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The map label for this gene is cobT

Identifier: 110679122

GI number: 110679122

Start: 1751460

End: 1752473

Strand: Direct

Name: cobT

Synonym: RD1_1827

Alternate gene names: 110679122

Gene position: 1751460-1752473 (Clockwise)

Preceding gene: 110679120

Following gene: 110679125

Centisome position: 42.38

GC content: 65.78

Gene sequence:

>1014_bases
ATGACGGCTGCTTTTTCCACCCTTGATGAGGTCCGCGATATCCTGCGTGCGCTCCCCGAAAGTGATGCTGAGAGCATTGA
CGATGCGGCTGCGCGTAATGGGCAGTTGACCAAACCCCCCGGTGCCTTGGGCCGTCTGGAAGCTCTGGCGATCTGGTATG
CAGGCTGGCGCGGCGTTGCGACGCCACGCATTGAGACCCCGCAGATCATCGTTTTTGCGGGCAACCATGGGATCGCTGCG
CAAGGTGTGTCGGCCTTTCCGGCGGAAGTGACGGCGCAGATGGTGCTGAATTTCCAGCATGGCGGGGCGGCGATCAATCA
GTTGGCGGCGACATTCGGCGCCAAGCTGGACGTGCACGCGCTGGCACTTGAGCAACCCACGGCGGATTTCACTCAAGCCC
CCGCGATGTCGGAGGCTGAGGTGATCGACGCGCTCCATACGGGTTGGCAGGCGGTCGATGCGGCGGCGGATGTCCTGATC
GTCGGAGAGATGGGGATCGGCAACACGACCTGCGCCGCTGCCCTTGCCGCTGCCTGTTTCGGGGGCGCACCTGCCGACTG
GGTGGGGCGCGGCACGGGGGTCGATGACGCGGGTCTGGCCATCAAGCAGCGGGTTGTGGCCGAAGGTCTGGCGCGGCACG
CAACGGTGCATGACGGTCTGGAGAAGCTGCGCTGTCTGGGCGGGCGTGAAGTTGCCGCAATGGCGGGTGCCATCCTGCGG
GCGCGTGTGCTGCGGATCCCGGTGCTGCTGGATGGGTTCATCTGCTGCGCGGCGGCGGGCAGTTTGATGCATACGGCACC
GGATGCGCTGGAACATTGCGTGGCGGGGCATTTGAGCGCCGAAGGGTCACACGACCGGCTGTTGCAGGCCATCGGGAAAC
CGCCCTTGCTCTCCCTGGGCCTTCGCCTTGGGGAGGCCTCTGGCGCGGCTTTGTCCCTGGCGGTGCTGCAAGGGGCCGTT
GCCTGCCTCAGCGGCATGGCAACCTTTGCCGAAGCAGGCGTTGCCGACGGATGA

Upstream 100 bases:

>100_bases
GGATCATGTCGGTTTTCATGCGCCTGCGGCCTCTTCACATCTTGCTGGTTGCGTCCCTTGGGGTAAAGAGGACGCAACAA
TCATGCAACGGGGTTCTCTG

Downstream 100 bases:

>100_bases
GCCGGGCTGAGGGCTCAACCGTCGGTGTTTTTTGCGGAGATTGAGCGGCTTAAAATGGCAGTTTCCAACTCCTTTTGCAG
CTCTTTGGCCCGCGCGACAT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTAAFSTLDEVRDILRALPESDAESIDDAAARNGQLTKPPGALGRLEALAIWYAGWRGVATPRIETPQIIVFAGNHGIAA
QGVSAFPAEVTAQMVLNFQHGGAAINQLAATFGAKLDVHALALEQPTADFTQAPAMSEAEVIDALHTGWQAVDAAADVLI
VGEMGIGNTTCAAALAAACFGGAPADWVGRGTGVDDAGLAIKQRVVAEGLARHATVHDGLEKLRCLGGREVAAMAGAILR
ARVLRIPVLLDGFICCAAAGSLMHTAPDALEHCVAGHLSAEGSHDRLLQAIGKPPLLSLGLRLGEASGAALSLAVLQGAV
ACLSGMATFAEAGVADG

Sequences:

>Translated_337_residues
MTAAFSTLDEVRDILRALPESDAESIDDAAARNGQLTKPPGALGRLEALAIWYAGWRGVATPRIETPQIIVFAGNHGIAA
QGVSAFPAEVTAQMVLNFQHGGAAINQLAATFGAKLDVHALALEQPTADFTQAPAMSEAEVIDALHTGWQAVDAAADVLI
VGEMGIGNTTCAAALAAACFGGAPADWVGRGTGVDDAGLAIKQRVVAEGLARHATVHDGLEKLRCLGGREVAAMAGAILR
ARVLRIPVLLDGFICCAAAGSLMHTAPDALEHCVAGHLSAEGSHDRLLQAIGKPPLLSLGLRLGEASGAALSLAVLQGAV
ACLSGMATFAEAGVADG
>Mature_336_residues
TAAFSTLDEVRDILRALPESDAESIDDAAARNGQLTKPPGALGRLEALAIWYAGWRGVATPRIETPQIIVFAGNHGIAAQ
GVSAFPAEVTAQMVLNFQHGGAAINQLAATFGAKLDVHALALEQPTADFTQAPAMSEAEVIDALHTGWQAVDAAADVLIV
GEMGIGNTTCAAALAAACFGGAPADWVGRGTGVDDAGLAIKQRVVAEGLARHATVHDGLEKLRCLGGREVAAMAGAILRA
RVLRIPVLLDGFICCAAAGSLMHTAPDALEHCVAGHLSAEGSHDRLLQAIGKPPLLSLGLRLGEASGAALSLAVLQGAVA
CLSGMATFAEAGVADG

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=342, Percent_Identity=31.2865497076023, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_ROSDO (Q169A0)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682129.1
- ProteinModelPortal:   Q169A0
- SMR:   Q169A0
- STRING:   Q169A0
- GeneID:   4196884
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1827
- NMPDR:   fig|375451.6.peg.1710
- eggNOG:   COG2038
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- PhylomeDB:   Q169A0
- ProtClustDB:   PRK00105
- BioCyc:   RDEN375451:RD1_1827-MONOMER
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 34236; Mature: 34105

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: ACT_SITE 305-305

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAFSTLDEVRDILRALPESDAESIDDAAARNGQLTKPPGALGRLEALAIWYAGWRGVA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
TPRIETPQIIVFAGNHGIAAQGVSAFPAEVTAQMVLNFQHGGAAINQLAATFGAKLDVHA
CCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEE
LALEQPTADFTQAPAMSEAEVIDALHTGWQAVDAAADVLIVGEMGIGNTTCAAALAAACF
EEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHH
GGAPADWVGRGTGVDDAGLAIKQRVVAEGLARHATVHDGLEKLRCLGGREVAAMAGAILR
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARVLRIPVLLDGFICCAAAGSLMHTAPDALEHCVAGHLSAEGSHDRLLQAIGKPPLLSLG
HHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHH
LRLGEASGAALSLAVLQGAVACLSGMATFAEAGVADG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAAFSTLDEVRDILRALPESDAESIDDAAARNGQLTKPPGALGRLEALAIWYAGWRGVA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
TPRIETPQIIVFAGNHGIAAQGVSAFPAEVTAQMVLNFQHGGAAINQLAATFGAKLDVHA
CCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEE
LALEQPTADFTQAPAMSEAEVIDALHTGWQAVDAAADVLIVGEMGIGNTTCAAALAAACF
EEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHH
GGAPADWVGRGTGVDDAGLAIKQRVVAEGLARHATVHDGLEKLRCLGGREVAAMAGAILR
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARVLRIPVLLDGFICCAAAGSLMHTAPDALEHCVAGHLSAEGSHDRLLQAIGKPPLLSLG
HHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHH
LRLGEASGAALSLAVLQGAVACLSGMATFAEAGVADG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA