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The map label for this gene is sufS [H]

Identifier: 110679910

GI number: 110679910

Start: 2563688

End: 2564908

Strand: Reverse

Name: sufS [H]

Synonym: RD1_2689

Alternate gene names: 110679910

Gene position: 2564908-2563688 (Counterclockwise)

Preceding gene: 110679911

Following gene: 110679904

Centisome position: 62.06

GC content: 56.18

Gene sequence:

>1221_bases
ATGTATGATGTGAGCGAAATCCGCAAAGACTTCCCGATCCTCAGTCGTGAGGTCAATGGCAAGCCGCTGGTCTATCTGGA
CAATGGCGCGTCGGCCCAGAAGCCTCAGGTTGTCATTGATGCCATCAGCAACACATATGCCAACGAATATGCCAATGTGC
ATCGCGGGCTGCATTATCTGTCCAATCTGGCCACGGATAACTACGAAAGCGTGCGCGGTGTGATCGCGCGGTTCCTCAAT
GCGAAATCAGAAGATGAAATCATCCTGAATTCGGGTACGACAGAAGGCATCAATATGGTTGCCTATGGCTGGGCCATGCC
GCGTCTGCAGGCCGGTGATGAGATCATTTTGTCCGTAATGGAGCATCACGCCAATATCGTGCCCTGGCATTTCCTGCGCG
AACGCCAAGGTGTGGTGCTGAAATGGGTCGATGTGGACAGCACCGGTGCATTGGACCCCCAAGCGGTGATTGATGTGATT
GGGCCGAAGACAAAACTGGTTGCAATATCTCATCTCTCCAATGTCTTGGGGACCAAGGTTGATGTCAAAACCATCACCGC
TGAAGCGCATGCGCGCGGCGTGCCGGTCTTGGTGGATGGCTCGCAGGCGGCGGTGCACCAACCGGTGGATCTGCAGGATC
TGGGGTGCGATTTCTATGCGATCACGGGTCACAAACTCTACGGGCCGTCAGGGTCCGGTGCCATCTTTGTCAAGTCGGAA
CGGATGAAGGAAATGCGCCCGTTCATCGGTGGCGGCGATATGATCAAGGAGGTCAGCAAGGAGACGGTGATCTACAACGA
TCCGCCGCTCATGTTCGAGGCTGGCACGCCGGGGATCGTTCAGACGATCGGCTTTGGTGTCGCGCTGGAATACATGATGA
ACCTCGGGATGGAGAATATCGCAGCCTATGAGGATACGTTGCGGGATTACACGGTCGAGCGGCTCGCCGGATTGAACTGG
CTGCAGGTGCAGGGCACGACGCCGGACAAGGCAGCGATCTTCAGTTTCACGCTGGAAGGGGCGGCACATGCGCATGACGT
CTCCACCATTCTCGACAAGAAAGGGGTGGCTGTGCGCGCAGGCCAGCACTGTGTTGGCCCGTTGATGCAGCACATGGGCC
TGTCTGCGACCTGTCGCGCCTCTTTTGGATTGTATAACACCAAAGAGGAAGTGGACGTCTTTGTCGAAGCCCTGGAACTG
GCGCATGATCTGTTTGCGTGA

Upstream 100 bases:

>100_bases
CGGGCGGTTGGCGTGTTGTTTCTGGGGGCCGTTGCCTTGATGGCAATCCTGACTTTCTTGCTATCCATGATCGGCGTGTC
CGCCGTCGGAGTACCTTTGA

Downstream 100 bases:

>100_bases
TCTGCGCGCGGTGATTTAGCAATTGCAGGAGCGATACGCCCGGTTTATACCGCATGGCGTGACGCCGACCTGTATTGGCA
AGTGGTACGAAGAGACAAAA

Product: cysteine desulfurase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MYDVSEIRKDFPILSREVNGKPLVYLDNGASAQKPQVVIDAISNTYANEYANVHRGLHYLSNLATDNYESVRGVIARFLN
AKSEDEIILNSGTTEGINMVAYGWAMPRLQAGDEIILSVMEHHANIVPWHFLRERQGVVLKWVDVDSTGALDPQAVIDVI
GPKTKLVAISHLSNVLGTKVDVKTITAEAHARGVPVLVDGSQAAVHQPVDLQDLGCDFYAITGHKLYGPSGSGAIFVKSE
RMKEMRPFIGGGDMIKEVSKETVIYNDPPLMFEAGTPGIVQTIGFGVALEYMMNLGMENIAAYEDTLRDYTVERLAGLNW
LQVQGTTPDKAAIFSFTLEGAAHAHDVSTILDKKGVAVRAGQHCVGPLMQHMGLSATCRASFGLYNTKEEVDVFVEALEL
AHDLFA

Sequences:

>Translated_406_residues
MYDVSEIRKDFPILSREVNGKPLVYLDNGASAQKPQVVIDAISNTYANEYANVHRGLHYLSNLATDNYESVRGVIARFLN
AKSEDEIILNSGTTEGINMVAYGWAMPRLQAGDEIILSVMEHHANIVPWHFLRERQGVVLKWVDVDSTGALDPQAVIDVI
GPKTKLVAISHLSNVLGTKVDVKTITAEAHARGVPVLVDGSQAAVHQPVDLQDLGCDFYAITGHKLYGPSGSGAIFVKSE
RMKEMRPFIGGGDMIKEVSKETVIYNDPPLMFEAGTPGIVQTIGFGVALEYMMNLGMENIAAYEDTLRDYTVERLAGLNW
LQVQGTTPDKAAIFSFTLEGAAHAHDVSTILDKKGVAVRAGQHCVGPLMQHMGLSATCRASFGLYNTKEEVDVFVEALEL
AHDLFA
>Mature_406_residues
MYDVSEIRKDFPILSREVNGKPLVYLDNGASAQKPQVVIDAISNTYANEYANVHRGLHYLSNLATDNYESVRGVIARFLN
AKSEDEIILNSGTTEGINMVAYGWAMPRLQAGDEIILSVMEHHANIVPWHFLRERQGVVLKWVDVDSTGALDPQAVIDVI
GPKTKLVAISHLSNVLGTKVDVKTITAEAHARGVPVLVDGSQAAVHQPVDLQDLGCDFYAITGHKLYGPSGSGAIFVKSE
RMKEMRPFIGGGDMIKEVSKETVIYNDPPLMFEAGTPGIVQTIGFGVALEYMMNLGMENIAAYEDTLRDYTVERLAGLNW
LQVQGTTPDKAAIFSFTLEGAAHAHDVSTILDKKGVAVRAGQHCVGPLMQHMGLSATCRASFGLYNTKEEVDVFVEALEL
AHDLFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=390, Percent_Identity=25.6410256410256, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI156713448, Length=324, Percent_Identity=28.0864197530864, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787970, Length=406, Percent_Identity=47.7832512315271, Blast_Score=380, Evalue=1e-106,
Organism=Escherichia coli, GI1789175, Length=408, Percent_Identity=37.9901960784314, Blast_Score=293, Evalue=9e-81,
Organism=Escherichia coli, GI48994898, Length=400, Percent_Identity=26.75, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=240, Percent_Identity=28.75, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17533177, Length=332, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211090, Length=374, Percent_Identity=21.6577540106952, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319831, Length=391, Percent_Identity=25.5754475703325, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129463, Length=395, Percent_Identity=26.3291139240506, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44286; Mature: 44286

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDVSEIRKDFPILSREVNGKPLVYLDNGASAQKPQVVIDAISNTYANEYANVHRGLHYL
CCCHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
SNLATDNYESVRGVIARFLNAKSEDEIILNSGTTEGINMVAYGWAMPRLQAGDEIILSVM
HHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHH
EHHANIVPWHFLRERQGVVLKWVDVDSTGALDPQAVIDVIGPKTKLVAISHLSNVLGTKV
HHCCCCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHCCCE
DVKTITAEAHARGVPVLVDGSQAAVHQPVDLQDLGCDFYAITGHKLYGPSGSGAIFVKSE
EEEEEEEHHHHCCCCEEEECCHHHHCCCCCHHHCCCCEEEEECCEEECCCCCCEEEEEHH
RMKEMRPFIGGGDMIKEVSKETVIYNDPPLMFEAGTPGIVQTIGFGVALEYMMNLGMENI
HHHHHCCCCCCHHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHH
AAYEDTLRDYTVERLAGLNWLQVQGTTPDKAAIFSFTLEGAAHAHDVSTILDKKGVAVRA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEC
GQHCVGPLMQHMGLSATCRASFGLYNTKEEVDVFVEALELAHDLFA
CCHHHHHHHHHCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYDVSEIRKDFPILSREVNGKPLVYLDNGASAQKPQVVIDAISNTYANEYANVHRGLHYL
CCCHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
SNLATDNYESVRGVIARFLNAKSEDEIILNSGTTEGINMVAYGWAMPRLQAGDEIILSVM
HHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHH
EHHANIVPWHFLRERQGVVLKWVDVDSTGALDPQAVIDVIGPKTKLVAISHLSNVLGTKV
HHCCCCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHCCCE
DVKTITAEAHARGVPVLVDGSQAAVHQPVDLQDLGCDFYAITGHKLYGPSGSGAIFVKSE
EEEEEEEHHHHCCCCEEEECCHHHHCCCCCHHHCCCCEEEEECCEEECCCCCCEEEEEHH
RMKEMRPFIGGGDMIKEVSKETVIYNDPPLMFEAGTPGIVQTIGFGVALEYMMNLGMENI
HHHHHCCCCCCHHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHH
AAYEDTLRDYTVERLAGLNWLQVQGTTPDKAAIFSFTLEGAAHAHDVSTILDKKGVAVRA
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEC
GQHCVGPLMQHMGLSATCRASFGLYNTKEEVDVFVEALELAHDLFA
CCHHHHHHHHHCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]