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The map label for this gene is hda [H]

Identifier: 110679324

GI number: 110679324

Start: 1952048

End: 1952731

Strand: Reverse

Name: hda [H]

Synonym: RD1_2043

Alternate gene names: 110679324

Gene position: 1952731-1952048 (Counterclockwise)

Preceding gene: 110679325

Following gene: 110679323

Centisome position: 47.25

GC content: 63.74

Gene sequence:

>684_bases
ATGCCCGAACAGCTTGGTTTGGACCTGCCCGGCATCACCGCACTGGGGCGGGCGGATTTTCTGGTGGCGCCGTCAAATGC
TCTCGCCGTGGCCCTGATCGAGGGCTGGCAGGACTGGCCGGGGCGCAAACTTGTGCTGAGCGGCCCGGCAGGATCGGGAA
AGACGCATCTTGCACATGTGTGGGCCGCCCTCAGCGGCGCAGAGATCTGTCCGGCGCGCGACCTTGTCGGGCAGGACATT
CCCGATCTGGCACGACGTTCCGTCGCGATCGAAGACGTGCCCGACATCGCCGGGAATGCGCAGGCTGAAACGGCATTGTT
TCACCTACACAACCTTGCGTTGGCCGAGGGCAACGCACTGCTCTTTACCGGTGAGGCCGCGCCGCGTGCGTGGCATCTGA
ACCTGCCGGACCTCAAAAGCCGGATAGAGGGGACGCAGGCGGTCTCCCTTGATTTGCCCGATGACGCGCTGCTGTCGGCG
GTGCTCGCCAAGCTTTTTGCAGATCGGCAACTGACGCCGAAACCTGAGCTGATTGCCTATCTGATCCTGCGCATCGACCG
CTCGTTTGCAGCCGCGCGCAGGATCGTTGCGGCCCTTGATGCGGCATCGCTGGCGCAAAAGCGCCCGCTCTCACGGCAAC
TTGCGGCGGCAGTGCTGGACAAAGAGGATCAGCTTGCGCGATAA

Upstream 100 bases:

>100_bases
CCGCTCGCCGCGGCCCTCGGGGTTCTGGCGCGCTTTGGCGTTGCGCAATACACAAACTCGCTGCTTTATCGTGGCATGTC
GGACAAGGATCAGGACTGAC

Downstream 100 bases:

>100_bases
ATGTCATTCAGCCGACACATGCTTTTTGCAAAAGGTCAAAATGACACAAGCAGATTTTCTCAGCGCAGATTTTCCAGAAC
CGGTGGCGCTTCCCAATGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPEQLGLDLPGITALGRADFLVAPSNALAVALIEGWQDWPGRKLVLSGPAGSGKTHLAHVWAALSGAEICPARDLVGQDI
PDLARRSVAIEDVPDIAGNAQAETALFHLHNLALAEGNALLFTGEAAPRAWHLNLPDLKSRIEGTQAVSLDLPDDALLSA
VLAKLFADRQLTPKPELIAYLILRIDRSFAAARRIVAALDAASLAQKRPLSRQLAAAVLDKEDQLAR

Sequences:

>Translated_227_residues
MPEQLGLDLPGITALGRADFLVAPSNALAVALIEGWQDWPGRKLVLSGPAGSGKTHLAHVWAALSGAEICPARDLVGQDI
PDLARRSVAIEDVPDIAGNAQAETALFHLHNLALAEGNALLFTGEAAPRAWHLNLPDLKSRIEGTQAVSLDLPDDALLSA
VLAKLFADRQLTPKPELIAYLILRIDRSFAAARRIVAALDAASLAQKRPLSRQLAAAVLDKEDQLAR
>Mature_226_residues
PEQLGLDLPGITALGRADFLVAPSNALAVALIEGWQDWPGRKLVLSGPAGSGKTHLAHVWAALSGAEICPARDLVGQDIP
DLARRSVAIEDVPDIAGNAQAETALFHLHNLALAEGNALLFTGEAAPRAWHLNLPDLKSRIEGTQAVSLDLPDDALLSAV
LAKLFADRQLTPKPELIAYLILRIDRSFAAARRIVAALDAASLAQKRPLSRQLAAAVLDKEDQLAR

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=187, Percent_Identity=31.5508021390374, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 24137; Mature: 24006

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQLGLDLPGITALGRADFLVAPSNALAVALIEGWQDWPGRKLVLSGPAGSGKTHLAHV
CCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHH
WAALSGAEICPARDLVGQDIPDLARRSVAIEDVPDIAGNAQAETALFHLHNLALAEGNAL
HHHHCCCCCCCHHHHHCCCCHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHEECCCEE
LFTGEAAPRAWHLNLPDLKSRIEGTQAVSLDLPDDALLSAVLAKLFADRQLTPKPELIAY
EEECCCCCCEEECCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHH
LILRIDRSFAAARRIVAALDAASLAQKRPLSRQLAAAVLDKEDQLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
PEQLGLDLPGITALGRADFLVAPSNALAVALIEGWQDWPGRKLVLSGPAGSGKTHLAHV
CCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHH
WAALSGAEICPARDLVGQDIPDLARRSVAIEDVPDIAGNAQAETALFHLHNLALAEGNAL
HHHHCCCCCCCHHHHHCCCCHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHEECCCEE
LFTGEAAPRAWHLNLPDLKSRIEGTQAVSLDLPDDALLSAVLAKLFADRQLTPKPELIAY
EEECCCCCCEEECCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHH
LILRIDRSFAAARRIVAALDAASLAQKRPLSRQLAAAVLDKEDQLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA