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The map label for this gene is frr

Identifier: 110679817

GI number: 110679817

Start: 2470644

End: 2471207

Strand: Direct

Name: frr

Synonym: RD1_2586

Alternate gene names: 110679817

Gene position: 2470644-2471207 (Clockwise)

Preceding gene: 110679816

Following gene: 110679818

Centisome position: 59.78

GC content: 56.38

Gene sequence:

>564_bases
ATGTCAGAAGACTTCATGCTGGACACAGACGATATCGAACGCCGTATGGATGGCGCCATTTCATCGTTGAAGACGGAGTT
TGCATCCCTGCGGACCGGACGGGCCTCCGCTTCTATGCTGGAGCCGGTGATGGTGGATGCCTATGGTCAGCGCACGCCGA
TCAATCAGGTAGGCACCGTCAACGTGCCGGAGCCGCGCATGGTCACCATCAACGTCTGGGACAAGGGGCTGGTCGGCAAG
GTTGAAAAAGCCATTCGCGAAAGCGGTCTTGGCATAAACCCGCAATTGAACGGCACGATCATCATGTTGCCGATCCCTGA
ATTGAATGAGGAACGCCGCCGCGAATTGAGCAAGGTCGCCGGGCAATATGCCGAACATGCCCGCGTTTCCATTCGCAATA
TCCGGCGTGACGGTATGGATCAGATCAAGAAAGCCAAAGCGGATGGCCTGTCGGAGGACGACCAGAAGCTCTGGGAAGGC
GAGGTTCAGGAAATCACCGACCGCTACATCAAGGGCATCGACGACCAGTTGGCGACAAAGCAAGCGGAAATCATGCAGGT
CTGA

Upstream 100 bases:

>100_bases
CGCGGGTTCAGGACTAGCGGCGCCTTCGGACACGGCGGCGCTGTACACTCCGCACCCGAGCAGATTATAACTCCCCAAAT
GTACGAAAGGGCAGTGAGCA

Downstream 100 bases:

>100_bases
CGCGCAAACACGAACAGGCGCGGCGAAAGTCCCGGAATTACGGGCTGTGACATCGAAAAATGCCCCTGCTTTGGCCGCGT
TAAAGGTGATTTTAAAGATT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSEDFMLDTDDIERRMDGAISSLKTEFASLRTGRASASMLEPVMVDAYGQRTPINQVGTVNVPEPRMVTINVWDKGLVGK
VEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELSKVAGQYAEHARVSIRNIRRDGMDQIKKAKADGLSEDDQKLWEG
EVQEITDRYIKGIDDQLATKQAEIMQV

Sequences:

>Translated_187_residues
MSEDFMLDTDDIERRMDGAISSLKTEFASLRTGRASASMLEPVMVDAYGQRTPINQVGTVNVPEPRMVTINVWDKGLVGK
VEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELSKVAGQYAEHARVSIRNIRRDGMDQIKKAKADGLSEDDQKLWEG
EVQEITDRYIKGIDDQLATKQAEIMQV
>Mature_186_residues
SEDFMLDTDDIERRMDGAISSLKTEFASLRTGRASASMLEPVMVDAYGQRTPINQVGTVNVPEPRMVTINVWDKGLVGKV
EKAIRESGLGINPQLNGTIIMLPIPELNEERRRELSKVAGQYAEHARVSIRNIRRDGMDQIKKAKADGLSEDDQKLWEGE
VQEITDRYIKGIDDQLATKQAEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=29.8342541436464, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI291042689, Length=155, Percent_Identity=32.9032258064516, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=45.1977401129944, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24661488, Length=181, Percent_Identity=27.0718232044199, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ROSDO (Q166F5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682824.1
- ProteinModelPortal:   Q166F5
- SMR:   Q166F5
- STRING:   Q166F5
- GeneID:   4195026
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2586
- NMPDR:   fig|375451.6.peg.2403
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q166F5
- ProtClustDB:   PRK00083
- BioCyc:   RDEN375451:RD1_2586-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21000; Mature: 20869

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDFMLDTDDIERRMDGAISSLKTEFASLRTGRASASMLEPVMVDAYGQRTPINQVGTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
NVPEPRMVTINVWDKGLVGKVEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELSKVA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
GQYAEHARVSIRNIRRDGMDQIKKAKADGLSEDDQKLWEGEVQEITDRYIKGIDDQLATK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QAEIMQV
HHHHHCC
>Mature Secondary Structure 
SEDFMLDTDDIERRMDGAISSLKTEFASLRTGRASASMLEPVMVDAYGQRTPINQVGTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
NVPEPRMVTINVWDKGLVGKVEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELSKVA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
GQYAEHARVSIRNIRRDGMDQIKKAKADGLSEDDQKLWEGEVQEITDRYIKGIDDQLATK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QAEIMQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA