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The map label for this gene is tctD [H]

Identifier: 110680145

GI number: 110680145

Start: 2824025

End: 2824690

Strand: Reverse

Name: tctD [H]

Synonym: RD1_2945

Alternate gene names: 110680145

Gene position: 2824690-2824025 (Counterclockwise)

Preceding gene: 110680149

Following gene: 110680144

Centisome position: 68.34

GC content: 56.46

Gene sequence:

>666_bases
ATGAAATTTCTTTTGGTGGAAGACAACATTGAATTGGCGCAGGCGGTGTTGGCGCGTTTGCGTCTGGATGGCCATGTGAT
TGATCATGCTGAGAAAATTGAAGACGCCATGGCCTATGCGCAGGTGGGCGATTATGATCTGATCCTGCTTGACATCATGT
TGCCGGATGGGGATGGGCGCGACTTTCTGCAACAGCATCGTCAAAGCCAGAAGGACACGCCGGTCATCGTTCTGACGGCG
CGCTCGCAGGTTTCAGACAGAATCACCCTGCTGGATCTGGGGGCGGATGACTATGTCACCAAACCGTTTGACCACGCGGA
ACTTGAGGCGCGCTGCCGTGCGGTGCTGCGCCGTCGGGCGGGGTCTGCGCAAACCGTCACGCAGCTGCGCGATGTGATCT
TTGATCCGGTCCGGGGCAGTCTGAGCGTCGCGGGCCAATCCGTTAAGCTGCGAAACCGGGAGCTGCGGCTGCTTGAGTTG
TTCATCAACGCCCCGGGGCAGCTTTTTTCGAAACAGAAGCTGGTGGATCGGCTGTTTTCCTACGACGAAGATGTCTCCGA
CAATGCGATCGAGGTGTATGTCGGTCGCCTTCGTAAACATCTTGAGCCGTCGCAATTGCGGATCAAAACCTCGCGCGGTT
TGGGGTATAGTCTGGAACATGTCTGA

Upstream 100 bases:

>100_bases
CCCATTTGACAACTGTAGCTGTTCCGGCTCAGTTGATTGCACTCAAACATGGCAACCTGACATGGACCTGTCACGCGGCC
GCTTCATGCGAAATGCAACG

Downstream 100 bases:

>100_bases
GGCGGTCCGCTCTTCGGCATCTCTGCGCCGCCGCCTGACGCTTGGCCTGATCGGCGGTGCGGCGGTGCTGGCGGTTCTGA
TTTACCTGTTCACGCGCGCC

Product: DNA-binding response regulator, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKFLLVEDNIELAQAVLARLRLDGHVIDHAEKIEDAMAYAQVGDYDLILLDIMLPDGDGRDFLQQHRQSQKDTPVIVLTA
RSQVSDRITLLDLGADDYVTKPFDHAELEARCRAVLRRRAGSAQTVTQLRDVIFDPVRGSLSVAGQSVKLRNRELRLLEL
FINAPGQLFSKQKLVDRLFSYDEDVSDNAIEVYVGRLRKHLEPSQLRIKTSRGLGYSLEHV

Sequences:

>Translated_221_residues
MKFLLVEDNIELAQAVLARLRLDGHVIDHAEKIEDAMAYAQVGDYDLILLDIMLPDGDGRDFLQQHRQSQKDTPVIVLTA
RSQVSDRITLLDLGADDYVTKPFDHAELEARCRAVLRRRAGSAQTVTQLRDVIFDPVRGSLSVAGQSVKLRNRELRLLEL
FINAPGQLFSKQKLVDRLFSYDEDVSDNAIEVYVGRLRKHLEPSQLRIKTSRGLGYSLEHV
>Mature_221_residues
MKFLLVEDNIELAQAVLARLRLDGHVIDHAEKIEDAMAYAQVGDYDLILLDIMLPDGDGRDFLQQHRQSQKDTPVIVLTA
RSQVSDRITLLDLGADDYVTKPFDHAELEARCRAVLRRRAGSAQTVTQLRDVIFDPVRGSLSVAGQSVKLRNRELRLLEL
FINAPGQLFSKQKLVDRLFSYDEDVSDNAIEVYVGRLRKHLEPSQLRIKTSRGLGYSLEHV

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=34.8623853211009, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=37.9464285714286, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=34.4036697247706, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=38.8392857142857, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=35, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=36.1990950226244, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786911, Length=218, Percent_Identity=34.8623853211009, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.8947368421053, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=31.3636363636364, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=35.8407079646018, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.5309734513274, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=28.1938325991189, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787229, Length=181, Percent_Identity=35.3591160220994, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI145693140, Length=188, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25049; Mature: 25049

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLLVEDNIELAQAVLARLRLDGHVIDHAEKIEDAMAYAQVGDYDLILLDIMLPDGDGR
CEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCH
DFLQQHRQSQKDTPVIVLTARSQVSDRITLLDLGADDYVTKPFDHAELEARCRAVLRRRA
HHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
GSAQTVTQLRDVIFDPVRGSLSVAGQSVKLRNRELRLLELFINAPGQLFSKQKLVDRLFS
CCHHHHHHHHHHHHCCCCCCHHHCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
YDEDVSDNAIEVYVGRLRKHLEPSQLRIKTSRGLGYSLEHV
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCC
>Mature Secondary Structure
MKFLLVEDNIELAQAVLARLRLDGHVIDHAEKIEDAMAYAQVGDYDLILLDIMLPDGDGR
CEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCH
DFLQQHRQSQKDTPVIVLTARSQVSDRITLLDLGADDYVTKPFDHAELEARCRAVLRRRA
HHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
GSAQTVTQLRDVIFDPVRGSLSVAGQSVKLRNRELRLLELFINAPGQLFSKQKLVDRLFS
CCHHHHHHHHHHHHCCCCCCHHHCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
YDEDVSDNAIEVYVGRLRKHLEPSQLRIKTSRGLGYSLEHV
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]