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The map label for this gene is srr [H]

Identifier: 110680094

GI number: 110680094

Start: 2769884

End: 2770855

Strand: Reverse

Name: srr [H]

Synonym: RD1_2891

Alternate gene names: 110680094

Gene position: 2770855-2769884 (Counterclockwise)

Preceding gene: 110680095

Following gene: 110680093

Centisome position: 67.04

GC content: 59.05

Gene sequence:

>972_bases
ATGCTGGATGCTATGACCGGGTCGGATCTGACACTTGAGGACGTGCGCACCGCGCATGACCGGATCAAACCCTATATCCA
CGAAACACCCATTCTGACGTCGTCGTATTTCAATGCGCTGACCGGGGCGGAGTTGTTTTTCAAATGCGAAAACTTCCAAA
AGGCCGGTGCCTTCAAGGTGCGGGGGGCGTCCAACGCCGTCTTTGGCCTCAGCGACGAGATGGCTGAAAAAGGTGTGGCG
ACGCATTCATCGGGCAACCACGCCTTGTCCTTGTCCTATGCGGCAGGGCGGCGCGGTATTCCGTGTCATGTGGTGATGCC
GCGTACCGCCCCCGAAGCGAAAAAGGCAGCCGTGCGGGGCTATGGCGGGATCATCACCGAATGCGAACCCTCAACCACCA
GCCGCGAAGCGGTTTTTGCCGAAGTGCAGGCGGCGACGGGCGCGAATTTTGTGCATCCCTATAACGATCCGCGCGTGATC
GCTGGGCAGGCGACCTGTTCGCTTGAAATGTTGTCGCAGGTTGAGAATATGGATGCGGTTATCGCGCCGATTGGCGGAGG
TGGCATGATTTCGGGCACCTGTCTGACCCTGTCAAACCGCGCGCCCGAGATCGAGATATACGCAGCGGAGCCGGATCAGG
CCGATGACGCGGCGCGTTCGTTCCGGGCCGGGCATATCATTGCCGATGACGCGCCTGTGACCGTCGCTGACGGGCTTAAG
GTGCCCCTGAAGGAGAACACGTGGCACTTTGTGTCCAGTTTTGTGACGGATGTGCTGACCGCGTCTGAGCAAGAGATTAT
CGACGCGATGAAGCTGACATGGGAACGGATGAAAATCGTGATTGAGCCAAGCTGTGCCGTGCCGATGGCCACAATCCTGC
GCAACCCGGAGGTTTTCCGGGGCAAGCGCGTGGGGGTGATCATCACCGGTGGCAATGTGGATTTGGATAAACTGCCCTGG
ACGCTGGGCTAA

Upstream 100 bases:

>100_bases
GATTACCCGATTGAATTGGGCAGTGGTGTGGCGGCGGCGCAAGAGCATTTCCGCTCCAAATCCGGTGCTGCCATCAAATC
TGCTGCATAGGGAGGGCGAG

Downstream 100 bases:

>100_bases
GGAGGATGCACCATGAACAAGCAAGTGAACTTTGAAGACTATGAAGTCGGCTATGATATCCCTGCCGCGATTGGTATGGA
TGAGGCCGATATCCAGACGC

Product: serine racemase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MLDAMTGSDLTLEDVRTAHDRIKPYIHETPILTSSYFNALTGAELFFKCENFQKAGAFKVRGASNAVFGLSDEMAEKGVA
THSSGNHALSLSYAAGRRGIPCHVVMPRTAPEAKKAAVRGYGGIITECEPSTTSREAVFAEVQAATGANFVHPYNDPRVI
AGQATCSLEMLSQVENMDAVIAPIGGGGMISGTCLTLSNRAPEIEIYAAEPDQADDAARSFRAGHIIADDAPVTVADGLK
VPLKENTWHFVSSFVTDVLTASEQEIIDAMKLTWERMKIVIEPSCAVPMATILRNPEVFRGKRVGVIITGGNVDLDKLPW
TLG

Sequences:

>Translated_323_residues
MLDAMTGSDLTLEDVRTAHDRIKPYIHETPILTSSYFNALTGAELFFKCENFQKAGAFKVRGASNAVFGLSDEMAEKGVA
THSSGNHALSLSYAAGRRGIPCHVVMPRTAPEAKKAAVRGYGGIITECEPSTTSREAVFAEVQAATGANFVHPYNDPRVI
AGQATCSLEMLSQVENMDAVIAPIGGGGMISGTCLTLSNRAPEIEIYAAEPDQADDAARSFRAGHIIADDAPVTVADGLK
VPLKENTWHFVSSFVTDVLTASEQEIIDAMKLTWERMKIVIEPSCAVPMATILRNPEVFRGKRVGVIITGGNVDLDKLPW
TLG
>Mature_323_residues
MLDAMTGSDLTLEDVRTAHDRIKPYIHETPILTSSYFNALTGAELFFKCENFQKAGAFKVRGASNAVFGLSDEMAEKGVA
THSSGNHALSLSYAAGRRGIPCHVVMPRTAPEAKKAAVRGYGGIITECEPSTTSREAVFAEVQAATGANFVHPYNDPRVI
AGQATCSLEMLSQVENMDAVIAPIGGGGMISGTCLTLSNRAPEIEIYAAEPDQADDAARSFRAGHIIADDAPVTVADGLK
VPLKENTWHFVSSFVTDVLTASEQEIIDAMKLTWERMKIVIEPSCAVPMATILRNPEVFRGKRVGVIITGGNVDLDKLPW
TLG

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=316, Percent_Identity=46.8354430379747, Blast_Score=286, Evalue=2e-77,
Organism=Escherichia coli, GI1789505, Length=317, Percent_Identity=33.4384858044164, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790207, Length=296, Percent_Identity=30.0675675675676, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17508781, Length=316, Percent_Identity=36.7088607594937, Blast_Score=200, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI71991565, Length=310, Percent_Identity=34.5161290322581, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17537387, Length=308, Percent_Identity=31.1688311688312, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322631, Length=308, Percent_Identity=42.8571428571429, Blast_Score=237, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320930, Length=305, Percent_Identity=30.1639344262295, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319788, Length=284, Percent_Identity=21.830985915493, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355833, Length=307, Percent_Identity=30.9446254071661, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 34612; Mature: 34612

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDAMTGSDLTLEDVRTAHDRIKPYIHETPILTSSYFNALTGAELFFKCENFQKAGAFKV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEE
RGASNAVFGLSDEMAEKGVATHSSGNHALSLSYAAGRRGIPCHVVMPRTAPEAKKAAVRG
ECCCCEEEECCHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHC
YGGIITECEPSTTSREAVFAEVQAATGANFVHPYNDPRVIAGQATCSLEMLSQVENMDAV
CCCEEEECCCCCCCCHHHEEEHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEE
IAPIGGGGMISGTCLTLSNRAPEIEIYAAEPDQADDAARSFRAGHIIADDAPVTVADGLK
EEECCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCEEEECCCC
VPLKENTWHFVSSFVTDVLTASEQEIIDAMKLTWERMKIVIEPSCAVPMATILRNPEVFR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHCCCHHHC
GKRVGVIITGGNVDLDKLPWTLG
CCEEEEEEECCCCCHHCCCCCCC
>Mature Secondary Structure
MLDAMTGSDLTLEDVRTAHDRIKPYIHETPILTSSYFNALTGAELFFKCENFQKAGAFKV
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEE
RGASNAVFGLSDEMAEKGVATHSSGNHALSLSYAAGRRGIPCHVVMPRTAPEAKKAAVRG
ECCCCEEEECCHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHC
YGGIITECEPSTTSREAVFAEVQAATGANFVHPYNDPRVIAGQATCSLEMLSQVENMDAV
CCCEEEECCCCCCCCHHHEEEHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEE
IAPIGGGGMISGTCLTLSNRAPEIEIYAAEPDQADDAARSFRAGHIIADDAPVTVADGLK
EEECCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCCEEEECCCC
VPLKENTWHFVSSFVTDVLTASEQEIIDAMKLTWERMKIVIEPSCAVPMATILRNPEVFR
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHCCCHHHC
GKRVGVIITGGNVDLDKLPWTLG
CCEEEEEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA