Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 110680183

GI number: 110680183

Start: 2860544

End: 2861542

Strand: Direct

Name: gap [H]

Synonym: RD1_2984

Alternate gene names: 110680183

Gene position: 2860544-2861542 (Clockwise)

Preceding gene: 110680181

Following gene: 110680188

Centisome position: 69.21

GC content: 60.66

Gene sequence:

>999_bases
ATGACGATCAAAGTAGGTATCAATGGGTTTGGCCGTATCGGTCGCTGTACGCTGGCCCACATTGTAAGCTCCGGGCGCAA
CGACATCGACGTGGTCGCCGTCAACGCCACCGGGCCGCTGGCCACAGCGGCGCATCTTCTGAAATACGACAGCGTGCATG
GCCGTTTTCCGGGCGAGATCGTGACCGGGGCCAATACGATGGACCTGGGGCGCGGGCCCATTCGCATGATGTCCAGCTAC
GATATGAACGATCTGAACTGGGAAGGTGTTGACGTGGTGTTGGAATGCACCGGGCAGCACAATGATGGCAACAAGGCCAA
AACACATATCGAACGGGGTGCCGAACGGGTTCTGATTTCCGCCCCGGCCAAGAATGTTGACCGCACGGTCGTCTTTGGCG
TGAACCACCGCGACATGATCTCAAAGGATGCGGTCGTCTCGAACGGGTCCTGCACAACGAACTGTCTTGCCCCGCTGGCG
AAGGTGCTTGATGAAGCCTTTGGCATTGAACGCGGCGTGATGACCACCATCCACTCCTATACCGGGGATCAACCGACGCT
GGATCGACGCCACAATGATCTATACCGCGCACGTGCGGCGGCCATGTCCATCATCCCGACCTCAACCGGTGCCGCGAAGG
CGCTCGGAGAAGTCCTGCCCAACCTCGCCGGCAAGCTGGATGGCACCGCCCTGCGCGTGCCGACCCCAAACGTGTCCGCC
GTTGATCTGACATTCGAAGCGGGGCGCGACGTCACGGTCGAAGACGTCAACGCCGCATTGCAGGAAGCCGCCTTGGGCCA
TATGTCCCGCGTGCTTGCCTATGATGATGAGGCCAAAGTGTCGGTGGACTTCAACCACACGGAGCACAGCTGCATCTTCG
CACCGGATCAGACCAAGGTGGTGGGCGGGCGCACCGTGCGTGTCCTGGCGTGGTATGACAACGAATGGGCGTTCTCTGCG
CGGATGGCTGATGTCGCGGTCGCGATGGGTCGCCTGTAA

Upstream 100 bases:

>100_bases
TAACGCTAACACACGGAAAACACGTCGATTTAGTCATTCCCCGAAGGCCACAGGGGCGTTATACAGCCCCCAGATGAGGC
GTGATGTGGAGACAGGTGAA

Downstream 100 bases:

>100_bases
CGCGCAACGGCCCTGCACCCAGCACAGTTTCGGCGGACTGCCGTGCCTCCTCAGGCGCGGCAGTTTTTCGTTGAATGACG
AGAACTCTGCGCATGCTACG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTIKVGINGFGRIGRCTLAHIVSSGRNDIDVVAVNATGPLATAAHLLKYDSVHGRFPGEIVTGANTMDLGRGPIRMMSSY
DMNDLNWEGVDVVLECTGQHNDGNKAKTHIERGAERVLISAPAKNVDRTVVFGVNHRDMISKDAVVSNGSCTTNCLAPLA
KVLDEAFGIERGVMTTIHSYTGDQPTLDRRHNDLYRARAAAMSIIPTSTGAAKALGEVLPNLAGKLDGTALRVPTPNVSA
VDLTFEAGRDVTVEDVNAALQEAALGHMSRVLAYDDEAKVSVDFNHTEHSCIFAPDQTKVVGGRTVRVLAWYDNEWAFSA
RMADVAVAMGRL

Sequences:

>Translated_332_residues
MTIKVGINGFGRIGRCTLAHIVSSGRNDIDVVAVNATGPLATAAHLLKYDSVHGRFPGEIVTGANTMDLGRGPIRMMSSY
DMNDLNWEGVDVVLECTGQHNDGNKAKTHIERGAERVLISAPAKNVDRTVVFGVNHRDMISKDAVVSNGSCTTNCLAPLA
KVLDEAFGIERGVMTTIHSYTGDQPTLDRRHNDLYRARAAAMSIIPTSTGAAKALGEVLPNLAGKLDGTALRVPTPNVSA
VDLTFEAGRDVTVEDVNAALQEAALGHMSRVLAYDDEAKVSVDFNHTEHSCIFAPDQTKVVGGRTVRVLAWYDNEWAFSA
RMADVAVAMGRL
>Mature_331_residues
TIKVGINGFGRIGRCTLAHIVSSGRNDIDVVAVNATGPLATAAHLLKYDSVHGRFPGEIVTGANTMDLGRGPIRMMSSYD
MNDLNWEGVDVVLECTGQHNDGNKAKTHIERGAERVLISAPAKNVDRTVVFGVNHRDMISKDAVVSNGSCTTNCLAPLAK
VLDEAFGIERGVMTTIHSYTGDQPTLDRRHNDLYRARAAAMSIIPTSTGAAKALGEVLPNLAGKLDGTALRVPTPNVSAV
DLTFEAGRDVTVEDVNAALQEAALGHMSRVLAYDDEAKVSVDFNHTEHSCIFAPDQTKVVGGRTVRVLAWYDNEWAFSAR
MADVAVAMGRL

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=40.4833836858006, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=41.8181818181818, Blast_Score=231, Evalue=8e-61,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=44.311377245509, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=44.5121951219512, Blast_Score=260, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=43.5435435435435, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=43.2432432432432, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=42.042042042042, Blast_Score=243, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=42.042042042042, Blast_Score=243, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=44.0729483282675, Blast_Score=257, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=42.5531914893617, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=41.3373860182371, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=43.6746987951807, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=43.6746987951807, Blast_Score=254, Evalue=5e-68,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=43.8438438438438, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=43.8438438438438, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=38.719512195122, Blast_Score=235, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35583; Mature: 35452

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRCTLAHIVSSGRNDIDVVAVNATGPLATAAHLLKYDSVHGRFPGEI
CEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCE
VTGANTMDLGRGPIRMMSSYDMNDLNWEGVDVVLECTGQHNDGNKAKTHIERGAERVLIS
EECCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEE
APAKNVDRTVVFGVNHRDMISKDAVVSNGSCTTNCLAPLAKVLDEAFGIERGVMTTIHSY
CCCCCCCCEEEEECCCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHC
TGDQPTLDRRHNDLYRARAAAMSIIPTSTGAAKALGEVLPNLAGKLDGTALRVPTPNVSA
CCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEE
VDLTFEAGRDVTVEDVNAALQEAALGHMSRVLAYDDEAKVSVDFNHTEHSCIFAPDQTKV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCCCCEE
VGGRTVRVLAWYDNEWAFSARMADVAVAMGRL
ECCCEEEEEEEECCCEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIKVGINGFGRIGRCTLAHIVSSGRNDIDVVAVNATGPLATAAHLLKYDSVHGRFPGEI
EEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCE
VTGANTMDLGRGPIRMMSSYDMNDLNWEGVDVVLECTGQHNDGNKAKTHIERGAERVLIS
EECCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEE
APAKNVDRTVVFGVNHRDMISKDAVVSNGSCTTNCLAPLAKVLDEAFGIERGVMTTIHSY
CCCCCCCCEEEEECCCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHC
TGDQPTLDRRHNDLYRARAAAMSIIPTSTGAAKALGEVLPNLAGKLDGTALRVPTPNVSA
CCCCCCHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCEE
VDLTFEAGRDVTVEDVNAALQEAALGHMSRVLAYDDEAKVSVDFNHTEHSCIFAPDQTKV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEECCCCCEE
VGGRTVRVLAWYDNEWAFSARMADVAVAMGRL
ECCCEEEEEEEECCCEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]