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The map label for this gene is purQ

Identifier: 110679529

GI number: 110679529

Start: 2163787

End: 2164455

Strand: Direct

Name: purQ

Synonym: RD1_2264

Alternate gene names: 110679529

Gene position: 2163787-2164455 (Clockwise)

Preceding gene: 110679528

Following gene: 110679530

Centisome position: 52.35

GC content: 61.88

Gene sequence:

>669_bases
ATGCACGCGGCGGTCGTTGTCTTTCCCGGGTCCAACTGTGATCGCGATCTTGCCGTCGCCTTTGAGGCGGCTGGCGCACA
GGTCACCAAGGTCTGGCACAAGGATACCGACCTGCCCGAAGGCGTCGATATCATCGGTATTCCGGGCGGATTTTCCTTTG
GCGATTACCTGCGTTGCGGGGCCATCGCCGCAAACTCGCCGATTTGCCGATCCGTCGCAGCACATGCGGAGCGGGGGGGC
TACGTCATCGGCATCTGCAACGGGTTTCAGGTGCTCACCGAAACCGGGTTGTTGCCGGGCGCGTTGCTGCGCAATGCCGG
GTTGAAATACATCTGCAAAACCGTCGCGCTCAAGGTTGAGACATCTGCATCCGCCTTTACCGAAGGGTACACCGCCGGGG
ATACCATCAGTATTCCAATCGCCCATCACGACGGCAATTACTTTGCCGATGATGAGACGATCGCGCGTCTTCAGGGCGAA
GACCGCGTCGCTTTTACCTATGAGGACACGCCCAACGGTGCCAAAGCGGATATCGCGGGCATCCTGTCGTCAAACCGCCG
GGTTCTTGGCATGATGCCGCACCCGGAACGCGCGGCGGATGCCGGGCATGGCGGGACGGATGGGCAGGCGCTCTTCCGCG
CATTGACGGGCGCGCTGGCGGCGGTGTGA

Upstream 100 bases:

>100_bases
TTGATCTGGCCGAAGGCACGACCGAAGCGGACGTGAGCGCGATGTGTGAAAAGCTGCTGGCCAATACGGTGATCGAATCC
TACTCGGTGGAGATTTCCTG

Downstream 100 bases:

>100_bases
CTTGAGCCGATACGCGCCTTTGGCGTAAGCTGCTTTCATGGAAGCCGAGCTTCAATCAAAAGAGCCGAACCCGATCAGCT
CATGGCGGGTGCGCATGGCT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MHAAVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDIIGIPGGFSFGDYLRCGAIAANSPICRSVAAHAERGG
YVIGICNGFQVLTETGLLPGALLRNAGLKYICKTVALKVETSASAFTEGYTAGDTISIPIAHHDGNYFADDETIARLQGE
DRVAFTYEDTPNGAKADIAGILSSNRRVLGMMPHPERAADAGHGGTDGQALFRALTGALAAV

Sequences:

>Translated_222_residues
MHAAVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDIIGIPGGFSFGDYLRCGAIAANSPICRSVAAHAERGG
YVIGICNGFQVLTETGLLPGALLRNAGLKYICKTVALKVETSASAFTEGYTAGDTISIPIAHHDGNYFADDETIARLQGE
DRVAFTYEDTPNGAKADIAGILSSNRRVLGMMPHPERAADAGHGGTDGQALFRALTGALAAV
>Mature_222_residues
MHAAVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDIIGIPGGFSFGDYLRCGAIAANSPICRSVAAHAERGG
YVIGICNGFQVLTETGLLPGALLRNAGLKYICKTVALKVETSASAFTEGYTAGDTISIPIAHHDGNYFADDETIARLQGE
DRVAFTYEDTPNGAKADIAGILSSNRRVLGMMPHPERAADAGHGGTDGQALFRALTGALAAV

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=223, Percent_Identity=28.6995515695067, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=232, Percent_Identity=30.6034482758621, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582111, Length=234, Percent_Identity=29.0598290598291, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582109, Length=234, Percent_Identity=29.0598290598291, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17137292, Length=234, Percent_Identity=29.0598290598291, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_ROSDO (Q167J3)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682536.1
- ProteinModelPortal:   Q167J3
- SMR:   Q167J3
- STRING:   Q167J3
- GeneID:   4196494
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2264
- NMPDR:   fig|375451.6.peg.2112
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- BioCyc:   RDEN375451:RD1_2264-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 23105; Mature: 23105

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 86-86 ACT_SITE 194-194 ACT_SITE 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAAVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDIIGIPGGFSFGDYLRCG
CCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHC
AIAANSPICRSVAAHAERGGYVIGICNGFQVLTETGLLPGALLRNAGLKYICKTVALKVE
EEECCCCHHHHHHHHHCCCCEEEEEECCEEEEHHCCCCCHHHHHHCCHHHEEHHHEEEEE
TSASAFTEGYTAGDTISIPIAHHDGNYFADDETIARLQGEDRVAFTYEDTPNGAKADIAG
CCCHHHHCCCCCCCEEEEEEEECCCCEEECCHHHEEECCCCEEEEEECCCCCCCHHHHHH
ILSSNRRVLGMMPHPERAADAGHGGTDGQALFRALTGALAAV
HHCCCCEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHAAVVVFPGSNCDRDLAVAFEAAGAQVTKVWHKDTDLPEGVDIIGIPGGFSFGDYLRCG
CCEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHC
AIAANSPICRSVAAHAERGGYVIGICNGFQVLTETGLLPGALLRNAGLKYICKTVALKVE
EEECCCCHHHHHHHHHCCCCEEEEEECCEEEEHHCCCCCHHHHHHCCHHHEEHHHEEEEE
TSASAFTEGYTAGDTISIPIAHHDGNYFADDETIARLQGEDRVAFTYEDTPNGAKADIAG
CCCHHHHCCCCCCCEEEEEEEECCCCEEECCHHHEEECCCCEEEEEECCCCCCCHHHHHH
ILSSNRRVLGMMPHPERAADAGHGGTDGQALFRALTGALAAV
HHCCCCEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA