Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 110679146

GI number: 110679146

Start: 1777253

End: 1778464

Strand: Direct

Name: yciC [H]

Synonym: RD1_1856

Alternate gene names: 110679146

Gene position: 1777253-1778464 (Clockwise)

Preceding gene: 110679144

Following gene: 110679147

Centisome position: 43.0

GC content: 57.92

Gene sequence:

>1212_bases
ATGTCACAGGCTCGTCTTCCCGTCACGGTTCTTTCCGGATTCTTGGGGGCTGGAAAAACCACGCTGTTGAACCGTGTTCT
GAACAATCGGGAAGGTCGGCGCGTTGCGGTCATCGTCAATGATATGTCCGAAGTGAACATCGACGCTGATCTGGTGCGGG
CGGATACACAGCTGAGCCGGACAGATGAGACGCTGGTCGAGATGTCGAACGGCTGTATTTGCTGCACGTTGCGCGATGAT
TTGCTGGACGAGGTGCGCCGTCTCGCCATTGAGGGTCGGTTTGACTACCTGCTCATCGAGTCCACCGGCATTTCGGAGCC
ATTGCCCGTGGCAGCGACATTCGATTTCCGGGATGAATTCGGCGATAGCCTGGCAGATGTGTCGCGACTGGATACGATGG
TCACGGTGGTGGATGCGGCGAATTTGCTGAATGATTACAGCAGCCATGATTTTCTGCGCGACCGCGGCGAGACGATGGGG
GAAGAGGATGACCGCACATTGGTTCACCTTCTTACCGACCAGATTGAATTCGCGGATGTCATTGTCCTGAACAAGGTCAC
GGATGCCGGTCCCGAACGTGTCGATGCTGCGCGCAAGATCATCCGCTCACTGAACGCGGATGCGAGGATCATCGAGACGG
ATCAATCCGATGTCCCGGCGGATGCGATCCTCGACACGGGCCTCTTTGATTTCGAAAAGGCCCATGAGCACCCGATGTGG
GCCAAAGAGCTGTATGGCTTTGCCGATCATGTTCCTGAAACGGAAGAATACGGTGTTGCCTCTTTTGTCTACCGGGCGCG
GCGTCCATTTGTTCCGGCGCAGATCCTCGCGGTTCTGAACGGTGATATGCCGGGCGTCATCCGGGCCAAGGGCCATTTCT
GGATCGCAACGCGCCCTGACTGGATTGCCGAGTTTTCACTGGCGGGGTCGTTATCTACGGTGAAACCGCTGGGGACGTGG
TGGGCCTCTGTGTCAAAGGAGAGCTGGCCTGCGCATGAAAGCGTGAAAAGCTATTTGCAGGCGCATTGGCAAGAACCTTG
GGGGGACCGCCGTCAGGAACTGGTGTTTATCGGGGCAGGGATCGACTGGCCTTCGCTGAAATCACGCCTTGATGGCTGTC
TTGTGCCTGCGTCGGTGGCCCCGGGGCCGGATGACTTGCCGGATTATCCCGACCCGTTCCCCATGTGGCGCCGTGCGGAA
CAAGCGGCATGA

Upstream 100 bases:

>100_bases
GCTTTTCCTCTGACGTCCCACATTACGTAACAATTGCTGTTGCAATAGTCTAGTAACTGAGTAAGTTGCGTAATATGCGA
TCTAAGCTTTGGAGCACAGA

Downstream 100 bases:

>100_bases
CGTTCGTGCGTGAAGTTGTGCGAGACGCCGCCGTGGGGGTCGCTGTTGCGGACCGGCCTGAAGACCTCGTGGCCATCCGG
AAACCCGGTTGTGCCGCTGC

Product: cobalamin synthesis protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSQARLPVTVLSGFLGAGKTTLLNRVLNNREGRRVAVIVNDMSEVNIDADLVRADTQLSRTDETLVEMSNGCICCTLRDD
LLDEVRRLAIEGRFDYLLIESTGISEPLPVAATFDFRDEFGDSLADVSRLDTMVTVVDAANLLNDYSSHDFLRDRGETMG
EEDDRTLVHLLTDQIEFADVIVLNKVTDAGPERVDAARKIIRSLNADARIIETDQSDVPADAILDTGLFDFEKAHEHPMW
AKELYGFADHVPETEEYGVASFVYRARRPFVPAQILAVLNGDMPGVIRAKGHFWIATRPDWIAEFSLAGSLSTVKPLGTW
WASVSKESWPAHESVKSYLQAHWQEPWGDRRQELVFIGAGIDWPSLKSRLDGCLVPASVAPGPDDLPDYPDPFPMWRRAE
QAA

Sequences:

>Translated_403_residues
MSQARLPVTVLSGFLGAGKTTLLNRVLNNREGRRVAVIVNDMSEVNIDADLVRADTQLSRTDETLVEMSNGCICCTLRDD
LLDEVRRLAIEGRFDYLLIESTGISEPLPVAATFDFRDEFGDSLADVSRLDTMVTVVDAANLLNDYSSHDFLRDRGETMG
EEDDRTLVHLLTDQIEFADVIVLNKVTDAGPERVDAARKIIRSLNADARIIETDQSDVPADAILDTGLFDFEKAHEHPMW
AKELYGFADHVPETEEYGVASFVYRARRPFVPAQILAVLNGDMPGVIRAKGHFWIATRPDWIAEFSLAGSLSTVKPLGTW
WASVSKESWPAHESVKSYLQAHWQEPWGDRRQELVFIGAGIDWPSLKSRLDGCLVPASVAPGPDDLPDYPDPFPMWRRAE
QAA
>Mature_402_residues
SQARLPVTVLSGFLGAGKTTLLNRVLNNREGRRVAVIVNDMSEVNIDADLVRADTQLSRTDETLVEMSNGCICCTLRDDL
LDEVRRLAIEGRFDYLLIESTGISEPLPVAATFDFRDEFGDSLADVSRLDTMVTVVDAANLLNDYSSHDFLRDRGETMGE
EDDRTLVHLLTDQIEFADVIVLNKVTDAGPERVDAARKIIRSLNADARIIETDQSDVPADAILDTGLFDFEKAHEHPMWA
KELYGFADHVPETEEYGVASFVYRARRPFVPAQILAVLNGDMPGVIRAKGHFWIATRPDWIAEFSLAGSLSTVKPLGTWW
ASVSKESWPAHESVKSYLQAHWQEPWGDRRQELVFIGAGIDWPSLKSRLDGCLVPASVAPGPDDLPDYPDPFPMWRRAEQ
AA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=263, Percent_Identity=34.9809885931559, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI126722884, Length=263, Percent_Identity=34.9809885931559, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI148727351, Length=263, Percent_Identity=34.6007604562738, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI146231952, Length=263, Percent_Identity=34.2205323193916, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI223941779, Length=218, Percent_Identity=36.697247706422, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI223941776, Length=251, Percent_Identity=34.2629482071713, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI119120938, Length=138, Percent_Identity=38.4057971014493, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI87082430, Length=373, Percent_Identity=26.0053619302949, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788499, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=237, Percent_Identity=29.1139240506329, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 44928; Mature: 44797

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQARLPVTVLSGFLGAGKTTLLNRVLNNREGRRVAVIVNDMSEVNIDADLVRADTQLSR
CCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCHHHHH
TDETLVEMSNGCICCTLRDDLLDEVRRLAIEGRFDYLLIESTGISEPLPVAATFDFRDEF
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHH
GDSLADVSRLDTMVTVVDAANLLNDYSSHDFLRDRGETMGEEDDRTLVHLLTDQIEFADV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHE
IVLNKVTDAGPERVDAARKIIRSLNADARIIETDQSDVPADAILDTGLFDFEKAHEHPMW
EEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHCCCCH
AKELYGFADHVPETEEYGVASFVYRARRPFVPAQILAVLNGDMPGVIRAKGHFWIATRPD
HHHHHHHHHCCCCCHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCEEEEECCC
WIAEFSLAGSLSTVKPLGTWWASVSKESWPAHESVKSYLQAHWQEPWGDRRQELVFIGAG
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
IDWPSLKSRLDGCLVPASVAPGPDDLPDYPDPFPMWRRAEQAA
CCCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SQARLPVTVLSGFLGAGKTTLLNRVLNNREGRRVAVIVNDMSEVNIDADLVRADTQLSR
CCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHCHHHHH
TDETLVEMSNGCICCTLRDDLLDEVRRLAIEGRFDYLLIESTGISEPLPVAATFDFRDEF
HHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHH
GDSLADVSRLDTMVTVVDAANLLNDYSSHDFLRDRGETMGEEDDRTLVHLLTDQIEFADV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHE
IVLNKVTDAGPERVDAARKIIRSLNADARIIETDQSDVPADAILDTGLFDFEKAHEHPMW
EEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHCCCCH
AKELYGFADHVPETEEYGVASFVYRARRPFVPAQILAVLNGDMPGVIRAKGHFWIATRPD
HHHHHHHHHCCCCCHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCEEEEECCC
WIAEFSLAGSLSTVKPLGTWWASVSKESWPAHESVKSYLQAHWQEPWGDRRQELVFIGAG
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
IDWPSLKSRLDGCLVPASVAPGPDDLPDYPDPFPMWRRAEQAA
CCCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]