Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 110679217

GI number: 110679217

Start: 1839670

End: 1841211

Strand: Direct

Name: xseA [H]

Synonym: RD1_1929

Alternate gene names: 110679217

Gene position: 1839670-1841211 (Clockwise)

Preceding gene: 110679215

Following gene: 110679219

Centisome position: 44.51

GC content: 64.01

Gene sequence:

>1542_bases
ATGGACTTGCTTGACGATCCCACACCGGGTCAGAATACGCCTGAATTCACGGTCAGTGAAATCTCGGGCGCTGTGAAACG
CACGCTGGAGGGAGAGTTCGGCCGCGTGCGGGTGCGCGGCGAGGTCAGCCGCGTGATCAGGGCGCGATCGGGCCATATGT
ATTACGACATCAAGGATGATCGGAACCAGCTTGCCTGCACTACATGGAAAGGGCAGGTCGCCCGGCTGAGCGTGATCCCC
GAAGAGGGGCTTGAGGTGGTCGTGACAGGGCGCATCACCGCCTATGGCGCACAGTCCAAGTACAACATGAATGTGGATGA
GGTAGCTGTCGCGGGCAAGGGCGCGCTGATGGCGCTGCTGGAAAAACGCAAGAAGCAGTTGCAGGCCGAGGGGCTGTTTG
AGGCATCGCGCAAACGTCCGTTGCCCTATCTGCCGGAAATCATCGGGGTTGTGACGTCGCCGACCGGGGCAGTGATCCGC
GATATTCTGCACCGCCTGCGCGACCGCTTCCCGCGCAAGGTGCTGATCTGGCCCGTGGCGGTTCAGGGTGAGAGATGCGC
GCCCGAGGTTGCGGCAGCCATCGCGGGCTTCAACGCGCTGGCACCGGGCGGCGCCTTGCCGCGCCCGGACCTGATCATCG
TGGCGCGCGGCGGTGGCTCGGTCGAGGACCTGTGGGGATTTAACGAGGAGAGCGTCGCGCGGGCAGCGGCAGCGTCAGAT
ATTCCGCTGATTTCCGCAGTGGGCCATGAAACCGACACCACGCTGATCGATTATGTGTCTGACAAACGTGCGCCTACACC
CACGGCGGCCGCTGAATTGGCGGTGCCGGTACGCCATGAGCTGATCGCATGGGTCGAGCAGCAGGATGCGCGCATGCGTC
AGGCGCTCAGCCAGGGGTTGACCCGCCGGGACCAGCGCCTGCGCGACATGGCCCGTGCCTTGCCGCGCCCGGACAGTCTG
CTGGAAAGCCCGCGTCAACTGGTCGACACGCGCGGCGCACGGCTGGCCCCGGCGCTGATGTCCGGGGTGCAGAGGCGCAA
GATACGTCTGGCGGATGTCAGCGGGTCACTGCGACCTGCGATGCTGACGCGCGCTGTGCAGGCAGAGGACCGGCAACTAA
AGGAAAAGGTGCGCCGTCTGCAACCGGCTTTGTTGCGCGCTCTGGCGACGCGCAAAGAGCAACTGGAAACACGGGTGCGG
CGATATCGCCCGGCAGTCCTTGAGCAGGAGTATCGACGCAAGAAACAGCATTTTGATGACGTGGTGCACCGTCTGGGCAA
AGTGGGCGAGCAGAACCTTGATGCGGCCCGCCGCAAACTCGACGCGTTGGGACGGCTGAATGAAACCCTCAGCTACAAGG
CCACGCTGGCGCGCGGTTTTGCCGTTGTGCGTGCGGATGGGGCCGTGGTGACAGACAGCAAGACCGCGAAAACGGCCAGC
AGTCTGGAAATCCAGTTCGCAGATGGCCGCGTGACGCTGGGCGGCAAACCCGCGTCGAGGAAATCAGCGGGCAAACCACC
GGAACAGGGGTCGCTGTTCTAA

Upstream 100 bases:

>100_bases
GCCGAGAATAAGAATGTTCATGAAGGGCTCCCGATCTGCTTGGCCTTAGGTTCAGGGCGTTCTAAGCTGGCGGGGAACCT
GTGACAACACCCGAGGCGCT

Downstream 100 bases:

>100_bases
AGCGTCATGTGAAGCCCTGTATCACGTAACGCTGCCTCTAATCAAAGATTTCAACGCGTTACGTGATGTTTGATGTTTCA
GGCATTTCGTCAGACGCGTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MDLLDDPTPGQNTPEFTVSEISGAVKRTLEGEFGRVRVRGEVSRVIRARSGHMYYDIKDDRNQLACTTWKGQVARLSVIP
EEGLEVVVTGRITAYGAQSKYNMNVDEVAVAGKGALMALLEKRKKQLQAEGLFEASRKRPLPYLPEIIGVVTSPTGAVIR
DILHRLRDRFPRKVLIWPVAVQGERCAPEVAAAIAGFNALAPGGALPRPDLIIVARGGGSVEDLWGFNEESVARAAAASD
IPLISAVGHETDTTLIDYVSDKRAPTPTAAAELAVPVRHELIAWVEQQDARMRQALSQGLTRRDQRLRDMARALPRPDSL
LESPRQLVDTRGARLAPALMSGVQRRKIRLADVSGSLRPAMLTRAVQAEDRQLKEKVRRLQPALLRALATRKEQLETRVR
RYRPAVLEQEYRRKKQHFDDVVHRLGKVGEQNLDAARRKLDALGRLNETLSYKATLARGFAVVRADGAVVTDSKTAKTAS
SLEIQFADGRVTLGGKPASRKSAGKPPEQGSLF

Sequences:

>Translated_513_residues
MDLLDDPTPGQNTPEFTVSEISGAVKRTLEGEFGRVRVRGEVSRVIRARSGHMYYDIKDDRNQLACTTWKGQVARLSVIP
EEGLEVVVTGRITAYGAQSKYNMNVDEVAVAGKGALMALLEKRKKQLQAEGLFEASRKRPLPYLPEIIGVVTSPTGAVIR
DILHRLRDRFPRKVLIWPVAVQGERCAPEVAAAIAGFNALAPGGALPRPDLIIVARGGGSVEDLWGFNEESVARAAAASD
IPLISAVGHETDTTLIDYVSDKRAPTPTAAAELAVPVRHELIAWVEQQDARMRQALSQGLTRRDQRLRDMARALPRPDSL
LESPRQLVDTRGARLAPALMSGVQRRKIRLADVSGSLRPAMLTRAVQAEDRQLKEKVRRLQPALLRALATRKEQLETRVR
RYRPAVLEQEYRRKKQHFDDVVHRLGKVGEQNLDAARRKLDALGRLNETLSYKATLARGFAVVRADGAVVTDSKTAKTAS
SLEIQFADGRVTLGGKPASRKSAGKPPEQGSLF
>Mature_513_residues
MDLLDDPTPGQNTPEFTVSEISGAVKRTLEGEFGRVRVRGEVSRVIRARSGHMYYDIKDDRNQLACTTWKGQVARLSVIP
EEGLEVVVTGRITAYGAQSKYNMNVDEVAVAGKGALMALLEKRKKQLQAEGLFEASRKRPLPYLPEIIGVVTSPTGAVIR
DILHRLRDRFPRKVLIWPVAVQGERCAPEVAAAIAGFNALAPGGALPRPDLIIVARGGGSVEDLWGFNEESVARAAAASD
IPLISAVGHETDTTLIDYVSDKRAPTPTAAAELAVPVRHELIAWVEQQDARMRQALSQGLTRRDQRLRDMARALPRPDSL
LESPRQLVDTRGARLAPALMSGVQRRKIRLADVSGSLRPAMLTRAVQAEDRQLKEKVRRLQPALLRALATRKEQLETRVR
RYRPAVLEQEYRRKKQHFDDVVHRLGKVGEQNLDAARRKLDALGRLNETLSYKATLARGFAVVRADGAVVTDSKTAKTAS
SLEIQFADGRVTLGGKPASRKSAGKPPEQGSLF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=486, Percent_Identity=34.5679012345679, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 56428; Mature: 56428

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLDDPTPGQNTPEFTVSEISGAVKRTLEGEFGRVRVRGEVSRVIRARSGHMYYDIKDD
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEECCC
RNQLACTTWKGQVARLSVIPEEGLEVVVTGRITAYGAQSKYNMNVDEVAVAGKGALMALL
CCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHH
EKRKKQLQAEGLFEASRKRPLPYLPEIIGVVTSPTGAVIRDILHRLRDRFPRKVLIWPVA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
VQGERCAPEVAAAIAGFNALAPGGALPRPDLIIVARGGGSVEDLWGFNEESVARAAAASD
ECCCCCCHHHHHHHHCCHHCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCC
IPLISAVGHETDTTLIDYVSDKRAPTPTAAAELAVPVRHELIAWVEQQDARMRQALSQGL
CCHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRDQRLRDMARALPRPDSLLESPRQLVDTRGARLAPALMSGVQRRKIRLADVSGSLRPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCHHH
MLTRAVQAEDRQLKEKVRRLQPALLRALATRKEQLETRVRRYRPAVLEQEYRRKKQHFDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVHRLGKVGEQNLDAARRKLDALGRLNETLSYKATLARGFAVVRADGAVVTDSKTAKTAS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCHHCCCC
SLEIQFADGRVTLGGKPASRKSAGKPPEQGSLF
CEEEEEECCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLLDDPTPGQNTPEFTVSEISGAVKRTLEGEFGRVRVRGEVSRVIRARSGHMYYDIKDD
CCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCEEEEECCC
RNQLACTTWKGQVARLSVIPEEGLEVVVTGRITAYGAQSKYNMNVDEVAVAGKGALMALL
CCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHH
EKRKKQLQAEGLFEASRKRPLPYLPEIIGVVTSPTGAVIRDILHRLRDRFPRKVLIWPVA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
VQGERCAPEVAAAIAGFNALAPGGALPRPDLIIVARGGGSVEDLWGFNEESVARAAAASD
ECCCCCCHHHHHHHHCCHHCCCCCCCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCC
IPLISAVGHETDTTLIDYVSDKRAPTPTAAAELAVPVRHELIAWVEQQDARMRQALSQGL
CCHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRRDQRLRDMARALPRPDSLLESPRQLVDTRGARLAPALMSGVQRRKIRLADVSGSLRPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCHHH
MLTRAVQAEDRQLKEKVRRLQPALLRALATRKEQLETRVRRYRPAVLEQEYRRKKQHFDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVHRLGKVGEQNLDAARRKLDALGRLNETLSYKATLARGFAVVRADGAVVTDSKTAKTAS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCEEEECCCHHCCCC
SLEIQFADGRVTLGGKPASRKSAGKPPEQGSLF
CEEEEEECCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA