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The map label for this gene is dctD [H]

Identifier: 110679531

GI number: 110679531

Start: 2166257

End: 2167591

Strand: Direct

Name: dctD [H]

Synonym: RD1_2266

Alternate gene names: 110679531

Gene position: 2166257-2167591 (Clockwise)

Preceding gene: 110679530

Following gene: 110679532

Centisome position: 52.41

GC content: 60.07

Gene sequence:

>1335_bases
ATGACACAAGCCATGAAAATCGCGATTGTCGATGACGAACAGGACATGCGCCAATCCATCAGCCAGTGGCTGGCCCTTTC
GGGGTATGACACGGAAACCTTCGGCAGTGCCGAGGATGCGTTGAAAGTGCTCGGGCCGGAGTATCCGGGGATCGTCATTT
CCGATATCCGAATGCCGGGCATGGATGGGATGCAGTTCCTCAAGAAGCTGATGGGCAATGATTCTGCCCTGCCGGTGATC
ATGATTACGGGGCATGGCGATGTGCCGATGGCGGTTGAGGCCATGCGCGTCGGCGCCTTTGATTTTCTGGAAAAACCGTT
CAACCCGGACCGCATGTCGGACCTTGCCAAAAAGGCGACAGGTGCGAGACGTCTGGTGATGGACAACCGCGCATTGCGGC
GGGAACTTTCCGACGGCACCCAGTTGATGAGCAAGCTCATCGGGCAAAGCCCGGTCATGGAGCGGCTGCGCGAAGATATC
CTCGATCTGGGGCAGGCGGATGGCCATGTGCTGATCGATGGTGAAACCGGAACCGGTAAAACGCTGGTGGCCCATGCCTT
GCATGCGGTGGGCAGCCGGGCGGGCAAGAAGTTCGTGCTGGTCAGTTGCAGCGCCTTTGAAGAGGACGCGCTGGCCAAAC
GCCTGTTCGGGCCGATGATGCCGGAGGATGCGCAACTGCCCGCCATGGAAGAGGCGCGCGGCGGCACCTTGGTGCTGGAA
GACATTGAGGCGCTGTCAGAAACGATGCAAGCCCGCCTGCTCAGTGTGATAAACGAGCAGGGTACCCCGGCAGAGACGCG
GCTGGTCGCGATCTCGAACCTGCAGGAAGCGGGGCGCACCTCCGAGGATGCGTTGCGCTCTGATCTGTTCTACCGCATCG
CGGCATTGCGCATCACGGTGCCACCTCTGCGCATGCGGGGCGAAGATATCCTCACCCTCTTCACCCGTCTGAGCGAACAG
TTCGCCGAAGAATACGGCTGCGACACACCGCAGGTGACGGCACAGGAGGCTGCGCAGCTGTTGCAGGCGCCCTGGCCGGG
CAATGTGCGCCAGCTGATCAACCTCGCGGAACGCGCGGTGCTGCAGTCACGGCGCGGGGCAGGGACCATATCATCGCTGC
TGATGAACGATCATGAGGACATGCAGCCTGTGATGACGACCGAAGGCAAACCGCTGAAAGAATACGTCGAAGCCTTCGAG
CGGATGCTGATCGACAATACCATGCGCCGACATCGCGGCTCTATCGCGAGTGTGATGGATGAACTATGCCTGCCCAGACG
CACGCTGAACGAAAAAATGGCGAAATATGGCCTGCAACGCTCAGATTACCTCTGA

Upstream 100 bases:

>100_bases
AAGGCTTACAGCGCGCAATGGCCAGCAGGGCGGCGCGGTTTTTGAAATGCAATTGCCGATCCTAAGCGGCGAACCAGCGA
AACAAGCGGCGGAGTAGACA

Downstream 100 bases:

>100_bases
AACCGGGAATTTGATCAGTAAATCCGACGGTTTAGTGGATTCAATTCAGGGTTGAGGCAGGTAAATGTCGATTGACCATT
GTGTTTTTCAGGCATGTAGC

Product: C4-dicarboxylate transport transcriptional regulatory protein DctD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTQAMKIAIVDDEQDMRQSISQWLALSGYDTETFGSAEDALKVLGPEYPGIVISDIRMPGMDGMQFLKKLMGNDSALPVI
MITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSDLAKKATGARRLVMDNRALRRELSDGTQLMSKLIGQSPVMERLREDI
LDLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCSAFEEDALAKRLFGPMMPEDAQLPAMEEARGGTLVLE
DIEALSETMQARLLSVINEQGTPAETRLVAISNLQEAGRTSEDALRSDLFYRIAALRITVPPLRMRGEDILTLFTRLSEQ
FAEEYGCDTPQVTAQEAAQLLQAPWPGNVRQLINLAERAVLQSRRGAGTISSLLMNDHEDMQPVMTTEGKPLKEYVEAFE
RMLIDNTMRRHRGSIASVMDELCLPRRTLNEKMAKYGLQRSDYL

Sequences:

>Translated_444_residues
MTQAMKIAIVDDEQDMRQSISQWLALSGYDTETFGSAEDALKVLGPEYPGIVISDIRMPGMDGMQFLKKLMGNDSALPVI
MITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSDLAKKATGARRLVMDNRALRRELSDGTQLMSKLIGQSPVMERLREDI
LDLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCSAFEEDALAKRLFGPMMPEDAQLPAMEEARGGTLVLE
DIEALSETMQARLLSVINEQGTPAETRLVAISNLQEAGRTSEDALRSDLFYRIAALRITVPPLRMRGEDILTLFTRLSEQ
FAEEYGCDTPQVTAQEAAQLLQAPWPGNVRQLINLAERAVLQSRRGAGTISSLLMNDHEDMQPVMTTEGKPLKEYVEAFE
RMLIDNTMRRHRGSIASVMDELCLPRRTLNEKMAKYGLQRSDYL
>Mature_443_residues
TQAMKIAIVDDEQDMRQSISQWLALSGYDTETFGSAEDALKVLGPEYPGIVISDIRMPGMDGMQFLKKLMGNDSALPVIM
ITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSDLAKKATGARRLVMDNRALRRELSDGTQLMSKLIGQSPVMERLREDIL
DLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCSAFEEDALAKRLFGPMMPEDAQLPAMEEARGGTLVLED
IEALSETMQARLLSVINEQGTPAETRLVAISNLQEAGRTSEDALRSDLFYRIAALRITVPPLRMRGEDILTLFTRLSEQF
AEEYGCDTPQVTAQEAAQLLQAPWPGNVRQLINLAERAVLQSRRGAGTISSLLMNDHEDMQPVMTTEGKPLKEYVEAFER
MLIDNTMRRHRGSIASVMDELCLPRRTLNEKMAKYGLQRSDYL

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=469, Percent_Identity=31.5565031982942, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1790299, Length=469, Percent_Identity=30.7036247334755, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1790437, Length=457, Percent_Identity=30.4157549234136, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1788905, Length=452, Percent_Identity=28.9823008849558, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787583, Length=323, Percent_Identity=29.7213622291022, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1789087, Length=342, Percent_Identity=30.7017543859649, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082117, Length=334, Percent_Identity=30.8383233532934, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786524, Length=274, Percent_Identity=33.9416058394161, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=30.1538461538462, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87082152, Length=303, Percent_Identity=31.6831683168317, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=32.4675324675325, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=29.1095890410959, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789809, Length=109, Percent_Identity=29.3577981651376, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787487, Length=109, Percent_Identity=33.9449541284404, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787375, Length=161, Percent_Identity=25.4658385093168, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789828, Length=299, Percent_Identity=25.752508361204, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49132; Mature: 49001

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAMKIAIVDDEQDMRQSISQWLALSGYDTETFGSAEDALKVLGPEYPGIVISDIRMPG
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
MDGMQFLKKLMGNDSALPVIMITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSDLAKKAT
CHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GARRLVMDNRALRRELSDGTQLMSKLIGQSPVMERLREDILDLGQADGHVLIDGETGTGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TLVAHALHAVGSRAGKKFVLVSCSAFEEDALAKRLFGPMMPEDAQLPAMEEARGGTLVLE
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEHH
DIEALSETMQARLLSVINEQGTPAETRLVAISNLQEAGRTSEDALRSDLFYRIAALRITV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEC
PPLRMRGEDILTLFTRLSEQFAEEYGCDTPQVTAQEAAQLLQAPWPGNVRQLINLAERAV
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQSRRGAGTISSLLMNDHEDMQPVMTTEGKPLKEYVEAFERMLIDNTMRRHRGSIASVMD
HHHCCCCHHHHHHHHCCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELCLPRRTLNEKMAKYGLQRSDYL
HHHCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TQAMKIAIVDDEQDMRQSISQWLALSGYDTETFGSAEDALKVLGPEYPGIVISDIRMPG
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
MDGMQFLKKLMGNDSALPVIMITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSDLAKKAT
CHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GARRLVMDNRALRRELSDGTQLMSKLIGQSPVMERLREDILDLGQADGHVLIDGETGTGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TLVAHALHAVGSRAGKKFVLVSCSAFEEDALAKRLFGPMMPEDAQLPAMEEARGGTLVLE
HHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEHH
DIEALSETMQARLLSVINEQGTPAETRLVAISNLQEAGRTSEDALRSDLFYRIAALRITV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEC
PPLRMRGEDILTLFTRLSEQFAEEYGCDTPQVTAQEAAQLLQAPWPGNVRQLINLAERAV
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQSRRGAGTISSLLMNDHEDMQPVMTTEGKPLKEYVEAFERMLIDNTMRRHRGSIASVMD
HHHCCCCHHHHHHHHCCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELCLPRRTLNEKMAKYGLQRSDYL
HHHCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]