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The map label for this gene is rimK [H]

Identifier: 110680156

GI number: 110680156

Start: 2835732

End: 2837111

Strand: Direct

Name: rimK [H]

Synonym: RD1_2956

Alternate gene names: 110680156

Gene position: 2835732-2837111 (Clockwise)

Preceding gene: 110680155

Following gene: 110680157

Centisome position: 68.61

GC content: 59.93

Gene sequence:

>1380_bases
ATGGAAAAGCTCACGTTCGGATGGGAGGAATGGGTATCTCTGCCCGACCTCGGCTTGCCCGCAATCAAGGCCAAGGTGGA
CACAGGCGCGCGCACCTCGGCGCTGCATGCCCATGACATCGAAGTCTTCGGCCCAGCCAAAACGCCAAAAGTGCGCTTCA
ACGTGCATCCGGTGTCGGGTCGTGATGATATTTCCATCACCTGCTCGGCGCCACTTGTGGACCGCAGGGAGGTTACCTCC
TCAAATGGCGAGGCCGAACAGCGGTTCGTGATCTCTTCGGAATTGCATGTTGGCGGACAGAACTGGCCAATCGAGATTAC
GCTCACAAACCGCGCCTCGATGAATTCGCGCATGCTGCTGGGGCGACAGGCGCTCAGCGATCACATCTCGATCTCGCCGA
CGGAACGTCATCTGCAACCCGAACTCAGTTATGAGGACTATCACAGCGCATCGCTGAAAAAGGGCGCACCCAAACGCGCG
CTGCGCATCGCGGTTCTCAGCCGGGAGGATAACTACTCCACGCGGCGCCTTGTCGAGGTGGGAGAAGCCCGCGGTCACGT
GGTTGAAGTCATCGACACAACCCGTTGTTATATGGCGATTAATACCATGGCGCCAGAAGTGCATTATGACGGGAAACGCC
TGCCGCGCTATGATGCGGTCATTCCCCGCATCGGGGCTTCGATCACGCCCTATGGCACCGCGGTGATCCGCCAGTTCGAA
GCAATTGGGACCTATTGCGTGAACGGTTCCGCCGGGATCACCGCCAGCCGGGACAAACTGCACGCCCATCAGGTGCTGGC
CACAAAACGGATCGGCATGCCATCGACGGCCTTTGCCGCCTCACCCAAGGACACATCGAACCTGATGGCATTGGTCGGCA
CCGCACCGCTGATTGTCAAATTGCTCGAAAGCACGCAAGGCAAAGGCGTGGTTCTGGCCGAGACAAAAAAAGCAGCCGAG
TCCGTCATAGATGCATTCCGGGGTCTCAAGGCCAATTTTCTGGTGCAGGATTTCGTCAAGGAAGCAGCCGGAGAGGACAT
CCGCTGCCTTGTGATCGCCGGCAAGGTCGTTGCGGCCATGAAGCGCACCGGGGCGGAGGGGGATTTTCGTTCCAACCTGC
ATCGGGGCGGATCGGCGAAAGTCGTGCGCATCACCAAGCAGGAGCGCGACACCGCCGTGCGCGCCGCCCGTGCCTTTGGA
CTCGGCAAGGCCGGTGTGGATTTGCTGCGCGCCACCGCAGGCCCCAAGGTGCTTGAGGTCAACTCCTCCCCCGGTTTTGA
GGGCATCGAAAAAGCGACTGGCAAAGATATTGTGGGCAAGCTCTATGATGAGATCGAAACCCGCGTGCGCCCGCAGCCTG
CGCGCAAGCGGAGATCCTGA

Upstream 100 bases:

>100_bases
CCAGGGATATCAACGACAATTAATCTCAGCGCCTTTCGGTTGAGGTCAGGGCAACCACCTGCTACCCAAAGGGTCATTTT
TGCGGTTTGGGGGACTGGCG

Downstream 100 bases:

>100_bases
ACTGGCACAAAGGCCGGCGCGCAGCCTCTTTACGGCTCCACCGACAATCCCTATATAAATGATCAGGAACAAAATCGAGG
CCTGAGATGAACAACGTACC

Product: ribosomal protein S6 modification protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEKLTFGWEEWVSLPDLGLPAIKAKVDTGARTSALHAHDIEVFGPAKTPKVRFNVHPVSGRDDISITCSAPLVDRREVTS
SNGEAEQRFVISSELHVGGQNWPIEITLTNRASMNSRMLLGRQALSDHISISPTERHLQPELSYEDYHSASLKKGAPKRA
LRIAVLSREDNYSTRRLVEVGEARGHVVEVIDTTRCYMAINTMAPEVHYDGKRLPRYDAVIPRIGASITPYGTAVIRQFE
AIGTYCVNGSAGITASRDKLHAHQVLATKRIGMPSTAFAASPKDTSNLMALVGTAPLIVKLLESTQGKGVVLAETKKAAE
SVIDAFRGLKANFLVQDFVKEAAGEDIRCLVIAGKVVAAMKRTGAEGDFRSNLHRGGSAKVVRITKQERDTAVRAARAFG
LGKAGVDLLRATAGPKVLEVNSSPGFEGIEKATGKDIVGKLYDEIETRVRPQPARKRRS

Sequences:

>Translated_459_residues
MEKLTFGWEEWVSLPDLGLPAIKAKVDTGARTSALHAHDIEVFGPAKTPKVRFNVHPVSGRDDISITCSAPLVDRREVTS
SNGEAEQRFVISSELHVGGQNWPIEITLTNRASMNSRMLLGRQALSDHISISPTERHLQPELSYEDYHSASLKKGAPKRA
LRIAVLSREDNYSTRRLVEVGEARGHVVEVIDTTRCYMAINTMAPEVHYDGKRLPRYDAVIPRIGASITPYGTAVIRQFE
AIGTYCVNGSAGITASRDKLHAHQVLATKRIGMPSTAFAASPKDTSNLMALVGTAPLIVKLLESTQGKGVVLAETKKAAE
SVIDAFRGLKANFLVQDFVKEAAGEDIRCLVIAGKVVAAMKRTGAEGDFRSNLHRGGSAKVVRITKQERDTAVRAARAFG
LGKAGVDLLRATAGPKVLEVNSSPGFEGIEKATGKDIVGKLYDEIETRVRPQPARKRRS
>Mature_459_residues
MEKLTFGWEEWVSLPDLGLPAIKAKVDTGARTSALHAHDIEVFGPAKTPKVRFNVHPVSGRDDISITCSAPLVDRREVTS
SNGEAEQRFVISSELHVGGQNWPIEITLTNRASMNSRMLLGRQALSDHISISPTERHLQPELSYEDYHSASLKKGAPKRA
LRIAVLSREDNYSTRRLVEVGEARGHVVEVIDTTRCYMAINTMAPEVHYDGKRLPRYDAVIPRIGASITPYGTAVIRQFE
AIGTYCVNGSAGITASRDKLHAHQVLATKRIGMPSTAFAASPKDTSNLMALVGTAPLIVKLLESTQGKGVVLAETKKAAE
SVIDAFRGLKANFLVQDFVKEAAGEDIRCLVIAGKVVAAMKRTGAEGDFRSNLHRGGSAKVVRITKQERDTAVRAARAFG
LGKAGVDLLRATAGPKVLEVNSSPGFEGIEKATGKDIVGKLYDEIETRVRPQPARKRRS

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI164663810, Length=212, Percent_Identity=30.188679245283, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI134254462, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1787076, Length=287, Percent_Identity=59.2334494773519, Blast_Score=343, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008503
- InterPro:   IPR009007
- InterPro:   IPR004666 [H]

Pfam domain/function: PF05618 DUF785; PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 49876; Mature: 49876

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLTFGWEEWVSLPDLGLPAIKAKVDTGARTSALHAHDIEVFGPAKTPKVRFNVHPVSG
CCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCEEEECCEEEECCCCCCEEEEEEEECCC
RDDISITCSAPLVDRREVTSSNGEAEQRFVISSELHVGGQNWPIEITLTNRASMNSRMLL
CCCEEEEECCCCCCCHHHCCCCCCCHHEEEEEEEEEECCCCCCEEEEECCCCCCCCHHHH
GRQALSDHISISPTERHLQPELSYEDYHSASLKKGAPKRALRIAVLSREDNYSTRRLVEV
HHHHHHCCCCCCCHHHHCCCCCCCCHHHCCHHCCCCCCCEEEEEEEECCCCCCHHHHHHH
GEARGHVVEVIDTTRCYMAINTMAPEVHYDGKRLPRYDAVIPRIGASITPYGTAVIRQFE
HCCCCCEEEEEECCEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
AIGTYCVNGSAGITASRDKLHAHQVLATKRIGMPSTAFAASPKDTSNLMALVGTAPLIVK
HHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLESTQGKGVVLAETKKAAESVIDAFRGLKANFLVQDFVKEAAGEDIRCLVIAGKVVAAM
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
KRTGAEGDFRSNLHRGGSAKVVRITKQERDTAVRAARAFGLGKAGVDLLRATAGPKVLEV
HHCCCCCCHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEE
NSSPGFEGIEKATGKDIVGKLYDEIETRVRPQPARKRRS
CCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure
MEKLTFGWEEWVSLPDLGLPAIKAKVDTGARTSALHAHDIEVFGPAKTPKVRFNVHPVSG
CCCCCCCHHHHCCCCCCCCCCEEEECCCCCCCCEEEECCEEEECCCCCCEEEEEEEECCC
RDDISITCSAPLVDRREVTSSNGEAEQRFVISSELHVGGQNWPIEITLTNRASMNSRMLL
CCCEEEEECCCCCCCHHHCCCCCCCHHEEEEEEEEEECCCCCCEEEEECCCCCCCCHHHH
GRQALSDHISISPTERHLQPELSYEDYHSASLKKGAPKRALRIAVLSREDNYSTRRLVEV
HHHHHHCCCCCCCHHHHCCCCCCCCHHHCCHHCCCCCCCEEEEEEEECCCCCCHHHHHHH
GEARGHVVEVIDTTRCYMAINTMAPEVHYDGKRLPRYDAVIPRIGASITPYGTAVIRQFE
HCCCCCEEEEEECCEEEEEEECCCCCEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
AIGTYCVNGSAGITASRDKLHAHQVLATKRIGMPSTAFAASPKDTSNLMALVGTAPLIVK
HHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLESTQGKGVVLAETKKAAESVIDAFRGLKANFLVQDFVKEAAGEDIRCLVIAGKVVAAM
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
KRTGAEGDFRSNLHRGGSAKVVRITKQERDTAVRAARAFGLGKAGVDLLRATAGPKVLEV
HHCCCCCCHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEE
NSSPGFEGIEKATGKDIVGKLYDEIETRVRPQPARKRRS
CCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA