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The map label for this gene is typA [H]

Identifier: 110679925

GI number: 110679925

Start: 2575353

End: 2577170

Strand: Direct

Name: typA [H]

Synonym: RD1_2707

Alternate gene names: 110679925

Gene position: 2575353-2577170 (Clockwise)

Preceding gene: 110679924

Following gene: 110679932

Centisome position: 62.31

GC content: 60.84

Gene sequence:

>1818_bases
ATGGACCTGCGAAACATCGCAATTATTGCTCACGTTGATCACGGTAAAACCACGCTTGTGGATGAATTGCTCAAACAATC
GGGCACCTACCGGGAAAATCAGGCCACCACGGAACGGGCGATGGACAGCAATGATCTGGAGCGCGAACGCGGTATCACCA
TTCTGGCCAAAGCCACATCCGTCGAATGGAAGGGCACGCGTATCAACATCGTGGATACCCCCGGCCACGCGGATTTCGGT
GGTGAGGTTGAGCGCATCCTGTCCATGGTGGACGGTGTGGTGCTGCTGGTGGACGCGGCCGAAGGGCCGATGCCGCAGAC
GAAATTCGTCACCTCAAAGGCGCTTGCCCTCGGCCTGCGCCCGATTGTTGTGCTGAACAAGGTCGACAAGCCAGACGCCG
AACCCGACCGCGCGCTGGATGAGTGTTTCGATCTTTTTGCCAACCTTGGCGCGGATGATGACCAACTGGATTTCCCGGCC
ATGTATGCCTCGGGGCGCTCTGGCTGGGCGGATGTCGAGCTGGATGGTCCGCGCAAGGACCTTTCGGCGCTGTTTGATCT
GATCGTCGAACACGTCCCCGCCCCGGCGCAACTGGCGCAGCGCGACGCGCCGTTCCAGATGCTGGCCACAACACTGGGTG
CGGACCCGTTTATCGGGCGCATTCTGACGGGCCGGGTTGAGGCCGGGACCGTCAAAGCGGGCGAAACCGTCAAGGCGCTG
AGCCGGGATGGCACGCAGATCGAATCCTTTCGTGTGACCAAAGTGCTGGCGTTTCGCGGGCTGAACCAGCAACCGATTGA
TCTGGCTGAAGCGGGTGATATCGTGAGCCTTGCGGGCATGTCCAAGGCAACCGTCGCCGACAGTATCGTCGCCCCGCAAG
TTACCGAGGCCCTGCCATCGCAGCCCATCGACCCGCCGACCATCACCGTCACCTTCGGCATCAATGACAGCCCGCTTGCT
GGCCGCGATGGCAAGAAGGTCCAGTCGCGCGTCATCCGGGAGCGGCTGATGAAAGAGGCGGAAAGCAACGTGGCGATCAA
GATTTCCGACACACCCGGCGGCGAGGCCTTCGAAGTTGCAGGGCGCGGCGAACTCCAGATGGGTGTTCTGATTGAAAACA
TGCGCCGCGAGGGGTTTGAACTCTCCATCTCGCGCCCGCAGGTGCTGTTTCGCGACATCGACGGGGTGCGCCATGAACCC
ATCGAAGAAGCCACGATCGATGTGGATGATGAATATTCCGGGGCCGTGATCGAAAAAATAACAGGCACGCGCCGGGGGGA
GCTTGTCGAGATGAAACCAGCCGGTGCGGGCAAGACGCGCATCGTGGCACATGTGCCCTCGCGCGGGTTGATCGGCTATC
ACGGCGAATTCCTGACCGATACGCGCGGCACGGGCGTGCTGAACCGCGTCTTTCATGGCTGGGCACCTCACAAGGGGCCT
ATTCCGGGCCGGCGGGCGGGTGTCCTGATTTCGATGGAAAACGGCACCTCGGTGGCCTATGCGCTGTGGAACCTTGAAGA
GCGCGGTAAAATGATGATCGGGGCGCAGGCTGATGTCTACACCGGTATGATCATCGGTGAGCACAGCCGTGAGAATGACC
TCGAAGTGAACCCGCTGAAAGGCAAGAAACTGACCAACGTGCGCGCCTCCGGTACGGATGAGGCCGTGCGGCTGACCACA
CCGATCACCCTCAGCCTGGAAGAAGCCATCGCCTATATCGACGATGATGAACTGGTCGAGGTGACACCAAACGCCATCCG
GTTGCGCAAACGCTACCTTGATCCGCATGAGCGCAAACGCATGGCGCGCGCAGGCTGA

Upstream 100 bases:

>100_bases
CCTTGGGCGATTATCGCTGGCTTTCTGGCAGGCTGCGCGGTATGCGGCCCCCAAAGCGGCGCCGGGAGGCGCGCATATTC
AGTCAAATCGAGGCGCTCTC

Downstream 100 bases:

>100_bases
ATGACTTTTCTGCGCCCGGTGCCGTGCCGGGCGCAAAGGGCGCTATTCGGTTGTCTCGATGATCATCAGATCCCGCTCGG
ACGCATCGCGCGCATGGTTT

Product: GTP-binding protein TypA, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MDLRNIAIIAHVDHGKTTLVDELLKQSGTYRENQATTERAMDSNDLERERGITILAKATSVEWKGTRINIVDTPGHADFG
GEVERILSMVDGVVLLVDAAEGPMPQTKFVTSKALALGLRPIVVLNKVDKPDAEPDRALDECFDLFANLGADDDQLDFPA
MYASGRSGWADVELDGPRKDLSALFDLIVEHVPAPAQLAQRDAPFQMLATTLGADPFIGRILTGRVEAGTVKAGETVKAL
SRDGTQIESFRVTKVLAFRGLNQQPIDLAEAGDIVSLAGMSKATVADSIVAPQVTEALPSQPIDPPTITVTFGINDSPLA
GRDGKKVQSRVIRERLMKEAESNVAIKISDTPGGEAFEVAGRGELQMGVLIENMRREGFELSISRPQVLFRDIDGVRHEP
IEEATIDVDDEYSGAVIEKITGTRRGELVEMKPAGAGKTRIVAHVPSRGLIGYHGEFLTDTRGTGVLNRVFHGWAPHKGP
IPGRRAGVLISMENGTSVAYALWNLEERGKMMIGAQADVYTGMIIGEHSRENDLEVNPLKGKKLTNVRASGTDEAVRLTT
PITLSLEEAIAYIDDDELVEVTPNAIRLRKRYLDPHERKRMARAG

Sequences:

>Translated_605_residues
MDLRNIAIIAHVDHGKTTLVDELLKQSGTYRENQATTERAMDSNDLERERGITILAKATSVEWKGTRINIVDTPGHADFG
GEVERILSMVDGVVLLVDAAEGPMPQTKFVTSKALALGLRPIVVLNKVDKPDAEPDRALDECFDLFANLGADDDQLDFPA
MYASGRSGWADVELDGPRKDLSALFDLIVEHVPAPAQLAQRDAPFQMLATTLGADPFIGRILTGRVEAGTVKAGETVKAL
SRDGTQIESFRVTKVLAFRGLNQQPIDLAEAGDIVSLAGMSKATVADSIVAPQVTEALPSQPIDPPTITVTFGINDSPLA
GRDGKKVQSRVIRERLMKEAESNVAIKISDTPGGEAFEVAGRGELQMGVLIENMRREGFELSISRPQVLFRDIDGVRHEP
IEEATIDVDDEYSGAVIEKITGTRRGELVEMKPAGAGKTRIVAHVPSRGLIGYHGEFLTDTRGTGVLNRVFHGWAPHKGP
IPGRRAGVLISMENGTSVAYALWNLEERGKMMIGAQADVYTGMIIGEHSRENDLEVNPLKGKKLTNVRASGTDEAVRLTT
PITLSLEEAIAYIDDDELVEVTPNAIRLRKRYLDPHERKRMARAG
>Mature_605_residues
MDLRNIAIIAHVDHGKTTLVDELLKQSGTYRENQATTERAMDSNDLERERGITILAKATSVEWKGTRINIVDTPGHADFG
GEVERILSMVDGVVLLVDAAEGPMPQTKFVTSKALALGLRPIVVLNKVDKPDAEPDRALDECFDLFANLGADDDQLDFPA
MYASGRSGWADVELDGPRKDLSALFDLIVEHVPAPAQLAQRDAPFQMLATTLGADPFIGRILTGRVEAGTVKAGETVKAL
SRDGTQIESFRVTKVLAFRGLNQQPIDLAEAGDIVSLAGMSKATVADSIVAPQVTEALPSQPIDPPTITVTFGINDSPLA
GRDGKKVQSRVIRERLMKEAESNVAIKISDTPGGEAFEVAGRGELQMGVLIENMRREGFELSISRPQVLFRDIDGVRHEP
IEEATIDVDDEYSGAVIEKITGTRRGELVEMKPAGAGKTRIVAHVPSRGLIGYHGEFLTDTRGTGVLNRVFHGWAPHKGP
IPGRRAGVLISMENGTSVAYALWNLEERGKMMIGAQADVYTGMIIGEHSRENDLEVNPLKGKKLTNVRASGTDEAVRLTT
PITLSLEEAIAYIDDDELVEVTPNAIRLRKRYLDPHERKRMARAG

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=323, Percent_Identity=30.6501547987616, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI94966754, Length=152, Percent_Identity=38.8157894736842, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI18390331, Length=144, Percent_Identity=41.6666666666667, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI25306287, Length=172, Percent_Identity=38.953488372093, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI19923640, Length=172, Percent_Identity=38.953488372093, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI25306283, Length=140, Percent_Identity=42.1428571428571, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=35.8620689655172, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=40.5405405405405, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=40.5405405405405, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=40.5405405405405, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI34147630, Length=277, Percent_Identity=27.7978339350181, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=36.7647058823529, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=36.7647058823529, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI94966752, Length=148, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=53.8971807628524, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=554, Percent_Identity=25.9927797833935, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1789738, Length=137, Percent_Identity=40.1459854014599, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789737, Length=283, Percent_Identity=28.6219081272085, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790412, Length=283, Percent_Identity=28.6219081272085, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790835, Length=144, Percent_Identity=29.8611111111111, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789559, Length=136, Percent_Identity=37.5, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=241, Percent_Identity=32.7800829875519, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556745, Length=145, Percent_Identity=42.0689655172414, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=144, Percent_Identity=45.1388888888889, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=217, Percent_Identity=30.8755760368664, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=147, Percent_Identity=35.3741496598639, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=147, Percent_Identity=35.3741496598639, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17556456, Length=282, Percent_Identity=29.0780141843972, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=35.5555555555556, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994658, Length=234, Percent_Identity=29.4871794871795, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532067, Length=269, Percent_Identity=29.368029739777, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115532065, Length=269, Percent_Identity=29.368029739777, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25141371, Length=251, Percent_Identity=27.4900398406374, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=505, Percent_Identity=26.3366336633663, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6324707, Length=202, Percent_Identity=34.1584158415842, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=202, Percent_Identity=34.1584158415842, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6323098, Length=148, Percent_Identity=39.8648648648649, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324761, Length=272, Percent_Identity=31.25, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=37.1621621621622, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=39.4366197183099, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI78706572, Length=519, Percent_Identity=27.9383429672447, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24582462, Length=144, Percent_Identity=42.3611111111111, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24585709, Length=168, Percent_Identity=34.5238095238095, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24585711, Length=168, Percent_Identity=34.5238095238095, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24585713, Length=168, Percent_Identity=34.5238095238095, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28574573, Length=137, Percent_Identity=38.6861313868613, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363316, Length=271, Percent_Identity=29.520295202952, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17864358, Length=271, Percent_Identity=29.520295202952, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221458488, Length=190, Percent_Identity=37.8947368421053, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357743, Length=173, Percent_Identity=35.8381502890173, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19921738, Length=231, Percent_Identity=27.7056277056277, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28572034, Length=296, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 65780; Mature: 65780

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRNIAIIAHVDHGKTTLVDELLKQSGTYRENQATTERAMDSNDLERERGITILAKATS
CCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEEECE
VEWKGTRINIVDTPGHADFGGEVERILSMVDGVVLLVDAAEGPMPQTKFVTSKALALGLR
EEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
PIVVLNKVDKPDAEPDRALDECFDLFANLGADDDQLDFPAMYASGRSGWADVELDGPRKD
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCEEEEECCCHHH
LSALFDLIVEHVPAPAQLAQRDAPFQMLATTLGADPFIGRILTGRVEAGTVKAGETVKAL
HHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCHHHHH
SRDGTQIESFRVTKVLAFRGLNQQPIDLAEAGDIVSLAGMSKATVADSIVAPQVTEALPS
HCCCCEEHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHCCCHHHHHCCC
QPIDPPTITVTFGINDSPLAGRDGKKVQSRVIRERLMKEAESNVAIKISDTPGGEAFEVA
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEC
GRGELQMGVLIENMRREGFELSISRPQVLFRDIDGVRHEPIEEATIDVDDEYSGAVIEKI
CCCCEEHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCEECCCCCCCCHHHHHH
TGTRRGELVEMKPAGAGKTRIVAHVPSRGLIGYHGEFLTDTRGTGVLNRVFHGWAPHKGP
CCCCCCCEEEECCCCCCCCEEEEECCCCCCEECCCCEECCCCCCHHHHHHHHCCCCCCCC
IPGRRAGVLISMENGTSVAYALWNLEERGKMMIGAQADVYTGMIIGEHSRENDLEVNPLK
CCCCCCEEEEEECCCCEEEEEEECHHHCCCEEEECCCCEEEEEEEECCCCCCCCEECCCC
GKKLTNVRASGTDEAVRLTTPITLSLEEAIAYIDDDELVEVTPNAIRLRKRYLDPHERKR
CCEECEEECCCCCCEEEEECCEEEEHHHHHHCCCCCCEEEECCHHHHHHHHHCCHHHHHH
MARAG
HHCCC
>Mature Secondary Structure
MDLRNIAIIAHVDHGKTTLVDELLKQSGTYRENQATTERAMDSNDLERERGITILAKATS
CCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCEEEEEEECE
VEWKGTRINIVDTPGHADFGGEVERILSMVDGVVLLVDAAEGPMPQTKFVTSKALALGLR
EEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
PIVVLNKVDKPDAEPDRALDECFDLFANLGADDDQLDFPAMYASGRSGWADVELDGPRKD
EEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEECCCCCCEEEEECCCHHH
LSALFDLIVEHVPAPAQLAQRDAPFQMLATTLGADPFIGRILTGRVEAGTVKAGETVKAL
HHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCCCCEECCCCHHHHH
SRDGTQIESFRVTKVLAFRGLNQQPIDLAEAGDIVSLAGMSKATVADSIVAPQVTEALPS
HCCCCEEHHHHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHCCCHHHHHCCC
QPIDPPTITVTFGINDSPLAGRDGKKVQSRVIRERLMKEAESNVAIKISDTPGGEAFEVA
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEC
GRGELQMGVLIENMRREGFELSISRPQVLFRDIDGVRHEPIEEATIDVDDEYSGAVIEKI
CCCCEEHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCEECCCCCCCCHHHHHH
TGTRRGELVEMKPAGAGKTRIVAHVPSRGLIGYHGEFLTDTRGTGVLNRVFHGWAPHKGP
CCCCCCCEEEECCCCCCCCEEEEECCCCCCEECCCCEECCCCCCHHHHHHHHCCCCCCCC
IPGRRAGVLISMENGTSVAYALWNLEERGKMMIGAQADVYTGMIIGEHSRENDLEVNPLK
CCCCCCEEEEEECCCCEEEEEEECHHHCCCEEEECCCCEEEEEEEECCCCCCCCEECCCC
GKKLTNVRASGTDEAVRLTTPITLSLEEAIAYIDDDELVEVTPNAIRLRKRYLDPHERKR
CCEECEEECCCCCCEEEEECCEEEEHHHHHHCCCCCCEEEECCHHHHHHHHHCCHHHHHH
MARAG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]