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The map label for this gene is ctaB

Identifier: 110679411

GI number: 110679411

Start: 2035664

End: 2036608

Strand: Direct

Name: ctaB

Synonym: RD1_2136

Alternate gene names: 110679411

Gene position: 2035664-2036608 (Clockwise)

Preceding gene: 110679410

Following gene: 110679412

Centisome position: 49.25

GC content: 60.95

Gene sequence:

>945_bases
ATGGCTGACGTAGGATATACATCTTCCCCGGCGGCGAAGGAATATGAAGCGCAGCTTGGCGACTATTTCGCGTTGCTCAA
GCCGCGCGTCATGTCGCTGGTGGTCTTCACTGCGCTTGTCGGCTTGCAGGCCGCGCCTGTGTCTGTGCACCCTGTCATCG
GCTTTGCATCAATCCTGTTTGTGGCCATCGGTGCAGGGGCGTCCGGCGCGCTGAATATGTGGTGGGATGCGGATATTGAC
GCTGTGATGCGCCGCACGGCCAACCGCCCGATCCCTGCTGGCCGCGTCCAGCCGGGCGAAGCGCTGAACCTTGGCGCTGC
CTTGTCGGGCCTTTCGATCATGATGCTGGCGCTGACGGCCAATTTTCTGGCGGCGGGGCTGCTGGCCTTCACGATATTCT
TTTACGCGGTGATCTATTCCATGTGGCTGAAACGCTGGACACCTCAGAACATAGTGATCGGTGGTGCCGCGGGGGCCTTT
CCGCCGGTCATCGGCTGGGTCATCGCCACGGGGAGCCTGTCGATTGAGGCGTGGTTGATGTTTGCGCTGATCTTCATGTG
GACGCCGCCGCATTTCTGGGCGCTGGCGCTGTTCATGAAGTCTGATTACGACGACGCCGGTGTCCCGATGCTGACGGTGA
CCCATGGGCGCAAGAAAACCCGCGCGCATATCATCGCCTATACCGTGCTGCTTGCCGTGCTTGCGGTCGGGACGGGCTTC
AGCGCGATCGGCGGGCCGGTCTATCTTGCGGCGGCGCTGGTTCTGAATGCACTGTTCCTCAAGGGCGCAATCGACATCTG
GCGGCGCGATGAAGACACTGCCATCGCGGATGAATACCGGGTTGAGAAAAAGTTCTTCCGGCTGTCGCTGTGGTACTTGT
TCGCGCATTTCGGGGCCATCCTGCTGGAATCGGCGCTGCGCCCCTTTGGTTTGGGAGGCTGGTAA

Upstream 100 bases:

>100_bases
GCCGGTATCCCACGCGACCGGGTCCTGGCGTCCAACTGATGCACGTGGGGTGGGGTTCGCAGATGCTTCCCTTTGGCTTT
GGAGACCGTGAGGCGCGCAA

Downstream 100 bases:

>100_bases
AACATGGCCATTCGCGCTGAACATGAAATCCATTCGCGCCGCAAAGGGCGCAATGTGGGCGTCGGCCTGATGCTGGCCGG
ATTTGTCGTGCTTGTTCTGG

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MADVGYTSSPAAKEYEAQLGDYFALLKPRVMSLVVFTALVGLQAAPVSVHPVIGFASILFVAIGAGASGALNMWWDADID
AVMRRTANRPIPAGRVQPGEALNLGAALSGLSIMMLALTANFLAAGLLAFTIFFYAVIYSMWLKRWTPQNIVIGGAAGAF
PPVIGWVIATGSLSIEAWLMFALIFMWTPPHFWALALFMKSDYDDAGVPMLTVTHGRKKTRAHIIAYTVLLAVLAVGTGF
SAIGGPVYLAAALVLNALFLKGAIDIWRRDEDTAIADEYRVEKKFFRLSLWYLFAHFGAILLESALRPFGLGGW

Sequences:

>Translated_314_residues
MADVGYTSSPAAKEYEAQLGDYFALLKPRVMSLVVFTALVGLQAAPVSVHPVIGFASILFVAIGAGASGALNMWWDADID
AVMRRTANRPIPAGRVQPGEALNLGAALSGLSIMMLALTANFLAAGLLAFTIFFYAVIYSMWLKRWTPQNIVIGGAAGAF
PPVIGWVIATGSLSIEAWLMFALIFMWTPPHFWALALFMKSDYDDAGVPMLTVTHGRKKTRAHIIAYTVLLAVLAVGTGF
SAIGGPVYLAAALVLNALFLKGAIDIWRRDEDTAIADEYRVEKKFFRLSLWYLFAHFGAILLESALRPFGLGGW
>Mature_313_residues
ADVGYTSSPAAKEYEAQLGDYFALLKPRVMSLVVFTALVGLQAAPVSVHPVIGFASILFVAIGAGASGALNMWWDADIDA
VMRRTANRPIPAGRVQPGEALNLGAALSGLSIMMLALTANFLAAGLLAFTIFFYAVIYSMWLKRWTPQNIVIGGAAGAFP
PVIGWVIATGSLSIEAWLMFALIFMWTPPHFWALALFMKSDYDDAGVPMLTVTHGRKKTRAHIIAYTVLLAVLAVGTGFS
AIGGPVYLAAALVLNALFLKGAIDIWRRDEDTAIADEYRVEKKFFRLSLWYLFAHFGAILLESALRPFGLGGW

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=223, Percent_Identity=32.7354260089686, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786631, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71998235, Length=205, Percent_Identity=35.609756097561, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325085, Length=238, Percent_Identity=28.1512605042017, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19921064, Length=275, Percent_Identity=29.0909090909091, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_ROSDO (Q167W1)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682418.1
- STRING:   Q167W1
- GeneID:   4196601
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2136
- NMPDR:   fig|375451.6.peg.1992
- eggNOG:   COG0109
- HOGENOM:   HBG656003
- OMA:   VAVYYEL
- PhylomeDB:   Q167W1
- ProtClustDB:   PRK04375
- BioCyc:   RDEN375451:RD1_2136-MONOMER
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 33965; Mature: 33834

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91f9ed4)-; HASH(0x1cab6a5c)-; HASH(0x1cab504c)-; HASH(0x1cab620c)-; HASH(0x1cab76c0)-; HASH(0x1cab6c60)-; HASH(0x1cab3dc0)-; HASH(0x1cab4754)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVGYTSSPAAKEYEAQLGDYFALLKPRVMSLVVFTALVGLQAAPVSVHPVIGFASILF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VAIGAGASGALNMWWDADIDAVMRRTANRPIPAGRVQPGEALNLGAALSGLSIMMLALTA
HHHCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NFLAAGLLAFTIFFYAVIYSMWLKRWTPQNIVIGGAAGAFPPVIGWVIATGSLSIEAWLM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHH
FALIFMWTPPHFWALALFMKSDYDDAGVPMLTVTHGRKKTRAHIIAYTVLLAVLAVGTGF
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
SAIGGPVYLAAALVLNALFLKGAIDIWRRDEDTAIADEYRVEKKFFRLSLWYLFAHFGAI
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLESALRPFGLGGW
HHHHHHCCCCCCCH
>Mature Secondary Structure 
ADVGYTSSPAAKEYEAQLGDYFALLKPRVMSLVVFTALVGLQAAPVSVHPVIGFASILF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VAIGAGASGALNMWWDADIDAVMRRTANRPIPAGRVQPGEALNLGAALSGLSIMMLALTA
HHHCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NFLAAGLLAFTIFFYAVIYSMWLKRWTPQNIVIGGAAGAFPPVIGWVIATGSLSIEAWLM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHH
FALIFMWTPPHFWALALFMKSDYDDAGVPMLTVTHGRKKTRAHIIAYTVLLAVLAVGTGF
HHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
SAIGGPVYLAAALVLNALFLKGAIDIWRRDEDTAIADEYRVEKKFFRLSLWYLFAHFGAI
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLESALRPFGLGGW
HHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA