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The map label for this gene is yciL [C]

Identifier: 110679275

GI number: 110679275

Start: 1903112

End: 1903969

Strand: Reverse

Name: yciL [C]

Synonym: RD1_1992

Alternate gene names: 110679275

Gene position: 1903969-1903112 (Counterclockwise)

Preceding gene: 110679277

Following gene: 110679274

Centisome position: 46.07

GC content: 63.05

Gene sequence:

>858_bases
ATGACCTCTGAACTCACGCCACAGGGCGACCGCATTGCCAAAGTCCTCAGCCGCGCCGGTGTCGCCAGCCGCCGCGAGGC
GGAACGCATGATCGAAGCCGGCCGCGTCAAGGTTAATGGCAAGCCCATTTCATCCCCCGCCCTGAATGTGCAGGCCAGTG
ACAAGATCACTGTGGATGGCAAGGACGTATCCCCTCCGGAACCCGCGCGGCTTTGGCTCTATCACAAACCCACGGGCCTT
GTGACGACGGACAATGACGAAAAGGGCCGCGAAACGATCTACAGCGCCCTGCCTGCGGATTTGCCGCGTGTGATGAGCGT
CGGGCGGCTCGATATCAATTCCGAGGGGCTGTTGCTGCTGACCAATGATGGCAGTATCAAACGCCGCCTCGAACTGCCCA
CGACGGGCTGGCTGCGTCGCTACCGCGTGCGCGTCAACGGCAGGCCCACGGATGCGACACTGGAGCCGCTGCGGCGCGGG
ATCAGCAGCGAGGGCGAGAATTTTCAACCCATGCAGGTCACGCTGGACCGCCAGCAAGGCGCGAATGCGTGGCTGACAAT
GGGCCTGCGCGAGGGCAAAAACCGTGAAATTCGCCGCGCGCTGGCAGAACTGGGGCTCACTGTGAACCGCCTGATCCGGA
TCAGCTATGGGCCTTTTCAGTTGGGCGAGTTGAAATCCGGCGCTGTCGAAGAGGTCCGTCGCAAGGTTCTGCGCGATCAA
CTGGGCCTTGAAGAGGACGCAGGCACCGACCCGGCAAAACGCCTCGAGGCGGGCAGGAAGCGCGGACCACCCATCCGCCG
GACGCGCGCGACTGCTGGCGCAAAACCCGCCAGATACGCCAAAAAACCACGCAAATGA

Upstream 100 bases:

>100_bases
CAGAGAGGGCCGCTTCCATATGCGTGTTGAACTGCATGGGCCTAGTTGCACGCAAACTGTTCTCTTTCGCAAGGGCCGCA
AACAGGCTATGCCCCGCCCC

Downstream 100 bases:

>100_bases
CGCGTGCCCTGCGTCTTTCCCCCTCGAATACGGGGGAAAATGCAGCCATGTCATTACCGATGCATCCGCGATCTGTTACC
AAGGCAGGCGCGGTTGTTCA

Product: RNA pseudouridylate synthase family protein, putative

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTSELTPQGDRIAKVLSRAGVASRREAERMIEAGRVKVNGKPISSPALNVQASDKITVDGKDVSPPEPARLWLYHKPTGL
VTTDNDEKGRETIYSALPADLPRVMSVGRLDINSEGLLLLTNDGSIKRRLELPTTGWLRRYRVRVNGRPTDATLEPLRRG
ISSEGENFQPMQVTLDRQQGANAWLTMGLREGKNREIRRALAELGLTVNRLIRISYGPFQLGELKSGAVEEVRRKVLRDQ
LGLEEDAGTDPAKRLEAGRKRGPPIRRTRATAGAKPARYAKKPRK

Sequences:

>Translated_285_residues
MTSELTPQGDRIAKVLSRAGVASRREAERMIEAGRVKVNGKPISSPALNVQASDKITVDGKDVSPPEPARLWLYHKPTGL
VTTDNDEKGRETIYSALPADLPRVMSVGRLDINSEGLLLLTNDGSIKRRLELPTTGWLRRYRVRVNGRPTDATLEPLRRG
ISSEGENFQPMQVTLDRQQGANAWLTMGLREGKNREIRRALAELGLTVNRLIRISYGPFQLGELKSGAVEEVRRKVLRDQ
LGLEEDAGTDPAKRLEAGRKRGPPIRRTRATAGAKPARYAKKPRK
>Mature_284_residues
TSELTPQGDRIAKVLSRAGVASRREAERMIEAGRVKVNGKPISSPALNVQASDKITVDGKDVSPPEPARLWLYHKPTGLV
TTDNDEKGRETIYSALPADLPRVMSVGRLDINSEGLLLLTNDGSIKRRLELPTTGWLRRYRVRVNGRPTDATLEPLRRGI
SSEGENFQPMQVTLDRQQGANAWLTMGLREGKNREIRRALAELGLTVNRLIRISYGPFQLGELKSGAVEEVRRKVLRDQL
GLEEDAGTDPAKRLEAGRKRGPPIRRTRATAGAKPARYAKKPRK

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=218, Percent_Identity=41.743119266055, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI87081838, Length=181, Percent_Identity=34.8066298342541, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790453, Length=281, Percent_Identity=29.8932384341637, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788510, Length=203, Percent_Identity=25.615763546798, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 31639; Mature: 31508

Theoretical pI: Translated: 11.16; Mature: 11.16

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSELTPQGDRIAKVLSRAGVASRREAERMIEAGRVKVNGKPISSPALNVQASDKITVDG
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCEEEECCEECCCCCEEEECCCEEEECC
KDVSPPEPARLWLYHKPTGLVTTDNDEKGRETIYSALPADLPRVMSVGRLDINSEGLLLL
CCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHCCCCHHHHHHCCCEEECCCCEEEE
TNDGSIKRRLELPTTGWLRRYRVRVNGRPTDATLEPLRRGISSEGENFQPMQVTLDRQQG
ECCCCCEEEEECCCHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ANAWLTMGLREGKNREIRRALAELGLTVNRLIRISYGPFQLGELKSGAVEEVRRKVLRDQ
CCEEEEECCCCCCCHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
LGLEEDAGTDPAKRLEAGRKRGPPIRRTRATAGAKPARYAKKPRK
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TSELTPQGDRIAKVLSRAGVASRREAERMIEAGRVKVNGKPISSPALNVQASDKITVDG
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCEEEECCEECCCCCEEEECCCEEEECC
KDVSPPEPARLWLYHKPTGLVTTDNDEKGRETIYSALPADLPRVMSVGRLDINSEGLLLL
CCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHCCCCHHHHHHCCCEEECCCCEEEE
TNDGSIKRRLELPTTGWLRRYRVRVNGRPTDATLEPLRRGISSEGENFQPMQVTLDRQQG
ECCCCCEEEEECCCHHHHEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ANAWLTMGLREGKNREIRRALAELGLTVNRLIRISYGPFQLGELKSGAVEEVRRKVLRDQ
CCEEEEECCCCCCCHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
LGLEEDAGTDPAKRLEAGRKRGPPIRRTRATAGAKPARYAKKPRK
CCCCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]