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The map label for this gene is xerC [H]

Identifier: 110679359

GI number: 110679359

Start: 1985421

End: 1986341

Strand: Reverse

Name: xerC [H]

Synonym: RD1_2078

Alternate gene names: 110679359

Gene position: 1986341-1985421 (Counterclockwise)

Preceding gene: 110679360

Following gene: 110679358

Centisome position: 48.06

GC content: 64.6

Gene sequence:

>921_bases
GTGAGCTTTATCAGCCCTGCCGCCGCTGATGCGCTGCAAAGCTGGCTGGCGCATCAACGCGCGATCAAGGGTGCCGCGGA
GAACACACTGATCGCCTATCAGGGCGATGTGATCGACTTTCTGTCCTTCATCACCGCGCATAAGGGCGCGCCGCAAGGTT
TGGGCGCGCTGGCGGATGTATCCGTAACCGACATGCGGGCGTGGATGGCGCAGACGCGCGAAACTGGCGTCGCGGCGCGC
TCGCTGGCGCGAAAACTCTCGGCGGTGAAGGCGTTTTACAAGTGGCTGGCCCTGCGCGAGGGCTTTGAACCCACGGCGGT
TTTATCCACGCGCGCACCCAAGTTTCAAAAGAAACTGCCCCGCCCGCTGGCCCCGGATGCGGCGCGAAACCTGATCGACG
CCATCGAAATCCAATCGCAACACCCTTGGGTCTGCGCGCGCGATGTGGCGGTCGTGACCCTGTTGTGGGGCTGCGGGTTG
CGTATTTCCGAAGCGCTCTCGCTCACCGCAGCCGACGCGCCACTGCCCGCCACACTGCGGATATCGGGCAAGGGTGGCAA
GGAACGCATCGTGCCCGTATTACCCGCCGCGCGCGACGCGGTGGACGCATATGTCAGGATGTGCCCTCACCCGCAGACCG
CTGATGCCCCGCTGTTTCGGGCGGTGCGCGGCGGGCCCTTGCGCCCCGGTGCGATCCAAAAGGTCATGGCCGCCGCGCGC
ATGCAACTGGGTTTGCCCGCCACCGCGACACCGCATGCGATGCGCCACTCCTTTGCAACCCACCTTCTGAACGCGGGCGG
TGATCTGCGCGCCATTCAGGAACTGTTGGGCCATGCCTCCCTGTCCACAACGCAAGCCTATACGGCCGTTGATACCGTGC
GTCTGATGGAGGTTTATGACCGCACCCACCCCAAAGCGTGA

Upstream 100 bases:

>100_bases
TGGGCTCACAGGACGCCGAGATGTTTGGACCCCAGCAAGGCACGGATTTACTTGTGTTTTTCACCGGCGTGCTGGAACGG
ACCCTGCGCCGCTGGGTGAC

Downstream 100 bases:

>100_bases
TCTCTTTGCAATGGATCCCCGCGAAGGCGACATTTCTTTTGCATCCCAAGGCCGTATCGGTCAAAAAGCCCGCATGACCA
ATCGAATGGCCGCGCTTGCG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSFISPAAADALQSWLAHQRAIKGAAENTLIAYQGDVIDFLSFITAHKGAPQGLGALADVSVTDMRAWMAQTRETGVAAR
SLARKLSAVKAFYKWLALREGFEPTAVLSTRAPKFQKKLPRPLAPDAARNLIDAIEIQSQHPWVCARDVAVVTLLWGCGL
RISEALSLTAADAPLPATLRISGKGGKERIVPVLPAARDAVDAYVRMCPHPQTADAPLFRAVRGGPLRPGAIQKVMAAAR
MQLGLPATATPHAMRHSFATHLLNAGGDLRAIQELLGHASLSTTQAYTAVDTVRLMEVYDRTHPKA

Sequences:

>Translated_306_residues
MSFISPAAADALQSWLAHQRAIKGAAENTLIAYQGDVIDFLSFITAHKGAPQGLGALADVSVTDMRAWMAQTRETGVAAR
SLARKLSAVKAFYKWLALREGFEPTAVLSTRAPKFQKKLPRPLAPDAARNLIDAIEIQSQHPWVCARDVAVVTLLWGCGL
RISEALSLTAADAPLPATLRISGKGGKERIVPVLPAARDAVDAYVRMCPHPQTADAPLFRAVRGGPLRPGAIQKVMAAAR
MQLGLPATATPHAMRHSFATHLLNAGGDLRAIQELLGHASLSTTQAYTAVDTVRLMEVYDRTHPKA
>Mature_305_residues
SFISPAAADALQSWLAHQRAIKGAAENTLIAYQGDVIDFLSFITAHKGAPQGLGALADVSVTDMRAWMAQTRETGVAARS
LARKLSAVKAFYKWLALREGFEPTAVLSTRAPKFQKKLPRPLAPDAARNLIDAIEIQSQHPWVCARDVAVVTLLWGCGLR
ISEALSLTAADAPLPATLRISGKGGKERIVPVLPAARDAVDAYVRMCPHPQTADAPLFRAVRGGPLRPGAIQKVMAAARM
QLGLPATATPHAMRHSFATHLLNAGGDLRAIQELLGHASLSTTQAYTAVDTVRLMEVYDRTHPKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=279, Percent_Identity=34.4086021505376, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=35.4948805460751, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790768, Length=187, Percent_Identity=28.3422459893048, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32814; Mature: 32683

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFISPAAADALQSWLAHQRAIKGAAENTLIAYQGDVIDFLSFITAHKGAPQGLGALADV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHCC
SVTDMRAWMAQTRETGVAARSLARKLSAVKAFYKWLALREGFEPTAVLSTRAPKFQKKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHCC
RPLAPDAARNLIDAIEIQSQHPWVCARDVAVVTLLWGCGLRISEALSLTAADAPLPATLR
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
ISGKGGKERIVPVLPAARDAVDAYVRMCPHPQTADAPLFRAVRGGPLRPGAIQKVMAAAR
ECCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
MQLGLPATATPHAMRHSFATHLLNAGGDLRAIQELLGHASLSTTQAYTAVDTVRLMEVYD
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RTHPKA
HCCCCC
>Mature Secondary Structure 
SFISPAAADALQSWLAHQRAIKGAAENTLIAYQGDVIDFLSFITAHKGAPQGLGALADV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHCC
SVTDMRAWMAQTRETGVAARSLARKLSAVKAFYKWLALREGFEPTAVLSTRAPKFQKKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHCC
RPLAPDAARNLIDAIEIQSQHPWVCARDVAVVTLLWGCGLRISEALSLTAADAPLPATLR
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
ISGKGGKERIVPVLPAARDAVDAYVRMCPHPQTADAPLFRAVRGGPLRPGAIQKVMAAAR
ECCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
MQLGLPATATPHAMRHSFATHLLNAGGDLRAIQELLGHASLSTTQAYTAVDTVRLMEVYD
HHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
RTHPKA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]