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The map label for this gene is putR [H]

Identifier: 110679748

GI number: 110679748

Start: 2396453

End: 2396914

Strand: Direct

Name: putR [H]

Synonym: RD1_2510

Alternate gene names: 110679748

Gene position: 2396453-2396914 (Clockwise)

Preceding gene: 110679745

Following gene: 110679749

Centisome position: 57.98

GC content: 57.58

Gene sequence:

>462_bases
ATGGATATCGACCGGTTTGATCGTGCGATCCTGTCCGTACTGGCCGAAGATGGCCGGATCAGCATCACCGATCTGTCCAA
GCGGATCGGCTTGTCCAAATCGCCCACGCAAGCGCGTCTGCGGCGGCTCGAACAAAGTGGTGTCGTGATCGGATATCGGG
CCTTGCTGGACCCGATCCGATTGGGCTTGGATCACGTGGCTTTCGTCGAAGTGCGCCTGAGTGATACCAGAGAGGCGGCG
TTGAATGCGTTCAACCTCGCGATTGCGCGGGTGCCGCAGATCGAGCAAGCCCATATGATTGCTGGGAATTTTGACTATCT
TCTGAAGGTGCGCACGCGCGACATGTCTGATTACCGCCGCTTTCTGGGCGAGACGATCTCGGAGCTGCCCCATGTCGAAA
ACACCTCCACCTATGTGGCGATGCAGGCGGTGAAGGAAACAATGCTGGCGGAAAAGGGTTGA

Upstream 100 bases:

>100_bases
TCACTAGATTACCACGATCTGATAAGTCATATTGCCTTTTCAGCGTGGCAGAATGAGAAAAAAGATGGAATTTTTATCAG
GTGACAGGACAAATGAGCAA

Downstream 100 bases:

>100_bases
CGCGCGACGGCGGCGGGTCATTCTGCCAGACATGAAACTGAAACTCATCGCTCTTTGTTTTTTCGCGGCGCCCGCCTTTG
CGCAATGTCCGCCGGTGTCG

Product: proline dehydrogenase transcriptional activator, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MDIDRFDRAILSVLAEDGRISITDLSKRIGLSKSPTQARLRRLEQSGVVIGYRALLDPIRLGLDHVAFVEVRLSDTREAA
LNAFNLAIARVPQIEQAHMIAGNFDYLLKVRTRDMSDYRRFLGETISELPHVENTSTYVAMQAVKETMLAEKG

Sequences:

>Translated_153_residues
MDIDRFDRAILSVLAEDGRISITDLSKRIGLSKSPTQARLRRLEQSGVVIGYRALLDPIRLGLDHVAFVEVRLSDTREAA
LNAFNLAIARVPQIEQAHMIAGNFDYLLKVRTRDMSDYRRFLGETISELPHVENTSTYVAMQAVKETMLAEKG
>Mature_153_residues
MDIDRFDRAILSVLAEDGRISITDLSKRIGLSKSPTQARLRRLEQSGVVIGYRALLDPIRLGLDHVAFVEVRLSDTREAA
LNAFNLAIARVPQIEQAHMIAGNFDYLLKVRTRDMSDYRRFLGETISELPHVENTSTYVAMQAVKETMLAEKG

Specific function: Transcriptional activator of the putA gene in response to proline [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=47.945205479452, Blast_Score=146, Evalue=7e-37,
Organism=Escherichia coli, GI87081742, Length=145, Percent_Identity=31.0344827586207, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=24.4755244755245, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17231; Mature: 17231

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDRFDRAILSVLAEDGRISITDLSKRIGLSKSPTQARLRRLEQSGVVIGYRALLDPIR
CCHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHH
LGLDHVAFVEVRLSDTREAALNAFNLAIARVPQIEQAHMIAGNFDYLLKVRTRDMSDYRR
HCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHEEECCCEEEEEEECCCHHHHHH
FLGETISELPHVENTSTYVAMQAVKETMLAEKG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIDRFDRAILSVLAEDGRISITDLSKRIGLSKSPTQARLRRLEQSGVVIGYRALLDPIR
CCHHHHHHHHHHHHHCCCCEEHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHH
LGLDHVAFVEVRLSDTREAALNAFNLAIARVPQIEQAHMIAGNFDYLLKVRTRDMSDYRR
HCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHEEECCCEEEEEEECCCHHHHHH
FLGETISELPHVENTSTYVAMQAVKETMLAEKG
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606160 [H]