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The map label for this gene is yngJ [H]

Identifier: 110679346

GI number: 110679346

Start: 1972370

End: 1973605

Strand: Direct

Name: yngJ [H]

Synonym: RD1_2065

Alternate gene names: 110679346

Gene position: 1972370-1973605 (Clockwise)

Preceding gene: 110679341

Following gene: 110679347

Centisome position: 47.72

GC content: 60.6

Gene sequence:

>1236_bases
ATGGATATGAATTTCGGCATGCGAGAAGAGAACCGCGCGTTGTTGCAGCGTGTCGCCGATATGATCCGGGACGTCGTCAT
GCCGCTGGAAGAAGAATACCACGGCGAAATCGGTCAGGGGGACCGCTGGCACTATACCGACCGGCAGGCGGAAATCCTCG
AAGGGCTCAAGGCGCAGGCGAAAGCGGCCGGGTTGTGGAATTTCTGGCTGACCGACAGTGACAAGGGGTTCGGCCTCAGC
ACCGTGGAATACGCGTATTTTGCCGAAGAGATGGGAAAGACCCCCCTCGGGGCGGAGGTGTTCAACTGCTCGGCACCTGA
CACGGGCAACATGGAAGTCTTTGAACGCTACGGCACGCCCGCGATGAAGGAACAATGGCTCGCGCCACTGCTGGAGGGGG
AGATTCGCTCTGCCTATCTGATGACGGAACCGGAAGTGGCCTCGTCTGATGCGACCAATATCGCCATGTCCTGCGTGCGG
GATGGGGACGATTATGTGCTCAATGGCGAAAAATACTGGGCCAGCGGTGCCGGTGATCCGCGCTGCAAGGTCTACATCGT
CATGGTGCGCACGGGCGGTGACGAGGTCTCAAAACACCAGCGCCATTCGATGATTGTCGTGGATGCGGCGACACCGGGGA
TCGAAATCCTGCGCCCGATGAAGGTATTTGGCCATGATGATGCGCCGCATGGGCATATGCATATCCGTTTTTCGGATGTG
CGCGTGCCTGCCGAAAACCTGTTGCTGGGTGAGGGGCGCGGTTTTGAGATCGCGCAGGGGCGTCTGGGGCCGGGGCGTAT
TCATCACTGCATGCGCTCGGTCGGGCAGGCCGAAGCGGCGCTGGAGTTGATGTGCAAAAGGTCCCTGCAAAAGGAAGCCT
TCGGCAAACCGCTGGCGATGCTGGGGGCGAATTTCGACATCATCGCGGAATGTCGGATGGAAATCGAGATGGCCCGTCTG
TTGTGCCTCAAGGCGGCGTGGATGATGGATCAGGGAGACGCGCGCGCGGCCGCCCCGTGGATCAGCCAGATCAAGGTCGT
GGCCCCGCGCATGGCCCTCAAGGTGATTGATGAGGCGATGCAGATGCATGGTGGGCAGGGCATAAGTCAGGACACGCCGC
TGGCCATGGCCTGGACATGGCAGCGCGCTCTGCGCTTTGCCGATGGCCCGGATGCGGTGCACCGCCGTCAGGTTGCGCGC
ACGGAATTGCGCAAACACACGCAGCAAAAAATCTGA

Upstream 100 bases:

>100_bases
ATGCGCATCCCCCTTGATTTGTCTTATGGACACCGCAGGTGATCTAAGCAAACCTGTGCCGCGGGGGAAAGCCCCGTTGG
GCGGGCTGAAGGAGACGGTG

Downstream 100 bases:

>100_bases
GACATTTGGTTGTCCATGCCATGCAGGGCGCGGGGCGGCGAATATGGCGAAATATCGTAAAATGTATATAATTCTGTATT
CTGGAAGTGTTCGTTGGTCA

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDMNFGMREENRALLQRVADMIRDVVMPLEEEYHGEIGQGDRWHYTDRQAEILEGLKAQAKAAGLWNFWLTDSDKGFGLS
TVEYAYFAEEMGKTPLGAEVFNCSAPDTGNMEVFERYGTPAMKEQWLAPLLEGEIRSAYLMTEPEVASSDATNIAMSCVR
DGDDYVLNGEKYWASGAGDPRCKVYIVMVRTGGDEVSKHQRHSMIVVDAATPGIEILRPMKVFGHDDAPHGHMHIRFSDV
RVPAENLLLGEGRGFEIAQGRLGPGRIHHCMRSVGQAEAALELMCKRSLQKEAFGKPLAMLGANFDIIAECRMEIEMARL
LCLKAAWMMDQGDARAAAPWISQIKVVAPRMALKVIDEAMQMHGGQGISQDTPLAMAWTWQRALRFADGPDAVHRRQVAR
TELRKHTQQKI

Sequences:

>Translated_411_residues
MDMNFGMREENRALLQRVADMIRDVVMPLEEEYHGEIGQGDRWHYTDRQAEILEGLKAQAKAAGLWNFWLTDSDKGFGLS
TVEYAYFAEEMGKTPLGAEVFNCSAPDTGNMEVFERYGTPAMKEQWLAPLLEGEIRSAYLMTEPEVASSDATNIAMSCVR
DGDDYVLNGEKYWASGAGDPRCKVYIVMVRTGGDEVSKHQRHSMIVVDAATPGIEILRPMKVFGHDDAPHGHMHIRFSDV
RVPAENLLLGEGRGFEIAQGRLGPGRIHHCMRSVGQAEAALELMCKRSLQKEAFGKPLAMLGANFDIIAECRMEIEMARL
LCLKAAWMMDQGDARAAAPWISQIKVVAPRMALKVIDEAMQMHGGQGISQDTPLAMAWTWQRALRFADGPDAVHRRQVAR
TELRKHTQQKI
>Mature_411_residues
MDMNFGMREENRALLQRVADMIRDVVMPLEEEYHGEIGQGDRWHYTDRQAEILEGLKAQAKAAGLWNFWLTDSDKGFGLS
TVEYAYFAEEMGKTPLGAEVFNCSAPDTGNMEVFERYGTPAMKEQWLAPLLEGEIRSAYLMTEPEVASSDATNIAMSCVR
DGDDYVLNGEKYWASGAGDPRCKVYIVMVRTGGDEVSKHQRHSMIVVDAATPGIEILRPMKVFGHDDAPHGHMHIRFSDV
RVPAENLLLGEGRGFEIAQGRLGPGRIHHCMRSVGQAEAALELMCKRSLQKEAFGKPLAMLGANFDIIAECRMEIEMARL
LCLKAAWMMDQGDARAAAPWISQIKVVAPRMALKVIDEAMQMHGGQGISQDTPLAMAWTWQRALRFADGPDAVHRRQVAR
TELRKHTQQKI

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=410, Percent_Identity=49.7560975609756, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=51.7587939698493, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=51.7587939698493, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI4557231, Length=407, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI187960098, Length=407, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI7656849, Length=293, Percent_Identity=30.7167235494881, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4557233, Length=404, Percent_Identity=25, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4501859, Length=358, Percent_Identity=25.4189944134078, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI76496475, Length=350, Percent_Identity=28, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4557235, Length=350, Percent_Identity=28, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=23.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958412, Length=397, Percent_Identity=23.1738035264484, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958414, Length=325, Percent_Identity=23.6923076923077, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501857, Length=312, Percent_Identity=26.2820512820513, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI87081958, Length=323, Percent_Identity=26.0061919504644, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786223, Length=299, Percent_Identity=24.4147157190635, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562446, Length=405, Percent_Identity=46.1728395061728, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17534899, Length=411, Percent_Identity=25.7907542579075, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=416, Percent_Identity=25.4807692307692, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=409, Percent_Identity=24.9388753056235, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=27.5482093663912, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=361, Percent_Identity=26.8698060941828, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=397, Percent_Identity=22.4181360201511, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=336, Percent_Identity=22.9166666666667, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=260, Percent_Identity=26.1538461538462, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=326, Percent_Identity=23.3128834355828, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=26.3888888888889, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=291, Percent_Identity=25.4295532646048, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=21.8137254901961, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=300, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24660351, Length=409, Percent_Identity=27.3838630806846, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=27.9683377308707, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646207, Length=342, Percent_Identity=27.4853801169591, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24666513, Length=263, Percent_Identity=30.0380228136882, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=26.9230769230769, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355753, Length=325, Percent_Identity=24.9230769230769, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45967; Mature: 45967

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNFGMREENRALLQRVADMIRDVVMPLEEEYHGEIGQGDRWHYTDRQAEILEGLKAQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
KAAGLWNFWLTDSDKGFGLSTVEYAYFAEEMGKTPLGAEVFNCSAPDTGNMEVFERYGTP
HHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCC
AMKEQWLAPLLEGEIRSAYLMTEPEVASSDATNIAMSCVRDGDDYVLNGEKYWASGAGDP
HHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCEEEECCCCCC
RCKVYIVMVRTGGDEVSKHQRHSMIVVDAATPGIEILRPMKVFGHDDAPHGHMHIRFSDV
CEEEEEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECE
RVPAENLLLGEGRGFEIAQGRLGPGRIHHCMRSVGQAEAALELMCKRSLQKEAFGKPLAM
ECCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGANFDIIAECRMEIEMARLLCLKAAWMMDQGDARAAAPWISQIKVVAPRMALKVIDEAM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMHGGQGISQDTPLAMAWTWQRALRFADGPDAVHRRQVARTELRKHTQQKI
HHCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDMNFGMREENRALLQRVADMIRDVVMPLEEEYHGEIGQGDRWHYTDRQAEILEGLKAQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
KAAGLWNFWLTDSDKGFGLSTVEYAYFAEEMGKTPLGAEVFNCSAPDTGNMEVFERYGTP
HHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHCCCC
AMKEQWLAPLLEGEIRSAYLMTEPEVASSDATNIAMSCVRDGDDYVLNGEKYWASGAGDP
HHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCEEEECCCCCC
RCKVYIVMVRTGGDEVSKHQRHSMIVVDAATPGIEILRPMKVFGHDDAPHGHMHIRFSDV
CEEEEEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEEECE
RVPAENLLLGEGRGFEIAQGRLGPGRIHHCMRSVGQAEAALELMCKRSLQKEAFGKPLAM
ECCHHHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LGANFDIIAECRMEIEMARLLCLKAAWMMDQGDARAAAPWISQIKVVAPRMALKVIDEAM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMHGGQGISQDTPLAMAWTWQRALRFADGPDAVHRRQVARTELRKHTQQKI
HHCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]