BacMap

Definition	Roseobacter denitrificans OCh 114, complete genome.
Accession	NC_008209
Length	4,133,097

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The map label for this gene is fixR [H]

Identifier: 110679593

GI number: 110679593

Start: 2237337

End: 2238092

Strand: Reverse

Name: fixR [H]

Synonym: RD1_2338

Alternate gene names: 110679593

Gene position: 2238092-2237337 (Counterclockwise)

Preceding gene: 110679596

Following gene: 110679591

Centisome position: 54.15

GC content: 64.02

Gene sequence:

>756_bases
ATGAGCCGCTTTGAGCCGACAACAAAACCGATCGTTGCCGTCACCGGGGCCAGTCGTGGCATCGGGCACGCCATCGTCAA
GAAGTTCTACGAGGATGGCTGGGACGTGCTGACGCTGGCGCGCACCCCCTTCAGCCAGGTGTGCCCATGGGCGGAAGGCA
TCGTGCATCACATCGAGACGGACCTGTCGGATGAAGCCTCTGTGCGGGCGGCGGCGCTGAACCTTCGCGACCGCCTCGGG
GGCCGTGGGCTGGATGCGCTGGTGAACAACGCCGGAATCTCGCCCAAGGATGCGGCCGGCGGGCGTCTGCTGGCCACGCA
AACCGAGATCGAGGTCTTTCGCAGAGTGGAGATGGTCAATCTGATCGCGCCGCTCATTCTGGTGCGCGAACTCCTTGACC
CGTTGATGCAGGCGGGTGGGTCGGTCGTGAATGTCTCCTCCATCGCCGCCACGCAAGTGCACCCGTTTGCGGGCGCGGCC
TATGCGATTTCCAAGGCCGGGCTGTCCGCGCTTACGCGCGAACTGGCGCATGAATTGGCCGCCAAGGGCGTGCGCGTCAA
TGCCGTCTCGCCCGGAGAGATCGAAACCTCGATCCTGTCACCGGGCACCAGCGAAGTCGTCAGCCGGGATGTGCCGATGA
AACGGCTCGGTCATCCCGGAGAGGTTGCGGATGTGGTGGCTTTCCTGTGCTCAAAGGCATCATCCTACGTGAACGGCGCT
GAAATCCCGATCAACGGCGGGCAGCATCTGGCGTGA

Upstream 100 bases:

>100_bases
CGGCATCAGGCGGCGGGACATTGCGTTCGCGCGCCTGGCAACTTTGGTATTTACCCGGTGAGACAAAAAGACATCGCTGA
CCAGCATGCGGGAGCACGCC

Downstream 100 bases:

>100_bases
TCACGCCACCTCCGATGCGAAGGTTTCAAGGCTTTTCTCAACGATATCCACCATGTCGGAAACCTGTTGCTGCGTGATGA
TCAGCGGCGGGCAAAATGCC

Product: oxidoreductase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSRFEPTTKPIVAVTGASRGIGHAIVKKFYEDGWDVLTLARTPFSQVCPWAEGIVHHIETDLSDEASVRAAALNLRDRLG
GRGLDALVNNAGISPKDAAGGRLLATQTEIEVFRRVEMVNLIAPLILVRELLDPLMQAGGSVVNVSSIAATQVHPFAGAA
YAISKAGLSALTRELAHELAAKGVRVNAVSPGEIETSILSPGTSEVVSRDVPMKRLGHPGEVADVVAFLCSKASSYVNGA
EIPINGGQHLA

Sequences:

>Translated_251_residues
MSRFEPTTKPIVAVTGASRGIGHAIVKKFYEDGWDVLTLARTPFSQVCPWAEGIVHHIETDLSDEASVRAAALNLRDRLG
GRGLDALVNNAGISPKDAAGGRLLATQTEIEVFRRVEMVNLIAPLILVRELLDPLMQAGGSVVNVSSIAATQVHPFAGAA
YAISKAGLSALTRELAHELAAKGVRVNAVSPGEIETSILSPGTSEVVSRDVPMKRLGHPGEVADVVAFLCSKASSYVNGA
EIPINGGQHLA
>Mature_250_residues
SRFEPTTKPIVAVTGASRGIGHAIVKKFYEDGWDVLTLARTPFSQVCPWAEGIVHHIETDLSDEASVRAAALNLRDRLGG
RGLDALVNNAGISPKDAAGGRLLATQTEIEVFRRVEMVNLIAPLILVRELLDPLMQAGGSVVNVSSIAATQVHPFAGAAY
AISKAGLSALTRELAHELAAKGVRVNAVSPGEIETSILSPGTSEVVSRDVPMKRLGHPGEVADVVAFLCSKASSYVNGAE
IPINGGQHLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=263, Percent_Identity=32.319391634981, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=34.6613545816733, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=30.1526717557252, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=27.8195488721804, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI15277342, Length=140, Percent_Identity=37.8571428571429, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI59889578, Length=203, Percent_Identity=29.5566502463054, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=30.952380952381, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI22507405, Length=229, Percent_Identity=30.1310043668122, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=32.0388349514563, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=32.4607329842932, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI40548397, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI214010158, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI214010156, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI22758144, Length=205, Percent_Identity=25.3658536585366, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI50726952, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI19743808, Length=190, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4504503, Length=231, Percent_Identity=28.1385281385281, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI2367175, Length=259, Percent_Identity=33.976833976834, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=32.9365079365079, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.2252964426877, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=33.1967213114754, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=26.7716535433071, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789208, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=174, Percent_Identity=28.735632183908, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=33.4558823529412, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=35.1239669421488, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=274, Percent_Identity=33.2116788321168, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=274, Percent_Identity=32.8467153284672, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=30.8823529411765, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=30.6569343065693, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=31.3653136531365, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=31.3653136531365, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=30.1470588235294, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.7153558052434, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=30.7971014492754, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=30.8823529411765, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=32.0158102766798, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=31.1111111111111, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=32.046332046332, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=31.3868613138686, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=279, Percent_Identity=29.3906810035842, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=30.7392996108949, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=208, Percent_Identity=32.6923076923077, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=32.3886639676113, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=30.859375, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=29.811320754717, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=31.8007662835249, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=30.46875, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=29.2592592592593, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.8625954198473, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=28.5171102661597, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=26.3736263736264, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=28.4644194756554, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=145, Percent_Identity=33.1034482758621, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559962, Length=209, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=144, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=37.4517374517375, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=33.8775510204082, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=33.203125, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.9317269076305, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644337, Length=204, Percent_Identity=35.7843137254902, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=32.9317269076305, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=32.8358208955224, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=32.9457364341085, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26372; Mature: 26240

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFEPTTKPIVAVTGASRGIGHAIVKKFYEDGWDVLTLARTPFSQVCPWAEGIVHHIET
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHCCHHHHHHHHHHH
DLSDEASVRAAALNLRDRLGGRGLDALVNNAGISPKDAAGGRLLATQTEIEVFRRVEMVN
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
LIAPLILVRELLDPLMQAGGSVVNVSSIAATQVHPFAGAAYAISKAGLSALTRELAHELA
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKGVRVNAVSPGEIETSILSPGTSEVVSRDVPMKRLGHPGEVADVVAFLCSKASSYVNGA
HCCEEEECCCCCCCHHHHCCCCHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCC
EIPINGGQHLA
CCCCCCCCCCC
>Mature Secondary Structure 
SRFEPTTKPIVAVTGASRGIGHAIVKKFYEDGWDVLTLARTPFSQVCPWAEGIVHHIET
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHCCHHHHHHHHHHH
DLSDEASVRAAALNLRDRLGGRGLDALVNNAGISPKDAAGGRLLATQTEIEVFRRVEMVN
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
LIAPLILVRELLDPLMQAGGSVVNVSSIAATQVHPFAGAAYAISKAGLSALTRELAHELA
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKGVRVNAVSPGEIETSILSPGTSEVVSRDVPMKRLGHPGEVADVVAFLCSKASSYVNGA
HCCEEEECCCCCCCHHHHCCCCHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCC
EIPINGGQHLA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3313281; 11157954; 12597275 [H]