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The map label for this gene is trkH-1 [H]

Identifier: 110679229

GI number: 110679229

Start: 1850634

End: 1852124

Strand: Direct

Name: trkH-1 [H]

Synonym: RD1_1942

Alternate gene names: 110679229

Gene position: 1850634-1852124 (Clockwise)

Preceding gene: 110679228

Following gene: 110679230

Centisome position: 44.78

GC content: 57.55

Gene sequence:

>1491_bases
ATGCGCTTGACACCAGCGGAGCGCCGCGCCAACCCTGCGCATATGTTGGACTTGCGCCCCGTCGGATATGTGATCGGTTT
GCTGGTGGCCGTATTGGGTGCGGCCATGGTGCTGCCGATGATGATCGACATTGCCGAAGGGCGCGCGCATTGGCCGGTTT
TTCTGCAATCCGCGCTCTTTACGGTCCTTGCGGGGGGGCTGATTGCCGTTGCCTGCTCGAACGGCGTCAAGGAAGGGCTG
ACGATCCAGCAAACGTTCATCCTGACCACCGGGGTCTGGGTCGCTCTGCCGCTTTTCGGGGCCATCCCTTTCGTGCTTGG
CGCGACCGAGGCGCGTTTTGTCGATGCGTTTTTTGAAGCGATGTCTGGCCTGACCACCACAGGCTCCACCGTGTTCACCG
GACTTGAAACGCTGCCCAAGGGGTTGCTCTTGTGGCGCGGTATTCTGCAATGGCTGGGGGGCATCGGTATCATCGTTGTC
GCCATGGTGTTCCTGCCAGAGCTGCGGGTCGGCGGTATGCAGATCTTTAAATCTGAAGCCTTTGATACCATGGGTAAAAT
CCTGCCCCGTGCGACGCAGATCGCCAGCCAGATCTCCAGTATCTACCTTGGCCTGACCATGGCCTGTGCGCTGTGCTATC
TTGCGCTCGGGCTGGATGCCTTTGATGCGACAGTCCACGCGCTGACGACGGTTTCAACCGGCGGTTTTGCCAATTACGAT
GCGTCCTTCGGCACCTTTTCCGGCCCGCCGGAATATGTGGCGAGCCTGTTCATGATCCTCGCAGCCCTGCCTTTCGTGCG
CTATGTGCAGATGATCAATGGCCACACGGAACCGCTGTGGCGCGACAGTCAGGTGCGTGTGTTCCTGATAACGCTGATGA
TCATCGTGCTCGCCATCGCCATCGCATTGACGCAGATTTTTCCCAAGGACGCCGAAACCGCATTTCGCGAAGCGCTTTTC
AATGTGACCTCGATCATGACGGGCACGGGGTATTCATCGGCGGATTACATGCAATGGGGGCCTTTGCTGATCTCGCTTTT
CTTCTTTATTGGCCTGATTGGCGGCTGTGCGGGTTCAACCACCTGTTCGATCAAGATTTTCCGCTATCAGTTGCTGTTTG
CCTCGATCCGCTTGCAACTGCGCAAAATCCGCTCGCCCAATGGTGTGTTTATCGTGCGCTATGAAAAGCGGGCCGTCGAT
GAGGAAGTCCTCAGTTCGGTGATGTCCTTTTTCATGTTCTTCGTGTTGACGCTGGGGTTGCTGGCGGTTGCGCTCAGCCT
CACGGGTCTTGATTTCATCACCTCGCTTTCGGGCGCGGCCACGGCCTTGTCCAATGTCGGGCCGGGGCTGGGCGATGAAA
TTGGCCCCGCTGGCAATTTTGCGGGTCTGAATGACACCGCCAAGTGGCTTTTGTCACTTGGCATGTTATTGGGTCGGCTC
GAACTTCTGGCCGTCTATGCCATGCTCACCCTTTCATTCTGGAGAGATTGA

Upstream 100 bases:

>100_bases
TGTGATTTGCCTTTTTGGGGCAAACTCGGCGCGAGTGTATCTCAACCGGCCGTAACGCGCGGCGGCCTCGCGGGCAGGCG
GTATTTGCAGAGCAGACCGG

Downstream 100 bases:

>100_bases
TATGCAACGTCCCCTGGGAGCGCAGATTTCACATATGCTCAAGGATCGCGGTGTCGATGTCATCTTTGGCATTCCCGGCG
TCCACAATCAGGAAATGTAT

Product: Trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MRLTPAERRANPAHMLDLRPVGYVIGLLVAVLGAAMVLPMMIDIAEGRAHWPVFLQSALFTVLAGGLIAVACSNGVKEGL
TIQQTFILTTGVWVALPLFGAIPFVLGATEARFVDAFFEAMSGLTTTGSTVFTGLETLPKGLLLWRGILQWLGGIGIIVV
AMVFLPELRVGGMQIFKSEAFDTMGKILPRATQIASQISSIYLGLTMACALCYLALGLDAFDATVHALTTVSTGGFANYD
ASFGTFSGPPEYVASLFMILAALPFVRYVQMINGHTEPLWRDSQVRVFLITLMIIVLAIAIALTQIFPKDAETAFREALF
NVTSIMTGTGYSSADYMQWGPLLISLFFFIGLIGGCAGSTTCSIKIFRYQLLFASIRLQLRKIRSPNGVFIVRYEKRAVD
EEVLSSVMSFFMFFVLTLGLLAVALSLTGLDFITSLSGAATALSNVGPGLGDEIGPAGNFAGLNDTAKWLLSLGMLLGRL
ELLAVYAMLTLSFWRD

Sequences:

>Translated_496_residues
MRLTPAERRANPAHMLDLRPVGYVIGLLVAVLGAAMVLPMMIDIAEGRAHWPVFLQSALFTVLAGGLIAVACSNGVKEGL
TIQQTFILTTGVWVALPLFGAIPFVLGATEARFVDAFFEAMSGLTTTGSTVFTGLETLPKGLLLWRGILQWLGGIGIIVV
AMVFLPELRVGGMQIFKSEAFDTMGKILPRATQIASQISSIYLGLTMACALCYLALGLDAFDATVHALTTVSTGGFANYD
ASFGTFSGPPEYVASLFMILAALPFVRYVQMINGHTEPLWRDSQVRVFLITLMIIVLAIAIALTQIFPKDAETAFREALF
NVTSIMTGTGYSSADYMQWGPLLISLFFFIGLIGGCAGSTTCSIKIFRYQLLFASIRLQLRKIRSPNGVFIVRYEKRAVD
EEVLSSVMSFFMFFVLTLGLLAVALSLTGLDFITSLSGAATALSNVGPGLGDEIGPAGNFAGLNDTAKWLLSLGMLLGRL
ELLAVYAMLTLSFWRD
>Mature_496_residues
MRLTPAERRANPAHMLDLRPVGYVIGLLVAVLGAAMVLPMMIDIAEGRAHWPVFLQSALFTVLAGGLIAVACSNGVKEGL
TIQQTFILTTGVWVALPLFGAIPFVLGATEARFVDAFFEAMSGLTTTGSTVFTGLETLPKGLLLWRGILQWLGGIGIIVV
AMVFLPELRVGGMQIFKSEAFDTMGKILPRATQIASQISSIYLGLTMACALCYLALGLDAFDATVHALTTVSTGGFANYD
ASFGTFSGPPEYVASLFMILAALPFVRYVQMINGHTEPLWRDSQVRVFLITLMIIVLAIAIALTQIFPKDAETAFREALF
NVTSIMTGTGYSSADYMQWGPLLISLFFFIGLIGGCAGSTTCSIKIFRYQLLFASIRLQLRKIRSPNGVFIVRYEKRAVD
EEVLSSVMSFFMFFVLTLGLLAVALSLTGLDFITSLSGAATALSNVGPGLGDEIGPAGNFAGLNDTAKWLLSLGMLLGRL
ELLAVYAMLTLSFWRD

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=33.0595482546201, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1787626, Length=493, Percent_Identity=31.0344827586207, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53452; Mature: 53452

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]