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The map label for this gene is sufC [H]

Identifier: 110679914

GI number: 110679914

Start: 2567259

End: 2568014

Strand: Reverse

Name: sufC [H]

Synonym: RD1_2694

Alternate gene names: 110679914

Gene position: 2568014-2567259 (Counterclockwise)

Preceding gene: 110679915

Following gene: 110679913

Centisome position: 62.13

GC content: 57.67

Gene sequence:

>756_bases
ATGCTGAGCATCAAAAACCTGCAGGTCAAACTGGAAGAAGAAGACAAGGAAATCCTCAAAGGCGTTGATCTTGAGATCGA
AGCAGGCAAGGTGCATGCGATCATGGGCCCGAACGGGTCGGGTAAGTCGACCCTGTCCTATGTCCTGTCGGGTAAGGACG
GCTATGAAGTCACCGGCGGATCCGCAGATCTGGAGGGCGAAGACGTGCTTGACATGGAGCCCGAAGAGCGCGCCGCGGCA
GGCCTGTTTCTCGCGTTTCAATACCCCGTGGAAATCCCCGGTGTGGGCAACATGACCTTCCTGCGCACAGCCGTGAACGC
ACAGCGCAAGGCACGTGGTGAAGAGGAAATGTCGGCGGCCGACTTCCTCAAGGCCGTGCGCGCGCGCGCAAAGGAATTGA
AGATCGACGCGGATATGCTGAAACGGCCCGTCAACGTCGGCTTTTCGGGCGGTGAGAAAAAGCGCAACGAAATCCTTCAG
ATGGCGATGCTGGAACCCAAGATGTGTATCCTGGACGAGACTGACTCCGGCCTCGACGTGGATGCGATGAAACTGGTGGC
GGAGGGTGTGAATGCGCTGCGCAATGAGGGGCGCGGGTTCCTCGTCATCACGCACTACCAGCGTCTGCTGGATCACATCA
AACCGGATGTGGTGCATATCATGGCCGATGGCAAGATCGTGAAAACGGGCGGTCCCGAACTTGCGCTTGAAGTCGAGAAC
AACGGCTACGGCAACATTCTGGCAGAGGTGGCATAA

Upstream 100 bases:

>100_bases
TTTCGGGCACGGCTGTGACCATAACGTAATCAACTTAAAGAACACGCCGCAAGGCACTGAAGTAAAACGCCTCTGTGCGA
TTAGATATAAGGGAAGAAAA

Downstream 100 bases:

>100_bases
TGGCCGAAGCAGCACTGAAAACCAGCACGACAGAGGCGCGGTTGGCGCGTCTCGCGCTGCCGGAAGGCGGTTGGACCGCA
GCCGCACGCAAGGACGCAAA

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLSIKNLQVKLEEEDKEILKGVDLEIEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTGGSADLEGEDVLDMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEEMSAADFLKAVRARAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVAEGVNALRNEGRGFLVITHYQRLLDHIKPDVVHIMADGKIVKTGGPELALEVEN
NGYGNILAEVA

Sequences:

>Translated_251_residues
MLSIKNLQVKLEEEDKEILKGVDLEIEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTGGSADLEGEDVLDMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEEMSAADFLKAVRARAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVAEGVNALRNEGRGFLVITHYQRLLDHIKPDVVHIMADGKIVKTGGPELALEVEN
NGYGNILAEVA
>Mature_251_residues
MLSIKNLQVKLEEEDKEILKGVDLEIEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTGGSADLEGEDVLDMEPEERAAA
GLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEEMSAADFLKAVRARAKELKIDADMLKRPVNVGFSGGEKKRNEILQ
MAMLEPKMCILDETDSGLDVDAMKLVAEGVNALRNEGRGFLVITHYQRLLDHIKPDVVHIMADGKIVKTGGPELALEVEN
NGYGNILAEVA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9961250, Length=220, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4505771, Length=220, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI9961252, Length=222, Percent_Identity=29.2792792792793, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI156105685, Length=221, Percent_Identity=28.5067873303167, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI42741659, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787972, Length=246, Percent_Identity=58.130081300813, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI1787370, Length=230, Percent_Identity=25.6521739130435, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790525, Length=221, Percent_Identity=29.8642533936652, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787029, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787792, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787500, Length=247, Percent_Identity=28.7449392712551, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789891, Length=225, Percent_Identity=27.5555555555556, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789672, Length=245, Percent_Identity=24.4897959183673, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788210, Length=212, Percent_Identity=26.8867924528302, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=239, Percent_Identity=27.6150627615063, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71996809, Length=230, Percent_Identity=26.9565217391304, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=227, Percent_Identity=30.3964757709251, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193211015, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533592, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=239, Percent_Identity=26.7782426778243, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=237, Percent_Identity=29.1139240506329, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=218, Percent_Identity=28.4403669724771, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=220, Percent_Identity=25.9090909090909, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324498, Length=242, Percent_Identity=28.5123966942149, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24659289, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363262, Length=234, Percent_Identity=29.4871794871795, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=234, Percent_Identity=29.4871794871795, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27255; Mature: 27255

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIKNLQVKLEEEDKEILKGVDLEIEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTGG
CCCCCCEEEEECCHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCEEECC
SADLEGEDVLDMEPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEEMSAA
CCCCCCCCCCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKAVRARAKELKIDADMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVAEGVNALRNEGRGFLVITHYQRLLDHIKPDVVHIMADGKIVKTGGPELALEVEN
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYGNILAEVA
CCCCCEEEECC
>Mature Secondary Structure
MLSIKNLQVKLEEEDKEILKGVDLEIEAGKVHAIMGPNGSGKSTLSYVLSGKDGYEVTGG
CCCCCCEEEEECCHHHHHHCCCCEEEECCEEEEEECCCCCCCCEEEEEEECCCCCEEECC
SADLEGEDVLDMEPEERAAAGLFLAFQYPVEIPGVGNMTFLRTAVNAQRKARGEEEMSAA
CCCCCCCCCCCCCCHHHHHHEEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLKAVRARAKELKIDADMLKRPVNVGFSGGEKKRNEILQMAMLEPKMCILDETDSGLDV
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCH
DAMKLVAEGVNALRNEGRGFLVITHYQRLLDHIKPDVVHIMADGKIVKTGGPELALEVEN
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEEECC
NGYGNILAEVA
CCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]