS
GDPVEELLSYARRKLEMSRDYPRESRLFANEVIQGAPRIGDALSGELRRVVNKIAAIIDGWIREGRIQPVDPHHLIFSIW
SVTQHYADFDVQVRAILLDQDPFPGAEQHLEDMLRRMLTPQT

Sequences:

>Translated_202_residues
MTKTETRIQKKNQAAILSAGLQVFSQFGFRGSTLDQIAAEAGLSKPNILYYFASKDAIYRALLTQLLDEWLQPIYEIDAS
GDPVEELLSYARRKLEMSRDYPRESRLFANEVIQGAPRIGDALSGELRRVVNKIAAIIDGWIREGRIQPVDPHHLIFSIW
SVTQHYADFDVQVRAILLDQDPFPGAEQHLEDMLRRMLTPQT
>Mature_201_residues
TKTETRIQKKNQAAILSAGLQVFSQFGFRGSTLDQIAAEAGLSKPNILYYFASKDAIYRALLTQLLDEWLQPIYEIDASG
DPVEELLSYARRKLEMSRDYPRESRLFANEVIQGAPRIGDALSGELRRVVNKIAAIIDGWIREGRIQPVDPHHLIFSIWS
VTQHYADFDVQVRAILLDQDPFPGAEQHLEDMLRRMLTPQT

Specific function: Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787249, Length=175, Percent_Identity=49.7142857142857, Blast_Score=186, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR019915
- InterPro:   IPR001647
- InterPro:   IPR013573 [H]

Pfam domain/function: PF08362 TetR_C_3; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23015; Mature: 22883

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTETRIQKKNQAAILSAGLQVFSQFGFRGSTLDQIAAEAGLSKPNILYYFASKDAIYR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHH
ALLTQLLDEWLQPIYEIDASGDPVEELLSYARRKLEMSRDYPRESRLFANEVIQGAPRIG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
DALSGELRRVVNKIAAIIDGWIREGRIQPVDPHHLIFSIWSVTQHYADFDVQVRAILLDQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
DPFPGAEQHLEDMLRRMLTPQT
CCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKTETRIQKKNQAAILSAGLQVFSQFGFRGSTLDQIAAEAGLSKPNILYYFASKDAIYR
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHH
ALLTQLLDEWLQPIYEIDASGDPVEELLSYARRKLEMSRDYPRESRLFANEVIQGAPRIG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
DALSGELRRVVNKIAAIIDGWIREGRIQPVDPHHLIFSIWSVTQHYADFDVQVRAILLDQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECC
DPFPGAEQHLEDMLRRMLTPQT
CCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]