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The map label for this gene is phnW [H]

Identifier: 110679244

GI number: 110679244

Start: 1869449

End: 1870576

Strand: Direct

Name: phnW [H]

Synonym: RD1_1957

Alternate gene names: 110679244

Gene position: 1869449-1870576 (Clockwise)

Preceding gene: 110679243

Following gene: 110679248

Centisome position: 45.23

GC content: 60.11

Gene sequence:

>1128_bases
ATGGCTGCCTTGCTTGACACGATTGACCCCGACGGTCTCGAAGAGTTTTCGGTTGTGTTCACCGACCGGTCGCTGAACTC
CATGAGCGCGGCATTTCAGAAGGTGATGAACGACATCTCCGGTATGCTCAAGGACGTCTACAGCGCGGATGCCGTGGTGA
TCATTCCCGGTGGCGGGACTTTCGGGATGGAAGCTGTCGCACGGCAATTCGCGCGCAATGCGGATGTTCTGGTGGTGCGC
AACGGCTGGTTTTCCTATCGCTGGAGCCAGATTTTCGAAACCGGTGGATTGACGGCCAATACGACCGTTCTCAAGGCGCG
CCAGACCGGCAATGCCAGCCCGCCCCCCTTTGCGCCGGCGCCCATCGAAGAGGTTGTCGCGGCCATTCGCGAGCAGAAAC
CGGATGTGGTTTTTGCACCGCACGTTGAGACAAGTGCGGGTGTCATTCTGCCGGATGATTATGTCACCGCGATGGCCAGC
GCCGCGCATGAGGTCGGCGCGTTGATGGTGCTTGATTGCATCGCCTCGGGTTGTGCGTGGATTGACATGCGCATAACCGG
TGTCGATGTCCTGATCTCAGCGCCGCAAAAAGGCTGGTCCGCGTCCCCGTCGGCGGGACTTGTGATGCTGTCGGAGCGTG
CCGTGGCGCGCCTGGCCGAGACGCAGTCGGACAGTTTTGCGATTGATCTGGGCAAGTGGCACAGCATCATGCAGGCCTAT
GAAAATGGCGGGCATGCCTATCACGCCACCATGCCCACGGATGCCTTGCGCGCGTTCCGTGACACGATGCTGGAAACGCG
CGAGTACGGTTTTGAGCGCCTCAAGGATGCACAATGGGACCTTGGCAACCGGGTGCGCGACATGCTTGCCGCAAAAGGGG
TCGTTTCGGTCGCGGCGGATGGGTTTGGCGCACCGGGCGTCGTGGTCAGCTATACCGCTGATCCGGATATCCAGAATGGC
AAGAAGTTCATGGCGCAGGGCATGCAGATTGCGGCGGGTGTGCCGCTTCAATGCGATGAACCGGCAGATTTCAGGACATT
CCGTCTGGGGCTCTTTGGGCTCGACAAGCTTTATGATGTCGATGGGACCGTTGCTCGCCTCGCGCGGGTGTTGGACGACG
TCATCTGA

Upstream 100 bases:

>100_bases
AGGTGCTGTGCAGGAATGTGCAGGGGTGCGGCAAAGCAGGCTTTGCCCCTGATCACCGGACGCGTTAAAGGAGAAGTCAG
GATTTTACAGGAGAATACAA

Downstream 100 bases:

>100_bases
CGCCAAGCCCCATCTGCATCAGGGTGCGCCGGACAGGGCCGAGCGCATACAGGGCATTCAATCCCATGGCACGCGCGTCT
CTGAGGGCGGGCGTGTGCAC

Product: aminotransferase family protein, putative

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAALLDTIDPDGLEEFSVVFTDRSLNSMSAAFQKVMNDISGMLKDVYSADAVVIIPGGGTFGMEAVARQFARNADVLVVR
NGWFSYRWSQIFETGGLTANTTVLKARQTGNASPPPFAPAPIEEVVAAIREQKPDVVFAPHVETSAGVILPDDYVTAMAS
AAHEVGALMVLDCIASGCAWIDMRITGVDVLISAPQKGWSASPSAGLVMLSERAVARLAETQSDSFAIDLGKWHSIMQAY
ENGGHAYHATMPTDALRAFRDTMLETREYGFERLKDAQWDLGNRVRDMLAAKGVVSVAADGFGAPGVVVSYTADPDIQNG
KKFMAQGMQIAAGVPLQCDEPADFRTFRLGLFGLDKLYDVDGTVARLARVLDDVI

Sequences:

>Translated_375_residues
MAALLDTIDPDGLEEFSVVFTDRSLNSMSAAFQKVMNDISGMLKDVYSADAVVIIPGGGTFGMEAVARQFARNADVLVVR
NGWFSYRWSQIFETGGLTANTTVLKARQTGNASPPPFAPAPIEEVVAAIREQKPDVVFAPHVETSAGVILPDDYVTAMAS
AAHEVGALMVLDCIASGCAWIDMRITGVDVLISAPQKGWSASPSAGLVMLSERAVARLAETQSDSFAIDLGKWHSIMQAY
ENGGHAYHATMPTDALRAFRDTMLETREYGFERLKDAQWDLGNRVRDMLAAKGVVSVAADGFGAPGVVVSYTADPDIQNG
KKFMAQGMQIAAGVPLQCDEPADFRTFRLGLFGLDKLYDVDGTVARLARVLDDVI
>Mature_374_residues
AALLDTIDPDGLEEFSVVFTDRSLNSMSAAFQKVMNDISGMLKDVYSADAVVIIPGGGTFGMEAVARQFARNADVLVVRN
GWFSYRWSQIFETGGLTANTTVLKARQTGNASPPPFAPAPIEEVVAAIREQKPDVVFAPHVETSAGVILPDDYVTAMASA
AHEVGALMVLDCIASGCAWIDMRITGVDVLISAPQKGWSASPSAGLVMLSERAVARLAETQSDSFAIDLGKWHSIMQAYE
NGGHAYHATMPTDALRAFRDTMLETREYGFERLKDAQWDLGNRVRDMLAAKGVVSVAADGFGAPGVVVSYTADPDIQNGK
KFMAQGMQIAAGVPLQCDEPADFRTFRLGLFGLDKLYDVDGTVARLARVLDDVI

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=254, Percent_Identity=26.3779527559055, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321079, Length=321, Percent_Identity=26.1682242990654, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 40308; Mature: 40177

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALLDTIDPDGLEEFSVVFTDRSLNSMSAAFQKVMNDISGMLKDVYSADAVVIIPGGGT
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FGMEAVARQFARNADVLVVRNGWFSYRWSQIFETGGLTANTTVLKARQTGNASPPPFAPA
CCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEECCEEEEEECCCCCCCCCCCCC
PIEEVVAAIREQKPDVVFAPHVETSAGVILPDDYVTAMASAAHEVGALMVLDCIASGCAW
CHHHHHHHHHHCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IDMRITGVDVLISAPQKGWSASPSAGLVMLSERAVARLAETQSDSFAIDLGKWHSIMQAY
EEEEEECEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
ENGGHAYHATMPTDALRAFRDTMLETREYGFERLKDAQWDLGNRVRDMLAAKGVVSVAAD
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCC
GFGAPGVVVSYTADPDIQNGKKFMAQGMQIAAGVPLQCDEPADFRTFRLGLFGLDKLYDV
CCCCCCEEEEEECCCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHCC
DGTVARLARVLDDVI
CHHHHHHHHHHHHCC
>Mature Secondary Structure 
AALLDTIDPDGLEEFSVVFTDRSLNSMSAAFQKVMNDISGMLKDVYSADAVVIIPGGGT
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
FGMEAVARQFARNADVLVVRNGWFSYRWSQIFETGGLTANTTVLKARQTGNASPPPFAPA
CCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEECCEEEEEECCCCCCCCCCCCC
PIEEVVAAIREQKPDVVFAPHVETSAGVILPDDYVTAMASAAHEVGALMVLDCIASGCAW
CHHHHHHHHHHCCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IDMRITGVDVLISAPQKGWSASPSAGLVMLSERAVARLAETQSDSFAIDLGKWHSIMQAY
EEEEEECEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
ENGGHAYHATMPTDALRAFRDTMLETREYGFERLKDAQWDLGNRVRDMLAAKGVVSVAAD
HCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCC
GFGAPGVVVSYTADPDIQNGKKFMAQGMQIAAGVPLQCDEPADFRTFRLGLFGLDKLYDV
CCCCCCEEEEEECCCCCCCCHHHHHCCCHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHCC
DGTVARLARVLDDVI
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA