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The map label for this gene is mtnP [H]

Identifier: 110679424

GI number: 110679424

Start: 2046350

End: 2047222

Strand: Reverse

Name: mtnP [H]

Synonym: RD1_2150

Alternate gene names: 110679424

Gene position: 2047222-2046350 (Counterclockwise)

Preceding gene: 110679426

Following gene: 110679423

Centisome position: 49.53

GC content: 61.4

Gene sequence:

>873_bases
ATGACCCAAACAAAAATAGCCGTGATCGGTGGATCCGGTCTTTATGATATAGAGGGTATGACCGGAGCGAAATGGACACA
GGTGTCAACACCATGGGGCGCACCATCCGATGATATTCTGACCGGGGAACTTGATGGTGTTCCGATGGCCTTTTTACCAC
GCCACGGACGCGGCCATGTGCATAGCCCCACCACAGTGCCCTACCGCGCAAATATCGACGCGCTCAAGCGGCTTGGGGTG
ACAGATGTCATTTCGGTGTCGGCCTGCGGTTCCTTTCGCGAGGAAATGGCACCGGGTGATTTCGTCATCGTGGATCAGTT
CATCGACCGCACCTTCGCGCGGGAAAAATCGTTCTTCGGCACAGGCTGCGTGGCACATGTCAGCGTCGCCCATCCGACCT
GCCCCCGTCTGTCCAAAGCCTGCCACACGGCGGCCACCGATGCGGGCATCACGGTGCATGACGGTGGGACTTATCTGGCG
ATGGAAGGCCCGCAGTTTTCGACCCTTGCGGAATCCAAGATGTACCGCACAAGCTGGGGCGCGGATGTGATCGGCATGAC
CAACATGCCCGAAGCGAAACTCGCCCGCGAAGCCGAACTGTGTTACGCCTCGGTCGCGATGATCACCGATTACGACAGCT
GGCACCCCGACCACGGCGAAGTCGATGTCACGCAGATCATCCAGACCCTGATGGGCAACGCGGATAAGGGCCGCGATCTG
GTGCGCCGCCTGCCGGCGATGCTCGGGCCGGAGCGCGCACCCTGCCCCCACGGCTGCGATCGCGCGCTGGATTTCGCGAT
CCTGACGCAACCCGACGCACGCGATCCGGCGGTCATGGCCAAGCTGGATGCCGTGGCCGGGCGCGTACTCTAA

Upstream 100 bases:

>100_bases
CGCGCCCTTCACAACACCTTAATGAAACCGGGCGATTTGTGCCTTTTCAACCTGCGCTTCAACGGGCAAACTGCCGGCAA
CGCACGAAAGGACAGCTTCA

Downstream 100 bases:

>100_bases
TCCAAGGAATCCATGAAATGCCTCTCGACCTCTGGCTGACCTTTGTTGCAGCCTCCACCGCGCTCCTGCTGATCCCTGGC
CCGACTGTGCTTTTGGTGCT

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTQTKIAVIGGSGLYDIEGMTGAKWTQVSTPWGAPSDDILTGELDGVPMAFLPRHGRGHVHSPTTVPYRANIDALKRLGV
TDVISVSACGSFREEMAPGDFVIVDQFIDRTFAREKSFFGTGCVAHVSVAHPTCPRLSKACHTAATDAGITVHDGGTYLA
MEGPQFSTLAESKMYRTSWGADVIGMTNMPEAKLAREAELCYASVAMITDYDSWHPDHGEVDVTQIIQTLMGNADKGRDL
VRRLPAMLGPERAPCPHGCDRALDFAILTQPDARDPAVMAKLDAVAGRVL

Sequences:

>Translated_290_residues
MTQTKIAVIGGSGLYDIEGMTGAKWTQVSTPWGAPSDDILTGELDGVPMAFLPRHGRGHVHSPTTVPYRANIDALKRLGV
TDVISVSACGSFREEMAPGDFVIVDQFIDRTFAREKSFFGTGCVAHVSVAHPTCPRLSKACHTAATDAGITVHDGGTYLA
MEGPQFSTLAESKMYRTSWGADVIGMTNMPEAKLAREAELCYASVAMITDYDSWHPDHGEVDVTQIIQTLMGNADKGRDL
VRRLPAMLGPERAPCPHGCDRALDFAILTQPDARDPAVMAKLDAVAGRVL
>Mature_289_residues
TQTKIAVIGGSGLYDIEGMTGAKWTQVSTPWGAPSDDILTGELDGVPMAFLPRHGRGHVHSPTTVPYRANIDALKRLGVT
DVISVSACGSFREEMAPGDFVIVDQFIDRTFAREKSFFGTGCVAHVSVAHPTCPRLSKACHTAATDAGITVHDGGTYLAM
EGPQFSTLAESKMYRTSWGADVIGMTNMPEAKLAREAELCYASVAMITDYDSWHPDHGEVDVTQIIQTLMGNADKGRDLV
RRLPAMLGPERAPCPHGCDRALDFAILTQPDARDPAVMAKLDAVAGRVL

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=273, Percent_Identity=44.6886446886447, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71980569, Length=243, Percent_Identity=38.6831275720165, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323045, Length=303, Percent_Identity=36.3036303630363, Blast_Score=165, Evalue=8e-42,
Organism=Drosophila melanogaster, GI20130079, Length=243, Percent_Identity=41.9753086419753, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI221459247, Length=244, Percent_Identity=34.8360655737705, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31160; Mature: 31029

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTKIAVIGGSGLYDIEGMTGAKWTQVSTPWGAPSDDILTGELDGVPMAFLPRHGRGHV
CCCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCCCEEECCCCCCCEEEECCCCCCCC
HSPTTVPYRANIDALKRLGVTDVISVSACGSFREEMAPGDFVIVDQFIDRTFAREKSFFG
CCCCCCCEECCHHHHHHCCCHHHEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCC
TGCVAHVSVAHPTCPRLSKACHTAATDAGITVHDGGTYLAMEGPQFSTLAESKMYRTSWG
CCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCC
ADVIGMTNMPEAKLAREAELCYASVAMITDYDSWHPDHGEVDVTQIIQTLMGNADKGRDL
CCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
VRRLPAMLGPERAPCPHGCDRALDFAILTQPDARDPAVMAKLDAVAGRVL
HHHHHHHHCCCCCCCCCCCHHHHEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTKIAVIGGSGLYDIEGMTGAKWTQVSTPWGAPSDDILTGELDGVPMAFLPRHGRGHV
CCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCCCEEECCCCCCCEEEECCCCCCCC
HSPTTVPYRANIDALKRLGVTDVISVSACGSFREEMAPGDFVIVDQFIDRTFAREKSFFG
CCCCCCCEECCHHHHHHCCCHHHEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCC
TGCVAHVSVAHPTCPRLSKACHTAATDAGITVHDGGTYLAMEGPQFSTLAESKMYRTSWG
CCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHCCC
ADVIGMTNMPEAKLAREAELCYASVAMITDYDSWHPDHGEVDVTQIIQTLMGNADKGRDL
CCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
VRRLPAMLGPERAPCPHGCDRALDFAILTQPDARDPAVMAKLDAVAGRVL
HHHHHHHHCCCCCCCCCCCHHHHEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA